Cyfusine
AlkaPlorer ID: AK048537
Synonym: None
IUPAC Name: 1,2,3,3a,4,9b-hexahydropyrrolo[3,4-a]indolizin-6-one
Structure
SMILES: O=C1C=CC=C2C3CNCC3CN21
InChI: InChI=1S/C10H12N2O/c13-10-3-1-2-9-8-5-11-4-7(8)6-12(9)10/h1-3,7-8,11H,4-6H2
InChIKey: CXOGMMQKRNROKJ-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Dendrobium chrysanthum | Dendrobium | Orchidaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 176.219
TPSA？: 34.03
MolLogP？: 0.1648999999999998
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Neuronal acetylcholine receptor; alpha3/beta4 | Ki | 500.0 | nM | 10.1016/j.bmcl.2008.02.078 |
| Rattus norvegicus | Neuronal acetylcholine receptor; alpha4/beta2 | Ki | 16.0 | nM | 10.1016/j.bmcl.2008.02.078 |
| Rattus norvegicus | Neuronal acetylcholine receptor protein alpha-7 subunit | Ki | 500.0 | nM | 10.1016/j.bmcl.2008.02.078 |