N-Allylnorgalanthamine
AlkaPlorer ID: AK066560
Synonym: ''
IUPAC Name: (1S,12S,14R)-9-methoxy-4-prop-2-enyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol
Structure
SMILES: C=CCN1CC[C@@]23C=C[C@H](O)C[C@@H]2OC2=C(OC)C=CC(=C23)C1
InChI: InChI=1S/C19H23NO3/c1-3-9-20-10-8-19-7-6-14(21)11-16(19)23-18-15(22-2)5-4-13(12-20)17(18)19/h3-7,14,16,21H,1,8-12H2,2H3/t14-,16-,19-/m0/s1
InChIKey: BQESVZIPHFRYNG-QOKNQOGYSA-N
Reference
N-Alkylated galanthamine derivatives: Potent acetylcholinesterase inhibitors from Leucojum aestivum
PubChem CID: 44447598
LOTUS: LTS0164841
SuperNatural Ⅲ: SN0032441-01
NPASS: NPC40389
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Leucojum aestivum | Leucojum | Amaryllidaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 313.39700000000005
TPSA？: 41.93000000000001
MolLogP？: 2.4065000000000003
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Electrophorus electricus | Acetylcholinesterase | IC50 | 180.0 | nM | 10.1016/j.bmcl.2008.03.008 |