Huperzine E
AlkaPlorer ID: AK070158
Synonym: ''
IUPAC Name: (1R,2R,13R,15R)-11-hydroxy-15-methyl-6-azatetracyclo[8.6.0.01,6.02,13]hexadeca-8,10-dien-12-one
Structure
SMILES: C[C@@H]1C[C@H]2C(=O)C(O)=C3C=CCN4CCC[C@H]2[C@]34C1
InChI: InChI=1S/C16H21NO2/c1-10-8-11-12-4-2-6-17-7-3-5-13(15(19)14(11)18)16(12,17)9-10/h3,5,10-12,19H,2,4,6-9H2,1H3/t10-,11-,12-,16-/m1/s1
InChIKey: IRBNEBXOQHDOSE-DSZLRUIBSA-N
Reference
Lycopodium Alkaloids from <i>Huperzia serrata</i>
PubChem CID: 127052893
LOTUS: LTS0058913
SuperNatural Ⅲ: SN0153050-02
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Huperzia serrata | Huperzia | Lycopodiaceae | Lycopodiales | Lycopodiopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 259.349
TPSA？: 40.54
MolLogP？: 2.4479000000000006
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Acetyl-CoA acetyltransferase, mitochondrial | Inhibition | None | % | 10.1016/j.bmcl.2016.04.019 |