Molecule

pyridine-2,3-diol

AlkaPlorer ID: AK066077

Synonym: '3-Hydroxy-2-pyridone', '2,3-Pyridinediol', '2,3-Dihydroxypyridine'

IUPAC Name: 3-hydroxy-1H-pyridin-2-one

SMILES: O=C1NC=CC=C1O

InChI: InChI=1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)

InChIKey: GGOZGYRTNQBSSA-UHFFFAOYSA-N

PubChem CID: 28115

CAS: 119764-03-3

LOTUS: LTS0251924

NPASS: NPC318935

COCONUT: CNP0082051

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Chlamydomonas reinhardtii	Chlamydomonas	Chlamydomonadaceae	Chlamydomonadales	Chlorophyceae	Chlorophyta	Viridiplantae	Eukaryota

Molecule Weight: 111.09999999999998

TPSA？: 53.09

MolLogP？: 0.0805

Number of H-Donors: 2

Number of H-Acceptors: 2

RingCount: 1

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Agaricus bisporus	Tyrosinase	Inhibition	-9.0	%	10.1021/jm101266s
Bacillus anthracis	Anthrax lethal factor	Inhibition	-19.0	%	10.1021/jm101266s
Homo sapiens	Arachidonate 5-lipoxygenase	Inhibition	90.0	%	10.1021/jm101266s
Homo sapiens	D-amino-acid oxidase	IC50	1150.0	nM	10.1021/jm400095b
Homo sapiens	D-amino-acid oxidase	IC50	nan	None	10.1021/jm400095b
Homo sapiens	Histone deacetylase 1	IC50	20.0	nM	10.1021/jm301769u
Homo sapiens	Histone deacetylase 6	Inhibition	20.0	%	10.1021/jm301769u
Homo sapiens	Histone deacetylase 8	Inhibition	20.0	%	10.1021/jm301769u
Homo sapiens	Matrix metalloproteinase-1	Inhibition	8.0	%	10.1021/jm101266s
Homo sapiens	Matrix metalloproteinase-2	Inhibition	-18.0	%	10.1021/jm101266s
Homo sapiens	Matrix metalloproteinase 3	Inhibition	-7.0	%	10.1021/jm101266s
Homo sapiens	Matrix metalloproteinase 8	Inhibition	7.0	%	10.1021/jm101266s
Homo sapiens	Matrix metalloproteinase 9	Inhibition	21.0	%	10.1021/jm101266s
Homo sapiens	THP-1	IC50	10.0	ug.mL-1	10.1016/j.bmcl.2014.08.060
Leishmania donovani	Leishmania donovani	IC50	10.0	ug.mL-1	10.1016/j.bmcl.2014.08.060
Leishmania donovani	Leishmania donovani	IC50	40.0	ug.mL-1	10.1016/j.bmcl.2014.08.060
Mus musculus	Nitric oxide synthase, inducible	Inhibition	0.0	%	10.1021/jm101266s
Mus musculus	P388	ID50	300.0	uM	10.1021/jm00368a010
Vibrio harveyi	Vibrio harveyi	Activity	nan	None	10.1016/j.bmcl.2008.01.081
None	ADMET	Peff	nan	None	10.1021/jm400095b