Molecule

Nocazoline A

AlkaPlorer ID: AK044433

Synonym: None

IUPAC Name: 2-[(4R)-4-(hydroxymethyl)-4,5-dihydro-1,3-oxazol-2-yl]phenol

SMILES: OC[C@@H]1COC(C2=CC=CC=C2O)=N1

InChI: InChI=1S/C10H11NO3/c12-5-7-6-14-10(11-7)8-3-1-2-4-9(8)13/h1-4,7,12-13H,5-6H2/t7-/m1/s1

InChIKey: KSWPNAGSVMAXMO-SSDOTTSWSA-N

PubChem CID: 136099212

LOTUS: LTS0219076

NPASS: NPC5932

{

NPAtlas: NPA002496

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Nocardiopsis dassonvillei	Nocardiopsis	Nocardiopsaceae	Streptosporangiales	Actinomycetes	Actinomycetota	None	Bacteria
Streptomyces sp. RM-14-6	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria

Molecule Weight: 193.202

TPSA？: 62.05

MolLogP？: 0.5299000000000003

Number of H-Donors: 2

Number of H-Acceptors: 4

RingCount: 2

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Escherichia coli	Escherichia coli	Activity	nan	None	10.1021/acs.jnatprod.6b00948
Escherichia coli	Escherichia coli	Activity	nan	None	10.1021/acs.jnatprod.6b00949
Homo sapiens	A549	Activity	nan	None	10.1021/acs.jnatprod.6b00948
Homo sapiens	A549	Activity	nan	None	10.1021/acs.jnatprod.6b00949
Homo sapiens	A549	IC5	100.0	uM	10.1021/np200597m
Homo sapiens	HL-60	IC50	100000.0	nM	10.1021/np200597m
Micrococcus luteus	Micrococcus luteus	Activity	nan	None	10.1021/acs.jnatprod.6b00948
Micrococcus luteus	Micrococcus luteus	Activity	nan	None	10.1021/acs.jnatprod.6b00949
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Activity	nan	None	10.1021/acs.jnatprod.6b00948
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Activity	nan	None	10.1021/acs.jnatprod.6b00949
Salmonella enterica	Salmonella enterica	Activity	nan	None	10.1021/acs.jnatprod.6b00948
Staphylococcus aureus	Staphylococcus aureus	Activity	nan	None	10.1021/acs.jnatprod.6b00948
Staphylococcus aureus	Staphylococcus aureus	Activity	nan	None	10.1021/acs.jnatprod.6b00949
None	Unchecked	Activity	nan	None	10.1021/acs.jnatprod.6b00948
None	Unchecked	Activity	nan	None	10.1021/acs.jnatprod.6b00949