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nevirapine

AlkaPlorer ID: AK076620

Synonym: None

IUPAC Name: 2-cyclopropyl-7-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one

Structure

SMILES: CC1=CC=NC2=C1N=C(O)C1=CC=CN=C1N2C1CC1

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InChI: InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)

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InChIKey: NQDJXKOVJZTUJA-UHFFFAOYSA-N

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Properties Information

Molecule Weight: 266.30400000000003

TPSA？: 61.61000000000001

MolLogP？: 3.0352200000000007

Number of H-Donors: 1

Number of H-Acceptors: 4

RingCount: 4

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter baumannii Acinetobacter baumannii Inhibition 29.17 % 10.6019/CHEMBL4513141
Aspergillus fumigatus Aspergillus fumigatus IZ nan None 10.1007/s00044-012-0143-6
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Candida albicans Candida albicans Inhibition 2.39 % 10.6019/CHEMBL4513141
Candida albicans Candida albicans IZ nan None 10.1007/s00044-012-0143-6
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Chlorocebus sabaeus Vero CC50 27100.0 nM 10.1021/jm901653e
Chlorocebus sabaeus Vero CC50 100000.0 nM 10.1016/j.bmcl.2016.06.065
Chlorocebus sabaeus Vero CC50 nan None 10.1007/s00044-007-9004-0
Chlorocebus sabaeus Vero IC50 100.0 ug.mL-1 10.1016/j.ejmech.2016.04.019
Cryptococcus neoformans Cryptococcus neoformans Inhibition -2.57 % 10.6019/CHEMBL4513141
Escherichia coli Escherichia coli Inhibition -0.52 % 10.6019/CHEMBL4513141
Escherichia coli Escherichia coli IZ nan None 10.1007/s00044-012-0143-6
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01583-08
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1128/aac.01583-08
Homo sapiens A-375 Activity 35.0 % 10.1021/jm200734j
Homo sapiens A-375 Activity 50.0 % 10.1021/jm200734j
Homo sapiens A-375 Activity nan None 10.1021/jm200734j
Homo sapiens A-375 Inhibition 35.0 % 10.1021/jm0507330
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 31190.3 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 15190.1 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 1020.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Aldehyde dehydrogenase 1A1 Potency 35481.3 nM None
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens ATP-binding cassette sub-family G member 2 Activity nan None 10.1128/aac.01527-10
Homo sapiens ATP-binding cassette sub-family G member 2 Inhibition nan % 10.1128/aac.01527-10
Homo sapiens Beta-1 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile salt export pump IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Bile salt export pump IC50 135000.0 nM 10.1093/toxsci/kfq269
Homo sapiens Bile salt export pump IC50 294600.0 nM 10.1124/dmd.112.047068
Homo sapiens Bradykinin B1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens C8166 CC50 321000.0 nM 10.1016/0960-894X(95)00257-T
Homo sapiens C8166 EC50 100000.0 nM 10.1021/jm960802y
Homo sapiens C8166 EC90 0.12 uM 10.1021/jm031147e
Homo sapiens C8166 EC90 0.12 uM 10.1021/jm040854k
Homo sapiens C8166 EC90 30.0 uM 10.1021/jm040854k
Homo sapiens C8166 IC100 0.1 uM 10.1016/S0960-894X(00)80468-0
Homo sapiens C8166 IC50 40.0 nM 10.1016/0960-894X(95)00257-T
Homo sapiens C8166 IC50 40.0 nM 10.1021/jm00024a010
Homo sapiens C8166 Selectivity index 8025.0 None 10.1016/0960-894X(95)00257-T
Homo sapiens Caco-2 logPapp -4.52 None 10.1016/j.bmc.2009.08.022
Homo sapiens Caco-2 logPapp -4.52 None 10.1016/j.bmc.2011.03.011
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity 121.0 % 10.1021/jm7015683
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity nan None 10.1124/dmd.106.012765
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity nan None 10.1128/aac.01527-10
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 2 Activity nan None 10.1124/dmd.106.012765
Homo sapiens Canalicular multispecific organic anion transporter 2 Activity nan None 10.1128/aac.01527-10
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens CCRF-CEM CC50 4000.0 nM 10.1016/j.ejmech.2007.12.015
Homo sapiens CCRF-CEM CC50 25000.0 nM 10.1039/C3MD00036B
Homo sapiens CCRF-CEM CC50 50000.0 nM 10.1016/j.ejmech.2007.01.003
Homo sapiens CCRF-CEM CC50 50000.0 nM 10.1016/j.ejmech.2008.02.039
Homo sapiens CCRF-CEM CC50 100000.0 nM 10.1016/j.bmcl.2016.06.065
Homo sapiens CCRF-CEM CC50 10000000.0 nM 10.1021/jm101614j
Homo sapiens CCRF-CEM EC50 110.0 nM 10.1021/jm00050a015
Homo sapiens CCRF-CEM EC50 80000.0 nM 10.1021/jm00050a015
Homo sapiens CCRF-CEM IC50 5.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 8.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 29.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 61.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 70.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 84.0 nM 10.1021/jm950669u
Homo sapiens CCRF-CEM IC50 180.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 207.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 222.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 1440.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 1880.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 8270.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM IC50 8300.0 nM 10.1021/jm010212m
Homo sapiens CCRF-CEM TC50 nan None 10.1021/jm060103d
Homo sapiens CEM-SS CC50 nan None 10.1016/j.bmc.2016.05.010
Homo sapiens CEM-SS CC50 nan None 10.1016/j.bmcl.2007.11.114
Homo sapiens CEM-SS CC50 nan None 10.1016/j.bmcl.2007.12.015
Homo sapiens CEM-SS TC50 1.0 uM 10.1016/j.bmcl.2010.09.034
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Corticotropin releasing factor receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Corticotropin releasing factor receptor 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 Activity 32.0 % 10.1021/acs.jmedchem.0c02245
Homo sapiens Cytochrome P450 Drug metabolism nan None 10.1021/acs.jmedchem.9b01990
Homo sapiens Cytochrome P450 Kcat/Km 83.7 /M/min 10.1021/acs.jmedchem.9b01990
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 1A2 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2B6 Activity nan None None
Homo sapiens Cytochrome P450 2B6 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Inhibition 12.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2C19 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C8 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2C9 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2C9 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2D6 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A4 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 3A4 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Cytochrome P450 3A4 Ratio IC50 2.0 None 10.1021/tx300075j
Homo sapiens Delta opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 44668.4 nM None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 50118.7 nM None
Homo sapiens DNA polymerase beta Potency 35481.3 nM None
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine D5 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Endothelin receptor ET-B AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Gastric inhibitory polypeptide receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Geminin Potency 18356.4 nM None
Homo sapiens Geminin Potency 29092.9 nM None
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucagon receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens H9 Cell toxicity 10.0 uM 10.1016/S0960-894X(00)80468-0
Homo sapiens H9 EC50 100000.0 nM 10.1021/jm960802y
Homo sapiens H9 IC50 5000.0 nM 10.1016/s0960-894x(00)00398-x
Homo sapiens H9 IC90 78.0 nM 10.1016/S0960-894X(00)80468-0
Homo sapiens HEK293 CC50 10000.0 nM 10.1016/j.bmcl.2006.01.066
Homo sapiens HEK293 CC50 10000.0 nM 10.1016/j.bmcl.2006.01.073
Homo sapiens HEK293 CC50 10000.0 nM 10.1016/j.bmcl.2006.04.012
Homo sapiens HEK293 CC50 10000.0 nM 10.1016/j.bmcl.2006.05.073
Homo sapiens HEK293 IC50 nan None 10.1021/np5006955
Homo sapiens HEK-293T Activity 93.26 % 10.1016/j.ejmech.2020.112071
Homo sapiens HEK-293T Activity nan None 10.1016/j.ejmech.2014.07.072
Homo sapiens HEK-293T CC50 23720.0 nM 10.1016/j.ejmech.2020.112071
Homo sapiens HEK-293T CC50 92700.0 nM 10.1021/acsmedchemlett.8b00549
Homo sapiens HeLa Activity nan None 10.1073/pnas.0704212104
Homo sapiens HeLa CC50 4000.0 nM 10.1016/j.bmcl.2015.01.058
Homo sapiens HeLa IC50 56.0 nM 10.1021/jm0004906
Homo sapiens HeLa IC50 72.0 nM 10.1021/jm0004906
Homo sapiens HeLa IC50 89.0 nM 10.1021/jm0004906
Homo sapiens HeLa IC50 340.0 nM 10.1021/jm0004906
Homo sapiens HeLa IC50 340.0 nM 10.1021/jm040072r
Homo sapiens HeLa IC50 2200.0 nM 10.1021/jm0004906
Homo sapiens HeLa IC50 2200.0 nM 10.1021/jm040072r
Homo sapiens HeLa IC50 7100.0 nM 10.1021/jm0004906
Homo sapiens HeLa IC50 7100.0 nM 10.1021/jm040072r
Homo sapiens HeLa IC50 10000.0 nM 10.1021/jm0004906
Homo sapiens HeLa IC50 10000.0 nM 10.1021/jm040072r
Homo sapiens HeLa IC50 21000.0 nM 10.1021/jm0004906
Homo sapiens HeLa IC50 21000.0 nM 10.1021/jm040072r
Homo sapiens HeLa IC50 50000.0 nM 10.1021/jm0004906
Homo sapiens HeLa IC50 50000.0 nM 10.1021/jm040072r
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Ki nan None None
Homo sapiens Histamine H1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histamine H3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone deacetylase 6 Inhibition -75.42 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition 7.27 % 10.6019/CHEMBL4808148
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens CL 0.3 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL 0.3 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL_renal 0.0069 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL_renal 0.01 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 8.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens F 90.0 % 10.1124/dmd.111.041665
Homo sapiens Homo sapiens F 93.0 % 10.1016/j.bmc.2007.08.060
Homo sapiens Homo sapiens Fa 1.0 None 10.1021/jm901371v
Homo sapiens Homo sapiens F_fraction 0.93 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fg 0.94 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fh 0.99 None 10.1021/jm901371v
Homo sapiens Homo sapiens Metabolism 2.0 pM min-1 10.1021/jm9707030
Homo sapiens Homo sapiens Vdss 1.3 L.kg-1 10.1021/jm901371v
Homo sapiens HuT78 CC50 14000.0 nM 10.1021/acs.jmedchem.5b01183
Homo sapiens Importin subunit beta-1/Snurportin-1 Potency 5623.4 nM None
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Jurkat CC50 nan None 10.1021/jm0613121
Homo sapiens Kappa opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens Liver microsome CL 1.2e-05 mL.min-1.g-1 10.1124/dmd.111.039180
Homo sapiens Liver microsome Drug metabolism 1.2 pmol/min 10.1124/dmd.111.039180
Homo sapiens Liver microsome PB 19.1 pmol 10.1124/dmd.111.039180
Homo sapiens Liver microsomes Activity 19.0 pmol 10.1021/tx300075j
Homo sapiens Liver microsomes Stability nan % 10.1021/tx300075j
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase ERK2 Potency 3548.1 nM None
Homo sapiens MAP kinase ERK2 Potency 8912.5 nM None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens Monoamine oxidase A AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MT2 CC50 10000.0 nM 10.1016/j.bmcl.2005.10.037
Homo sapiens MT2 CC50 10000.0 nM 10.1016/j.bmcl.2005.10.038
Homo sapiens MT2 CC50 10000.0 nM 10.1016/j.bmcl.2006.08.037
Homo sapiens MT2 CC50 10000.0 nM 10.1021/jm00062a027
Homo sapiens MT2 CC50 10000.0 nM 10.1021/jm070683u
Homo sapiens MT2 CC50 96171.0 nM 10.1016/j.ejmech.2019.111987
Homo sapiens MT2 CC50 100000.0 nM 10.1016/j.bmc.2016.07.039
Homo sapiens MT2 CC50 100000.0 nM 10.1016/j.bmcl.2010.03.006
Homo sapiens MT2 CC50 100000.0 nM 10.1016/j.bmcl.2011.12.132
Homo sapiens MT2 CC50 100000.0 nM 10.1016/j.bmcl.2012.11.115
Homo sapiens MT2 CC50 100000.0 nM 10.1016/j.bmcl.2013.06.091
Homo sapiens MT2 CC50 100000.0 nM 10.1016/j.bmcl.2013.06.093
Homo sapiens MT2 CC50 100000.0 nM 10.1016/j.bmcl.2019.06.047
Homo sapiens MT2 CC50 100000.0 nM 10.1021/acsmedchemlett.0c00612
Homo sapiens MT2 CC50 100000.0 nM 10.1021/jm201134m
Homo sapiens MT2 CC50 100000.0 nM 10.1021/ml5003713
Homo sapiens MT2 CC50 320000.0 nM 10.1016/j.bmcl.2014.08.019
Homo sapiens MT2 EC50 100000.0 nM 10.1021/acs.jmedchem.1c01758
Homo sapiens MT2 IC50 303.0 nM 10.1021/jm00069a011
Homo sapiens MT4 Activity 32.0 uM 10.1128/aac.00986-09
Homo sapiens MT4 CC50 4.0 ug.mL-1 10.1007/s00044-011-9662-9
Homo sapiens MT4 CC50 4.0 ug.mL-1 10.1007/s00044-011-9664-7
Homo sapiens MT4 CC50 4.0 ug.mL-1 10.1007/s00044-011-9705-2
Homo sapiens MT4 CC50 4.0 ug.mL-1 10.1007/s00044-011-9776-0
Homo sapiens MT4 CC50 4.0 ug.mL-1 10.1007/s00044-012-0129-4
Homo sapiens MT4 CC50 4.0 ug.mL-1 10.1007/s00044-013-0567-7
Homo sapiens MT4 CC50 4.0 ug.mL-1 10.1016/j.bmc.2008.11.056
Homo sapiens MT4 CC50 4.0 ug.mL-1 10.1016/j.ejmech.2016.04.019
Homo sapiens MT4 CC50 5.0 ug.mL-1 10.1016/j.ejmech.2012.04.038
Homo sapiens MT4 CC50 15.0 nM 10.1021/acs.jmedchem.7b00332
Homo sapiens MT4 CC50 20.0 ug.mL-1 10.1021/jm00093a002
Homo sapiens MT4 CC50 4000.0 nM 10.1016/j.bmc.2012.12.027
Homo sapiens MT4 CC50 4000.0 nM 10.1016/j.bmcl.2018.10.010
Homo sapiens MT4 CC50 4000.0 nM 10.1016/j.ejmech.2018.01.016
Homo sapiens MT4 CC50 4600.0 nM 10.1016/j.ejmech.2019.111864
Homo sapiens MT4 CC50 7000.0 nM 10.1021/acs.jmedchem.8b01238
Homo sapiens MT4 CC50 7000.0 nM 10.1021/jm070811e
Homo sapiens MT4 CC50 7000.0 nM 10.1021/jm500284x
Homo sapiens MT4 CC50 7000.0 nM 10.1021/jm800340w
Homo sapiens MT4 CC50 7500.0 nM 10.1016/j.bmcl.2006.03.080
Homo sapiens MT4 CC50 7500.0 nM 10.1021/jm050744t
Homo sapiens MT4 CC50 7500.0 nM 10.1021/jm201308v
Homo sapiens MT4 CC50 7500.0 nM 10.1021/jm801330n
Homo sapiens MT4 CC50 7510.0 nM 10.1021/jm101626c
Homo sapiens MT4 CC50 9500.0 nM 10.1016/j.ejmech.2020.113063
Homo sapiens MT4 CC50 9510.0 nM 10.1016/j.ejmech.2020.112237
Homo sapiens MT4 CC50 14400.0 nM 10.1016/j.bmc.2014.08.001
Homo sapiens MT4 CC50 14900.0 nM 10.1016/j.bmc.2012.12.049
Homo sapiens MT4 CC50 14990.0 nM 10.1016/j.bmc.2014.02.029
Homo sapiens MT4 CC50 14990.0 nM 10.1016/j.ejmech.2012.10.036
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2008.06.012
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2009.06.068
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2009.12.059
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2010.05.081
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2011.08.025
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2012.07.026
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2012.09.058
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2013.09.009
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2013.09.051
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2014.01.054
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2014.02.030
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2014.03.020
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2014.07.018
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2015.01.002
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2015.03.037
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2016.05.010
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmc.2017.03.009
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmcl.2007.01.025
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmcl.2007.11.114
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmcl.2007.12.015
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmcl.2012.09.062
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmcl.2013.10.059
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmcl.2017.03.009
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.bmcl.2018.03.012
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2011.08.011
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2012.02.019
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2012.04.004
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2014.07.104
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2015.01.042
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2015.02.022
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2016.10.009
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2019.111874
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2020.112811
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2021.113769
Homo sapiens MT4 CC50 15000.0 nM 10.1016/j.ejmech.2022.114563
Homo sapiens MT4 CC50 15000.0 nM 10.1021/acs.jmedchem.1c00128
Homo sapiens MT4 CC50 15000.0 nM 10.1021/acs.jmedchem.1c00708
Homo sapiens MT4 CC50 15000.0 nM 10.1021/acs.jmedchem.1c01015
Homo sapiens MT4 CC50 15000.0 nM 10.1021/acs.jmedchem.1c01676
Homo sapiens MT4 CC50 15000.0 nM 10.1021/acs.jmedchem.2c00468
Homo sapiens MT4 CC50 15000.0 nM 10.1021/acs.jmedchem.5b01183
Homo sapiens MT4 CC50 15000.0 nM 10.1021/acs.jmedchem.8b01729
Homo sapiens MT4 CC50 15000.0 nM 10.1021/acs.jnatprod.5b00116
Homo sapiens MT4 CC50 15000.0 nM 10.1021/jm070382k
Homo sapiens MT4 CC50 15000.0 nM 10.1021/np500271u
Homo sapiens MT4 CC50 15020.0 nM 10.1007/s00044-009-9220-x
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2009.07.028
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2010.03.007
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2010.05.036
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2011.05.024
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2011.07.023
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2011.10.002
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2012.04.030
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2013.08.040
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2013.12.045
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2014.11.032
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2015.09.020
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2016.07.041
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2017.05.040
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2017.12.033
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2018.03.003
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2020.115431
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmc.2021.116195
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.bmcl.2008.09.055
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2009.06.037
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2013.04.052
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2014.02.047
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2014.09.054
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2016.02.068
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2017.02.047
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2017.07.012
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2018.03.059
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2020.112549
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2020.113051
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2021.113204
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2022.114471
Homo sapiens MT4 CC50 15020.0 nM 10.1016/j.ejmech.2022.114512
Homo sapiens MT4 CC50 15020.0 nM 10.1021/acsmedchemlett.8b00054
Homo sapiens MT4 CC50 15020.0 nM 10.1039/C3MD00028A
Homo sapiens MT4 CC50 15020.0 nM 10.1039/C3MD00247K
Homo sapiens MT4 CC50 15021.0 nM 10.1016/j.ejmech.2014.05.059
Homo sapiens MT4 CC50 15021.0 nM 10.1016/j.ejmech.2015.08.007
Homo sapiens MT4 CC50 15030.0 nM 10.1016/j.bmc.2021.116239
Homo sapiens MT4 CC50 15030.0 nM 10.1016/j.ejmech.2019.111603
Homo sapiens MT4 CC50 15030.0 nM 10.1016/j.ejmech.2019.111619
Homo sapiens MT4 CC50 15030.0 nM 10.1021/acs.jmedchem.9b01446
Homo sapiens MT4 CC50 18000.0 nM 10.1016/j.bmc.2016.04.010
Homo sapiens MT4 CC50 18776.0 nM 10.1016/j.ejmech.2014.04.027
Homo sapiens MT4 CC50 18776.0 nM 10.1016/j.ejmech.2020.112696
Homo sapiens MT4 CC50 18776.0 nM 10.1021/acs.jmedchem.6b01906
Homo sapiens MT4 CC50 18776.0 nM 10.1021/jm300477h
Homo sapiens MT4 CC50 18776.0 nM 10.1021/jm5011622
Homo sapiens MT4 CC50 31631.0 nM 10.1016/j.ejmech.2006.11.014
Homo sapiens MT4 CC50 50000.0 nM 10.1016/j.ejmech.2007.12.015
Homo sapiens MT4 CC50 80000.0 nM 10.1021/jm00050a015
Homo sapiens MT4 CC50 80000.0 nM 10.1021/jm00094a009
Homo sapiens MT4 CC50 100000.0 nM 10.1016/j.ejmech.2009.08.012
Homo sapiens MT4 CC50 100000.0 nM 10.1021/jm031147e
Homo sapiens MT4 CC50 100000.0 nM 10.1021/jm500139a
Homo sapiens MT4 CC50 156000.0 nM 10.1016/j.ejmech.2010.10.020
Homo sapiens MT4 CC50 200000.0 nM 10.1016/j.bmcl.2004.04.008
Homo sapiens MT4 CC50 200000.0 nM 10.1016/j.ejmech.2007.08.001
Homo sapiens MT4 CC50 200000.0 nM 10.1016/j.ejmech.2008.09.013
Homo sapiens MT4 CC50 200000.0 nM 10.1016/S0960-894X(97)00340-5
Homo sapiens MT4 CC50 200000.0 nM 10.1021/jm010853h
Homo sapiens MT4 CC50 200000.0 nM 10.1021/jm061167r
Homo sapiens MT4 CC50 200000.0 nM 10.1021/jm980260f
Homo sapiens MT4 CC50 200000.0 nM 10.1021/jm9901125
Homo sapiens MT4 CC50 290000.0 nM 10.1021/jm00012a002
Homo sapiens MT4 CC50 300000.0 nM 10.1021/jm950568w
Homo sapiens MT4 CC50 300000.0 nM 10.1021/jm960802y
Homo sapiens MT4 CC50 325130.0 nM 10.1021/jm201506e
Homo sapiens MT4 CC50 325130.0 nM 10.1021/jm400102x
Homo sapiens MT4 CC50 376000.0 nM 10.1021/jm00017a010
Homo sapiens MT4 CC50 683000.0 nM 10.1016/j.bmc.2007.10.013
Homo sapiens MT4 CC50 683000.0 nM 10.1016/j.bmc.2010.06.067
Homo sapiens MT4 CC50 683000.0 nM 10.1021/jm9802012
Homo sapiens MT4 CD50 100.0 uM 10.1021/jm020949r
Homo sapiens MT4 ClC95 100.0 nM 10.1021/jm00041a023
Homo sapiens MT4 EC50 30.0 nM 10.1021/jm9802012
Homo sapiens MT4 EC50 32.0 nM 10.1021/jm040127p
Homo sapiens MT4 EC50 73.0 nM 10.1021/jm00012a002
Homo sapiens MT4 EC50 120.0 nM 10.1021/jm00050a015
Homo sapiens MT4 EC50 128.0 nM 10.1021/jm00094a009
Homo sapiens MT4 EC50 250.0 nM 10.1021/jm960802y
Homo sapiens MT4 EC50 250.0 nM 10.1021/jm980260f
Homo sapiens MT4 EC50 300.0 nM 10.1016/s0960-894x(99)00664-2
Homo sapiens MT4 EC50 300.0 nM 10.1021/jm00017a010
Homo sapiens MT4 EC50 300.0 nM 10.1021/jm950568w
Homo sapiens MT4 EC50 310.0 nM 10.1021/jm960802y
Homo sapiens MT4 EC50 320.0 nM 10.1021/jm040127p
Homo sapiens MT4 EC50 350.0 nM 10.1021/jm9901125
Homo sapiens MT4 EC50 370.0 nM 10.1021/jm010853h
Homo sapiens MT4 EC50 370.0 nM 10.1021/jm0309856
Homo sapiens MT4 EC50 370.0 nM 10.1021/jm040854k
Homo sapiens MT4 EC50 6310.0 nM 10.1021/jm040127p
Homo sapiens MT4 EC50 10000.0 nM 10.1021/jm040127p
Homo sapiens MT4 EC50 30000.0 nM 10.1021/jm010853h
Homo sapiens MT4 EC50 30000.0 nM 10.1021/jm0309856
Homo sapiens MT4 EC50 30000.0 nM 10.1021/jm040854k
Homo sapiens MT4 EC50 80000.0 nM 10.1021/jm00050a015
Homo sapiens MT4 EC50 100000.0 nM 10.1021/jm040127p
Homo sapiens MT4 EC50 100000.0 nM 10.1021/jm960802y
Homo sapiens MT4 EC50 nan nM 10.1021/jm040127p
Homo sapiens MT4 ED50 0.15 uM 10.1021/jm950639r
Homo sapiens MT4 ED50 0.62 uM 10.1021/jm950639r
Homo sapiens MT4 ED50 5.0 uM 10.1021/jm990095j
Homo sapiens MT4 ED50 8.0 uM 10.1021/jm950639r
Homo sapiens MT4 ED50 10.0 uM 10.1021/jm950639r
