Oryzamide C
AlkaPlorer ID: AK072043
Synonym: None
IUPAC Name: (3S,6S,9R,12S,19S)-6-methyl-9-(2-methylpropyl)-3-(2-methylsulfanylethyl)-19-[(2S)-octan-2-yl]-12-propan-2-yl-1-oxa-4,7,10,13,16-pentazacyclononadecane-2,5,8,11,14,17-hexone
Structure
SMILES: CCCCCC[C@H](C)[C@@H]1CC(O)=NCC(O)=N[C@@H](C(C)C)C(O)=N[C@H](CC(C)C)C(O)=N[C@@H](C)C(O)=N[C@@H](CCSC)C(=O)O1
InChI: InChI=1S/C32H57N5O7S/c1-9-10-11-12-13-21(6)25-17-26(38)33-18-27(39)37-28(20(4)5)31(42)36-24(16-19(2)3)30(41)34-22(7)29(40)35-23(14-15-45-8)32(43)44-25/h19-25,28H,9-18H2,1-8H3,(H,33,38)(H,34,41)(H,35,40)(H,36,42)(H,37,39)/t21-,22-,23-,24+,25-,28-/m0/s1
InChIKey: LRQDGGBYOKMXOJ-BJGQMJBWSA-N
Reference
Oryzamides A–E, Cyclodepsipeptides from the Sponge-Derived Fungus <i>Nigrospora oryzae</i> PF18
PubChem CID: 134154968
LOTUS: LTS0251994
NPASS: NPC487157
{NPAtlas: NPA021993
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Nigrospora oryzae | Nigrospora | Apiosporaceae | Xylariales | Sordariomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 655.9030000000001
TPSA？: 189.25
MolLogP？: 6.640400000000007
Number of H-Donors: 5
Number of H-Acceptors: 8
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Escherichia coli | Escherichia coli | Activity | nan | None | 10.1021/acs.jnatprod.6b00349 |
| Staphylococcus aureus | Staphylococcus aureus | Activity | nan | None | 10.1021/acs.jnatprod.6b00349 |
| None | NON-PROTEIN TARGET | Activity | nan | None | 10.1021/acs.jnatprod.6b00349 |
| None | NON-PROTEIN TARGET | IC50 | 31300.0 | nM | 10.1021/acs.jnatprod.6b00349 |
| None | Unchecked | Inhibition | nan | % | 10.1021/acs.jnatprod.6b00349 |