4-ethoxy-7,8-dimethoxyfuro[2,3-b]quinoline
AlkaPlorer ID: AK049172
Synonym: 'MLS001048848', 'SMR000387057'
IUPAC Name: 4-ethoxy-7,8-dimethoxyfuro[2,3-b]quinoline
Structure
SMILES: CCOC1=C2C=COC2=NC2=C(OC)C(OC)=CC=C12
InChI: InChI=1S/C15H15NO4/c1-4-19-13-9-5-6-11(17-2)14(18-3)12(9)16-15-10(13)7-8-20-15/h5-8H,4H2,1-3H3
InChIKey: QSGZRSBPMIEJQQ-UHFFFAOYSA-N
Reference
Constituents of the root of Dictamnus albus L.
PubChem CID: 8016789
CAS: 106006-02-4
LOTUS: LTS0116251
SuperNatural Ⅲ: SN0082786
COCONUT: CNP0155689
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Dictamnus albus | Dictamnus | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 273.28799999999995
TPSA？: 53.72000000000001
MolLogP？: 3.3969000000000014
Number of H-Donors: 0
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Aldehyde dehydrogenase 1A1 | Potency | 35481.3 | nM | None |
| Homo sapiens | ATPase family AAA domain-containing protein 5 | Potency | 20587.8 | nM | None |
| Homo sapiens | DNA-(apurinic or apyrimidinic site) lyase | Potency | 7943.3 | nM | None |
| Homo sapiens | HepG2 | Potency | 25118.9 | nM | None |
| Homo sapiens | Isocitrate dehydrogenase [NADP] cytoplasmic | Potency | 18356.4 | nM | None |
| Homo sapiens | Lysine-specific demethylase 4D-like | Potency | 28183.8 | nM | None |
| Homo sapiens | Menin/Histone-lysine N-methyltransferase MLL | Potency | 11220.2 | nM | None |
| Homo sapiens | microRNA 21 | Potency | 13091.8 | nM | None |
| Homo sapiens | Microtubule-associated protein tau | Potency | 794.3 | nM | None |
| Homo sapiens | Muscleblind-like protein 1 | Potency | 28183.8 | nM | None |
| Homo sapiens | Parathyroid hormone receptor | Potency | 17782.8 | nM | None |
| Influenza A virus | Nonstructural protein 1 | Potency | 10000.0 | nM | None |
| Photinus pyralis | Luciferin 4-monooxygenase | Potency | 21331.3 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 928.5 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 18526.0 | nM | None |
| Rattus norvegicus | Thioredoxin reductase 1, cytoplasmic | Potency | 19952.6 | nM | None |
| None | Unchecked | Potency | 2818.4 | nM | None |
| None | Unchecked | Potency | 7079.5 | nM | None |
| None | Unchecked | Potency | 15848.9 | nM | None |
| None | Unchecked | Potency | 28183.8 | nM | None |