2-Amino-3H-phenoxazin-3-one; 9-Hydroxy, N-Ac
AlkaPlorer ID: AK048427
Synonym: N-Acetyl-9-hydroxyquestiomycin A, Chandrananimycin A
IUPAC Name: N-(9-hydroxy-3-oxophenoxazin-2-yl)acetamide
Structure
SMILES: CC(=O)NC1=CC2=NC3=C(O)C=CC=C3OC2=CC1=O
InChI: InChI=1S/C14H10N2O4/c1-7(17)15-8-5-9-13(6-11(8)19)20-12-4-2-3-10(18)14(12)16-9/h2-6,18H,1H3,(H,15,17)
InChIKey: VRKDUDPRCAZBHW-UHFFFAOYSA-N
Reference
PubChem CID: 9993261
CAS: 664355-12-8
LOTUS: LTS0047610
COCONUT: CNP0073925
{NPAtlas: NPA020148
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Actinomadura sp. | Actinomadura | Thermomonosporaceae | Streptosporangiales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 270.244
TPSA？: 92.43
MolLogP？: 1.9568
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Indoleamine 2,3-dioxygenase | Inhibition | 92.0 | % | 10.1021/jm400049z |
| Homo sapiens | Indoleamine 2,3-dioxygenase | Inhibition | 99.0 | % | 10.1021/jm400049z |
| Homo sapiens | Indoleamine 2,3-dioxygenase | Inhibition | 100.0 | % | 10.1021/jm400049z |