Homo sapiens MT4 ED50 22.0 uM 10.1021/jm950639r
Homo sapiens MT4 IC50 0.22 ug.mL-1 10.1021/jm00010a010
Homo sapiens MT4 IC50 10.0 ug.mL-1 10.1021/jm00010a010
Homo sapiens MT4 IC50 32.0 nM 10.1016/j.bmcl.2003.09.045
Homo sapiens MT4 IC50 32.0 nM 10.1016/s0960-894x(01)00410-3
Homo sapiens MT4 IC50 96.0 nM 10.1021/jm030255y
Homo sapiens MT4 IC50 316.0 nM 10.1016/s0960-894x(01)00410-3
Homo sapiens MT4 IC50 600.0 nM 10.1016/s0960-894x(04)00205-7
Homo sapiens MT4 IC50 5010.0 nM 10.1016/s0960-894x(01)00410-3
Homo sapiens MT4 IC50 6300.0 nM 10.1016/j.bmcl.2003.09.045
Homo sapiens MT4 IC50 6310.0 nM 10.1016/s0960-894x(01)00410-3
Homo sapiens MT4 IC50 7940.0 nM 10.1016/s0960-894x(01)00410-3
Homo sapiens MT4 IC50 10000.0 nM 10.1016/j.bmcl.2003.09.045
Homo sapiens MT4 IC50 10000.0 nM 10.1016/s0960-894x(01)00410-3
Homo sapiens MT4 IC50 17200.0 nM 10.1021/jm030255y
Homo sapiens MT4 IC50 100000.0 nM 10.1016/s0960-894x(01)00410-3
Homo sapiens MT4 IC50 640000.0 nM 10.1021/jm9901125
Homo sapiens MT4 IC50 nan nM 10.1016/j.bmcl.2004.04.008
Homo sapiens MT4 IC50 nan nM 10.1016/s0960-894x(01)00412-7
Homo sapiens MT4 IC95 100.0 nM 10.1021/jm00054a009
Homo sapiens MT4 IC95 100.0 nM 10.1021/jm00099a007
Homo sapiens MT4 IC95 100.0 nM 10.1021/jm00113a036
Homo sapiens MT4 IC95 400.0 nM 10.1021/jm00061a022
Homo sapiens MT4 Ratio 625.0 None 10.1021/jm00050a015
Homo sapiens MT4 Ratio 1000.0 None 10.1021/jm950568w
Homo sapiens MT4 Selectivity index 526.0 None 10.1021/jm00093a002
Homo sapiens MT4 Selectivity index 666.0 None 10.1021/jm010853h
Homo sapiens MT4 Selectivity index 800.0 SI 10.1021/jm980260f
Homo sapiens MT4 SI 1250.0 None 10.1021/jm00017a010
Homo sapiens Multidrug resistance-associated protein 1 Activity nan None 10.1124/dmd.106.012765
Homo sapiens Multidrug resistance-associated protein 1 Activity nan None 10.1128/aac.01527-10
Homo sapiens Multidrug resistance-associated protein 4 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Mu opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Neurotensin receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens PBMC CC50 40.88 ug.mL-1 10.1016/j.bmc.2011.01.024
Homo sapiens PBMC CC50 100000.0 nM 10.1016/j.bmcl.2016.06.065
Homo sapiens PBMC CC50 1003000.0 nM 10.1016/j.ejmech.2019.111714
Homo sapiens PBMC IC50 40.0 nM 10.1016/j.bmc.2017.03.061
Homo sapiens PBMC IC90 180.0 nM 10.1016/j.bmc.2017.03.061
Homo sapiens PBMC TC50 10.0 uM 10.1016/j.bmc.2017.03.061
Homo sapiens Peroxisome proliferator-activated receptor gamma Potency 50118.7 nM None
Homo sapiens P-glycoprotein 1 Activity nan None 10.1128/aac.01527-10
Homo sapiens P-glycoprotein 1 Inhibition nan % 10.1128/aac.01527-10
Homo sapiens Phosphodiesterase 3A AC50 4500.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4B Inhibition nan % 10.1016/j.bmcl.2007.12.015
Homo sapiens Phosphodiesterase 4D AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Phosphodiesterase 6A AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Plasma T1/2 30.0 hr 10.1128/aac.00692-07
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Prelamin-A/C Potency 35.5 nM None
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 5a (5-HT5a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin 7 (5-HT7) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens Solute carrier organic anion transporter family member 1B1 Activity nan None 10.1128/aac.01527-10
Homo sapiens Thromboxane A2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 6513.1 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 8199.5 nM None
Homo sapiens TZM CC50 15000.0 nM 10.1016/j.ejmech.2020.113063
Homo sapiens TZM CC50 nan None 10.1021/acs.jmedchem.1c01104
Homo sapiens U2OS Activity nan None 10.1016/j.bmc.2016.02.038
Homo sapiens U2OS Activity nan None 10.1016/j.bmc.2016.04.018
Homo sapiens U2OS CC50 100000.0 nM 10.1016/j.bmc.2016.04.018
Homo sapiens Ubiquitin carboxyl-terminal hydrolase 1 Potency 631.0 nM None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Human immunodeficiency virus Human immunodeficiency virus Activity 98.0 % 10.1007/s00044-012-0143-6
Human immunodeficiency virus Human immunodeficiency virus EC50 0.005 ug.mL-1 10.1021/jm100093p
Human immunodeficiency virus Human immunodeficiency virus EC50 0.012 ug.mL-1 10.1021/jm100093p
Human immunodeficiency virus Human immunodeficiency virus EC50 0.016 ug.mL-1 10.1021/jm100093p
Human immunodeficiency virus Human immunodeficiency virus EC50 0.023 ug.mL-1 10.1016/j.bmc.2008.11.056
Human immunodeficiency virus Human immunodeficiency virus EC50 0.2 ug.mL-1 10.1021/jm100093p
Human immunodeficiency virus Human immunodeficiency virus EC50 4.0 ug.mL-1 10.1016/j.bmc.2008.11.056
Human immunodeficiency virus Human immunodeficiency virus EC50 50.0 nM 10.1016/j.bmcl.2006.09.047
Human immunodeficiency virus Human immunodeficiency virus EC50 74.0 nM 10.1016/j.bmcl.2012.12.049
Human immunodeficiency virus Human immunodeficiency virus EC50 10000.0 nM 10.1016/j.bmcl.2012.12.049
Human immunodeficiency virus Human immunodeficiency virus EC50 20000.0 nM 10.1021/jm0512490
Human immunodeficiency virus Human immunodeficiency virus IC50 100.0 nM 10.1007/s00044-012-0143-6
Human immunodeficiency virus Human immunodeficiency virus Inhibition nan % 10.1128/aac.01583-08
Human immunodeficiency virus Human immunodeficiency virus Ratio EC50 100.0 None 10.1016/j.bmcl.2012.12.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity 0.01 % 10.1016/j.bmc.2016.02.038
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity 0.36 % 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity 0.5 % 10.1016/j.bmc.2016.04.018
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity 23.0 % 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity nan None 10.1016/j.bmc.2008.09.051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity nan None 10.1016/j.bmc.2017.03.061
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity nan None 10.1021/acs.jmedchem.1c01676
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity nan None 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 CC50 749100.0 nM 10.1016/j.bmcl.2010.12.003
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.007 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.008 ug.mL-1 10.1021/jm100093p
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.01 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.02 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.038 ug.mL-1 10.1021/jm00093a002
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.05 ug.mL-1 10.1007/s00044-011-9662-9
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.05 ug.mL-1 10.1007/s00044-011-9664-7
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.05 ug.mL-1 10.1007/s00044-011-9705-2
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.05 ug.mL-1 10.1007/s00044-011-9776-0
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.05 ug.mL-1 10.1016/j.bmc.2011.09.018
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.05 ug.mL-1 10.1039/d2md00076h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.7 nM 10.1016/j.ejmech.2020.112071
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.703 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.852 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 0.997 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1.5 nM 10.1016/j.bmcl.2007.11.114
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1.5 nM 10.1016/j.bmcl.2007.12.015
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2.02 ug.mL-1 10.1016/j.bmc.2015.09.020
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3.2 nM 10.1016/j.ejmech.2019.111864
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4.88 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6.7 nM 10.1016/j.ejmech.2019.111864
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8.2 nM 10.1021/jm901653e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8.94 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9.32 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10.0 nM 10.1016/j.ejmech.2007.12.015
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10.0 nM 10.1021/acs.jnatprod.5b00116
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10.0 nM 10.1021/jm040838n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 14.0 nM 10.1016/j.ejmech.2019.111864
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 14.4 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 14.88 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15.0 nM 10.1021/jm070382k
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 19.2 nM 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 19.2 nM 10.1021/jm101614j
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 19.2 nM 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 20.0 nM 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 23.0 nM 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 24.0 nM 10.1016/j.ejmech.2018.01.016
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 24.0 nM 10.1039/C3MD00036B
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 24.17 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 24.63 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 25.99 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 27.0 nM 10.1016/j.bmcl.2015.01.058
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 27.0 nM 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 30.0 nM 10.1016/j.bmc.2007.10.013
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 30.0 nM 10.1016/j.bmc.2014.04.018
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 30.0 nM 10.1016/j.bmcl.2007.01.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 31.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 31.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 33.3 nM 10.1016/j.ejmech.2006.11.014
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 34.0 nM 10.1016/j.ejmech.2019.111864
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 34.09 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 34.14 nM 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 35.0 nM 10.1021/jm060103d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 39.0 nM 10.1021/jm801438e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 39.8 nM 10.1021/jm040838n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 40.0 nM 10.1016/j.bmcl.2016.06.065
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 41.0 nM 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 42.6 nM 10.1021/jm901653e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 48.0 nM 10.1016/j.bmc.2012.12.027
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 50.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 50.0 nM 10.1016/j.bmcl.2006.01.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 50.0 nM 10.1016/j.bmcl.2006.04.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 50.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 50.0 nM 10.1016/j.bmcl.2006.05.096
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 50.0 nM 10.1016/j.ejmech.2007.12.015
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 50.0 nM 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 52.0 nM 10.1021/jm050744t
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 53.0 nM 10.1016/j.bmcl.2007.11.114
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 53.0 nM 10.1016/j.bmcl.2007.12.015
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 53.0 nM 10.1021/jm070382k
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 53.0 nM 10.1021/jm1002952
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 58.0 nM 10.1016/j.ejmech.2018.01.016
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 60.0 nM 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 60.0 nM 10.1021/jm500139a
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 60.0 nM 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 68.0 nM 10.1021/jm201506e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 68.0 nM 10.1021/jm400102x
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 72.8 nM 10.1016/j.ejmech.2020.113063
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 73.0 nM 10.1016/j.bmc.2008.06.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 73.0 nM 10.1016/j.bmc.2009.06.068
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 73.0 nM 10.1016/j.bmc.2009.12.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 73.0 nM 10.1016/j.bmcl.2007.01.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 73.0 nM 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 75.0 nM 10.1016/j.bmc.2010.05.036
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 75.0 nM 10.1016/j.bmc.2011.08.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 79.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 79.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 80.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 80.0 nM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 81.0 nM 10.1021/jm040840e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 81.0 nM 10.1021/jm201134m
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 84.0 nM 10.1016/j.bmc.2013.08.040
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 84.0 nM 10.1016/j.bmcl.2017.03.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 84.0 nM 10.1016/j.ejmech.2020.113063
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 85.0 nM 10.1021/jm030558s
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 87.9 nM 10.1021/acs.jmedchem.0c00117
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 90.0 nM 10.1016/j.bmc.2012.09.058
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 90.0 nM 10.1016/j.bmc.2014.03.020
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 90.0 nM 10.1016/j.bmcl.2012.09.062
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 90.0 nM 10.1021/jm0512490
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 90.0 nM 10.1039/C3MD00028A
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 90.1 nM 10.1016/j.ejmech.2012.02.019
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 97.0 nM 10.1016/j.ejmech.2012.10.036
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 97.5 nM 10.1021/jm901653e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 100.0 nM 10.1016/j.bmcl.2018.10.010
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 100.0 nM 10.1021/acs.jnatprod.5b00025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 100.0 nM 10.1021/jm060103d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 101.0 nM 10.1016/j.bmc.2014.02.030
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 102.0 nM 10.1016/j.bmc.2010.05.081
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.bmc.2013.09.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.bmc.2016.05.010
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.bmc.2016.07.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.bmcl.2006.08.037
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.bmcl.2010.03.006
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.bmcl.2012.11.115
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.bmcl.2013.06.091
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.bmcl.2013.06.093
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.ejmech.2012.04.038
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1016/j.ejmech.2013.04.052
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1021/acsmedchemlett.0c00612
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1021/jm070683u
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1021/jm201134m
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1021/ml5003713
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1039/C3MD00247K
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110.0 nM 10.1128/aac.00911-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 112.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 112.4 nM 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 112.4 nM 10.1016/j.ejmech.2020.112696
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 112.4 nM 10.1021/acs.jmedchem.6b01906
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 112.4 nM 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 113.0 nM 10.1016/j.bmc.2013.09.051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 114.9 nM 10.1016/j.bmc.2021.116195
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 116.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 116.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 120.0 nM 10.1016/j.bmcl.2005.10.037
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 120.0 nM 10.1016/j.bmcl.2005.10.038
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 120.0 nM 10.1016/j.ejmech.2007.01.003
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 120.0 nM 10.1016/j.ejmech.2008.02.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 120.0 nM 10.1016/j.ejmech.2016.10.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 120.0 nM 10.1016/j.ejmech.2021.113769
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 120.0 nM 10.1021/acs.jmedchem.8b01238
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 120.0 nM 10.1021/jm500284x
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 125.42 nM 10.1016/j.bmc.2018.03.003
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 130.0 nM 10.1016/j.ejmech.2010.10.020
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 130.0 nM 10.1021/jm201308v
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 130.0 nM 10.1021/jm800340w
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 130.0 nM 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 131.4 nM 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 132.7 nM 10.1016/j.bmc.2021.116195
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 144.0 nM 10.1016/j.bmc.2014.08.005
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 148.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 148.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 150.0 nM 10.1016/j.bmcl.2011.12.090
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 150.0 nM 10.1016/j.bmcl.2012.01.133
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 150.0 nM 10.1016/j.bmcl.2012.10.134
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 150.0 nM 10.1016/j.bmcl.2014.10.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 150.0 nM 10.1016/j.ejmech.2014.07.104
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 150.0 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 150.0 nM 10.1016/j.ejmech.2021.113204
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 150.0 nM 10.1021/ml300146q
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 150.0 nM 10.1128/aac.00911-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 151.36 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 158.0 nM 10.1016/j.ejmech.2022.114471
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 159.0 nM 10.1016/j.ejmech.2022.114471
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 159.6 nM 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 160.0 nM 10.1016/j.bmc.2021.116239
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 160.0 nM 10.1016/j.ejmech.2016.10.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 160.0 nM 10.1021/acs.jmedchem.8b01729
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 162.0 nM 10.1016/j.bmc.2010.05.081
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 163.0 nM 10.1016/j.ejmech.2020.112237
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 163.0 nM 10.1128/aac.01795-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 164.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 164.0 nM 10.1016/j.bmcl.2006.04.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 164.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 164.0 nM 10.1016/j.bmcl.2006.05.096
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 164.0 nM 10.1016/j.ejmech.2020.112811
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 164.0 nM 10.1021/acs.jmedchem.2c00468
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 170.0 nM 10.1016/j.bmc.2014.02.029
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 170.0 nM 10.1016/j.bmcl.2013.10.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 170.0 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 170.0 nM 10.1016/j.ejmech.2022.114512
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 170.0 nM 10.1016/j.ejmech.2022.114563
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 170.0 nM 10.1021/acs.jmedchem.2c00468
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 170.0 nM 10.1128/aac.00911-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 180.0 nM 10.1016/j.bmc.2011.07.023
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 180.0 nM 10.1016/j.bmc.2014.01.054
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 180.0 nM 10.1016/j.bmc.2014.07.018
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 180.0 nM 10.1016/j.bmc.2014.08.001
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 180.0 nM 10.1016/j.bmc.2017.05.040
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 180.0 nM 10.1016/j.bmc.2017.12.033
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 180.0 nM 10.1016/j.bmc.2020.115431
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 180.0 nM 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 180.0 nM 10.1016/j.ejmech.2019.111619
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 182.0 nM 10.1021/acs.jmedchem.1c01015
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 190.0 nM 10.1016/j.bmc.2013.12.045
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 190.0 nM 10.1016/j.bmc.2014.11.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 190.0 nM 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 190.0 nM 10.1021/jm400102x
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 191.0 nM 10.1016/j.ejmech.2020.112811
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 197.5 nM 10.1016/j.ejmech.2022.114512
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 199.0 nM 10.1016/j.bmc.2012.12.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 199.0 nM 10.1016/j.bmcl.2007.01.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 200.0 nM 10.1016/j.bmc.2010.03.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 200.0 nM 10.1016/j.bmc.2012.07.026
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 200.0 nM 10.1016/j.bmcl.2010.09.034
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 200.0 nM 10.1016/j.ejmech.2015.07.043
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 200.0 nM 10.1016/j.ejmech.2019.111603
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 200.0 nM 10.1021/jm060103d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 200.4 nM 10.1016/j.bmc.2012.04.030
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 207.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 207.0 nM 10.1016/j.bmcl.2007.01.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 208.0 nM 10.1007/s00044-009-9220-x
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 208.0 nM 10.1016/j.bmc.2009.07.028
