Limazepine E
AlkaPlorer ID: AK064625
Synonym: None
IUPAC Name: (6aS,8E)-8-ethylidene-4-hydroxy-3-methoxy-7,9-dihydro-6aH-pyrrolo[2,1-c][1,4]benzodiazepin-11-one
Structure
SMILES: C/C=C1\C[C@H]2C=NC3=C(C=CC(OC)=C3O)C(=O)N2C1
InChI: InChI=1S/C15H16N2O3/c1-3-9-6-10-7-16-13-11(15(19)17(10)8-9)4-5-12(20-2)14(13)18/h3-5,7,10,18H,6,8H2,1-2H3/b9-3+/t10-/m0/s1
InChIKey: FOMJEHKAWAOFOV-RZCNENHTSA-N
Reference
Limazepines A−F, Pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian <i>Micrococcus</i> sp.
PubChem CID: 42639507
LOTUS: LTS0092170
SuperNatural Ⅲ: SN0091254-02
NPASS: NPC163829
{NPAtlas: NPA019802
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Micrococcus sp. | Micrococcus | Micrococcaceae | Micrococcales | Actinomycetes | Actinomycetota | None | Bacteria |
| None | Micrococcus | Micrococcaceae | Micrococcales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 272.30400000000003
TPSA？: 62.13
MolLogP？: 2.2775
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | Activity | nan | None | 10.1021/np800827w |
| Candida albicans | Candida albicans | Activity | nan | None | 10.1021/np800827w |
| Escherichia coli | Escherichia coli | IZ | 10.0 | mm | 10.1021/np800827w |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | IZ | nan | None | 10.1021/np800827w |
| Rhizomucor miehei | Rhizomucor miehei | Activity | nan | None | 10.1021/np800827w |
| Staphylococcus aureus | Staphylococcus aureus | IZ | 12.0 | mm | 10.1021/np800827w |