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name Structure Reference Source Properties Activities Metabolism

2-phenylquinoline

AlkaPlorer ID: AK045066

Synonym: '2-Phenylquinoline', 'MLS001050066', 'SMR000112441'

IUPAC Name: 2-phenylquinoline

Structure

SMILES: C1=CC=C(C2=CC=C3C=CC=CC3=N2)C=C1

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InChI: InChI=1S/C15H11N/c1-2-6-12(7-3-1)15-11-10-13-8-4-5-9-14(13)16-15/h1-11H

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InChIKey: FSEXLNMNADBYJU-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain

Properties Information

Molecule Weight: 205.26

TPSA？: 12.89

MolLogP？: 3.9018000000000015

Number of H-Donors: 0

Number of H-Acceptors: 1

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Aspergillus flavus Aspergillus flavus MIC 250.0 ug.mL-1 10.1016/j.bmc.2008.07.079
Aspergillus fumigatus Aspergillus fumigatus MIC 250.0 ug.mL-1 10.1016/j.bmc.2008.07.079
Aspergillus niger Aspergillus niger MIC 250.0 ug.mL-1 10.1016/j.bmc.2008.07.079
Candida albicans Candida albicans Inhibition 0.0 % 10.1016/j.bmc.2008.07.079
Candida albicans Candida albicans MIC 250.0 ug.mL-1 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 0.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 4.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 5.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 7.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 10.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 12.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 13.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 14.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 15.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 17.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 21.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 22.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 29.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 32.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 33.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 34.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 35.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 45.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 46.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 47.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 50.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 54.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 67.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 74.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 76.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 77.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 83.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 84.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 87.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 88.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 99.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans Inhibition 100.0 % 10.1016/j.bmc.2008.07.079
Cryptococcus neoformans Cryptococcus neoformans MIC 31.2 ug.mL-1 10.1016/j.bmc.2008.07.079
Homo sapiens Breast cancer type 1 susceptibility protein Potency 11220.2 nM None
Homo sapiens Chromobox protein homolog 1 Potency 79432.8 nM None
Homo sapiens Lysine-specific demethylase 4A Potency 50118.7 nM None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 12589.3 nM None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 20596.2 nM None
Homo sapiens Parathyroid hormone receptor Potency 11220.2 nM None
Human T-cell leukemia virus type I Human T-cell leukemia virus type I Inhibition 0.0 % 10.1016/s0960-894x(02)01085-5
Leishmania braziliensis Leishmania braziliensis IC90 100.0 ug.mL-1 10.1021/np50099a013
Mucor circinelloides Mucor circinelloides Activity 98.1 % 10.1016/j.bmcl.2022.128649
Mucor circinelloides Mucor circinelloides Activity 98.2 % 10.1016/j.bmcl.2022.128649
Nannizzia gypsea Nannizzia gypsea MIC 16.0 ug.mL-1 10.1016/j.bmc.2008.07.079
Rattus norvegicus Glutamate NMDA receptor Ki 35000.0 nM 10.1016/s0960-894x(02)00470-5
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 125.0 ug.mL-1 10.1016/j.bmc.2008.07.079
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 25.0 ug.mL-1 10.1016/j.bmc.2008.07.079
Trichophyton rubrum Trichophyton rubrum MIC 25.0 ug.mL-1 10.1016/j.bmc.2008.07.079
Trypanosoma cruzi Trypanosoma cruzi IC90 100.0 ug.mL-1 10.1021/np50099a013
None No relevant target LogD7.4 4.0 None 10.6019/CHEMBL3301361
None No relevant target pKa 5.2 None 10.1016/s0960-894x(02)00470-5
None Unchecked Kd 1000000.0 nM 10.1016/j.bmcl.2010.11.110
None Unchecked Potency 3548.1 nM None

Metabolism Information