Tyrostatin
AlkaPlorer ID: AK063992
Synonym: None
IUPAC Name: (2S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-(3-methylbutanoylamino)propanoyl]amino]-N-[(2S)-1-(4-hydroxyphenyl)-3-oxopropan-2-yl]-4-methylpentanamide
Structure
SMILES: CC(C)CC(O)=N[C@@H](CC1=CC=C(O)C=C1)C(O)=N[C@@H](CC(C)C)C(O)=N[C@H](C=O)CC1=CC=C(O)C=C1
InChI: InChI=1S/C29H39N3O6/c1-18(2)13-25(28(37)30-22(17-33)15-20-5-9-23(34)10-6-20)32-29(38)26(31-27(36)14-19(3)4)16-21-7-11-24(35)12-8-21/h5-12,17-19,22,25-26,34-35H,13-16H2,1-4H3,(H,30,37)(H,31,36)(H,32,38)/t22-,25-,26-/m0/s1
InChIKey: FWNXEHQYIWGYHB-HRNNMHKYSA-N
Reference
A Novel Proteinase Inhibitor, Tyrostatin, Inhibiting Some Pepstatin-insensitive Carboxyl Proteinases
PubChem CID: 87651437
LOTUS: LTS0108062
SuperNatural Ⅲ: SN0097423-02
{NPAtlas: NPA014522
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Kitasatospora sp. | Kitasatospora | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 525.6460000000003
TPSA？: 155.3
MolLogP？: 5.149400000000005
Number of H-Donors: 5
Number of H-Acceptors: 6
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|