Molecule

Salinosporamide J

AlkaPlorer ID: AK063483

Synonym: '', 'Salinosporamide J'

IUPAC Name: (1R,4R,5S)-4-(2-chloroethyl)-1-[[(1R)-cyclohex-2-en-1-yl]methyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione

Structure

SMILES: C[C@@]12OC(=O)[C@]1(C[C@@H]1C=CCCC1)N=C(O)[C@@H]2CCCl

InChI: InChI=1S/C15H20ClNO3/c1-14-11(7-8-16)12(18)17-15(14,13(19)20-14)9-10-5-3-2-4-6-10/h3,5,10-11H,2,4,6-9H2,1H3,(H,17,18)/t10-,11+,14+,15+/m1/s1

InChIKey: URJGVVMJOFUXRZ-PKIAMQTDSA-N

Reference

Salinosporamides D−J from the Marine Actinomycete <i>Salinispora tropica</i>, Bromosalinosporamide, and Thioester Derivatives Are Potent Inhibitors of the 20S Proteasome

PubChem CID: 22833283

LOTUS: LTS0136751

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Salinispora tropica	Salinispora	Micromonosporaceae	Micromonosporales	Actinomycetes	Actinomycetota	None	Bacteria

Properties Information

Molecule Weight: 297.7819999999999

TPSA？: 58.89

MolLogP？: 3.002300000000001

Number of H-Donors: 1

Number of H-Acceptors: 3

RingCount: 3

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi