Molecule

Argyrin C

AlkaPlorer ID: AK043708

Synonym: None

IUPAC Name: (4S,7S,13R,22R)-4-(1H-indol-3-ylmethyl)-7-[(4-methoxy-2-methyl-1H-indol-3-yl)methyl]-13,18,22-trimethyl-16-methylidene-24-thia-3,6,9,12,15,18,21,26-octazabicyclo[21.2.1]hexacosa-1(25),23(26)-diene-2,5,8,11,14,17,20-heptone

Structure

SMILES: C=C1N=C(O)[C@@H](C)N=C(O)CN=C(O)[C@H](CC2=C(C)NC3=C2C(OC)=CC=C3)N=C(O)[C@H](CC2=CNC3=CC=CC=C23)N=C(O)C2=CSC(=N2)[C@@H](C)N=C(O)CN(C)C1=O

InChI: InChI=1S/C41H46N10O8S/c1-20-26(35-28(44-20)12-9-13-32(35)59-6)15-30-37(55)43-17-33(52)45-21(2)36(54)47-23(4)41(58)51(5)18-34(53)46-22(3)40-50-31(19-60-40)39(57)48-29(38(56)49-30)14-24-16-42-27-11-8-7-10-25(24)27/h7-13,16,19,21-22,29-30,42,44H,4,14-15,17-18H2,1-3,5-6H3,(H,43,55)(H,45,52)(H,46,53)(H,47,54)(H,48,57)(H,49,56)/t21-,22-,29+,30+/m1/s1

InChIKey: YCCLYOWBNOMWGI-UFDDTGEXSA-N

Reference

Argyrins, Immunosuppressive Cyclic Peptides from Myxobacteria. I. Production, Isolation, Physico-chemical and Biological Properties.

PubChem CID: 10876612

LOTUS: LTS0223984

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NPAtlas: NPA019021

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
None	Gephyra	Pyralidae	Lepidoptera	Insecta	Arthropoda	Metazoa	Eukaryota

Properties Information

Molecule Weight: 838.9479999999999

TPSA？: 269.55

MolLogP？: 6.167620000000005

Number of H-Donors: 8

Number of H-Acceptors: 10

RingCount: 6

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Pseudomonas aeruginosa	Pseudomonas aeruginosa	IC50	0.1	ug.mL-1	10.1021/acs.jmedchem.5b01698