Cularidine
AlkaPlorer ID: AK043256
Synonym: None
IUPAC Name: (10S)-5,6-dimethoxy-11-methyl-2-oxa-11-azatetracyclo[8.7.1.03,8.014,18]octadeca-1(17),3,5,7,14(18),15-hexaen-17-ol
Structure
SMILES: COC1=CC2=C(C=C1OC)OC1=C(O)C=CC3=C1[C@H](C2)N(C)CC3
InChI: InChI=1S/C19H21NO4/c1-20-7-6-11-4-5-14(21)19-18(11)13(20)8-12-9-16(22-2)17(23-3)10-15(12)24-19/h4-5,9-10,13,21H,6-8H2,1-3H3/t13-/m0/s1
InChIKey: ITGZZZYNPULRNZ-ZDUSSCGKSA-N
Reference
Fertilisation of Corydalis claviculata
PubChem CID: 442203
CAS: 5140-50-1
LOTUS: LTS0257751
SuperNatural Ⅲ: SN0154727-01
NPASS: NPC152680
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Dicentra cucullaria | Dicentra | Papaveraceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 327.3800000000001
TPSA？: 51.16
MolLogP？: 3.286800000000002
Number of H-Donors: 1
Number of H-Acceptors: 5
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Rattus norvegicus | Dopamine D1 receptor | IC50 | 800.0 | nM | 10.1021/jm060959i |
| Rattus norvegicus | Dopamine D2 receptor | IC50 | 300.0 | nM | 10.1021/jm060959i |
| Rattus norvegicus | Dopamine transporter | IC50 | 41000.0 | nM | 10.1021/jm060959i |
| Rattus norvegicus | Dopamine transporter | IC50 | 41200.0 | nM | 10.1021/np50124a001 |
| None | Unchecked | Ratio IC50 | 0.002 | None | 10.1021/np50124a001 |
| None | Unchecked | Ratio IC50 | 0.008 | None | 10.1021/np50124a001 |