6-methyl-1,6-diazatetracyclo[7.6.1.0⁵,¹⁶.0¹⁰,¹⁵]hexadeca-3,5(16),8,10,12,14-hexaene-2,7-dione
AlkaPlorer ID: AK049656
Synonym: None
IUPAC Name: 6-methyl-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-3,5(16),8,10,12,14-hexaene-2,7-dione
Structure
SMILES: CN1C(=O)C=C2C3=CC=CC=C3N3C(=O)C=CC1=C23
InChI: InChI=1S/C15H10N2O2/c1-16-12-6-7-13(18)17-11-5-3-2-4-9(11)10(15(12)17)8-14(16)19/h2-8H,1H3
InChIKey: OSQVNYBFJBIHGZ-UHFFFAOYSA-N
Reference
Studies on the constituents of Picrasma quassioides Bennet. I. On the alkaloidal constituents.
PubChem CID: 606442
LOTUS: LTS0202589
SuperNatural Ⅲ: SN0274242
COCONUT: CNP0199286
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Picrasma quassioides | Picrasma | Simaroubaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 250.257
TPSA？: 43.48
MolLogP？: 1.7423999999999995
Number of H-Donors: 0
Number of H-Acceptors: 4
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Protein-tyrosine phosphatase 1B | Inhibition | 33.6 | % | 10.1016/j.bmcl.2015.03.014 |
| Meriones unguiculatus | Meriones unguiculatus | Activity | 10.6 | % | 10.1016/j.bmcl.2016.09.006 |
| Meriones unguiculatus | Meriones unguiculatus | Activity | 40.0 | % | 10.1016/j.bmcl.2016.09.006 |