Norquinadoline A
AlkaPlorer ID: AK042534
Synonym: None
IUPAC Name: (4R)-4-[[(2S,3aR,4S)-4-hydroxy-2-methyl-1-oxo-3,3a-dihydro-2H-imidazo[1,2-a]indol-4-yl]methyl]-1-propan-2-ylidene-4H-pyrazino[2,1-b]quinazoline-3,6-dione
Structure
SMILES: CC(C)=C1N=C(O)[C@@H](C[C@]2(O)C3=CC=CC=C3N3C(=O)[C@H](C)N[C@H]32)N2C1=NC1=CC=CC=C1C2=O
InChI: InChI=1S/C26H25N5O4/c1-13(2)20-21-28-17-10-6-4-8-15(17)24(34)30(21)19(22(32)29-20)12-26(35)16-9-5-7-11-18(16)31-23(33)14(3)27-25(26)31/h4-11,14,19,25,27,35H,12H2,1-3H3,(H,29,32)/t14-,19+,25+,26-/m0/s1
InChIKey: XMLDSNFLVFBRQG-WGZOSGDWSA-N
Reference
Antiviral Alkaloids Produced by the Mangrove-Derived Fungus <i>Cladosporium</i> sp. PJX-41
PubChem CID: 71725622
LOTUS: LTS0118399
NPASS: NPC471155
{NPAtlas: NPA002252
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Cladosporium sp. | Cladosporium | Cladosporiaceae | Cladosporiales | Dothideomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 471.51700000000017
TPSA？: 120.05
MolLogP？: 2.6009
Number of H-Donors: 3
Number of H-Acceptors: 7
RingCount: 6
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Influenza A virus | Influenza A virus | IC50 | 82000.0 | nM | 10.1016/j.ejmech.2022.114117 |
| Influenza A virus | Influenza A virus | IC50 | 82000.0 | nM | 10.1021/np400200k |