Clausine M
AlkaPlorer ID: AK047078
Synonym: None
IUPAC Name: methyl 7-hydroxy-9H-carbazole-3-carboxylate
Structure
SMILES: COC(=O)C1=CC=C2NC3=CC(O)=CC=C3C2=C1
InChI: InChI=1S/C14H11NO3/c1-18-14(17)8-2-5-12-11(6-8)10-4-3-9(16)7-13(10)15-12/h2-7,15-16H,1H3
InChIKey: DLSYIZRGLJIEKT-UHFFFAOYSA-N
Reference
Alkaloidal and other constituents from the root bark of Clausena excavata
PubChem CID: 15550280
CAS: 250259-33-7
LOTUS: LTS0132750
COCONUT: CNP0147980
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Clausena excavata | Clausena | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 241.246
TPSA？: 62.32000000000001
MolLogP？: 2.813300000000001
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Chlorocebus sabaeus | Vero | IC50 | 35000.0 | nM | 10.1007/s00044-007-9073-0 |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC90 | 19000.0 | nM | 10.1007/s00044-007-9073-0 |
| None | Unchecked | Selectivity Index | 1.8 | None | 10.1007/s00044-007-9073-0 |