N-Methyl 1,4-Dideoxy-1,4-imino-D-arabinitol
AlkaPlorer ID: AK044534
Synonym: ''
IUPAC Name: (2R,3R,4R)-2-(hydroxymethyl)-1-methylpyrrolidine-3,4-diol
Structure
SMILES: CN1C[C@@H](O)[C@H](O)[C@H]1CO
InChI: InChI=1S/C6H13NO3/c1-7-2-5(9)6(10)4(7)3-8/h4-6,8-10H,2-3H2,1H3/t4-,5-,6-/m1/s1
InChIKey: UBVOJPDDTVFNFJ-HSUXUTPPSA-N
Reference
New Sugar-Mimic Alkaloids from the Pods of <i>Angylocalyx pynaertii</i>
PubChem CID: 451992
CAS: 117956-55-5
LOTUS: LTS0154187
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Angylocalyx pynaertii | Angylocalyx | Fabaceae | Fabales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 147.17399999999998
TPSA？: 63.93000000000001
MolLogP？: -1.9855
Number of H-Donors: 3
Number of H-Acceptors: 4
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Maltase-glucoamylase | IC50 | 500000.0 | nM | 10.1021/jm00013a012 |
| Homo sapiens | MOLT-4 | CC50 | 100000.0 | ug.mL-1 | 10.1021/jm00013a012 |
| Homo sapiens | MOLT-4 | EC50 | 100000.0 | ug.mL-1 | 10.1021/jm00013a012 |
| Homo sapiens | MT4 | CC50 | 100000.0 | ug.mL-1 | 10.1021/jm00013a012 |
| Homo sapiens | MT4 | EC50 | 100000.0 | ug.mL-1 | 10.1021/jm00013a012 |
| Rattus norvegicus | Alpha-mannosidase 2C1 | IC50 | 50000.0 | nM | 10.1021/jm00013a012 |
| Rattus norvegicus | Lactase-glycosylceramidase | IC50 | 50000.0 | nM | 10.1021/jm00013a012 |
| Rattus norvegicus | Mannosidase 2 alpha 1 | IC50 | 64000.0 | nM | 10.1021/jm00013a012 |
| Rattus norvegicus | Mannosidase 2 alpha 1 | Ki | 51000.0 | nM | 10.1021/jm00013a012 |
| Rattus norvegicus | Mannosidase 2, alpha B1 | IC50 | 360000.0 | nM | 10.1021/jm00013a012 |
| Rattus norvegicus | Sucrase-isomaltase | IC50 | 70000.0 | nM | 10.1021/jm00013a012 |
| Rattus norvegicus | Sucrase-isomaltase | IC50 | 100000.0 | nM | 10.1021/jm00013a012 |
| Rattus norvegicus | Trehalase | IC50 | 50000.0 | nM | 10.1021/jm00013a012 |
| None | Unchecked | IC50 | 50000.0 | nM | 10.1021/jm00013a012 |
| None | Unchecked | IC50 | 180000.0 | nM | 10.1021/jm00013a012 |
| None | Unchecked | IC50 | 310000.0 | nM | 10.1021/jm00013a012 |
| None | Unchecked | Ki | 150000.0 | nM | 10.1021/jm00013a012 |