2-[(Carboxymethyl)amino]benzoic acid
AlkaPlorer ID: AK048924
Synonym: N-(2-Carboxyphenyl)glycine, N-(Carboxymethyl)anthranilic acid
IUPAC Name: 2-(carboxymethylamino)benzoic acid
Structure
SMILES: O=C(O)CNC1=CC=CC=C1C(=O)O
InChI: InChI=1S/C9H9NO4/c11-8(12)5-10-7-4-2-1-3-6(7)9(13)14/h1-4,10H,5H2,(H,11,12)(H,13,14)
InChIKey: PJUXPMVQAZLJEX-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus | Bacillaceae | Bacillales | Bacilli | Bacillota | None | Bacteria |
Properties Information
Molecule Weight: 195.174
TPSA？: 86.63000000000001
MolLogP？: 0.8813000000000002
Number of H-Donors: 3
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | MIC | 64.0 | ug.mL-1 | 10.1021/np400589h |
| Enterococcus faecalis | Enterococcus faecalis | MIC | 64.0 | ug.mL-1 | 10.1021/np400589h |
| Escherichia coli | Escherichia coli | MIC | 64.0 | ug.mL-1 | 10.1021/np400589h |
| Homo sapiens | ATPase family AAA domain-containing protein 5 | Potency | 20587.8 | nM | None |
| Homo sapiens | Bromodomain adjacent to zinc finger domain protein 2B | Potency | 89125.1 | nM | None |
| Homo sapiens | DNA polymerase eta | Potency | 19952.6 | nM | None |
| Homo sapiens | DNA polymerase eta | Potency | 60119.8 | nM | None |
| Homo sapiens | DNA polymerase iota | Potency | 44668.4 | nM | None |
| Homo sapiens | Geminin | Potency | 16360.1 | nM | None |
| Homo sapiens | Lethal(3)malignant brain tumor-like protein 1 | Potency | 2993.5 | nM | None |
| Homo sapiens | Lethal(3)malignant brain tumor-like protein 1 | Potency | 22387.2 | nM | None |
| Homo sapiens | Lysine-specific demethylase 4A | Potency | 56234.1 | nM | None |
| Homo sapiens | Lysine-specific demethylase 4D-like | Potency | 28183.8 | nM | None |
| Homo sapiens | Lysosomal alpha-glucosidase | Potency | 12589.3 | nM | None |
| Homo sapiens | Sphingomyelin phosphodiesterase | Potency | 25118.9 | nM | None |
| Homo sapiens | Transcriptional regulator ERG | Potency | 50118.7 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 8275.3 | nM | None |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | MIC | 64.0 | ug.mL-1 | 10.1021/np400589h |
| Rattus norvegicus | Glutamate NMDA receptor | IC50 | 4000.0 | nM | 10.1021/jm00086a005 |
| Rattus norvegicus | Rattus norvegicus | IC50 | 250000.0 | nM | 10.1021/jm00086a005 |
| Rattus norvegicus | Thioredoxin reductase 1, cytoplasmic | Potency | 79432.8 | nM | None |
| Saccharomyces cerevisiae S288c | CAAX prenyl protease 2 | AC50 | 11320.0 | nM | None |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 64.0 | ug.mL-1 | 10.1021/np400589h |
| Streptococcus pneumoniae | Streptococcus pneumoniae | MIC | 64.0 | ug.mL-1 | 10.1021/np400589h |