6,7-dibromo-4-oxo-1,4-dihydroquinoline-2-carboxylic acid
AlkaPlorer ID: AK046152
Synonym: None
IUPAC Name: 6,7-dibromo-4-oxo-1H-quinoline-2-carboxylic acid
Structure
SMILES: O=C(O)C1=CC(=O)C2=CC(Br)=C(Br)C=C2N1
InChI: InChI=1S/C10H5Br2NO3/c11-5-1-4-7(2-6(5)12)13-8(10(15)16)3-9(4)14/h1-3H,(H,13,14)(H,15,16)
InChIKey: WHRFFBWANBDQJV-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 346.962
TPSA？: 70.16
MolLogP？: 2.7513000000000005
Number of H-Donors: 2
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Candida albicans | Candida albicans | Activity | nan | None | 10.1021/np100329w |
| Enterococcus faecalis | Enterococcus faecalis | Activity | nan | None | 10.1021/np100329w |
| Escherichia coli | Escherichia coli | Activity | nan | None | 10.1021/np100329w |
| Homo sapiens | MCF7 | Inhibition | 49.0 | % | 10.1021/np100329w |
| Homo sapiens | MM96L | Inhibition | 69.0 | % | 10.1021/np100329w |
| Homo sapiens | NFF | Inhibition | 66.0 | % | 10.1021/np100329w |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | Activity | nan | None | 10.1021/np100329w |
| Staphylococcus aureus | Staphylococcus aureus | Activity | nan | None | 10.1021/np100329w |