Isariotin D
AlkaPlorer ID: AK045993
Synonym: None
IUPAC Name: (E)-N-[(1S,2S,4S,5S,6S,7R,8S)-1,5,7-trihydroxy-10-oxo-3-oxatricyclo[4.3.1.02,4]decan-8-yl]dec-2-enamide
Structure
SMILES: CCCCCCC/C=C/C(O)=N[C@H]1C[C@@]2(O)C(=O)[C@H]([C@H](O)[C@@H]3O[C@@H]32)[C@H]1O
InChI: InChI=1S/C19H29NO6/c1-2-3-4-5-6-7-8-9-12(21)20-11-10-19(25)17(24)13(14(11)22)15(23)16-18(19)26-16/h8-9,11,13-16,18,22-23,25H,2-7,10H2,1H3,(H,20,21)/b9-8+/t11-,13-,14-,15-,16-,18-,19+/m0/s1
InChIKey: RPNMQCNKXLDNIP-NONCFBCESA-N
Reference
Isariotins A–D, Alkaloids from the Insect Pathogenic Fungus <i>Isaria tenuipes</i> BCC 7831
PubChem CID: 44445763
LOTUS: LTS0052054
NPASS: NPC471471
{NPAtlas: NPA005319
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Isaria | Cordycipitaceae | Hypocreales | Sordariomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 367.442
TPSA？: 122.88000000000002
MolLogP？: 1.0511
Number of H-Donors: 4
Number of H-Acceptors: 6
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Candida albicans | Candida albicans | Activity | nan | None | 10.1021/np070291q |
| Chlorocebus sabaeus | Vero | Activity | nan | None | 10.1021/np070291q |
| Homo sapiens | KB | Activity | nan | None | 10.1021/np070291q |
| Homo sapiens | NCI-H187 | Activity | nan | None | 10.1021/np070291q |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC | 544000.0 | nM | 10.1021/np070291q |
| Plasmodium falciparum | Plasmodium falciparum | Activity | nan | None | 10.1021/np070291q |
| Pyricularia grisea | Pyricularia grisea | Activity | nan | None | 10.1021/np070291q |
| None | NON-PROTEIN TARGET | Activity | nan | None | 10.1021/np070291q |