Xenortide B
AlkaPlorer ID: AK059156
Synonym: None
IUPAC Name: (2S)-N-[(2S)-1-[2-(1H-indol-3-yl)ethylamino]-1-oxo-3-phenylpropan-2-yl]-N,4-dimethyl-2-(methylamino)pentanamide
Structure
SMILES: CN[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC1=CC=CC=C1)C(=O)NCCC1=CNC2=CC=CC=C12
InChI: InChI=1S/C27H36N4O2/c1-19(2)16-24(28-3)27(33)31(4)25(17-20-10-6-5-7-11-20)26(32)29-15-14-21-18-30-23-13-9-8-12-22(21)23/h5-13,18-19,24-25,28,30H,14-17H2,1-4H3,(H,29,32)/t24-,25-/m0/s1
InChIKey: SOIIKURIVIWMKK-DQEYMECFSA-N
Reference
Linear and Cyclic Peptides from the Entomopathogenic Bacterium <i>Xenorhabdus nematophilus</i>
PubChem CID: 24900169
NPASS: NPC94752
{NPAtlas: NPA018977
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Xenorhabdus nematophila | Xenorhabdus | Morganellaceae | Enterobacterales | Gammaproteobacteria | Pseudomonadota | None | Bacteria |
| None | Xenorhabdus | Morganellaceae | Enterobacterales | Gammaproteobacteria | Pseudomonadota | None | Bacteria |
Properties Information
Molecule Weight: 448.6110000000002
TPSA？: 77.23
MolLogP？: 3.530400000000001
Number of H-Donors: 3
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Artemia salina | Artemia salina | IC50 | 200.0 | ug.mL-1 | 10.1021/np800053n |
| Bacillus subtilis | Bacillus subtilis | Activity | nan | None | 10.1021/np800053n |
| Erwinia amylovora | Erwinia amylovora | Activity | nan | None | 10.1021/np800053n |
| Escherichia coli | Escherichia coli | Activity | nan | None | 10.1021/np800053n |
| Leishmania donovani | Leishmania donovani | IC50 | 111200.0 | nM | 10.1021/np500390b |
| Mammaliicoccus lentus | Mammaliicoccus lentus | Activity | nan | None | 10.1021/np800053n |
| Nakaseomyces glabratus | Nakaseomyces glabratus | Activity | nan | None | 10.1021/np800053n |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 760.0 | nM | 10.1021/np500390b |
| Pseudomonas fluorescens | Pseudomonas fluorescens | Activity | nan | None | 10.1021/np800053n |
| Pseudomonas syringae | Pseudomonas syringae | Activity | nan | None | 10.1021/np800053n |
| Ralstonia solanacearum | Ralstonia solanacearum | Activity | nan | None | 10.1021/np800053n |
| Rattus norvegicus | L6 | IC50 | 13690.0 | nM | 10.1021/np500390b |
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | IC50 | 1570.0 | nM | 10.1021/np500390b |
| Trypanosoma cruzi | Trypanosoma cruzi | IC50 | 11700.0 | nM | 10.1021/np500390b |
| Xanthomonas campestris | Xanthomonas campestris | Activity | nan | None | 10.1021/np800053n |