6H,7H,8H,9H-pyrido[2,1-b]quinazolin-11-one
AlkaPlorer ID: AK053774
Synonym: None
IUPAC Name: 6,7,8,9-tetrahydropyrido[2,1-b]quinazolin-11-one
Structure
SMILES: O=C1C2=CC=CC=C2N=C2CCCCN21
InChI: InChI=1S/C12H12N2O/c15-12-9-5-1-2-6-10(9)13-11-7-3-4-8-14(11)12/h1-2,5-6H,3-4,7-8H2
InChIKey: LMDWOGWJYVSXEP-UHFFFAOYSA-N
Reference
6,7,8,9-Tetrahydropyridoquinazolines, a new class of alkaloids from Mackinlaya species (Araliaceae)
PubChem CID: 523975
CAS: 2446-62-0
LOTUS: LTS0100318
SuperNatural Ⅲ: SN0209333
COCONUT: CNP0224026
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Mackinlaya schlechteri | Mackinlaya | Apiaceae | Apiales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 200.241
TPSA？: 34.89
MolLogP？: 1.7328
Number of H-Donors: 0
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Cavia porcellus | Tissue | Activity | 40.0 | % | 10.1007/s00044-006-0141-7 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | IC50 | 19952.62 | nM | 10.6019/CHEMBL4651402 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | IC50 | 20000.0 | nM | 10.6019/CHEMBL4651402 |