Limazepine A
AlkaPlorer ID: AK047665
Synonym: None
IUPAC Name: (6aS)-8-ethyl-4-hydroxy-3-methoxy-6a,7-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-6,11-dione
Structure
SMILES: CCC1=CN2C(=O)C3=CC=C(OC)C(O)=C3N=C(O)[C@@H]2C1
InChI: InChI=1S/C15H16N2O4/c1-3-8-6-10-14(19)16-12-9(15(20)17(10)7-8)4-5-11(21-2)13(12)18/h4-5,7,10,18H,3,6H2,1-2H3,(H,16,19)/t10-/m0/s1
InChIKey: WFFPORSPDSBCLL-JTQLQIEISA-N
Reference
Limazepines A−F, Pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian <i>Micrococcus</i> sp.
PubChem CID: 42639334
LOTUS: LTS0257991
SuperNatural Ⅲ: SN0408650-01
NPASS: NPC191446
{NPAtlas: NPA007410
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Micrococcus sp. | Micrococcus | Micrococcaceae | Micrococcales | Actinomycetes | Actinomycetota | None | Bacteria |
| None | Micrococcus | Micrococcaceae | Micrococcales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 288.303
TPSA？: 82.36
MolLogP？: 2.5108000000000006
Number of H-Donors: 2
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | Activity | None | None | 10.1021/np800827w |
| Candida albicans | Candida albicans | Activity | None | None | 10.1021/np800827w |
| Escherichia coli | Escherichia coli | IZ | None | None | 10.1021/np800827w |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | IZ | None | None | 10.1021/np800827w |
| Rhizomucor miehei | Rhizomucor miehei | Activity | None | None | 10.1021/np800827w |
| Staphylococcus aureus | Staphylococcus aureus | IZ | None | None | 10.1021/np800827w |