Molecule

Corlumine

AlkaPlorer ID: AK052130

Synonym: None

IUPAC Name: (6S)-6-[(1S)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one

Structure

SMILES: COC1=C(OC)C=C2C(=C1)CCN(C)[C@@H]2[C@H]1OC(=O)C2=C3OCOC3=CC=C21

InChI: InChI=1S/C21H21NO6/c1-22-7-6-11-8-15(24-2)16(25-3)9-13(11)18(22)19-12-4-5-14-20(27-10-26-14)17(12)21(23)28-19/h4-5,8-9,18-19H,6-7,10H2,1-3H3/t18-,19-/m0/s1

InChIKey: SZDGAZFTAUFFQH-OALUTQOASA-N

Reference

Alkaloids from Fumaria judaica

PubChem CID: 442155

CAS: 524-46-9

LOTUS: LTS0045181

SuperNatural Ⅲ: SN0359224-02

NPASS: NPC46744

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Ulex airensis	Ulex	Fabaceae	Fabales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Stachys plumosa	Stachys	Lamiaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Corydalis decumbens	Corydalis	Papaveraceae	Ranunculales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Piper methysticum	Piper	Piperaceae	Piperales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Artabotrys maingayi	Artabotrys	Annonaceae	Magnoliales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Diospyros ebenum	Diospyros	Ebenaceae	Ericales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Ligularia sagitta	Ligularia	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Angelica dahurica	Angelica	Apiaceae	Apiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Lappula echinata	Lappula	Boraginaceae	Boraginales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Corydalis ophiocarpa	Corydalis	Papaveraceae	Ranunculales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Corydalis scouleri	Corydalis	Papaveraceae	Ranunculales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Thuja plicata	Thuja	Cupressaceae	Cupressales	Pinopsida	Streptophyta	Viridiplantae	Eukaryota
Corydalis ternata	Corydalis	Papaveraceae	Ranunculales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Stereocaulon alpinum	Stereocaulon	Stereocaulaceae	Lecanorales	Lecanoromycetes	Ascomycota	Fungi	Eukaryota
Labidiaster annulatus	Labidiaster	Labidiasteridae	Forcipulatida	Asteroidea	Echinodermata	Metazoa	Eukaryota
Senna spectabilis	Senna	Fabaceae	Fabales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Chaetomorpha moniligera	Chaetomorpha	Cladophoraceae	Cladophorales	Ulvophyceae	Chlorophyta	Viridiplantae	Eukaryota
Lasius niger	Lasius	Formicidae	Hymenoptera	Insecta	Arthropoda	Metazoa	Eukaryota
Streptomyces aizunensis	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria
Symphytum officinale	Symphytum	Boraginaceae	Boraginales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Dictyostelium longosporum	Dictyostelium	Dictyosteliaceae	Dictyosteliales	Eumycetozoa	Evosea	None	Eukaryota
Capnoides sempervirens	Capnoides	Papaveraceae	Ranunculales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Psacalium peltatum	Psacalium	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 383.40000000000015

TPSA？: 66.46000000000001

MolLogP？: 2.873200000000001

Number of H-Donors: 0

Number of H-Acceptors: 7

RingCount: 5

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Cavia porcellus	Ileum	Activity	0.0	%	10.1021/np50028a006
Cavia porcellus	Ileum	Activity	50.0	%	10.1021/np50028a006
Cavia porcellus	Ileum	Activity	nan	None	10.1021/np50028a006
Cavia porcellus	Ileum	IC50	0.5	ug.mL-1	10.1021/np50027a004
Cavia porcellus	Ileum	IC50	0.5	ug.mL-1	10.1021/np50028a006
Cavia porcellus	Ileum	Inhibition	0.0	%	10.1021/np50027a004
Cavia porcellus	Ileum	Inhibition	50.0	%	10.1021/np50027a004