Phaitanthrin C
AlkaPlorer ID: AK055628
Synonym: None
IUPAC Name: 7-hydroxyindolo[2,1-b]quinazoline-6,12-dione
Structure
SMILES: O=C1C2=C(C=CC=C2O)N2C1=NC1=CC=CC=C1C2=O
InChI: InChI=1S/C15H8N2O3/c18-11-7-3-6-10-12(11)13(19)14-16-9-5-2-1-4-8(9)15(20)17(10)14/h1-7,18H
InChIKey: WOQXYBJCORZEEE-UHFFFAOYSA-N
Reference
PubChem CID: 24970644
CAS: 1033722-04-1
LOTUS: LTS0214901
SuperNatural Ⅲ: SN0415877
COCONUT: CNP0153714
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Phaius mishmensis | Phaius | Orchidaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 264.23999999999995
TPSA？: 72.19
MolLogP？: 1.6357
Number of H-Donors: 1
Number of H-Acceptors: 5
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | MCF7 | IC50 | 50000.0 | nM | 10.1021/np800064w |
| Homo sapiens | NCI-H460 | IC50 | 50000.0 | nM | 10.1021/np800064w |
| Homo sapiens | SF-268 | IC50 | 50000.0 | nM | 10.1021/np800064w |