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 208.0 nM 10.1016/j.bmcl.2008.09.055
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 208.0 nM 10.1016/j.ejmech.2009.06.037
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 209.0 nM 10.1016/j.ejmech.2006.11.014
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 209.0 nM 10.1021/acs.jmedchem.1c00128
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 209.0 nM 10.1021/acs.jmedchem.1c00708
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 209.0 nM 10.1021/acs.jmedchem.1c01676
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 210.0 nM 10.1016/j.bmc.2011.05.024
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 210.0 nM 10.1016/j.bmc.2011.10.002
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 210.0 nM 10.1016/j.bmcl.2017.03.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 210.0 nM 10.1016/j.ejmech.2012.04.004
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 220.0 nM 10.1016/j.bmc.2016.05.010
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 230.0 nM 10.1016/j.bmc.2016.07.041
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 230.0 nM 10.1016/j.ejmech.2014.02.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 230.0 nM 10.1016/j.ejmech.2015.11.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 230.0 nM 10.1016/j.ejmech.2017.02.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 230.0 nM 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 235.0 nM 10.1016/j.ejmech.2019.111874
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 239.88 nM 10.1021/acs.jmedchem.8b01729
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 240.0 nM 10.1021/acs.jmedchem.8b01729
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 244.0 nM 10.1016/j.bmc.2015.03.037
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 250.0 nM 10.1016/j.bmcl.2014.08.019
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 250.0 nM 10.1016/j.ejmech.2008.09.013
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 250.0 nM 10.1016/j.ejmech.2017.07.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 250.0 nM 10.1016/j.ejmech.2018.08.002
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 250.0 nM 10.1016/S0960-894X(97)00340-5
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 250.0 nM 10.1021/acs.jmedchem.7b00332
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 252.0 nM 10.1021/jm801438e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 258.0 nM 10.1016/j.bmc.2021.116239
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 258.36 nM 10.1016/j.bmc.2016.07.041
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 260.0 nM 10.1016/j.ejmech.2015.11.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 260.0 nM 10.1016/j.ejmech.2017.02.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 260.0 nM 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 260.0 nM 10.1021/acs.jmedchem.5b01183
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 277.2 nM 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 280.0 nM 10.1016/j.bmc.2018.03.003
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 280.0 nM 10.1016/j.ejmech.2016.02.068
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 280.0 nM 10.1021/acs.jmedchem.5b01183
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 281.0 nM 10.1016/j.ejmech.2020.113063
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 288.0 nM 10.1021/acs.jmedchem.1c01676
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 288.4 nM 10.1021/acs.jmedchem.1c00708
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 289.0 nM 10.1016/j.ejmech.2015.08.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 290.0 nM 10.1021/jm8003009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 293.0 nM 10.1016/j.ejmech.2019.111603
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 293.0 nM 10.1021/acs.jmedchem.9b01446
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 294.0 nM 10.1021/acs.jmedchem.1c01015
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 300.0 nM 10.1016/j.bmcl.2019.06.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 300.0 nM 10.1016/j.ejmech.2009.08.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 300.0 nM 10.1021/jm010853h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 300.0 nM 10.1021/jm500139a
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 310.0 nM 10.1016/j.bmc.2014.11.032
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 310.0 nM 10.1016/j.bmc.2015.01.002
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 310.0 nM 10.1016/j.bmc.2016.04.010
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 310.0 nM 10.1016/j.ejmech.2014.09.054
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 310.0 nM 10.1016/j.ejmech.2015.02.022
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 310.0 nM 10.1128/aac.00911-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 311.7 nM 10.1016/j.bmc.2015.09.020
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 312.0 nM 10.1016/j.ejmech.2015.01.042
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 312.0 nM 10.1016/j.ejmech.2015.08.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 316.0 nM 10.1021/jm040838n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 330.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 350.0 nM 10.1128/aac.00911-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 370.0 nM 10.1021/jm0512490
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 370.0 nM 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 373.0 nM 10.1016/j.ejmech.2020.113063
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 380.0 nM 10.1016/j.ejmech.2019.111619
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 380.0 nM 10.1128/aac.00911-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 385.0 nM 10.1021/jm901653e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 400.0 nM 10.1016/j.ejmech.2018.01.016
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 400.0 nM 10.1021/jm031147e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 440.0 nM 10.1016/j.bmcl.2018.03.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 460.0 nM 10.1128/aac.00911-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 588.8 nM 10.1016/j.bmc.2021.116195
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 597.0 nM 10.1021/jm040840e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 600.0 nM 10.1021/jm901167t
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 620.0 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 638.0 nM 10.1021/jm030558s
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 700.0 nM 10.1016/j.ejmech.2021.113769
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 705.0 nM 10.1016/j.ejmech.2022.114471
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 710.0 nM 10.1016/j.ejmech.2016.10.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 720.0 nM 10.1021/jm060103d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 733.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 760.0 nM 10.1016/j.ejmech.2020.112071
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 792.0 nM 10.1021/jm801438e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 800.0 nM 10.1021/jm901167t
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 827.0 nM 10.1016/j.ejmech.2006.11.014
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 830.0 nM 10.1016/j.bmc.2016.07.041
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 830.0 nM 10.1016/j.ejmech.2015.11.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 830.0 nM 10.1016/j.ejmech.2017.02.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 830.0 nM 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 870.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 901.0 nM 10.1016/j.bmc.2014.02.030
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1000.0 nM 10.1016/j.bmcl.2010.09.034
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1000.0 nM 10.1021/jm040840e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1000.0 nM 10.1021/jm500139a
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1030.0 nM 10.1016/j.ejmech.2020.112811
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1090.0 nM 10.1021/jm060103d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1100.0 nM 10.1021/jm060103d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1240.0 nM 10.1016/j.ejmech.2019.111619
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1300.0 nM 10.1016/j.bmcl.2007.01.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1316.0 nM 10.1016/j.bmc.2010.05.081
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1360.0 nM 10.1021/acs.jmedchem.2c00468
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1400.0 nM 10.1016/j.ejmech.2020.112071
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1470.0 nM 10.1016/j.ejmech.2020.113063
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1502.0 nM 10.1021/jm300477h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1640.0 nM 10.1021/acs.jmedchem.8b01729
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1800.0 nM 10.1016/j.bmcl.2017.03.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1800.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1850.0 nM 10.1016/j.ejmech.2018.01.016
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1900.0 nM 10.1016/j.ejmech.2021.113769
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1920.0 nM 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1970.0 nM 10.1016/j.bmc.2013.08.040
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1980.0 nM 10.1016/j.ejmech.2006.11.014
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1990.0 nM 10.1016/j.ejmech.2019.111603
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2000.0 nM 10.1021/acs.jmedchem.1c01676
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2030.0 nM 10.1016/j.bmc.2010.05.081
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2200.0 nM 10.1016/j.ejmech.2016.10.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2216.0 nM 10.1021/acs.jmedchem.1c01015
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2221.0 nM 10.1016/j.ejmech.2022.114471
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2300.0 nM 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2322.1 nM 10.1016/j.bmc.2021.116195
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2325.0 nM 10.1016/j.ejmech.2020.113063
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2360.0 nM 10.1021/jm060103d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2410.0 nM 10.1021/jm030558s
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2467.0 nM 10.1021/jm030558s
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2500.0 nM 10.1016/j.bmcl.2007.01.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2500.0 nM 10.1016/j.bmcl.2013.10.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2524.0 nM 10.1016/j.bmc.2021.116239
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2560.1 nM 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2565.8 nM 10.1016/j.ejmech.2022.114512
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2580.0 nM 10.1016/j.ejmech.2020.112071
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2580.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2690.0 nM 10.1128/aac.01795-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2697.0 nM 10.1016/j.ejmech.2006.11.014
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2730.0 nM 10.1016/j.ejmech.2020.113063
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2850.0 nM 10.1016/j.ejmech.2021.113769
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2870.0 nM 10.1016/j.ejmech.2020.112071
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2879.0 nM 10.1021/jm040840e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2900.0 nM 10.1016/j.ejmech.2014.07.104
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2970.0 nM 10.1016/j.ejmech.2021.113769
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3000.0 nM 10.1021/jm500139a
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3001.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3250.0 nM 10.1016/j.bmc.2018.03.003
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3300.0 nM 10.1021/jm801438e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3300.0 nM 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3388.0 nM 10.1016/j.ejmech.2020.113063
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3430.0 nM 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3455.0 nM 10.1016/j.ejmech.2015.08.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3465.0 nM 10.1021/jm030558s
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3490.0 nM 10.1016/j.bmc.2011.10.002
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3500.0 nM 10.1016/j.bmc.2014.01.054
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3500.0 nM 10.1016/j.ejmech.2012.04.004
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3500.0 nM 10.1016/j.ejmech.2016.10.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3532.0 nM 10.1016/j.ejmech.2006.11.014
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3538.0 nM 10.1016/j.ejmech.2022.114471
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3551.0 nM 10.1016/j.ejmech.2022.114471
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3600.0 nM 10.1016/j.ejmech.2016.10.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3671.2 nM 10.1016/j.bmc.2021.116195
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3700.0 nM 10.1021/jm1002952
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3756.0 nM 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3756.0 nM 10.1016/j.ejmech.2020.112696
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3756.0 nM 10.1021/acs.jmedchem.6b01906
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3756.0 nM 10.1021/jm300477h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3756.0 nM 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3760.0 nM 10.1021/acs.jmedchem.0c00117
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3785.0 nM 10.1016/j.ejmech.2022.114471
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3800.0 nM 10.1016/j.ejmech.2016.10.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3900.0 nM 10.1021/jm050744t
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3900.0 nM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3920.0 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4000.0 nM 10.1016/j.bmcl.2018.10.010
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4000.0 nM 10.1016/j.ejmech.2018.01.016
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4000.0 nM 10.1021/jm500139a
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4090.0 nM 10.1016/j.ejmech.2014.02.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4090.0 nM 10.1016/j.ejmech.2021.113769
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4106.0 nM 10.1021/acs.jmedchem.1c00708
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4106.0 nM 10.1021/acs.jmedchem.1c01676
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4311.0 nM 10.1016/j.bmc.2021.116195
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4386.0 nM 10.1016/j.bmcl.2006.04.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4400.0 nM 10.1016/j.ejmech.2016.10.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4416.0 nM 10.1016/j.ejmech.2022.114471
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4530.0 nM 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4900.0 nM 10.1021/jm060103d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4960.0 nM 10.1021/jm800340w
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5000.0 nM 10.1016/j.bmc.2013.09.051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5050.0 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5053.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5053.0 nM 10.1016/j.bmcl.2006.04.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5053.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5053.0 nM 10.1016/j.bmcl.2006.05.096
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5100.0 nM 10.1016/j.ejmech.2020.112811
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5120.0 nM 10.1016/j.ejmech.2013.04.052
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5120.0 nM 10.1039/C3MD00247K
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5349.7 nM 10.1016/j.bmc.2021.116195
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5351.0 nM 10.1021/jm030558s
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5410.0 nM 10.1016/j.ejmech.2020.112811
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5600.0 nM 10.1021/acs.jmedchem.8b01238
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5600.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5600.0 nM 10.1021/jm500284x
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5780.0 nM 10.1016/j.ejmech.2021.113769
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5840.0 nM 10.1021/acs.jmedchem.2c00468
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5910.0 nM 10.1016/j.ejmech.2006.11.014
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6100.0 nM 10.1021/jm201308v
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6121.0 nM 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6151.0 nM 10.1021/jm901653e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6200.0 nM 10.1021/jm801438e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6210.0 nM 10.1016/j.bmc.2016.07.041
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6210.0 nM 10.1016/j.ejmech.2015.11.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6210.0 nM 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6220.0 nM 10.1016/j.ejmech.2017.02.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6310.0 nM 10.1021/jm040838n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6548.0 nM 10.1016/j.bmc.2021.116239
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6690.0 nM 10.1016/j.ejmech.2020.112811
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6729.0 nM 10.1016/j.bmc.2010.05.081
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6740.5 nM 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6748.0 nM 10.1016/j.ejmech.2020.113063
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6780.0 nM 10.1016/j.bmc.2016.07.041
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6780.0 nM 10.1016/j.ejmech.2015.11.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6780.0 nM 10.1016/j.ejmech.2017.02.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 6780.0 nM 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7000.0 nM 10.1016/j.ejmech.2009.08.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7000.0 nM 10.1021/acs.jmedchem.8b01238
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7000.0 nM 10.1021/jm500284x
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7000.0 nM 10.1021/jm800340w
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7078.0 nM 10.1016/j.ejmech.2006.11.014
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7150.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7170.0 nM 10.1016/j.bmc.2016.07.041
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7170.0 nM 10.1016/j.ejmech.2015.11.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7170.0 nM 10.1016/j.ejmech.2017.02.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7170.0 nM 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7180.0 nM 10.1016/j.ejmech.2019.111619
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7250.0 nM 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7500.0 nM 10.1021/jm050744t
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7500.0 nM 10.1021/jm201308v
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7500.0 nM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7500.0 nM 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7510.0 nM 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7580.0 nM 10.1016/j.ejmech.2014.09.054
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7585.0 nM 10.1016/j.ejmech.2015.08.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7590.0 nM 10.1016/j.bmc.2014.11.032
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7600.0 nM 10.1016/j.ejmech.2012.10.036
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7600.0 nM 10.1016/j.ejmech.2015.01.042
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7600.0 nM 10.1016/j.ejmech.2015.02.022
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7640.0 nM 10.1016/j.bmc.2016.05.010
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7700.0 nM 10.1016/j.ejmech.2020.112811
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 7711.6 nM 10.1016/j.ejmech.2022.114512
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8026.0 nM 10.1021/acs.jmedchem.1c00708
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8026.0 nM 10.1021/acs.jmedchem.1c01676
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8040.0 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8082.0 nM 10.1021/acs.jmedchem.1c00708
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8082.0 nM 10.1021/acs.jmedchem.1c01676
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8099.8 nM 10.1016/j.ejmech.2022.114512
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8458.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8458.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 8490.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9070.0 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9350.0 nM 10.1016/j.ejmech.2015.08.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9500.0 nM 10.1016/j.bmc.2011.07.023
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9510.0 nM 10.1021/acs.jmedchem.0c00117
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9513.0 nM 10.1016/j.ejmech.2020.112237
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9550.0 nM 10.1016/j.ejmech.2019.111603
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9610.0 nM 10.1016/j.bmc.2016.07.041
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9610.0 nM 10.1016/j.ejmech.2015.11.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9610.0 nM 10.1016/j.ejmech.2017.02.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9610.0 nM 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 9900.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1016/j.bmcl.2006.01.066
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1016/j.bmcl.2006.04.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1016/j.bmcl.2006.05.073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1016/j.bmcl.2006.05.096
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1021/jm040838n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1021/jm040840e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1021/jm201134m
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1021/jm201506e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1021/jm400102x
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1021/jm500139a
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1021/jm801438e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10260.0 nM 10.1016/j.bmc.2018.03.003
