Navigation

name Structure Reference Source Properties Activities Metabolism

Fumiquinazoline S

AlkaPlorer ID: AK057548

Synonym: None

IUPAC Name: (1S,4R)-4-[[(2S,3aR,4R)-4-hydroxy-1-oxo-2-propan-2-yl-3,3a-dihydro-2H-imidazo[1,2-a]indol-4-yl]methyl]-1-methyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-dione

Structure

SMILES: CC(C)[C@@H]1N[C@@H]2N(C1=O)C1=CC=CC=C1[C@]2(O)C[C@@H]1C(O)=N[C@@H](C)C2=NC3=CC=CC=C3C(=O)N21

copy

InChI: InChI=1S/C26H27N5O4/c1-13(2)20-24(34)31-18-11-7-5-9-16(18)26(35,25(31)29-20)12-19-22(32)27-14(3)21-28-17-10-6-4-8-15(17)23(33)30(19)21/h4-11,13-14,19-20,25,29,35H,12H2,1-3H3,(H,27,32)/t14-,19+,20-,25+,26+/m0/s1

copy

InChIKey: JNCNRIDYWQJICU-IACIIXEISA-N

copy

Source

Species Genus Family Order Class Phylum Kingdom Domain
Aspergillus sp. Aspergillus Aspergillaceae Eurotiales Eurotiomycetes Ascomycota Fungi Eukaryota

Properties Information

Molecule Weight: 473.5330000000002

TPSA？: 120.05

MolLogP？: 2.5471000000000004

Number of H-Donors: 3

Number of H-Acceptors: 7

RingCount: 6

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus subtilis Bacillus subtilis MIC 100.0 ug.mL-1 10.1021/np500683u
Candida albicans Isocitrate lyase Inhibition nan % 10.1021/np500683u
Escherichia coli Escherichia coli MIC 100.0 ug.mL-1 10.1021/np500683u
Homo sapiens A549 IC50 15780.0 nM 10.1021/np500683u
Homo sapiens K562 IC50 13840.0 nM 10.1021/np500683u
Micrococcus luteus Micrococcus luteus MIC 100.0 ug.mL-1 10.1021/np500683u
Proteus hauseri Proteus hauseri MIC 100.0 ug.mL-1 10.1021/np500683u
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 100.0 ug.mL-1 10.1021/np500683u
Staphylococcus aureus Staphylococcus aureus MIC 100.0 ug.mL-1 10.1021/np500683u
None Unchecked IC50 34280.0 nM 10.1021/np500683u
None Unchecked Inhibition nan % 10.1021/np500683u

Metabolism Information