Limazepine C
AlkaPlorer ID: AK061118
Synonym: None
IUPAC Name: (6aS)-8-ethyl-4-hydroxy-3-methoxy-6a,7-dihydropyrrolo[2,1-c][1,4]benzodiazepin-11-one
Structure
SMILES: CCC1=CN2C(=O)C3=C(N=C[C@@H]2C1)C(O)=C(OC)C=C3
InChI: InChI=1S/C15H16N2O3/c1-3-9-6-10-7-16-13-11(15(19)17(10)8-9)4-5-12(20-2)14(13)18/h4-5,7-8,10,18H,3,6H2,1-2H3/t10-/m0/s1
InChIKey: FLGURYUVNVBBFP-JTQLQIEISA-N
Reference
Limazepines A−F, Pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian <i>Micrococcus</i> sp.
PubChem CID: 42639506
LOTUS: LTS0014113
SuperNatural Ⅲ: SN0088763-01
NPASS: NPC158551
{NPAtlas: NPA016210
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Micrococcus sp. | Micrococcus | Micrococcaceae | Micrococcales | Actinomycetes | Actinomycetota | None | Bacteria |
| None | Micrococcus | Micrococcaceae | Micrococcales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 272.304
TPSA？: 62.13000000000001
MolLogP？: 2.6251000000000007
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | Activity | nan | None | 10.1021/np800827w |
| Candida albicans | Candida albicans | Activity | nan | None | 10.1021/np800827w |
| Escherichia coli | Escherichia coli | IZ | 10.0 | mm | 10.1021/np800827w |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | IZ | nan | None | 10.1021/np800827w |
| Rhizomucor miehei | Rhizomucor miehei | Activity | nan | None | 10.1021/np800827w |
| Staphylococcus aureus | Staphylococcus aureus | IZ | 18.0 | mm | 10.1021/np800827w |