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10475.0 nM 10.1021/jm901653e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10490.0 nM 10.1016/j.bmc.2021.116239
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10654.0 nM 10.1016/j.bmc.2021.116195
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10900.0 nM 10.1021/acs.jmedchem.8b01729
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10960.0 nM 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 11000.0 nM 10.1016/j.bmc.2015.03.037
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 11000.0 nM 10.1016/j.bmcl.2012.09.062
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 11200.0 nM 10.1016/j.ejmech.2012.02.019
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 11200.0 nM 10.1016/j.ejmech.2019.111874
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 11510.0 nM 10.1021/acs.jmedchem.2c00468
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 12345.0 nM 10.1021/acs.jmedchem.1c01015
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 12429.0 nM 10.1016/j.ejmech.2015.08.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 13416.0 nM 10.1021/jm901653e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 14400.0 nM 10.1016/j.bmc.2014.08.001
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 14505.0 nM 10.1016/j.ejmech.2006.11.014
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 14570.0 nM 10.1016/j.ejmech.2020.112071
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 14800.0 nM 10.1021/jm8003009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1016/j.bmc.2010.05.081
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1016/j.bmc.2011.08.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1016/j.bmc.2012.07.026
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1016/j.bmc.2014.03.020
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1016/j.bmcl.2017.03.009
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1016/j.bmcl.2018.03.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1016/j.ejmech.2020.112811
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1021/acs.jmedchem.2c00468
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1021/acs.jmedchem.5b01183
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15000.0 nM 10.1021/acs.jmedchem.8b01729
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.bmc.2010.03.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.bmc.2010.05.036
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.bmc.2012.04.030
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.bmc.2018.03.003
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.ejmech.2016.02.068
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.ejmech.2017.07.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.ejmech.2021.113769
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15020.0 nM 10.1016/j.ejmech.2022.114512
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15021.0 nM 10.1016/j.ejmech.2015.08.007
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15021.0 nM 10.1021/acs.jmedchem.1c01015
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15030.0 nM 10.1016/j.ejmech.2019.111603
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15030.0 nM 10.1016/j.ejmech.2019.111619
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15031.0 nM 10.1016/j.bmc.2021.116239
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15037.0 nM 10.1016/j.bmc.2010.05.081
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 18850.0 nM 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 18916.0 nM 10.1021/jm300477h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 20000.0 nM 10.1016/j.ejmech.2009.08.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 20000.0 nM 10.1021/jm500139a
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 22000.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 23300.0 nM 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 30000.0 nM 10.1021/jm031147e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 51900.0 nM 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 75000.0 nM 10.1016/j.bmcl.2007.01.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 80000.0 nM 10.1016/j.ejmech.2020.112071
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 100000.0 nM 10.1016/j.ejmech.2020.112071
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 100000.0 nM 10.1021/jm030558s
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 100000.0 nM 10.1021/jm201134m
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 100000.0 nM 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 110000.0 nM 10.1021/acs.jmedchem.1c01758
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 210200.0 nM 10.1021/acs.jmedchem.9b01446
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 1502060.0 nM 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 2102300.0 nM 10.1021/acs.jmedchem.9b01446
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 5866700.0 nM 10.1021/acs.jmedchem.9b01446
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10075000.0 nM 10.1021/acs.jmedchem.9b01446
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 15866700.0 nM 10.1021/acs.jmedchem.9b01446
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 100000000.0 nM 10.1021/acs.jmedchem.1c01758
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan nM 10.1021/jm040838n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.bmc.2012.12.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.bmc.2016.05.010
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.bmc.2016.07.039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.bmc.2016.07.041
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.bmcl.2012.11.115
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.bmcl.2013.06.091
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.bmcl.2019.06.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.ejmech.2019.111864
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.ejmech.2021.113769
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1021/acs.jmedchem.1c00708
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1021/acs.jmedchem.1c01104
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1021/acs.jmedchem.5b01979
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1021/jm901167t
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1021/ml5003713
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1128/aac.00911-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC90 30.0 uM 10.1021/jm031147e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 0.64 uM 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 0.68 uM 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 0.69 uM 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 438.0 nM 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 464.0 nM 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC95 8000.0 nM 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 0.01 uM 10.1021/jm00062a027
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 0.04 uM 10.1016/j.bmcl.2008.09.070
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 0.12 uM 10.1016/s0960-894x(98)00249-2
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 0.15 uM 10.1016/s0960-894x(98)00249-2
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 0.38 uM 10.1021/jm020949r
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 0.57 uM 10.1021/jm020949r
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 0.62 uM 10.1016/s0960-894x(98)00249-2
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 0.68 uM 10.1016/j.bmcl.2008.09.070
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 2.0 uM 10.1016/j.bmcl.2008.09.070
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 4.3 uM 10.1021/jm020949r
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 22.0 uM 10.1016/s0960-894x(98)00249-2
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 22.0 uM 10.1021/jm020949r
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 50.0 nM 10.1021/jm070488f
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 90.0 nM 10.1021/jm070488f
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 100.0 uM 10.1021/jm020949r
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 14000.0 nM 10.1021/jm070488f
Human immunodeficiency virus 1 Human immunodeficiency virus 1 ED50 20000.0 nM 10.1021/jm070488f
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.13 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.2 None 10.1128/aac.01455-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.32 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.35 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.4 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.49 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.5 None 10.1128/aac.01593-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.67 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.7 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.7 None 10.1128/aac.01593-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.73 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.83 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.9 None 10.1128/aac.01455-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 0.94 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 1.0 None 10.1128/aac.01455-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 1.05 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 1.1 None 10.1128/aac.01593-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 1.25 None 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 1.3 None 10.1128/aac.01593-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 2.1 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 4.1 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 4.8 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 5.3 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 6.4 None 10.1128/aac.01455-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 8.4 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 9.2 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 12.2 None 10.1128/aac.01455-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 56.3 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 58.0 None 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 58.6 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 71.0 None 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 81.0 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 83.0 None 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 90.0 None 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 127.7 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 145.0 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 161.0 None 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 177.0 None 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 317.0 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 322.0 None 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 400.0 None 10.1128/aac.00870-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 519.0 None 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 FC 2152.0 None 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 0.1 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 0.4 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 0.5 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 1.0 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 1.1 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 1.3 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 1.9 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 2.1 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 2.3 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 2.4 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 2.8 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 4.2 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 5.9 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 12.0 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 32.0 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 39.0 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 42.0 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 46.0 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 51.0 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 100.0 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 122.0 None 10.1128/aac.01032-06
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Fold change 144.0 None 10.1021/jm0708230
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 0.01 ug.mL-1 10.1021/jm00010a010
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 0.05 ug.mL-1 10.1007/s00044-012-0129-4
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 0.05 ug.mL-1 10.1007/s00044-013-0567-7
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 0.075 ug.mL-1 10.1016/j.ejmech.2016.04.019
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 0.09 ug.mL-1 10.1016/j.bmc.2011.01.024
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 0.8 None 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 1.0 None 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 1.2 None 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 2.0 None 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 2.5 None 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10.0 nM 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10.0 nM 10.1021/np500271u
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 13.0 nM 10.1016/j.bmcl.2018.04.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 14.0 nM 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 20.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 22.0 nM 10.1016/j.bmcl.2018.04.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 24.0 nM 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 26.0 nM 10.1016/j.bmc.2016.04.018
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 30.0 nM 10.1016/j.bmc.2010.06.067
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 30.0 nM 10.1016/j.bmc.2017.03.061
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 30.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 31.0 nM 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 31.6 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 32.0 nM 10.1016/s0960-894x(01)00412-7
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 32.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 34.0 nM 10.1016/s0960-894x(01)00011-7
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 40.0 nM 10.1016/j.bmc.2017.03.061
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 40.0 nM 10.1016/j.bmcl.2011.02.074
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 40.0 nM 10.1016/S0960-894X(00)80447-3
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 40.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 40.0 nM 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 40.0 nM 10.1039/C3MD00337J
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 44.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 50.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 50.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 50.0 nM 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 50.0 nM 10.1021/np5006955
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 51.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 53.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 56.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 59.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 60.0 nM 10.1016/j.bmc.2008.11.075
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 60.0 nM 10.1021/jm801470b
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 65.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 71.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 83.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 87.0 nM 10.1021/ml3000462
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 89.0 nM 10.1021/jm040072r
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 89.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 90.0 nM 10.1016/j.bmc.2011.05.062
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 100.0 nM 10.1016/j.bmcl.2014.08.020
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 100.0 nM 10.1021/acs.jmedchem.6b00730
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 100.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 101.0 nM 10.1016/j.ejmech.2014.05.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 118.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 120.0 nM 10.1016/j.bmcl.2014.08.020
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 130.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 135.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 135.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 150.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 156.0 nM 10.1021/acs.jnatprod.7b00004
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 163.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 163.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 190.0 nM 10.1016/j.ejmech.2019.111714
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 190.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 195.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 195.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 200.0 nM 10.1021/jm049606e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 250.0 nM 10.1016/j.ejmech.2007.08.001
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 250.0 nM 10.1021/jm061167r
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 290.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 294.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 300.0 nM 10.1016/j.ejmech.2019.111714
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 304.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 310.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 316.0 nM 10.1016/s0960-894x(01)00412-7
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 316.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 316.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 409.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 420.0 nM 10.1016/j.bmc.2016.04.018
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 440.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 500.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 500.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 509.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 509.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 520.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 532.0 nM 10.1021/acs.jnatprod.7b00004
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 801.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 900.0 nM 10.1016/j.ejmech.2014.05.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 910.0 nM 10.1016/j.bmcl.2018.04.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 940.0 nM 10.1016/j.ejmech.2019.111714
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 1200.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 1290.0 nM 10.1039/C3MD00337J
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 1450.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 1452.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 1452.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 1868.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 2000.0 nM 10.1021/jm8004493
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 2300.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 2800.0 nM 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 2860.0 nM 10.1016/j.bmcl.2018.04.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 2900.0 nM 10.1021/jm801470b
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 4980.0 nM 10.1016/j.bmc.2017.03.061
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 5000.0 nM 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 5010.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 5012.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 5012.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 5480.0 nM 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 5800.0 nM 10.1021/jm050670l
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 6310.0 nM 10.1016/s0960-894x(01)00412-7
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 6310.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 6310.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 6310.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 6600.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 7940.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 7943.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 7943.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 8000.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 8200.0 nM 10.1021/jm050670l
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 9000.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 9400.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 9800.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1016/j.bmc.2017.03.061
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1016/j.bmcl.2006.05.096
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1016/s0960-894x(01)00412-7
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1021/jm801470b
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10000.0 nM 10.1039/C3MD00337J
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 10300.0 nM 10.1021/jm050670l
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 11000.0 nM 10.1021/jm801470b
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 15000.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 16100.0 nM 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 66700.0 nM 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 100000.0 nM 10.1016/s0960-894x(00)00398-x
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 100000.0 nM 10.1016/s0960-894x(01)00412-7
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 100000.0 nM 10.1021/acs.jnatprod.7b00004
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 100000.0 nM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 100000.0 nM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 100000.0 nM 10.1021/jm900802y
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 140000.0 nM 10.1016/j.ejmech.2019.111714
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 200000.0 nM 10.1021/acs.jmedchem.6b00730
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 232300.0 nM 10.1016/j.ejmech.2019.111714
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 30.0 nM 10.1016/j.bmc.2017.03.061
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 50.0 nM 10.1021/jm990580e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 350.0 nM 10.1016/j.bmc.2017.03.061
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 540.0 nM 10.1016/j.bmc.2017.03.061
