8-Hydroxyeupolauridine
AlkaPlorer ID: AK049798
Synonym: 'Indeno1,2,3-ij2,7naphthyridin-8-ol', '8-hydroxyeupolauridine'
IUPAC Name: 2,8-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-1,3,5(16),6,8,10(15),11,13-octaen-12-ol
Structure
SMILES: OC1=CC=C2C(=C1)C1=NC=CC3=CC=NC2=C13
InChI: InChI=1S/C14H8N2O/c17-9-1-2-10-11(7-9)14-12-8(4-6-16-14)3-5-15-13(10)12/h1-7,17H
InChIKey: CTGUKNNRGTZRCB-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Ambavia gerrardii | Ambavia | Annonaceae | Magnoliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 220.231
TPSA？: 46.010000000000005
MolLogP？: 2.982800000000001
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A2780 | IC50 | 12700.0 | nM | 10.1021/np200093n |
| Homo sapiens | NCI-H460 | IC50 | 10000.0 | nM | 10.1021/np200093n |