Molecule

Arcyriaflavin A; 2,10-Dihydroxy

AlkaPlorer ID: AK044296

Synonym: Arcyriaflavin C

IUPAC Name: 6,20-dihydroxy-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione

Structure

SMILES: O=C1N=C(O)C2=C3C4=CC=C(O)C=C4NC3=C3NC4=CC(O)=CC=C4C3=C12

InChI: InChI=1S/C20H11N3O4/c24-7-1-3-9-11(5-7)21-17-13(9)15-16(20(27)23-19(15)26)14-10-4-2-8(25)6-12(10)22-18(14)17/h1-6,21-22,24-25H,(H,23,26,27)

InChIKey: COUUDSNRXUXNDW-UHFFFAOYSA-N

Reference

Synthesis, determination of stereochemistry, and evaluation of new bisindole alkaloids from the myxomycete Arcyria ferruginea: An approach for Wnt signal inhibitor

PubChem CID: 5482346

CAS: 73697-65-1

LOTUS: LTS0030183

NPASS: NPC132329

COCONUT: CNP0294386

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Metatrichia vesparium	Metatrichia	Trichiidae	Trichiida	Eumycetozoa	Evosea	None	Eukaryota
Arcyria ferruginea	Arcyria	Trichiidae	Trichiida	Eumycetozoa	Evosea	None	Eukaryota
None	Tubifera	Reticulariaceae	Liceales	Eumycetozoa	Evosea	None	Eukaryota
Streptosporangium vulgare	Streptosporangium	Streptosporangiaceae	Streptosporangiales	Actinomycetes	Actinomycetota	None	Bacteria
Arcyria denudata	Arcyria	Trichiidae	Trichiida	Eumycetozoa	Evosea	None	Eukaryota
Arcyria ferruginea	Arcyria	Trichiidae	Trichiida	Eumycetozoa	Evosea	None	Eukaryota
Arcyria denudata	Arcyria	Trichiidae	Trichiida	Eumycetozoa	Evosea	None	Eukaryota

Properties Information

Molecule Weight: 357.3250000000001

TPSA？: 121.7

MolLogP？: 3.8252000000000006

Number of H-Donors: 5

Number of H-Acceptors: 3

RingCount: 6

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	HeLa	Concentration	10.0	ng ml-1	10.1016/s0960-894x(03)00592-4
Homo sapiens	HeLa	Concentration	100.0	ng ml-1	10.1016/s0960-894x(03)00592-4
Homo sapiens	Zinc finger protein GLI1	IC50	1800.0	nM	10.1021/jm801420y
Homo sapiens	Zinc finger protein GLI2	IC50	2700.0	nM	10.1021/jm801420y
None	Unchecked	Activity	nan	None	10.1016/j.bmcl.2007.05.033