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 5100.0 nM 10.1021/jm990580e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 10000.0 nM 10.1016/j.bmc.2017.03.061
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 10200.0 nM 10.1021/jm990580e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC90 nan None 10.1021/jm990580e
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition 50.0 % 10.1128/aac.00692-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition 76.0 % 10.1016/j.ejmech.2019.111866
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition 77.0 % 10.1016/j.ejmech.2019.111900
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition 100.0 % 10.1016/j.bmc.2011.01.024
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition nan % 10.1016/j.bmc.2015.06.048
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition nan % 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition nan % 10.1021/acsmedchemlett.7b00524
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Inhibition nan % 10.1128/aac.00692-07
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 0.4 None 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 0.6 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 0.8 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 0.9 None 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 1.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 1.2 None 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 1.4 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 1.74 None 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 1.8 None 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 1.8 None 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2.0 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2.3 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2.5 None 10.1021/jm300477h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2.5 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2.6 None 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2.8 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2.9 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 3.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 3.2 None 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 3.4 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 3.8 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 4.3 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 4.4 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 4.6 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 5.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 6.3 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 7.0 None 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 7.3 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 12.75 None 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 13.6 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 16.04 None 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 18.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 20.4 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 23.9 None 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 24.0 None 10.1016/j.ejmech.2015.01.042
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 26.1 None 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 27.6 None 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 33.0 None 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 33.0 None 10.1016/j.ejmech.2020.112696
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 33.0 None 10.1021/acs.jmedchem.6b01906
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 33.0 None 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 33.9 None 10.1016/j.bmcl.2018.03.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 37.0 None 10.1016/j.ejmech.2018.03.059
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 38.0 None 10.1021/jm800340w
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 41.6 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 41.8 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 42.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 42.23 None 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 42.5 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 43.0 None 10.1021/acs.jmedchem.0c00117
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 43.0 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 47.0 None 10.1021/acs.jmedchem.8b01238
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 47.0 None 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 47.0 None 10.1021/jm201308v
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 47.0 None 10.1021/jm500284x
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 48.25 None 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 49.0 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 51.6 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 58.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 59.4 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 63.7 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 65.7 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 68.64 None 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 69.0 None 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 71.5 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 75.0 None 10.1016/j.bmc.2012.04.030
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 77.3 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 83.0 None 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 86.6 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 91.0 None 10.1128/aac.01480-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 96.9 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 99.1 None 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 108.0 None 10.1021/acs.jmedchem.0c00117
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 139.9 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 140.0 None 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 141.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 157.7 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 166.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 200.0 None 10.1016/j.bmc.2011.08.025
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 205.2 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 317.4 None 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 358.3 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 429.9 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 468.1 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 1013.0 None 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 1370.0 None 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2155.9 None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2256.0 None 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 2439.0 None 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 3703.0 None 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 9411.4 None 10.1016/j.bmc.2021.116531
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 nan None 10.1021/acs.jmedchem.1c01104
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio EC50 nan None 10.1128/aac.00986-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.4 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.4 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.5 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.5 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.6 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.6 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.7 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.7 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.8 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.8 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.9 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 0.9 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.0 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.1 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.1 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.2 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.3 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.3 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.4 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.4 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.7 None 10.1016/j.bmcl.2018.04.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 1.7 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 2.0 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 2.1 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 2.2 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 2.4 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 2.4 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 2.5 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 2.9 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 3.1 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 3.4 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 3.8 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 4.4 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 5.0 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 7.0 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 8.3 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 22.0 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 32.0 None 10.1039/C3MD00337J
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 49.6 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 70.0 None 10.1016/j.bmcl.2018.04.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 70.9 None 10.1128/aac.01335-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 89.0 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 90.0 None 10.1016/j.ejmech.2016.07.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 96.0 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 161.0 None 10.1016/j.ejmech.2016.07.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 177.0 None 10.1016/j.ejmech.2016.07.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 220.0 None 10.1016/j.bmcl.2018.04.049
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 222.0 None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 250.0 None 10.1039/C3MD00337J
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 322.0 None 10.1016/j.ejmech.2016.07.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 519.0 None 10.1016/j.ejmech.2016.07.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 2152.0 None 10.1016/j.ejmech.2016.07.047
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Ratio IC50 nan None 10.1128/aac.01156-08
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Selectivity index 500.0 None 10.1021/jm040838n
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Selectivity index 5012.0 uM 10.1021/jm0407658
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Selectivity ratio 3.2 None 10.1016/j.bmcl.2006.04.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Selectivity ratio 16.5 None 10.1128/aac.01795-09
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Selectivity ratio 88.0 None 10.1016/j.bmcl.2006.04.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Selectivity ratio 101.0 None 10.1016/j.bmcl.2006.04.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Selectivity ratio 200.0 uM 10.1016/j.bmcl.2006.04.012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 SI 5012.0 uM 10.1021/jm0408621
Human immunodeficiency virus 1 Human immunodeficiency virus 1 SI 227667.0 None 10.1021/jm9802012
Human immunodeficiency virus 1 Human immunodeficiency virus 1 TIME 7.2 hr 10.1128/aac.01064-10
Human immunodeficiency virus 1 Human immunodeficiency virus 1 TIME 8.3 hr 10.1016/j.ejmech.2014.07.072
Human immunodeficiency virus 1 Human immunodeficiency virus 1 TIME 10.0 hr 10.1021/jm100093p
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 integrase IC50 nan None 10.1016/j.ejmech.2010.05.070
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 protease IC50 101.0 nM 10.1021/jm00061a022
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 protease IC50 11300.0 nM 10.1021/jm00061a022
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 protease IC50 57900.0 nM 10.1021/jm00061a022
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity 0.03 uM 10.1021/jm010580q
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity 1.0 % 10.1016/j.bmc.2011.05.062
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity 6.5 uM 10.1128/aac.00749-06
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity 9.0 % 10.1016/j.bmc.2016.04.018
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity 11.4 % 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity 13.7 % 10.1016/j.bmc.2016.04.018
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity 21.7 % 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity nan None 10.1021/jm0613121
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity nan None 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Activity nan None 10.1128/aac.00749-06
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase CD50 188.0 uM 10.1021/jm00025a010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 3.6 nM 10.1016/j.bmc.2010.01.023
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 20.0 nM 10.1016/s0960-894x(01)00510-8
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 26.0 nM 10.1016/s0960-894x(01)00510-8
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 30.0 nM 10.1016/s0960-894x(01)00510-8
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 52.0 nM 10.1016/j.bmcl.2006.03.080
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 53.0 nM 10.1016/s0960-894x(01)00510-8
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 70.0 nM 10.1016/s0960-894x(01)00510-8
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 75.0 nM 10.1016/j.bmc.2017.12.033
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 100.0 nM 10.1016/s0960-894x(01)00510-8
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 110.0 nM 10.1016/s0960-894x(01)00510-8
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 124.0 nM 10.1021/acsmedchemlett.8b00054
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 240.0 nM 10.1016/j.bmc.2017.03.009
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 250.0 nM 10.1021/jm050273a
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 271.0 nM 10.1021/acs.jmedchem.7b00332
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 380.0 nM 10.1016/s0960-894x(01)00510-8
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 450.0 nM 10.1016/j.bmc.2017.12.033
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 1700.0 nM 10.1021/np400683h
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 2100.0 nM 10.1021/acs.jmedchem.7b00332
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 3900.0 nM 10.1016/j.bmcl.2006.03.080
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 4106.0 nM 10.1021/acs.jmedchem.1c00128
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 5390.0 nM 10.1021/acs.jmedchem.7b00332
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 7500.0 nM 10.1016/j.bmcl.2006.03.080
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 8026.0 nM 10.1021/acs.jmedchem.1c00128
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 8082.0 nM 10.1021/acs.jmedchem.1c00128
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 9590.0 nM 10.1016/j.bmc.2017.12.033
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 10000.0 nM 10.1016/j.ejmech.2013.04.052
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 15000.0 nM 10.1016/j.bmc.2017.03.009
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 15000.0 nM 10.1016/j.bmc.2017.12.033
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 15000.0 nM 10.1021/acs.jmedchem.7b00332
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase EC50 15020.0 nM 10.1021/acsmedchemlett.8b00054
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ED50 0.15 uM 10.1021/jm00025a010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ED50 0.176 uM 10.1021/jm990095j
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ED50 5.0 uM 10.1021/jm990095j
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Fold increase 100.0 None 10.1021/jm040071z
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 9e-05 ug.mL-1 10.1016/j.bmc.2011.01.024
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 0.00011 ug.mL-1 10.1016/j.bmc.2011.01.024
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 0.37 ug.mL-1 10.1016/j.bmc.2010.05.036
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1.3 nM 10.1021/jm990095j
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1.9 nM 10.1016/j.ejmech.2019.05.011
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 50.0 nM 10.1128/aac.00749-06
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 60.0 nM 10.1016/j.bmcl.2006.02.049
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 60.0 nM 10.1016/s0960-894x(98)00369-2
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 73.0 nM 10.1021/jm00041a023
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 73.0 nM 10.1021/jm00054a009
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 80.0 nM 10.1021/jm00024a010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 80.0 nM 10.1021/jm00024a011
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 80.0 nM 10.1021/jm9707028
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 80.0 nM 10.1021/jm9707030
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 84.0 nM 10.1016/0960-894X(94)00478-X
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 84.0 nM 10.1016/j.bmcl.2007.11.114
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 84.0 nM 10.1016/j.bmcl.2007.12.015
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 84.0 nM 10.1021/acs.jmedchem.8b00843
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 84.0 nM 10.1021/jm00008a019
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 84.0 nM 10.1021/jm000255n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 84.0 nM 10.1021/jm00111a045
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 100.0 nM 10.1021/acs.jmedchem.6b00730
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 105.0 nM 10.1021/acsmedchemlett.8b00549
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 110.0 nM 10.1021/jm00024a010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 114.0 nM 10.1021/jm990095j
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 125.0 nM 10.1021/acs.jmedchem.5b01979
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 130.0 nM 10.1021/jm00024a010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 130.0 nM 10.1021/jm990095j
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 137.0 nM 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 160.0 nM 10.1016/j.bmcl.2016.06.065
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 170.0 nM 10.1016/s0960-894x(98)00369-2
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 176.0 nM 10.1016/j.ejmech.2018.01.016
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 180.0 nM 10.1016/j.bmc.2008.06.012
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 180.0 nM 10.1016/j.bmc.2009.06.068
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 180.0 nM 10.1016/j.bmc.2009.12.059
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 180.0 nM 10.1016/j.bmcl.2007.01.025
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 180.0 nM 10.1016/s0960-894x(98)00369-2
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 181.0 nM 10.1021/acs.jmedchem.9b01769
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 200.0 nM 10.1016/s0960-894x(98)00249-2
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 200.0 nM 10.1021/acs.jmedchem.1c01104
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 200.0 nM 10.1021/jm00025a010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 200.0 nM 10.1021/jm0009437
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 200.0 nM 10.1021/jm950639r
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 230.0 nM 10.1021/jm030255y
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 250.0 nM 10.1016/j.bmcl.2004.04.008
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 250.0 nM 10.1016/j.ejmech.2010.10.020
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 250.0 nM 10.1016/S0960-894X(97)00340-5
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 270.0 nM 10.1021/jm960802y
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 280.0 nM 10.1021/jm00076a005
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 300.0 nM 10.1021/jm010853h
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 300.0 nM 10.1021/jm040071z
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 300.0 nM 10.1021/jm980260f
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 320.0 nM 10.1016/j.ejmech.2019.111874
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 320.0 nM 10.1021/jm960158n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 320.0 nM 10.1021/jm990383f
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 323.0 nM 10.1016/j.bmcl.2018.10.010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 400.0 nM 10.1016/j.bmcl.2011.05.020
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 400.0 nM 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 400.0 nM 10.1016/j.ejmech.2020.112696
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 400.0 nM 10.1021/acs.jmedchem.6b01906
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 400.0 nM 10.1021/jm300477h
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 400.0 nM 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 404.0 nM 10.1016/j.ejmech.2019.111603
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 404.0 nM 10.1021/acs.jmedchem.9b01446
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 430.0 nM 10.1021/jm00058a009
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 430.0 nM 10.1021/jm00069a011
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 450.0 nM 10.1074/jbc.m608274200
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 480.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 500.0 nM 10.1007/s00044-007-9004-0
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 500.0 nM 10.1016/j.ejmech.2021.113681
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 500.0 nM 10.1021/jm950702c
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 510.0 nM 10.1016/j.bmcl.2013.10.059
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 510.0 nM 10.1021/acs.jmedchem.1c00268
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 550.0 nM 10.1016/j.bmc.2014.02.029
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 552.0 nM 10.1021/acs.jmedchem.2c00468
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 570.0 nM 10.1021/acsmedchemlett.9b00623
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 575.0 nM 10.1016/j.ejmech.2021.113204
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 580.0 nM 10.1016/j.ejmech.2015.01.042
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 580.0 nM 10.1021/acs.jmedchem.1c00128
