1,2,3,4,6,7,8,9-octahydrophenazine
AlkaPlorer ID: AK046492
Synonym: 'SMR000528198', 'MLS000737867'
IUPAC Name: 1,2,3,4,6,7,8,9-octahydrophenazine
Structure
SMILES: C1CCC2=NC3=C(CCCC3)N=C2C1
InChI: InChI=1S/C12H16N2/c1-2-6-10-9(5-1)13-11-7-3-4-8-12(11)14-10/h1-8H2
InChIKey: JYYRTWNCBVRKMN-UHFFFAOYSA-N
Reference
Two phenazine derivatives, polycartine A and B from idesiapolycarpa maxim (flacourtiaceae)
PubChem CID: 77623
CAS: 4006-50-2
LOTUS: LTS0150518
SuperNatural Ⅲ: SN0179116
COCONUT: CNP0191835
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Idesia polycarpa | Idesia | Salicaceae | Malpighiales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 188.274
TPSA？: 25.78
MolLogP？: 2.2342000000000004
Number of H-Donors: 0
Number of H-Acceptors: 2
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Acinetobacter baumannii | Acinetobacter baumannii | Inhibition | -4.6 | % | 10.6019/CHEMBL4296182 |
| Candida albicans | Candida albicans | Inhibition | 1.61 | % | 10.6019/CHEMBL4296182 |
| Cryptococcus neoformans | Cryptococcus neoformans | Inhibition | -2.79 | % | 10.6019/CHEMBL4296182 |
| Escherichia coli | Escherichia coli | Inhibition | 11.61 | % | 10.6019/CHEMBL4296182 |
| Homo sapiens | DNA-(apurinic or apyrimidinic site) lyase | Potency | 2511.9 | nM | None |
| Klebsiella pneumoniae | Klebsiella pneumoniae | Inhibition | 13.7 | % | 10.6019/CHEMBL4296182 |
| Macaca fascicularis | T-complex protein 1 subunit beta | Potency | 12589.3 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 13115.4 | nM | None |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | Inhibition | 19.99 | % | 10.6019/CHEMBL4296182 |
| Staphylococcus aureus | Staphylococcus aureus | Inhibition | 13.53 | % | 10.6019/CHEMBL4296182 |