Tetradecylamine
AlkaPlorer ID: AK069791
Synonym: None
IUPAC Name: tetradecan-1-amine
Structure
SMILES: CCCCCCCCCCCCCCN
InChI: InChI=1S/C14H31N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h2-15H2,1H3
InChIKey: PLZVEHJLHYMBBY-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Crinum asiaticum | Crinum | Amaryllidaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 213.409
TPSA？: 26.02
MolLogP？: 4.646200000000003
Number of H-Donors: 1
Number of H-Acceptors: 1
RingCount: 0
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Hepacivirus hominis | Hepatitis C virus | Activity | nan | None | 10.1016/j.bmcl.2013.12.121 |
| Homo sapiens | 786-0 | GI50 | 100000.0 | nM | None |
| Homo sapiens | A498 | GI50 | 100000.0 | nM | None |
| Homo sapiens | ACHN | GI50 | 100000.0 | nM | None |
| Homo sapiens | BT-474 | Activity | nan | None | 10.1021/acs.jmedchem.7b01198 |
| Homo sapiens | BT-474 | Activity | nan | None | 10.1039/C6MD00328A |
| Homo sapiens | BT-474 | CC50 | 27100.0 | nM | 10.1016/j.ejmech.2014.03.057 |
| Homo sapiens | BT-474 | CC50 | nan | None | 10.1021/acs.jmedchem.7b01198 |
| Homo sapiens | BT-549 | CC50 | 21700.0 | nM | 10.1016/j.ejmech.2014.03.057 |
| Homo sapiens | BT-549 | GI50 | 100000.0 | nM | None |
| Homo sapiens | CAKI-1 | GI50 | 100000.0 | nM | None |
| Homo sapiens | CCRF-CEM | GI50 | 100000.0 | nM | None |
| Homo sapiens | COLO 205 | GI50 | 100000.0 | nM | None |
| Homo sapiens | DU-145 | Activity | nan | None | 10.1039/C6MD00328A |
| Homo sapiens | DU-145 | CC50 | 16500.0 | nM | 10.1021/acs.jmedchem.7b01198 |
| Homo sapiens | DU-145 | CC50 | 16800.0 | nM | 10.1016/j.ejmech.2014.03.057 |
| Homo sapiens | DU-145 | GI50 | 100000.0 | nM | None |
| Homo sapiens | Dynamin-1 | IC50 | 20250.0 | nM | 10.1016/j.bmcl.2004.03.096 |
| Homo sapiens | EKVX | GI50 | 100000.0 | nM | None |
| Homo sapiens | HCC 2998 | GI50 | 100000.0 | nM | None |
| Homo sapiens | HCT-116 | GI50 | 100000.0 | nM | None |
| Homo sapiens | HCT-15 | GI50 | 100000.0 | nM | None |
| Homo sapiens | HL-60 | GI50 | 100000.0 | nM | None |
| Homo sapiens | HOP-62 | GI50 | 100000.0 | nM | None |
| Homo sapiens | HOP-92 | GI50 | 100000.0 | nM | None |
| Homo sapiens | Hs-578T | GI50 | 100000.0 | nM | None |
| Homo sapiens | HT-29 | GI50 | 100000.0 | nM | None |
| Homo sapiens | IGROV-1 | GI50 | 100000.0 | nM | None |
| Homo sapiens | JIMT-1 | CC50 | 27000.0 | nM | 10.1021/acs.jmedchem.7b01198 |
| Homo sapiens | K562 | GI50 | 100000.0 | nM | None |
| Homo sapiens | KM12 | GI50 | 100000.0 | nM | None |
| Homo sapiens | LOX IMVI | GI50 | 100000.0 | nM | None |
| Homo sapiens | Malme-3M | GI50 | 100000.0 | nM | None |
| Homo sapiens | MCF7 | GI50 | 100000.0 | nM | None |
| Homo sapiens | MDA-MB-231 | CC50 | nan | None | 10.1021/acs.jmedchem.7b01198 |
| Homo sapiens | MDA-MB-231 | GI50 | 100000.0 | nM | None |
| Homo sapiens | MDA-MB-435 | GI50 | 100000.0 | nM | None |
| Homo sapiens | MDA-N | GI50 | 100000.0 | nM | None |
| Homo sapiens | MIA PaCa-2 | CC50 | 18000.0 | nM | 10.1021/acs.jmedchem.7b01198 |
| Homo sapiens | MOLT-4 | GI50 | 100000.0 | nM | None |
| Homo sapiens | NCI/ADR-RES | GI50 | 100000.0 | nM | None |
| Homo sapiens | NCI-H23 | GI50 | 100000.0 | nM | None |
| Homo sapiens | NCI-H322M | GI50 | 100000.0 | nM | None |
| Homo sapiens | NCI-H460 | GI50 | 100000.0 | nM | None |
| Homo sapiens | NCI-H522 | GI50 | 100000.0 | nM | None |
| Homo sapiens | OVCAR-3 | GI50 | 100000.0 | nM | None |
| Homo sapiens | OVCAR-4 | GI50 | 100000.0 | nM | None |
| Homo sapiens | OVCAR-5 | GI50 | 100000.0 | nM | None |
| Homo sapiens | OVCAR-8 | GI50 | 100000.0 | nM | None |
| Homo sapiens | PC-3 | CC50 | 24000.0 | nM | 10.1021/acs.jmedchem.7b01198 |
| Homo sapiens | PC-3 | CC50 | 24600.0 | nM | 10.1016/j.ejmech.2014.03.057 |
| Homo sapiens | PC-3 | GI50 | 100000.0 | nM | None |
| Homo sapiens | RPMI-8226 | GI50 | 100000.0 | nM | None |
| Homo sapiens | RXF 393 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SF-268 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SF-295 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SK-MEL-2 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SK-MEL-28 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SK-MEL-5 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SK-OV-3 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SN12C | GI50 | 100000.0 | nM | None |
| Homo sapiens | SNB-75 | GI50 | 100000.0 | nM | None |
| Homo sapiens | SW-620 | GI50 | 100000.0 | nM | None |
| Homo sapiens | T47D | GI50 | 100000.0 | nM | None |
| Homo sapiens | Thyroid hormone receptor beta-1 | Potency | 31622.8 | nM | None |
| Homo sapiens | TK-10 | GI50 | 100000.0 | nM | None |
| Homo sapiens | U-251 | GI50 | 100000.0 | nM | None |
| Homo sapiens | UACC-257 | GI50 | 100000.0 | nM | None |
| Homo sapiens | UACC-62 | GI50 | 100000.0 | nM | None |
| Human immunodeficiency virus | Human immunodeficiency virus | Activity | nan | None | 10.1016/j.bmcl.2013.12.121 |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC | 140000.0 | nM | 10.1016/j.bmc.2015.12.036 |
| Rattus norvegicus | N-acylethanolamine-hydrolyzing acid amidase | Inhibition | nan | % | 10.1016/j.bmc.2012.03.065 |
| None | NON-PROTEIN TARGET | CC50 | 18200.0 | nM | 10.1016/j.ejmech.2014.03.057 |
| None | NON-PROTEIN TARGET | CC50 | 24800.0 | nM | 10.1016/j.ejmech.2014.03.057 |