Oxyprotostemonine
AlkaPlorer ID: AK069552
Synonym: None
IUPAC Name: (5Z)-4-methoxy-3-methyl-5-[(1R,4S,5R,6S,8S,9S)-4-methyl-9-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-2,14-dioxa-10-azatetracyclo[6.5.1.01,5.06,10]tetradecan-3-ylidene]furan-2-one
Structure
SMILES: COC1=C(C)C(=O)O/C1=C1\O[C@]23CCCN4[C@H]([C@@H]5C[C@H](C)C(=O)O5)[C@H](C[C@H]4[C@H]2[C@@H]1C)O3
InChI: InChI=1S/C23H29NO7/c1-10-8-14(28-21(10)25)17-15-9-13-16-11(2)19(20-18(27-4)12(3)22(26)29-20)31-23(16,30-15)6-5-7-24(13)17/h10-11,13-17H,5-9H2,1-4H3/b20-19-/t10-,11-,13-,14-,15-,16+,17+,23+/m0/s1
InChIKey: YPHURJCNLMUQQJ-UHKURQFNSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Stemona curtisii | Stemona | Stemonaceae | Pandanales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Stemona kerrii | Stemona | Stemonaceae | Pandanales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 431.4850000000002
TPSA？: 83.53000000000002
MolLogP？: 2.2410999999999994
Number of H-Donors: 0
Number of H-Acceptors: 8
RingCount: 6
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Anopheles minimus | Anopheles minimus | LC50 | 4.0 | ppm | 10.1021/np034066u |
| Homo sapiens | Acetylcholinesterase | MIC | 2.32 | nM | 10.1021/np100474y |
| Homo sapiens | Acetylcholinesterase | MIC | 1000.0 | ng | 10.1021/np100474y |