Altematamide A
AlkaPlorer ID: AK044049
Synonym: None
IUPAC Name: (2S)-4-methyl-2-(methylamino)-N-[2-(2,5,6-tribromo-1-methylindol-3-yl)ethyl]pentanamide
Structure
SMILES: CN[C@@H](CC(C)C)C(O)=NCCC1=C(Br)N(C)C2=CC(Br)=C(Br)C=C12
InChI: InChI=1S/C18H24Br3N3O/c1-10(2)7-15(22-3)18(25)23-6-5-11-12-8-13(19)14(20)9-16(12)24(4)17(11)21/h8-10,15,22H,5-7H2,1-4H3,(H,23,25)/t15-/m0/s1
InChIKey: KHRZQNJMQDSRQY-HNNXBMFYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Amathia alternata | Amathia | Vesiculariidae | Ctenostomatida | Gymnolaemata | Bryozoa | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 538.1220000000001
TPSA？: 49.55
MolLogP？: 5.598900000000005
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | MIC | 4.0 | ug.mL-1 | 10.1016/j.ejmech.2017.04.003 |
| Bacillus subtilis | Bacillus subtilis | MIC | 4.0 | ug.mL-1 | 10.1021/np970042+ |
| Enterococcus faecalis | Enterococcus faecalis | MIC | 4.0 | ug.mL-1 | 10.1016/j.ejmech.2017.04.003 |
| Enterococcus faecalis | Enterococcus faecalis | MIC | 4.0 | ug.mL-1 | 10.1021/np970042+ |
| Enterococcus faecium | Enterococcus faecium | MIC | 4.0 | ug.mL-1 | 10.1016/j.ejmech.2017.04.003 |
| Enterococcus faecium | Enterococcus faecium | MIC | 4.0 | ug.mL-1 | 10.1021/np970042+ |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 4.0 | ug.mL-1 | 10.1016/j.ejmech.2017.04.003 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 4.0 | ug.mL-1 | 10.1021/np970042+ |
| Staphylococcus epidermidis | Staphylococcus epidermidis | MIC | 4.0 | ug.mL-1 | 10.1021/np970042+ |
| Staphylococcus haemolyticus | Staphylococcus haemolyticus | MIC | 4.0 | ug.mL-1 | 10.1016/j.ejmech.2017.04.003 |
| Staphylococcus haemolyticus | Staphylococcus haemolyticus | MIC | 4.0 | ug.mL-1 | 10.1021/np970042+ |
| Streptococcus pyogenes | Streptococcus pyogenes | MIC | 4.0 | ug.mL-1 | 10.1016/j.ejmech.2017.04.003 |
| Streptococcus pyogenes | Streptococcus pyogenes | MIC | 4.0 | ug.mL-1 | 10.1021/np970042+ |