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 580.0 nM 10.1021/acs.jmedchem.1c00708
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 580.0 nM 10.1021/acs.jmedchem.1c01676
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 588.84 nM 10.1021/acs.jmedchem.8b01729
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 590.0 nM 10.1016/j.ejmech.2019.111619
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 590.0 nM 10.1021/acsmedchemlett.8b00054
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 595.0 nM 10.1016/j.bmc.2018.12.039
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 595.0 nM 10.1021/acs.jmedchem.8b01729
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 600.0 nM 10.1021/jm950568w
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 620.0 nM 10.1016/j.bmc.2015.03.037
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 620.0 nM 10.1016/j.ejmech.2014.09.054
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 625.0 nM 10.1021/jm990095j
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 630.0 nM 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 640.0 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 645.65 nM 10.1016/j.ejmech.2020.113051
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 670.0 nM 10.1016/j.bmc.2011.05.062
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 670.0 nM 10.1016/j.bmc.2013.10.033
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 700.0 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 705.0 nM 10.1016/j.ejmech.2022.114512
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 778.0 nM 10.1021/acs.jmedchem.1c01015
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 807.0 nM 10.1016/j.bmc.2015.06.048
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 860.0 nM 10.1016/j.bmcl.2006.02.049
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 900.0 nM 10.1016/j.bmc.2014.08.001
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 900.0 nM 10.1016/j.bmc.2018.03.003
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 900.0 nM 10.1074/jbc.m608274200
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 910.0 nM 10.1016/j.bmc.2016.04.010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 920.0 nM 10.1016/j.bmc.2016.04.018
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1000.0 nM 10.1016/j.bmc.2014.11.032
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1060.0 nM 10.1021/acsmedchemlett.0c00612
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1130.0 nM 10.1016/j.bmc.2017.05.040
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1150.0 nM 10.1016/j.bmc.2015.01.002
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1200.0 nM 10.1016/j.bmc.2012.12.049
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1300.0 nM 10.1016/s0960-894x(98)00369-2
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1350.0 nM 10.1016/j.bmc.2014.07.018
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1350.0 nM 10.1016/j.ejmech.2016.05.054
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1390.0 nM 10.1021/acsmedchemlett.7b00361
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1480.0 nM 10.1021/jm9707030
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1528.0 nM 10.1016/j.bmc.2015.09.020
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1550.0 nM 10.1016/j.bmc.2017.05.040
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1550.0 nM 10.1016/j.bmc.2017.12.033
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1550.0 nM 10.1016/j.bmc.2020.115431
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1650.0 nM 10.1016/j.ejmech.2015.08.007
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1700.0 nM 10.1016/j.bmc.2013.09.051
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1700.0 nM 10.1021/jm0613121
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1700.0 nM 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1780.0 nM 10.1016/j.bmc.2013.08.040
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1780.0 nM 10.1016/j.bmc.2014.02.030
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1780.0 nM 10.1039/C3MD00247K
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1795.0 nM 10.1016/j.ejmech.2015.04.050
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1850.0 nM 10.1021/jm9707030
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1900.0 nM 10.1021/jm00024a010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1900.0 nM 10.1021/jm9707028
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2000.0 nM 10.1016/j.bmcl.2011.05.020
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2000.0 nM 10.1128/aac.00749-06
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2110.0 nM 10.1016/S0960-894X(00)80468-0
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2320.0 nM 10.1016/j.ejmech.2017.07.012
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2320.0 nM 10.1021/acsmedchemlett.7b00524
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2400.0 nM 10.1016/j.ejmech.2015.02.022
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2500.0 nM 10.1016/j.bmc.2014.01.054
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2500.0 nM 10.1016/j.ejmech.2007.01.003
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2550.0 nM 10.1016/j.bmc.2013.12.045
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2600.0 nM 10.1021/jm00024a010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2600.0 nM 10.1021/jm00024a011
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2700.0 nM 10.1016/j.bmc.2012.09.058
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2700.0 nM 10.1016/j.bmcl.2012.09.062
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2740.0 nM 10.1016/j.ejmech.2012.02.019
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2740.0 nM 10.1016/j.ejmech.2013.04.052
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2740.0 nM 10.1039/C3MD00028A
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 3000.0 nM 10.1016/j.bmcl.2004.12.030
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 3100.0 nM 10.1021/jm960158n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 3100.0 nM 10.1021/jm990383f
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 3200.0 nM 10.1016/s0960-894x(98)00369-2
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 3200.0 nM 10.1128/aac.01795-09
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 3500.0 nM 10.1021/jm950568w
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 3930.0 nM 10.1021/jm9707030
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4000.0 nM 10.1016/j.bmc.2009.12.059
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4100.0 nM 10.1128/aac.01795-09
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4120.0 nM 10.1016/j.bmc.2010.03.025
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4120.0 nM 10.1016/j.bmcl.2009.04.051
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4120.0 nM 10.1021/jm201506e
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4390.0 nM 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4400.0 nM 10.1016/j.bmc.2011.05.024
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4450.0 nM 10.1021/jm400102x
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4650.0 nM 10.1016/j.bmc.2014.11.012
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4848.0 nM 10.1016/s0960-894x(99)00672-1
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 4848.0 nM 10.1021/jm990580e
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 5000.0 nM 10.1074/jbc.m608274200
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 5500.0 nM 10.1021/jm00062a027
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 5750.0 nM 10.1016/j.bmcl.2006.02.049
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 6000.0 nM 10.1021/jm0209984
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 6200.0 nM 10.1016/j.bmc.2013.09.009
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 6440.0 nM 10.1016/S0960-894X(00)80468-0
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 6440.0 nM 10.1021/jm9508088
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 6650.0 nM 10.1016/j.bmcl.2006.02.049
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7000.0 nM 10.1016/j.bmc.2009.12.059
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7000.0 nM 10.1016/j.bmcl.2011.05.020
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7000.0 nM 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7000.0 nM 10.1016/j.ejmech.2020.112696
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7000.0 nM 10.1021/acs.jmedchem.6b01906
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7000.0 nM 10.1021/jm050257d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7000.0 nM 10.1021/jm300477h
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7000.0 nM 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7200.0 nM 10.1039/C3MD00036B
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7200.0 nM 10.1039/C3MD00225J
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 7500.0 nM 10.1021/np3006887
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 8780.0 nM 10.1016/j.bmc.2016.07.041
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 8800.0 nM 10.1016/j.ejmech.2015.11.039
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 8800.0 nM 10.1016/j.ejmech.2016.02.068
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 8900.0 nM 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 9000.0 nM 10.1016/j.bmcl.2011.05.020
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 9000.0 nM 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 9000.0 nM 10.1021/jm050257d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 9000.0 nM 10.1021/jm300477h
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 9000.0 nM 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 9300.0 nM 10.1128/aac.01559-08
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 10000.0 nM 10.1021/jm050257d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 10600.0 nM 10.1016/j.bmc.2007.07.058
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 11000.0 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 11800.0 nM 10.1021/jm950639r
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 12000.0 nM 10.1128/aac.00749-06
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 13000.0 nM 10.1016/s0960-894x(98)00249-2
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 13200.0 nM 10.1016/j.ejmech.2010.05.070
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 14000.0 nM 10.1016/j.bmc.2016.04.010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 14000.0 nM 10.1016/j.bmc.2017.05.040
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 18000.0 nM 10.1021/jm050257d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 20000.0 nM 10.1021/acs.jmedchem.6b01906
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 20000.0 nM 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 20000.0 nM 10.1021/jm950568w
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 23000.0 nM 10.1016/j.ejmech.2007.01.003
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 23000.0 nM 10.1016/s0960-894x(00)00398-x
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 23000.0 nM 10.1016/s0960-894x(99)00235-8
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 23000.0 nM 10.1016/s0960-894x(99)00460-6
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 23000.0 nM 10.1016/s0960-894x(99)00624-1
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 30000.0 nM 10.1016/j.bmc.2009.12.059
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 31000.0 nM 10.1021/acs.jmedchem.1c01885
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 36000.0 nM 10.1021/jm050257d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 60000.0 nM 10.1021/jm960158n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 67000.0 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 100000.0 nM 10.1016/s0960-894x(01)00011-7
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 100000.0 nM 10.1021/jm040071z
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 100000.0 nM 10.1021/jm800473d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 156000.0 nM 10.1128/aac.01795-09
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 160000.0 nM 10.1016/s0960-894x(98)00249-2
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 185000.0 nM 10.1128/aac.01795-09
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 188000.0 nM 10.1016/j.bmc.2017.05.040
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 201000.0 nM 10.1021/jm950639r
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 240000.0 nM 10.1016/j.bmc.2016.04.010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 269900.0 nM 10.1016/j.bmc.2016.05.010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 273000.0 nM 10.1039/C3MD00036B
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 273000.0 nM 10.1039/C3MD00225J
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 375000.0 nM 10.1016/j.bmc.2016.04.010
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 375000.0 nM 10.1016/j.bmc.2017.05.040
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 1000000.0 nM 10.1128/aac.00800-09
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2000000.0 nM 10.1039/C3MD00036B
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 2000000.0 nM 10.1039/C3MD00225J
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 nan None 10.1016/j.ejmech.2022.114563
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 nan None 10.1021/jm060103d
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 nan None 10.1021/jm070382k
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC50 nan None 10.1021/jm5011622
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase IC90 100.0 nM 10.1021/jm990580e
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 0.3 uM 10.1021/jm050273a
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 0.4 uM 10.1016/j.bmcl.2006.03.080
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 0.4 uM 10.1021/jm050273a
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 0.4 uM 10.1021/jm050744t
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 0.4 uM 10.1021/jm500284x
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 0.4 uM 10.1021/jm800340w
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 0.4 uM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 7.0 uM 10.1021/jm050273a
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 7.0 uM 10.1021/jm500284x
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 7.0 uM 10.1021/jm800340w
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 8.0 uM 10.1016/j.bmcl.2006.03.080
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 8.0 uM 10.1021/jm050744t
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 8.0 uM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 9.0 uM 10.1021/jm050273a
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 9.0 uM 10.1021/jm500284x
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 9.0 uM 10.1021/jm800340w
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 18.0 uM 10.1021/jm050273a
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 20.0 uM 10.1016/j.bmcl.2006.03.080
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 20.0 uM 10.1021/jm050744t
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 20.0 uM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 35.0 uM 10.1021/jm500284x
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 35.0 uM 10.1021/jm800340w
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 36.0 uM 10.1021/jm050273a
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 400.0 nM 10.1021/acs.jmedchem.8b01238
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 400.0 nM 10.1021/jm070488f
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 400.0 nM 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 400.0 nM 10.1021/jm201308v
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 6800.0 nM 10.1021/acs.jmedchem.8b01238
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 7000.0 nM 10.1021/jm070488f
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 7000.0 nM 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 7000.0 nM 10.1021/jm201308v
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 8500.0 nM 10.1021/acs.jmedchem.8b01238
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 9000.0 nM 10.1021/jm070488f
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 9000.0 nM 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 18000.0 nM 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 20000.0 nM 10.1021/jm070488f
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 33000.0 nM 10.1021/acs.jmedchem.8b01238
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 35000.0 nM 10.1021/jm101626c
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 35000.0 nM 10.1021/jm201308v
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase ID50 nan None 10.1021/jm201308v
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 10.0 % 10.1039/C3MD00225J
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 48.0 % 10.1039/C3MD00225J
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 59.0 % 10.1021/jm00024a011
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 75.0 % 10.1128/aac.00749-06
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 84.91 % 10.1016/j.bmc.2022.116612
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 85.0 % 10.1021/jm00024a011
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 85.0 % 10.1039/C3MD00225J
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 92.0 % 10.1016/j.bmc.2010.03.030
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 93.0 % 10.1021/jm00062a027
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 95.5 % 10.1016/j.bmc.2010.01.023
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 95.5 % 10.1016/j.ejmech.2011.01.016
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 99.2 % 10.1016/j.bmc.2011.09.018
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 99.6 % 10.1016/j.bmcl.2014.12.062
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 99.9 % 10.1016/j.ejmech.2015.07.021
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 99.92 % 10.1007/s00044-012-0463-6
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 99.92 % 10.1016/j.bmc.2012.02.037
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 100.0 % 10.1016/j.ejmech.2007.12.015
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition 100.0 % 10.1021/jm00111a045
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition nan % 10.1016/j.ejmech.2019.111699
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Inhibition nan % 10.1021/acsmedchemlett.8b00054
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 300.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 400.0 nM 10.1021/jm0010365
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 400.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 400.0 nM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 400.0 nM 10.1021/jm801395v
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 400.0 nM 10.1021/jm990150o
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 500.0 nM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 4000.0 nM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 5000.0 nM 10.1021/jm801330n
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 7000.0 nM 10.1021/jm0010365
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 7000.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 7000.0 nM 10.1021/jm801395v
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 7000.0 nM 10.1021/jm990150o
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 7200.0 nM 10.1016/j.bmc.2012.12.027
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 9000.0 nM 10.1021/jm0010365
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 9000.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 9000.0 nM 10.1021/jm801395v
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 9000.0 nM 10.1021/jm990150o
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 10000.0 nM 10.1021/jm0010365
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 10000.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 10000.0 nM 10.1021/jm990150o
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 18000.0 nM 10.1021/jm0010365
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 18000.0 nM 10.1021/jm070811e
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 18000.0 nM 10.1021/jm990150o
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 36000.0 nM 10.1021/jm0010365
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 36000.0 nM 10.1021/jm801395v
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 36000.0 nM 10.1021/jm990150o
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 273000.0 nM 10.1016/j.bmc.2012.12.027
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 1000000.0 nM 10.1016/j.bmc.2011.08.025
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 1655000.0 nM 10.1016/j.bmc.2011.08.025
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 1685000.0 nM 10.1016/j.bmc.2011.08.025
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki 2000000.0 nM 10.1016/j.bmc.2012.12.027
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ki nan nM 10.1016/s0960-894x(00)00398-x
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Ratio IC50 nan None 10.1021/acs.jmedchem.1c01104
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Selectivity index 800.0 None 10.1016/j.bmcl.2004.04.008
Human immunodeficiency virus 1 Protease IC50 nan None 10.1016/j.ejmech.2010.05.070
Human immunodeficiency virus 1 Reverse transcriptase EC50 168.0 nM 10.1016/j.ejmech.2021.113204
Human immunodeficiency virus 1 Reverse transcriptase EC50 622.0 nM 10.1016/j.ejmech.2021.113204
Human immunodeficiency virus 1 Reverse transcriptase EC50 1201.7 nM 10.1016/j.ejmech.2020.112549
Human immunodeficiency virus 1 Reverse transcriptase EC50 3154.3 nM 10.1016/j.ejmech.2020.112549
Human immunodeficiency virus 1 Reverse transcriptase EC50 3922.0 nM 10.1016/j.ejmech.2021.113204
Human immunodeficiency virus 1 Reverse transcriptase EC50 4694.0 nM 10.1016/j.ejmech.2020.112549
Human immunodeficiency virus 1 Reverse transcriptase EC50 6496.4 nM 10.1016/j.ejmech.2020.112549
Human immunodeficiency virus 1 Reverse transcriptase EC50 8041.0 nM 10.1016/j.ejmech.2021.113204
Human immunodeficiency virus 1 Reverse transcriptase EC50 9074.0 nM 10.1016/j.ejmech.2021.113204
Human immunodeficiency virus 1 Reverse transcriptase EC50 2441000.0 nM 10.1016/j.ejmech.2020.112549
Human immunodeficiency virus 1 Reverse transcriptase IC50 860.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Reverse transcriptase IC50 7130.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Reverse transcriptase IC50 67600.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Reverse transcriptase IC50 244100.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 1 Reverse transcriptase IC50 357000.0 nM 10.1016/j.ejmech.2021.113868
Human immunodeficiency virus 2 Human immunodeficiency virus 2 Activity nan None 10.1016/j.bmcl.2007.11.114
