3-methoxy-4-phenylquinolin-2-ol
AlkaPlorer ID: AK065961
Synonym: None
IUPAC Name: 3-methoxy-4-phenyl-1H-quinolin-2-one
Structure
SMILES: COC1=C(O)N=C2C=CC=CC2=C1C1=CC=CC=C1
InChI: InChI=1S/C16H13NO2/c1-19-15-14(11-7-3-2-4-8-11)12-9-5-6-10-13(12)17-16(15)18/h2-10H,1H3,(H,17,18)
InChIKey: NDTLHHOQSHJIMX-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Talaromyces verruculosus | Talaromyces | Trichocomaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 251.285
TPSA？: 42.35
MolLogP？: 3.6160000000000014
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | PBMC | Inhibition | 24.0 | % | 10.1016/j.bmcl.2007.08.036 |
| Homo sapiens | PBMC | Inhibition | 67.0 | % | 10.1016/j.bmcl.2007.08.036 |
| Homo sapiens | THP-1 | Inhibition | 7.0 | % | 10.1016/j.bmcl.2007.08.036 |
| Homo sapiens | THP-1 | Inhibition | 10.0 | % | 10.1016/j.bmcl.2007.08.036 |