1,4-Butanediamine; N,N'-Bis(phenylacetyl)
AlkaPlorer ID: AK069102
Synonym: N,N'-1,4-Butanediylbis[benzeneacetamide], N,N'-Bis(phenylacetyl)putrescine, Aglaiduline, Aglanthine
IUPAC Name: 2-phenyl-N-[4-[(2-phenylacetyl)amino]butyl]acetamide
Structure
SMILES: O=C(CC1=CC=CC=C1)NCCCCNC(=O)CC1=CC=CC=C1
InChI: InChI=1S/C20H24N2O2/c23-19(15-17-9-3-1-4-10-17)21-13-7-8-14-22-20(24)16-18-11-5-2-6-12-18/h1-6,9-12H,7-8,13-16H2,(H,21,23)(H,22,24)
InChIKey: GYLIXRZGMBZSMD-UHFFFAOYSA-N
Reference
Infraspecific Variation of Sulfur-Containing Bisamides from <i>Aglaia</i> <i>leptantha</i>
PubChem CID: 2162324
LOTUS: LTS0224818
SuperNatural Ⅲ: SN0118692
NPASS: NPC172128
COCONUT: CNP0176205
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Aglaia leptantha | Aglaia | Meliaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Aglaia edulis | Aglaia | Meliaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 324.4239999999999
TPSA？: 58.2
MolLogP？: 2.4844
Number of H-Donors: 2
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Leishmania donovani | Leishmania donovani | IC50 | 280000.0 | nM | 10.1016/j.bmcl.2012.11.072 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 15000.0 | nM | 10.1016/j.bmcl.2012.11.072 |
| Rattus norvegicus | L6 | IC50 | 280000.0 | nM | 10.1016/j.bmcl.2012.11.072 |
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | IC50 | 110000.0 | nM | 10.1016/j.bmcl.2012.11.072 |
| Trypanosoma cruzi | Trypanosoma cruzi | IC50 | 280000.0 | nM | 10.1016/j.bmcl.2012.11.072 |