Human immunodeficiency virus 2 Human immunodeficiency virus 2 Activity nan None 10.1016/j.bmcl.2007.12.015
Human immunodeficiency virus 2 Human immunodeficiency virus 2 Activity nan None 10.1016/j.ejmech.2007.12.015
Human immunodeficiency virus 2 Human immunodeficiency virus 2 Activity nan None 10.1021/jm070382k
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 2.0 ug.mL-1 10.1021/jm100093p
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 4.0 ug.mL-1 10.1007/s00044-011-9662-9
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 4.0 ug.mL-1 10.1007/s00044-011-9664-7
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 4.0 ug.mL-1 10.1007/s00044-011-9705-2
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 4.0 ug.mL-1 10.1007/s00044-011-9776-0
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 4.0 ug.mL-1 10.1039/d2md00076h
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 4000.0 nM 10.1016/j.bmcl.2015.01.058
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 10000.0 nM 10.1016/j.ejmech.2014.04.027
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 10000.0 nM 10.1021/jm101614j
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 10000.0 nM 10.1021/jm5011622
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 15000.0 nM 10.1016/j.bmc.2014.07.018
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 15000.0 nM 10.1016/j.ejmech.2011.08.011
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 15000.0 nM 10.1016/j.ejmech.2012.04.004
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 15000.0 nM 10.1021/acs.jmedchem.1c01015
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 15000.0 nM 10.1021/acs.jmedchem.5b01183
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 15000.0 nM 10.1021/acs.jnatprod.5b00116
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 15020.0 nM 10.1016/j.bmc.2011.10.002
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 15020.0 nM 10.1016/j.ejmech.2013.04.052
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 31250.0 nM 10.1128/aac.00986-09
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 50000.0 nM 10.1016/j.ejmech.2007.01.003
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 50000.0 nM 10.1016/j.ejmech.2008.02.039
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.bmc.2012.12.049
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.bmc.2013.08.040
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.bmc.2013.09.051
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.bmc.2014.01.054
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.bmc.2014.02.030
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.bmc.2014.03.020
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.bmc.2014.11.032
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.bmc.2015.09.020
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.ejmech.2008.09.013
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.ejmech.2014.09.054
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.ejmech.2015.08.007
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.ejmech.2017.02.047
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.ejmech.2022.114563
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1039/C3MD00247K
Human immunodeficiency virus 2 Human immunodeficiency virus 2 IC50 4.0 ug.mL-1 10.1007/s00044-013-0567-7
Human immunodeficiency virus 2 Human immunodeficiency virus 2 IC50 15000.0 nM 10.1016/j.bmc.2010.06.067
Human immunodeficiency virus 2 Human immunodeficiency virus 2 IC50 15000.0 nM 10.1021/np500271u
Human immunodeficiency virus 2 Human immunodeficiency virus type 2 pol protein IC50 20000.0 nM 10.1021/jm950568w
Human T-cell leukemia virus type I Human T-cell leukemia virus type I IC50 nan None 10.1016/j.bmc.2011.01.024
Klebsiella pneumoniae Klebsiella pneumoniae Inhibition 10.08 % 10.6019/CHEMBL4513141
Leishmania infantum Leishmania infantum IC50 64000.0 nM 10.1016/j.bmc.2014.08.005
Mus musculus Glutathione S-transferase Mu 1 Ratio 1200.0 None 10.1021/jm960802y
Mus musculus Hepatocyte Activity 52.6 % 10.1021/acs.jmedchem.9b01990
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Nakaseomyces glabratus Nakaseomyces glabratus IZ nan None 10.1007/s00044-012-0143-6
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Pichia kudriavzevii Pichia kudriavzevii IZ nan None 10.1007/s00044-012-0143-6
Plasmodium falciparum Plasmodium falciparum IC50 64000.0 nM 10.1016/j.bmc.2014.08.005
Porcine endogenous retrovirus Porcine endogenous retrovirus EC50 100000.0 nM 10.1128/aac.00212-07
Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition 42.2 % 10.6019/CHEMBL4513141
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Plasma Fu 0.32 None 10.1021/jm901371v
Rattus norvegicus Plasma t1/2 nan None 10.1016/j.ejmech.2008.09.013
Rattus norvegicus Plasma t1/2 nan None 10.1021/jm070382k
Rattus norvegicus Rattus norvegicus ALB 40300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 41300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 42300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 44000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 260.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 280.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 286.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 300.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 343.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 356.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 49.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 50.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 55.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 63.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 74.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 78.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 82.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 83.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 84.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 87.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 123.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 103.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 130.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 141.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 153.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 160.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 163.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 98.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 98.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 101.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 686.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 743.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 765.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 853.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 893.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 179.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 227.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 248.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 403.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 489.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 578.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 27670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 28330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 29670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 31330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 33670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 34330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.9 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 4.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 29.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 37.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1323.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1360.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1426.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1440.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1450.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1510.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 32.53 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.55 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.7 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.87 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.9 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.08 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 125300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 131000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 132000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 134700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 140700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 65.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 98.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 107.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 133.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 139.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 142.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 12.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 15.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 4383.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 5735.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 5766.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 8345.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 8681.17 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 12359.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 83.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 91.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 92.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 92.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 94.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.7 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.9 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.92 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.43 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.47 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 25.83 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 387000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 389300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 389800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 390700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 392000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 398000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 60.4 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.22 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.8 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.7 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.78 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.77 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 11.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 26.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 79.83 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 88.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 122.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 5.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 6.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 7.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 16.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 340.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 443.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 689.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 725.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 847.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 905.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 105.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 108.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 108.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 108.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 128.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 673670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1001170.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1104000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1202170.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1219000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1370670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.63 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.07 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.38 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.75 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 50300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 57000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 59000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 59800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5220000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5280000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5420000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5490000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5580000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5750000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.17 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.67 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 144.43 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 145.7 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 146.23 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 147.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 3.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 6.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 6.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 8.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 10.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 14.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 5300.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 6130.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 6270.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 9100.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 9450.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13370.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Voltage-gated N-type calcium channel alpha-1B subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Salmonella Salmonella MIC 4.0 ug.mL-1 10.1128/aac.01583-08
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition -36.16 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 13.05 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 16.23 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.1032 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -0.03 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.01 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.18 % 10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition index 0.3233 None 10.1101/2020.04.03.023846
Shigella flexneri Shigella flexneri MIC 4.0 ug.mL-1 10.1128/aac.01583-08
Shigella sonnei Shigella sonnei MIC 4.0 ug.mL-1 10.1128/aac.01583-08
Staphylococcus aureus Staphylococcus aureus Inhibition 12.92 % 10.6019/CHEMBL4513141
Staphylococcus aureus Staphylococcus aureus IZ nan None 10.1007/s00044-012-0143-6
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.01583-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01583-08
Trichomonas vaginalis Trichomonas vaginalis MIC nan None 10.1016/j.ejmech.2015.07.021
Trypanosoma brucei brucei Trypanosoma brucei brucei IC50 64000.0 nM 10.1016/j.bmc.2014.08.005
Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 64000.0 nM 10.1016/j.bmc.2014.08.005
Trypanosoma cruzi Trypanosoma cruzi IC50 64000.0 nM 10.1016/j.bmc.2014.08.005
None ADMET Activity nan None 10.1073/pnas.0704212104
None ADMET Biotransformation nan None 10.1038/s41586-019-1291-3
None ADMET CC50 2.0 ug.mL-1 10.1021/jm100093p
None ADMET CC50 20.06 ug.mL-1 10.1016/j.bmc.2011.01.024
None ADMET CC50 76.13 ug.mL-1 10.1016/j.bmc.2011.09.018
None ADMET CC50 10000.0 nM 10.1016/j.bmc.2011.05.062
None ADMET CC50 10000.0 nM 10.1016/j.bmcl.2006.09.047
None ADMET CC50 10000.0 nM 10.1016/j.bmcl.2011.12.090
None ADMET CC50 10000.0 nM 10.1016/j.bmcl.2012.01.133
None ADMET CC50 10000.0 nM 10.1016/j.bmcl.2012.10.134
None ADMET CC50 10000.0 nM 10.1016/j.bmcl.2014.10.007
None ADMET CC50 10000.0 nM 10.1021/jm00062a027
None ADMET CC50 10000.0 nM 10.1021/ml300146q
None ADMET CC50 10500.0 nM 10.1016/s0960-894x(99)00624-1
None ADMET CC50 15020.0 nM 10.1016/j.bmc.2021.116531
None ADMET CC50 20000.0 nM 10.1021/jm040838n
None ADMET CC50 50000.0 nM 10.1016/j.bmc.2014.08.005
None ADMET CC50 76130.0 nM 10.1016/j.bmc.2014.04.018
None ADMET CC50 100000.0 nM 10.1016/j.bmc.2016.04.018
None ADMET CC50 100000.0 nM 10.1128/aac.00212-07
None ADMET CC50 100000.0 nM 10.1128/aac.01064-10
None ADMET CC50 204003.0 nM 10.1016/j.bmc.2014.11.012
None ADMET CC50 204003.0 nM 10.1021/jm400102x
None ADMET CC50 nan None 10.1021/acs.jmedchem.5b01979
None ADMET CL 1e-06 mL.min-1.g-1 10.1124/dmd.111.039180
None ADMET CL 0.013 uL/min 10.1124/dmd.111.039180
None ADMET CL 0.3 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET Cp 16.0 uM 10.1021/acs.jmedchem.9b01990
None ADMET delta logD nan None 10.1021/jm0000564
None ADMET Drug metabolism 1.3 uM 10.1021/acs.jmedchem.9b01990
None ADMET Drug metabolism nan None 10.1021/acs.jmedchem.9b01990
None ADMET Drug uptake 1385.0 ng/ml 10.1128/aac.01523-08
None ADMET Drug uptake 1538.0 ng/ml 10.1128/aac.01523-08
None ADMET Drug uptake 2595.0 ng/ml 10.1128/aac.01523-08
None ADMET Drug uptake nan None 10.1128/aac.01064-10
None ADMET EC50 49.43 nM 10.1016/j.bmcl.2010.12.003
None ADMET F 80.0 % 10.1021/jm0000564
None ADMET F 95.0 % 10.1021/acs.jmedchem.8b00843
None ADMET IC50 34.0 nM 10.1016/s0960-894x(00)00398-x
None ADMET IC50 34.0 nM 10.1016/s0960-894x(99)00235-8
None ADMET IC50 34.0 nM 10.1016/s0960-894x(99)00460-6
None ADMET IC50 34.0 nM 10.1016/s0960-894x(99)00624-1
None ADMET IC50 5000.0 nM 10.1016/s0960-894x(99)00235-8
None ADMET IC50 5000.0 nM 10.1016/s0960-894x(99)00460-6
None ADMET IC50 5000.0 nM 10.1016/s0960-894x(99)00624-1
None ADMET IC50 64000.0 nM 10.1016/j.bmc.2014.08.005
None ADMET IC50 100000.0 nM 10.1016/s0960-894x(99)00235-8
None ADMET IC50 100000.0 nM 10.1016/s0960-894x(99)00460-6
None ADMET IC50 100000.0 nM 10.1016/s0960-894x(99)00624-1
None ADMET IC50 nan nM 10.1016/s0960-894x(01)00011-7
None ADMET logPapp -4.52 None 10.1124/dmd.111.041665
None ADMET MRT 81.0 hr 10.1124/dmd.108.020479
None ADMET PPB 44.27 % 10.6019/CHEMBL3301361
None ADMET Ratio 0.53 None 10.1128/aac.01523-08
None ADMET Ratio 0.59 None 10.1128/aac.01523-08
None ADMET Ratio CC50/EC50 1.0 None 10.1021/acs.jmedchem.1c01015
None ADMET Ratio CC50/EC50 2.0 None 10.1021/acs.jmedchem.1c00128
None ADMET Ratio CC50/EC50 4.0 None 10.1021/acs.jmedchem.1c00128
None ADMET Ratio CC50/EC50 7.0 None 10.1021/acs.jmedchem.1c01015
None ADMET Ratio CC50/EC50 52.0 None 10.1021/acs.jmedchem.1c00128
None ADMET Ratio CC50/EC50 53.0 None 10.1016/j.ejmech.2020.113063
None ADMET Ratio CC50/EC50 58.0 None 10.1021/acs.jmedchem.8b01238
None ADMET Ratio CC50/EC50 66.0 None 10.1016/j.bmcl.2014.10.007
None ADMET Ratio CC50/EC50 72.0 None 10.1021/acs.jmedchem.1c00128
None ADMET Ratio CC50/EC50 72.0 None 10.1021/acs.jmedchem.1c01676
None ADMET Ratio CC50/EC50 82.0 None 10.1021/acs.jmedchem.1c01015
None ADMET Ratio CC50/EC50 91.0 None 10.1016/j.ejmech.2022.114512
None ADMET Ratio CC50/EC50 92.0 None 10.1021/acs.jmedchem.2c00468
None ADMET Ratio CC50/EC50 94.0 None 10.1016/j.bmc.2021.116531
None ADMET Ratio CC50/EC50 94.0 None 10.1016/j.ejmech.2022.114471
None ADMET Ratio CC50/EC50 113.0 None 10.1016/j.ejmech.2020.113063
None ADMET Ratio CC50/EC50 168.0 None 10.1039/C3MD00028A
None ADMET Ratio CC50/EC50 737.0 None 10.1021/acs.jmedchem.1c01015
None ADMET Ratio CC50/EC50 800.0 None 10.1016/j.ejmech.2008.09.013
None ADMET Ratio CC50/IC50 1.0 None 10.1021/acs.jmedchem.1c01015
None ADMET Ratio CC50/IC50 2.6 None 10.1016/j.ejmech.2019.111714
None ADMET Ratio CC50/IC50 4.3 None 10.1016/j.ejmech.2019.111714
None ADMET Ratio CC50/IC50 51.0 None 10.1021/acs.jmedchem.1c01015
None ADMET Ratio CC50/IC50 1990.0 None 10.1016/j.ejmech.2019.111714
None ADMET Ratio CC50/IC50 5278.0 None 10.1016/j.ejmech.2019.111714
None ADMET Selectivity Index 69.0 None 10.1016/j.ejmech.2021.113868
None ADMET Selectivity Index 72.0 None 10.1021/acs.jmedchem.1c00708
None ADMET Selectivity Index 94.0 None 10.1016/j.bmc.2021.116239
None ADMET T1/2 25.0 hr 10.1021/acs.jmedchem.8b00843
None ADMET T1/2 53.0 hr 10.1124/dmd.108.020479
None ADMET TC50 20000.0 nM 10.1021/jm070488f
None ADMET TI 1.0 None 10.1016/j.bmc.2017.03.061
None ADMET TI 2.01 None 10.1016/j.bmc.2017.03.061
None ADMET TI 143.0 None 10.1016/j.bmc.2017.03.061
None ADMET TI 167.0 None 10.1016/j.bmc.2017.03.061
None ADMET TI 250.0 None 10.1016/j.bmc.2017.03.061
None ADMET TI 333.0 None 10.1016/j.bmc.2017.03.061
None ADMET Vdss 1.3 L.kg-1 10.1124/dmd.108.020479
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value 27.5 None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 5.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value 41.2 None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 6.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value 34.4 None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity LTKB_BD DILI severity score 8.0 None 10.1016/j.drudis.2011.05.007
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value 68.7 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value 55.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Lymphocyte Selectivity index 1111.0 None 10.1021/jm0512490
None Lymphocyte TC50 100.0 uM 10.1021/jm0512490
None NON-PROTEIN TARGET CC50 4.0 ug.mL-1 10.1016/j.bmc.2016.08.029
None NON-PROTEIN TARGET CC50 4.0 ug.mL-1 10.1016/j.ejmech.2016.05.017
None NON-PROTEIN TARGET CC50 10000.0 nM 10.1021/jm990383f
None NON-PROTEIN TARGET CC50 10500.0 nM 10.1016/s0960-894x(99)00460-6
None NON-PROTEIN TARGET CC50 15000.0 nM 10.1016/j.ejmech.2016.05.054
None NON-PROTEIN TARGET CC50 15020.0 nM 10.1021/acs.jmedchem.6b00738
None NON-PROTEIN TARGET EC50 0.05 ug.mL-1 10.1016/j.ejmech.2016.05.017
None NON-PROTEIN TARGET EC50 4.0 ug.mL-1 10.1016/j.ejmech.2016.05.017
None NON-PROTEIN TARGET EC50 250.0 nM 10.1021/acs.jmedchem.6b00738
None NON-PROTEIN TARGET EC50 271.0 nM 10.1021/acs.jmedchem.6b00738
None NON-PROTEIN TARGET EC50 290.0 nM 10.1016/j.ejmech.2016.05.054
None NON-PROTEIN TARGET EC50 2107.0 nM 10.1021/acs.jmedchem.6b00738
None NON-PROTEIN TARGET EC50 5392.0 nM 10.1021/acs.jmedchem.6b00738
None NON-PROTEIN TARGET EC50 7590.0 nM 10.1021/acs.jmedchem.6b00738
None NON-PROTEIN TARGET EC50 9800.0 nM 10.1016/j.ejmech.2016.05.054
None NON-PROTEIN TARGET EC50 15000.0 nM 10.1021/acs.jmedchem.5b01183
None NON-PROTEIN TARGET EC50 15021.0 nM 10.1021/acs.jmedchem.6b00738
None NON-PROTEIN TARGET ED50 0.01 uM 10.1021/jm990383f
