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name Structure Reference Source Properties Activities Metabolism

2,2'-dipyridyldisulfide

AlkaPlorer ID: AK043097

Synonym: 'SMR000473199', "2,2'-dithiodipyridine", 'MLS001143364'

IUPAC Name: 2-(pyridin-2-yldisulfanyl)pyridine

Structure

SMILES: C1=CC=C(SSC2=CC=CC=N2)N=C1

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InChI: InChI=1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H

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InChIKey: HAXFWIACAGNFHA-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Allium stipitatum Allium Amaryllidaceae Asparagales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 220.32200000000003

TPSA？: 25.78

MolLogP？: 3.2760000000000016

Number of H-Donors: 0

Number of H-Acceptors: 4

RingCount: 2

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bos taurus Mitochondrial peptide methionine sulfoxide reductase EC50 103879.0 nM None
Homo sapiens Chromobox protein homolog 1 Potency 11220.2 nM None
Homo sapiens DNA dC->dU-editing enzyme APOBEC-3G IC50 3880.0 nM None
Homo sapiens DNA polymerase iota Potency 22387.2 nM None
Homo sapiens Flap endonuclease 1 Potency 89125.1 nM None
Homo sapiens Geminin Potency 2310.9 nM None
Homo sapiens Geminin Potency 29092.9 nM None
Homo sapiens Glucose-6-phosphate 1-dehydrogenase IC50 80000.0 nM None
Homo sapiens Glutaminase kidney isoform, mitochondrial Potency 10000.0 nM None
Homo sapiens Glycoprotein hormones alpha chain Potency 10000.0 nM None
Homo sapiens HepG2 Potency 501.2 nM None
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 IC50 650.0 nM 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Inhibition 50.0 % 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Inhibition nan % 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 IC50 2700.0 nM 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 Inhibition 50.0 % 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 Inhibition nan % 10.1016/j.bmcl.2018.02.043
Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic Potency 25929.0 nM None
Homo sapiens Lysine-specific demethylase 4A Potency 3981.1 nM None
Homo sapiens Mothers against decapentaplegic homolog 3 Potency 22387.2 nM None
Homo sapiens Probable DNA dC->dU-editing enzyme APOBEC-3A IC50 100000.0 nM None
Homo sapiens Regulator of G-protein signaling 4 Potency 56234.1 nM None
Homo sapiens Serine/threonine-protein kinase PLK1 Potency 670.2 nM None
Homo sapiens TAR DNA-binding protein 43 Potency 12589.3 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 2909.3 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 4610.9 nM None
Homo sapiens Vitamin D receptor Potency 3162.3 nM None
Homo sapiens Werner syndrome ATP-dependent helicase Potency 22387.2 nM None
Human immunodeficiency virus 1 Aberrant vpr protein Potency 44668.4 nM None
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity nan None 10.1016/j.bmc.2016.09.028
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity nan None 10.1021/jm960375o
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 4.0 None 10.1016/j.bmc.2016.09.028
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 55.1 None 10.1021/jm960375o
Plasmodium berghei Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase IC50 9820.0 nM None
Plasmodium berghei Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase IC50 60800.0 nM None
Plasmodium berghei Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase IC50 64100.0 nM None
Simian virus 40 Large T antigen IC50 100000.0 nM None
Trypanosoma brucei brucei (strain 927/4 GUTat10.1) Putative uncharacterized protein Potency 25118.9 nM None
None Unchecked IC50 25000.0 nM None
None Unchecked Potency 23109.3 nM None
None Unchecked Potency 39810.7 nM None

Metabolism Information