Huperzine C
AlkaPlorer ID: AK051659
Synonym: ''
IUPAC Name: (1R,9R,13R)-1-amino-13-ethenyl-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one
Structure
SMILES: C=C[C@@H]1[C@H]2C=C(C)C[C@]1(N)C1=C(C2)NC(=O)C=C1
InChI: InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10-11H,1,7-8,16H2,2H3,(H,17,18)/t10-,11+,15+/m0/s1
InChIKey: IZGRHSRWTILCID-FIXISWKDSA-N
Reference
Lycoparins A–C, new alkaloids from Lycopodium casuarinoides inhibiting acetylcholinesterase
PubChem CID: 10198698
LOTUS: LTS0125496
NPASS: NPC32028
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Lycopodiastrum casuarinoides | Lycopodiastrum | Lycopodiaceae | Lycopodiales | Lycopodiopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 242.322
TPSA？: 58.88
MolLogP？: 1.8534
Number of H-Donors: 2
Number of H-Acceptors: 2
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Acetylcholinesterase | IC50 | 489.0 | nM | 10.1021/np4003355 |
| Rattus norvegicus | Acetylcholinesterase | Inhibition | nan | % | 10.1021/np4003355 |