None NON-PROTEIN TARGET Fu 0.32 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 37.5 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 18.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 47.1 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC50 0.05 ug.mL-1 10.1016/j.bmc.2016.08.029
None NON-PROTEIN TARGET IC50 4.0 ug.mL-1 10.1016/j.bmc.2016.08.029
None NON-PROTEIN TARGET IC50 31.0 nM 10.1016/j.ejmech.2016.07.047
None NON-PROTEIN TARGET IC50 2800.0 nM 10.1016/j.ejmech.2016.07.047
None NON-PROTEIN TARGET IC50 5000.0 nM 10.1016/j.ejmech.2016.07.047
None NON-PROTEIN TARGET IC50 5480.0 nM 10.1016/j.ejmech.2016.07.047
None NON-PROTEIN TARGET IC50 10000.0 nM 10.1016/j.ejmech.2016.07.047
None NON-PROTEIN TARGET IC50 16100.0 nM 10.1016/j.ejmech.2016.07.047
None NON-PROTEIN TARGET IC50 66700.0 nM 10.1016/j.ejmech.2016.07.047
None NON-PROTEIN TARGET IC90 37.0 nM 10.1016/s0960-894x(99)00672-1
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.01583-08
None NON-PROTEIN TARGET Potency 0.6 nM None
None NON-PROTEIN TARGET Potency 6.7 nM None
None NON-PROTEIN TARGET Potency 11.9 nM None
None NON-PROTEIN TARGET Potency 265.9 nM None
None NON-PROTEIN TARGET Ratio CC50/EC50 80.0 None 10.1016/j.bmc.2016.05.010
None NON-PROTEIN TARGET Ratio CC50/EC50 nan None 10.1016/j.bmc.2016.05.010
None No relevant target LogD 1.81 None 10.1124/dmd.111.041665
None No relevant target LogD 1.92 None 10.1021/jm0000564
None No relevant target LogP 2.05 None 10.1021/acs.jmedchem.8b00843
None No relevant target Log S -3.19 None 10.1016/s0960-894x(00)00172-4
None No relevant target logS0 -3.19 None 10.1021/jm701587d
None No relevant target pKa nan None 10.1021/jm0000564
None No relevant target solubility nan None 10.1016/j.ejmech.2016.05.054
None No relevant target Solubility 167.0 ug.mL-1 10.1016/j.bmc.2016.07.039
None No relevant target Solubility 167.0 ug.mL-1 10.1016/j.bmcl.2013.06.091
None No relevant target Solubility 167.0 ug.mL-1 10.1016/j.bmcl.2019.06.047
None No relevant target Solubility 167.0 ug.mL-1 10.1021/acs.jmedchem.8b01729
None Unchecked Ac50 0.5623 uM None
None Unchecked Ac50 0.7079 uM None
None Unchecked Ac50 1.0 uM None
None Unchecked Ac50 12.59 uM None
None Unchecked Ac50 28.18 uM None
None Unchecked AC50 562.3 nM None
None Unchecked AC50 710.0 nM None
None Unchecked AC50 1000.0 nM None
None Unchecked AC50 12589.3 nM None
None Unchecked AC50 28183.8 nM None
None Unchecked Activity 47.5 % 10.1021/jm800473d
None Unchecked Activity 256.0 uM 10.1128/aac.00749-06
None Unchecked Activity nan None 10.1016/j.bmc.2021.116239
None Unchecked Activity nan None 10.1016/s0960-894x(01)00011-7
None Unchecked Activity nan None 10.1021/acs.jmedchem.6b00730
None Unchecked Activity nan None 10.1021/jm0613121
None Unchecked Activity nan None 10.1021/jm800473d
None Unchecked CC50 300000.0 nM 10.1016/s0960-894x(99)00664-2
None Unchecked Drug metabolism nan None 10.1021/acs.jmedchem.9b01990
None Unchecked EC50 6.7 nM 10.1016/j.ejmech.2019.111987
None Unchecked EC50 161.5 nM 10.1016/j.ejmech.2020.112549
None Unchecked EC50 210.0 nM 10.1016/j.bmc.2017.03.009
None Unchecked EC50 288.4 nM 10.1021/acs.jmedchem.1c00128
None Unchecked EC50 3116.8 nM 10.1016/j.ejmech.2020.112549
None Unchecked EC50 5053.0 nM 10.1016/j.ejmech.2021.113204
None Unchecked EC50 12880.2 nM 10.1016/j.ejmech.2020.112549
None Unchecked EC50 15020.0 nM 10.1016/j.ejmech.2021.113204
None Unchecked FC 2.0 None 10.1021/acs.jmedchem.6b00730
None Unchecked Fold resistance 81.0 None 10.1021/jm010853h
None Unchecked FR 0.6 None 10.1016/s0960-894x(01)00510-8
None Unchecked FR 2.1 None 10.1016/s0960-894x(01)00510-8
None Unchecked FR 5.0 None 10.1016/s0960-894x(01)00510-8
None Unchecked FR 12.7 None 10.1016/s0960-894x(01)00510-8
None Unchecked Hepatotoxicity (acute) 49.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 2.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 29.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 14.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 0.2663 ug.mL-1 10.1016/j.bmc.2011.01.024
None Unchecked IC50 91.0 nM 10.1016/j.bmcl.2016.05.082
None Unchecked IC50 130.0 nM 10.1016/j.ejmech.2019.111987
None Unchecked IC50 180.0 nM 10.1016/j.bmc.2017.03.061
None Unchecked IC50 200.0 nM 10.1021/acs.jmedchem.7b00179
None Unchecked IC50 309.0 nM 10.1016/j.bmcl.2012.12.049
None Unchecked IC50 400.0 nM 10.1021/jm050257d
None Unchecked IC50 826.1 nM 10.1016/j.ejmech.2020.112549
None Unchecked IC50 980.0 nM 10.1016/j.ejmech.2020.112071
None Unchecked IC50 1390.0 nM 10.1016/j.ejmech.2017.02.047
None Unchecked IC50 1620.0 nM 10.1016/j.bmc.2016.05.010
None Unchecked IC50 2100.0 nM 10.1016/j.ejmech.2016.07.047
None Unchecked IC50 2320.0 nM 10.1021/acs.jmedchem.6b00738
None Unchecked IC50 2800.0 nM 10.1016/j.ejmech.2016.10.009
None Unchecked IC50 20000.0 nM 10.1016/j.ejmech.2014.04.027
None Unchecked IC50 20000.0 nM 10.1016/j.ejmech.2020.112696
None Unchecked IC50 67000.0 nM 10.1128/aac.00800-09
None Unchecked IC50 77200.0 nM 10.1021/jm0613121
None Unchecked IC50 100000.0 nM 10.1021/jm0613121
None Unchecked IC50 200000.0 nM 10.1021/acs.jmedchem.6b00730
None Unchecked IC50 375000.0 nM 10.1016/j.bmc.2016.04.010
None Unchecked IC50 1000000.0 nM 10.1128/aac.00800-09
None Unchecked IC50 2000000.0 nM 10.1039/C3MD00225J
None Unchecked IC50 nan None 10.1016/j.bmc.2016.05.010
None Unchecked IC50 nan None 10.1016/j.bmcl.2007.11.114
None Unchecked IC50 nan None 10.1016/j.ejmech.2020.112071
None Unchecked IC50 nan None 10.1021/acs.jmedchem.6b01906
None Unchecked IC50 nan None 10.1021/jm0613121
None Unchecked IC50 nan None None
None Unchecked Inhibition 10.0 % 10.1039/C3MD00225J
None Unchecked Inhibition 50.0 % 10.1016/j.ejmech.2019.111987
None Unchecked Inhibition 88.0 % 10.1016/j.bmc.2017.06.022
None Unchecked Inhibition 91.0 % 10.1016/j.ejmech.2019.111987
None Unchecked Inhibition 97.91 % 10.1016/j.ejmech.2012.07.018
None Unchecked Inhibition 98.0 % 10.1016/j.ejmech.2019.111987
None Unchecked Inhibition 99.2 % 10.1016/j.bmc.2014.04.018
None Unchecked Ki 2000.0 nM 10.1021/jm801395v
None Unchecked Ki 4200.0 nM 10.1016/j.bmc.2011.08.025
None Unchecked Ki 10000.0 nM 10.1021/jm801395v
None Unchecked Ki 18000.0 nM 10.1021/jm801395v
None Unchecked Ki 35000.0 nM 10.1021/jm070811e
None Unchecked Ki 61000.0 nM 10.1016/j.bmc.2011.08.025
None Unchecked Ki 482000.0 nM 10.1016/j.bmc.2011.08.025
None Unchecked Ki 1000000.0 nM 10.1016/j.bmc.2011.08.025
None Unchecked Ki 1362000.0 nM 10.1016/j.bmc.2011.08.025
None Unchecked Ki 2000000.0 nM 10.1016/j.bmc.2012.12.027
None Unchecked Ki nan None None
None Unchecked MEC nan None 10.1016/j.ejmech.2015.07.021
None Unchecked Potency 7307.8 nM None
None Unchecked Ratio 0.6 None 10.1021/jm800473d
None Unchecked Ratio 17.0 None 10.1021/acs.jmedchem.8b01238
None Unchecked Ratio 17.0 None 10.1021/jm101626c
None Unchecked Ratio 17.0 None 10.1021/jm500284x
None Unchecked Ratio 17.0 None 10.1021/jm800340w
None Unchecked Ratio 20.0 None 10.1021/jm201308v
None Unchecked Ratio 21.0 None 10.1021/acs.jmedchem.8b01238
None Unchecked Ratio 22.0 None 10.1021/jm500284x
None Unchecked Ratio 22.0 None 10.1021/jm800340w
None Unchecked Ratio 45.0 None 10.1021/jm101626c
None Unchecked Ratio 81.0 None 10.1021/jm0309856
None Unchecked Ratio 82.0 None 10.1021/acs.jmedchem.8b01238
None Unchecked Ratio 87.0 None 10.1021/jm101626c
None Unchecked Ratio 87.0 None 10.1021/jm201308v
None Unchecked Ratio 87.0 None 10.1021/jm500284x
None Unchecked Ratio 87.0 None 10.1021/jm800340w
None Unchecked Ratio 270.0 None 10.1021/jm031147e
None Unchecked Ratio 800.0 None 10.1016/S0960-894X(97)00340-5
None Unchecked Ratio CC50/EC50 1.0 None 10.1016/j.bmc.2011.08.025
None Unchecked Ratio CC50/EC50 1.0 None 10.1016/j.bmc.2012.04.030
None Unchecked Ratio CC50/EC50 1.0 None 10.1016/j.bmc.2014.08.001
None Unchecked Ratio CC50/EC50 1.0 None 10.1016/j.bmcl.2012.09.062
None Unchecked Ratio CC50/EC50 1.0 None 10.1016/j.bmcl.2018.03.012
None Unchecked Ratio CC50/EC50 1.0 None 10.1016/j.ejmech.2016.05.017
None Unchecked Ratio CC50/EC50 1.0 None 10.1016/j.ejmech.2019.111874
None Unchecked Ratio CC50/EC50 1.0 None 10.1021/acs.jmedchem.5b01183
None Unchecked Ratio CC50/EC50 1.0 None 10.1021/acs.jmedchem.6b00738
None Unchecked Ratio CC50/EC50 1.0 None 10.1021/acs.jmedchem.8b01729
None Unchecked Ratio CC50/EC50 2.0 None 10.1016/j.bmc.2016.07.041
None Unchecked Ratio CC50/EC50 2.0 None 10.1016/j.ejmech.2015.01.042
None Unchecked Ratio CC50/EC50 2.0 None 10.1016/j.ejmech.2016.05.054
None Unchecked Ratio CC50/EC50 2.0 None 10.1016/j.ejmech.2018.03.059
None Unchecked Ratio CC50/EC50 2.0 None 10.1021/acs.jmedchem.6b00738
None Unchecked Ratio CC50/EC50 3.0 None 10.1016/j.ejmech.2016.10.009
None Unchecked Ratio CC50/EC50 3.0 None 10.1021/acs.jmedchem.6b00738
None Unchecked Ratio CC50/EC50 3.0 None 10.1021/acs.jmedchem.7b00332
None Unchecked Ratio CC50/EC50 4.0 None 10.1016/j.bmc.2014.01.054
None Unchecked Ratio CC50/EC50 4.0 None 10.1016/j.ejmech.2014.02.047
None Unchecked Ratio CC50/EC50 4.0 None 10.1016/j.ejmech.2016.10.009
None Unchecked Ratio CC50/EC50 5.0 None 10.1016/j.ejmech.2014.07.104
None Unchecked Ratio CC50/EC50 6.0 None 10.1016/j.bmcl.2013.10.059
None Unchecked Ratio CC50/EC50 7.0 None 10.1016/j.ejmech.2016.10.009
None Unchecked Ratio CC50/EC50 7.0 None 10.1021/acs.jmedchem.6b00738
None Unchecked Ratio CC50/EC50 7.0 None 10.1021/acs.jmedchem.7b00332
None Unchecked Ratio CC50/EC50 13.0 None 10.1021/jm300477h
None Unchecked Ratio CC50/EC50 14.0 None 10.1016/j.ejmech.2014.07.104
None Unchecked Ratio CC50/EC50 15.02 None 10.1016/j.ejmech.2015.11.039
None Unchecked Ratio CC50/EC50 18.0 None 10.1016/j.bmc.2016.07.041
None Unchecked Ratio CC50/EC50 18.0 None 10.1016/j.ejmech.2018.03.059
None Unchecked Ratio CC50/EC50 20.0 None 10.1021/jm400102x
None Unchecked Ratio CC50/EC50 21.0 None 10.1016/j.ejmech.2016.10.009
None Unchecked Ratio CC50/EC50 32.0 None 10.1021/jm400102x
None Unchecked Ratio CC50/EC50 34.0 None 10.1016/j.bmcl.2018.03.012
None Unchecked Ratio CC50/EC50 35.0 None 10.1021/jm201506e
None Unchecked Ratio CC50/EC50 39.0 None 10.1016/j.bmcl.2018.10.010
None Unchecked Ratio CC50/EC50 39.0 None 10.1016/j.ejmech.2019.111619
None Unchecked Ratio CC50/EC50 48.0 None 10.1016/j.bmc.2014.11.032
None Unchecked Ratio CC50/EC50 48.0 None 10.1016/j.bmc.2015.09.020
None Unchecked Ratio CC50/EC50 48.0 None 10.1016/j.ejmech.2014.09.054
None Unchecked Ratio CC50/EC50 48.0 None 10.1016/j.ejmech.2015.01.042
None Unchecked Ratio CC50/EC50 48.0 None 10.1016/j.ejmech.2015.08.007
None Unchecked Ratio CC50/EC50 48.08 None 10.1021/acs.jmedchem.6b00738
None Unchecked Ratio CC50/EC50 50.0 None 10.1016/j.bmc.2015.01.002
None Unchecked Ratio CC50/EC50 51.0 None 10.1016/j.ejmech.2016.05.054
None Unchecked Ratio CC50/EC50 51.0 None 10.1016/j.ejmech.2019.111603
None Unchecked Ratio CC50/EC50 51.0 None 10.1021/acs.jmedchem.9b01446
None Unchecked Ratio CC50/EC50 53.0 None 10.1016/j.ejmech.2016.02.068
None Unchecked Ratio CC50/EC50 53.0 None 10.1021/acsmedchemlett.8b00054
None Unchecked Ratio CC50/EC50 54.0 None 10.1021/jm800340w
None Unchecked Ratio CC50/EC50 55.0 None 10.1021/acs.jmedchem.6b00738
None Unchecked Ratio CC50/EC50 55.0 None 10.1021/acs.jmedchem.7b00332
None Unchecked Ratio CC50/EC50 57.0 None 10.1016/j.bmc.2016.04.010
None Unchecked Ratio CC50/EC50 57.15 None 10.1021/jm101626c
None Unchecked Ratio CC50/EC50 58.0 None 10.1016/j.bmc.2016.07.041
None Unchecked Ratio CC50/EC50 58.0 None 10.1016/j.ejmech.2015.11.039
None Unchecked Ratio CC50/EC50 58.0 None 10.1016/j.ejmech.2017.02.047
None Unchecked Ratio CC50/EC50 58.0 None 10.1016/j.ejmech.2018.03.059
None Unchecked Ratio CC50/EC50 58.0 None 10.1016/j.ejmech.2020.112237
None Unchecked Ratio CC50/EC50 58.0 None 10.1021/jm201308v
None Unchecked Ratio CC50/EC50 60.0 None 10.1016/j.ejmech.2017.07.012
None Unchecked Ratio CC50/EC50 60.0 None 10.1021/acs.jmedchem.5b01183
None Unchecked Ratio CC50/EC50 60.0 None 10.1021/acs.jmedchem.7b00332
None Unchecked Ratio CC50/EC50 61.0 None 10.1016/j.bmc.2015.03.037
None Unchecked Ratio CC50/EC50 62.0 None 10.1021/acs.jmedchem.8b01729
None Unchecked Ratio CC50/EC50 62.0 None 10.1021/jm500284x
None Unchecked Ratio CC50/EC50 64.0 None 10.1016/j.bmc.2016.07.041
None Unchecked Ratio CC50/EC50 64.0 None 10.1016/j.ejmech.2018.03.059
None Unchecked Ratio CC50/EC50 64.0 None 10.1016/j.ejmech.2019.111874
None Unchecked Ratio CC50/EC50 67.0 None 10.1016/j.ejmech.2014.02.047
None Unchecked Ratio CC50/EC50 72.0 None 10.1007/s00044-009-9220-x
None Unchecked Ratio CC50/EC50 72.0 None 10.1016/j.bmc.2009.07.028
None Unchecked Ratio CC50/EC50 72.0 None 10.1016/j.bmc.2011.05.024
None Unchecked Ratio CC50/EC50 72.0 None 10.1016/j.bmc.2011.10.002
None Unchecked Ratio CC50/EC50 72.0 None 10.1016/j.bmc.2017.03.009
None Unchecked Ratio CC50/EC50 72.0 None 10.1016/j.bmcl.2008.09.055
None Unchecked Ratio CC50/EC50 72.0 None 10.1016/j.ejmech.2009.06.037
None Unchecked Ratio CC50/EC50 72.0 None 10.1016/j.ejmech.2012.04.004
None Unchecked Ratio CC50/EC50 75.0 None 10.1016/j.bmc.2010.03.007
None Unchecked Ratio CC50/EC50 75.0 None 10.1016/j.bmc.2012.04.030
None Unchecked Ratio CC50/EC50 75.0 None 10.1016/j.bmc.2012.07.026
None Unchecked Ratio CC50/EC50 75.0 None 10.1016/j.bmc.2012.12.049
None Unchecked Ratio CC50/EC50 75.0 None 10.1016/j.bmcl.2012.09.062
None Unchecked Ratio CC50/EC50 79.0 None 10.1016/j.bmc.2013.12.045
None Unchecked Ratio CC50/EC50 79.0 None 10.1016/j.bmc.2014.08.001
None Unchecked Ratio CC50/EC50 80.0 None 10.1016/j.ejmech.2011.08.011
None Unchecked Ratio CC50/EC50 80.0 None 10.1016/j.ejmech.2016.05.017
None Unchecked Ratio CC50/EC50 81.0 None 10.1016/j.bmc.2017.05.040
None Unchecked Ratio CC50/EC50 81.0 None 10.1016/j.bmc.2017.12.033
None Unchecked Ratio CC50/EC50 81.0 None 10.1016/j.bmc.2020.115431
None Unchecked Ratio CC50/EC50 83.0 None 10.1016/j.bmc.2011.07.023
None Unchecked Ratio CC50/EC50 83.0 None 10.1016/j.bmc.2014.01.054
None Unchecked Ratio CC50/EC50 87.0 None 10.1021/jm070811e
None Unchecked Ratio CC50/EC50 89.0 None 10.1016/j.bmc.2014.02.029
None Unchecked Ratio CC50/EC50 89.0 None 10.1016/j.bmcl.2013.10.059
None Unchecked Ratio CC50/EC50 92.0 None 10.1016/j.ejmech.2020.112811
None Unchecked Ratio CC50/EC50 93.0 None 10.1016/j.ejmech.2020.112549
None Unchecked Ratio CC50/EC50 95.0 None 10.1016/j.ejmech.2016.10.009
None Unchecked Ratio CC50/EC50 100.0 None 10.1016/j.ejmech.2020.113051
None Unchecked Ratio CC50/EC50 100.0 None 10.1016/j.ejmech.2021.113204
None Unchecked Ratio CC50/EC50 114.0 None 10.1016/j.bmc.2010.05.081
None Unchecked Ratio CC50/EC50 120.0 None 10.1016/j.bmc.2018.03.003
None Unchecked Ratio CC50/EC50 127.0 None 10.1016/j.ejmech.2016.10.009
None Unchecked Ratio CC50/EC50 132.0 None 10.1016/j.ejmech.2013.04.052
None Unchecked Ratio CC50/EC50 132.0 None 10.1039/C3MD00247K
None Unchecked Ratio CC50/EC50 133.0 None 10.1016/j.bmc.2013.09.009
None Unchecked Ratio CC50/EC50 133.0 None 10.1016/j.bmc.2013.09.051
None Unchecked Ratio CC50/EC50 148.0 None 10.1021/acs.jnatprod.5b00116
None Unchecked Ratio CC50/EC50 155.0 None 10.1016/j.ejmech.2012.10.036
None Unchecked Ratio CC50/EC50 163.0 None 10.1016/j.bmc.2014.03.020
None Unchecked Ratio CC50/EC50 167.0 None 10.1016/j.ejmech.2012.04.038
None Unchecked Ratio CC50/EC50 167.0 None 10.1016/j.ejmech.2014.04.027
None Unchecked Ratio CC50/EC50 167.0 None 10.1016/j.ejmech.2020.112696
None Unchecked Ratio CC50/EC50 167.0 None 10.1021/acs.jmedchem.6b01906
None Unchecked Ratio CC50/EC50 167.0 None 10.1021/jm5011622
None Unchecked Ratio CC50/EC50 168.0 None 10.1016/j.bmc.2012.09.058
None Unchecked Ratio CC50/EC50 168.0 None 10.1016/j.ejmech.2012.02.019
None Unchecked Ratio CC50/EC50 168.0 None 10.1016/j.ejmech.2018.01.016
None Unchecked Ratio CC50/EC50 176.0 None 10.1016/j.bmc.2008.11.056
None Unchecked Ratio CC50/EC50 179.0 None 10.1016/j.bmcl.2017.03.009
None Unchecked Ratio CC50/EC50 179.4 None 10.1016/j.bmc.2013.08.040
None Unchecked Ratio CC50/EC50 200.0 None 10.1016/j.bmc.2010.05.036
None Unchecked Ratio CC50/EC50 200.0 None 10.1016/j.bmc.2011.08.025
None Unchecked Ratio CC50/EC50 205.0 None 10.1016/j.bmc.2008.06.012
None Unchecked Ratio CC50/EC50 205.0 None 10.1016/j.bmc.2009.06.068
None Unchecked Ratio CC50/EC50 205.0 None 10.1016/j.bmc.2009.12.059
None Unchecked Ratio CC50/EC50 205.0 None 10.1016/j.bmcl.2007.01.025
None Unchecked Ratio CC50/EC50 250.0 None 10.1021/jm100093p
None Unchecked Ratio CC50/EC50 370.0 None 10.1016/j.ejmech.2007.12.015
None Unchecked Ratio CC50/EC50 400.0 None 10.1016/j.bmc.2012.12.027
None Unchecked Ratio CC50/EC50 417.0 None 10.1016/j.ejmech.2007.01.003
None Unchecked Ratio CC50/EC50 417.0 None 10.1016/j.ejmech.2008.02.039
None Unchecked Ratio CC50/EC50 800.0 None 10.1016/j.bmc.2015.06.016
None Unchecked Ratio CC50/EC50 833.3 None 10.1021/acs.jnatprod.5b00025
None Unchecked Ratio CC50/EC50 949.0 None 10.1016/j.ejmech.2006.11.014
None Unchecked Ratio CC50/EC50 1000.0 None 10.1016/j.ejmech.2007.12.015
None Unchecked Ratio CC50/EC50 1073.0 None 10.1021/jm400102x
None Unchecked Ratio CC50/EC50 1073.7 None 10.1016/j.bmc.2014.11.012
None Unchecked Ratio CC50/EC50 1280.0 None 10.1016/j.bmcl.2014.08.019
None Unchecked Ratio CC50/EC50 1369.0 None 10.1128/aac.01064-10
None Unchecked Ratio CC50/EC50 1522.2 None 10.1016/j.bmc.2011.09.018
None Unchecked Ratio CC50/EC50 1639.0 None 10.1016/j.bmc.2013.06.061
None Unchecked Ratio CC50/EC50 2057.0 None 10.1016/j.bmc.2014.04.018
None Unchecked Ratio CC50/EC50 2564.0 None 10.1021/jm801438e
None Unchecked Ratio CC50/EC50 4781.0 None 10.1021/jm201506e
None Unchecked Ratio CC50/EC50 4781.0 None 10.1021/jm400102x
None Unchecked Ratio CC50/EC50 8000.0 None 10.1128/aac.00986-09
None Unchecked Ratio CC50/EC50 14353.0 None 10.1016/j.ejmech.2019.111987
None Unchecked Ratio CC50/EC50 22767.0 None 10.1016/j.bmc.2007.10.013
None Unchecked Ratio CC50/EC50 33885.71 None 10.1016/j.ejmech.2020.112071
None Unchecked Ratio CC50/EC50 nan None 10.1016/j.bmc.2014.01.054
None Unchecked Ratio CC50/EC50 nan None 10.1016/j.bmcl.2015.01.058
None Unchecked Ratio CC50/EC50 nan None 10.1016/j.ejmech.2020.113051
None Unchecked Ratio CC50/IC50 1.0 None 10.1007/s00044-013-0567-7
None Unchecked Ratio CC50/IC50 1.0 None 10.1016/j.bmc.2016.08.029
None Unchecked Ratio CC50/IC50 80.0 None 10.1007/s00044-012-0129-4
None Unchecked Ratio CC50/IC50 80.0 None 10.1007/s00044-013-0567-7
None Unchecked Ratio CC50/IC50 80.0 None 10.1016/j.bmc.2016.08.029
None Unchecked Ratio CC50/IC50 111.0 None 10.1016/j.bmc.2011.05.062
None Unchecked Ratio CC50/IC50 148.0 None 10.1016/j.bmc.2014.02.030
None Unchecked Ratio CC50/IC50 148.0 None 10.1016/j.ejmech.2014.05.059
None Unchecked Ratio CC50/IC50 148.0 None 10.1021/np500271u
None Unchecked Ratio CC50/IC50 800.0 None 10.1016/j.ejmech.2007.08.001
None Unchecked Ratio CC50/IC50 800.0 None 10.1021/jm061167r
None Unchecked Ratio CC50/IC50 5012.0 None 10.1021/jm900802y
None Unchecked Ratio CC50/IC50 15154.0 None 10.1016/j.bmcl.2010.12.003
None Unchecked Ratio EC50 0.6 None 10.1021/acs.jmedchem.1c01015
None Unchecked Ratio EC50 1.0 None 10.1016/j.ejmech.2022.114512
None Unchecked Ratio EC50 1.2 None 10.1016/j.ejmech.2020.112811
None Unchecked Ratio EC50 2.0 None 10.1016/j.ejmech.2021.113868
None Unchecked Ratio EC50 6.3 None 10.1016/j.ejmech.2020.112811
None Unchecked Ratio EC50 7.5 None 10.1021/acs.jmedchem.1c01015
None Unchecked Ratio EC50 11.0 None 10.1021/jm070811e
None Unchecked Ratio EC50 12.0 None 10.1016/j.ejmech.2021.113868
None Unchecked Ratio EC50 15.0 None 10.1016/j.ejmech.2022.114512
None Unchecked Ratio EC50 17.0 None 10.1016/j.bmcl.2008.09.070
None Unchecked Ratio EC50 23.0 None 10.1021/jm070811e
None Unchecked Ratio EC50 31.1 None 10.1016/j.ejmech.2020.112811
None Unchecked Ratio EC50 32.9 None 10.1016/j.ejmech.2020.112811
None Unchecked Ratio EC50 33.0 None 10.1016/j.ejmech.2021.113868
None Unchecked Ratio EC50 39.0 None 10.1016/j.ejmech.2021.113868
None Unchecked Ratio EC50 40.7 None 10.1016/j.ejmech.2020.112811
None Unchecked Ratio EC50 42.0 None 10.1021/acs.jmedchem.1c01015
None Unchecked Ratio EC50 44.4 None 10.1016/j.ejmech.2020.112071
None Unchecked Ratio EC50 45.0 None 10.1016/j.ejmech.2022.114512
None Unchecked Ratio EC50 46.9 None 10.1016/j.ejmech.2020.112811
None Unchecked Ratio EC50 48.0 None 10.1016/j.ejmech.2022.114512
None Unchecked Ratio EC50 51.1 None 10.1021/acs.jmedchem.1c01015
None Unchecked Ratio EC50 51.21 None 10.1021/jm8003009
None Unchecked Ratio EC50 70.0 None 10.1021/jm070811e
None Unchecked Ratio EC50 81.2 None 10.1016/j.ejmech.2020.112071
None Unchecked Ratio EC50 88.0 None 10.1016/j.ejmech.2022.114512
None Unchecked Ratio EC50 124.0 None 10.1021/jm070811e
None Unchecked Ratio EC50 149.9 None 10.1016/j.ejmech.2020.112071
None Unchecked Ratio EC50 167.0 None 10.1016/j.ejmech.2020.112071
None Unchecked Ratio EC50 848.0 None 10.1016/j.ejmech.2020.112071
None Unchecked Ratio EC50 4657.9 None 10.1016/j.ejmech.2020.112071
None Unchecked Ratio EC50 5000.0 None 10.1016/j.ejmech.2020.112071
None Unchecked Ratio IC50 200.0 None 10.1021/acs.jmedchem.6b00730
None Unchecked Ratio IC50/EC50 250.0 None 10.1016/j.bmc.2015.06.016
None Unchecked Ratio IC50/EC50 525.0 None 10.1016/j.bmc.2015.06.016
None Unchecked Ratio Ki 0.8 None 10.1021/jm070811e
None Unchecked Ratio Ki 15.0 None 10.1016/j.bmc.2011.08.025
None Unchecked Ratio Ki 17.0 None 10.1021/jm070811e
None Unchecked Ratio Ki 22.0 None 10.1021/jm070811e
None Unchecked Ratio Ki 25.0 None 10.1021/jm070811e
None Unchecked Ratio Ki 45.0 None 10.1021/jm070811e
None Unchecked Ratio Ki 87.0 None 10.1021/jm070811e
None Unchecked Ratio Ki 250.0 None 10.1016/j.bmc.2011.08.025
None Unchecked Ratio Ki 395.0 None 10.1016/j.bmc.2011.08.025
None Unchecked Ratio Ki 400.0 None 10.1016/j.bmc.2011.08.025
None Unchecked Ratio Ki 423.0 None 10.1016/j.bmc.2011.08.025
None Unchecked Selectivity 571.0 None 10.1021/jm9901125
None Unchecked Selectivity index 222.0 None 10.1021/jm070488f
None Unchecked Selectivity index 625.0 None 10.1021/jm00094a009
None Unchecked Selectivity index 3973.0 None 10.1021/jm00012a002
None Unchecked Selectivity Index 1.0 None 10.1016/j.ejmech.2015.02.022
None Unchecked Selectivity Index 46.0 None 10.1016/j.bmc.2010.06.067
None Unchecked Selectivity Index 48.0 None 10.1016/j.ejmech.2015.02.022
None Unchecked Selectivity Index 520.0 None 10.1021/jm101614j
None Unchecked Selectivity Index 1438.0 None 10.1016/j.ejmech.2019.111864
None Unchecked Selectivity Index 3300.0 None 10.1021/jm901653e
None Unchecked Selectivity Index 22767.0 None 10.1016/j.bmc.2010.06.067
None Unchecked Selectivity ratio 2.0 None 10.1016/j.ejmech.2019.111987
None Unchecked Selectivity ratio 45.1 None 10.1128/aac.01795-09
None Unchecked Selectivity ratio 48.8 None 10.1128/aac.01795-09
None Unchecked S.I 1000.0 None 10.1016/s0960-894x(99)00664-2
None Unchecked SI 175.0 None 10.1021/jm020949r
None Unchecked SI 263.0 None 10.1021/jm020949r
None Unchecked TC50 10.0 uM 10.1016/j.bmc.2017.03.061

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT014864 Cc1cc(=O)[nH]c2c1NC(=O)c1cccnc1N2C1CC1>>Cc1ccnc2c1NC(=O)c1cccnc1N2C1CC1 MNXR133354