Navigation

name Structure Reference Source Properties Activities Metabolism

4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide

AlkaPlorer ID: AK079983

Synonym: None

IUPAC Name: 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide

Structure

SMILES: CNC(=O)C1=CC(OC2=CC=C(NC(O)=NC3=CC=C(Cl)C(C(F)(F)F)=C3)C=C2)=CC=N1

copy

InChI: InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)

copy

InChIKey: MLDQJTXFUGDVEO-UHFFFAOYSA-N

copy

Reference

PubChem CID: 25222582

CAS: 284461-73-0

NPASS: NPC480220

COCONUT: CNP0272310

Properties Information

Molecule Weight: 464.8310000000001

TPSA？: 95.84

MolLogP？: 5.563300000000004

Number of H-Donors: 3

Number of H-Acceptors: 4

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Chikungunya virus Chikungunya virus EC50 160.0 nM 10.1021/acs.jmedchem.0c01467
Danio rerio Vascular endothelial growth factor receptor 2 IC50 2600.0 nM 10.1021/jm301537p
Eastern equine encephalitis virus Eastern equine encephalitis virus EC50 6700.0 nM 10.1021/acs.jmedchem.0c01467
Enterococcus faecalis Enterococcus faecalis MIC 275370.0 nM 10.1016/j.bmcl.2022.128975
Enterococcus faecium Enterococcus faecium MIC 275370.0 nM 10.1016/j.bmcl.2022.128975
Enterovirus A71 Enterovirus A71 EC50 1500.0 nM 10.1016/j.bmc.2016.05.055
Enterovirus A71 Enterovirus A71 EC50 1500.0 nM 10.1021/acs.jmedchem.0c01467
Enterovirus A71 Enterovirus A71 IC50 1300.0 nM 10.1021/acs.jmedchem.0c01467
Enterovirus A71 Enterovirus A71 IC50 1500.0 nM 10.1021/acs.jmedchem.0c01467
Gallus gallus Chorioallantoic membrane Activity nan None 10.1016/j.bmcl.2019.126711
Gallus gallus Myosin light chain kinase, smooth muscle Kd 10000.0 nM 10.1038/nbt1358
Gallus gallus Tyrosine-protein kinase SRC Activity 44.0 % 10.1042/bj20070797
Hepacivirus hominis Hepatitis C virus EC50 7200.0 nM 10.1021/acs.jmedchem.0c01467
Hepacivirus hominis Hepatitis C virus IC50 7200.0 nM 10.1021/acs.jmedchem.0c01467
Homo sapiens 143B Activity 0.128 None 10.1073/pnas.0707498104
Homo sapiens 26S protease regulatory subunit 6B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Activity 82.0 % 10.1042/bj20070797
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Ki 3981.07 nM None
Homo sapiens 5637 Activity 0.693 None 10.1073/pnas.0707498104
Homo sapiens 639-V Activity 0.995 None 10.1073/pnas.0707498104
Homo sapiens 647-V Activity 0.813 None 10.1073/pnas.0707498104
Homo sapiens 697 IC50 7059.89 nM 10.6019/CHEMBL1201861
Homo sapiens 769-P Activity 1.073 None 10.1073/pnas.0707498104
Homo sapiens 786-0 Activity -46.6 % 10.1021/acs.jmedchem.0c01733
Homo sapiens 786-0 Activity -36.4 % 10.1021/acs.jmedchem.0c01733
Homo sapiens 786-0 Activity -34.9 % 10.1021/acs.jmedchem.0c01733
Homo sapiens 786-0 GI50 3160.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens 786-0 GI50 3160.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens 786-0 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens 786-0 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens 786-0 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens 786-0 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens 786-0 IC50 4900.0 nM 10.1021/acs.jnatprod.7b00698
Homo sapiens 786-0 IC50 4900.0 nM 10.1021/acs.jnatprod.7b01053
Homo sapiens 786-0 IC50 5300.0 nM 10.1021/acs.jnatprod.8b00015
Homo sapiens 786-0 IC50 13000.0 nM 10.1021/acs.jmedchem.9b00598
Homo sapiens 786-0 IC50 15620.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens 786-0 Inhibition 84.5 % 10.1016/j.ejmech.2019.111965
Homo sapiens 786-0 LC50 50100.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens 786-0 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens 786-0 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens 786-0 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens 786-0 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens 786-0 TGI 7620.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens 786-0 TGI 10000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens 8305C Activity 0.874 None 10.1073/pnas.0707498104
Homo sapiens 8505C Activity 0.972 None 10.1073/pnas.0707498104
Homo sapiens 8505C IC50 4700.0 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens 8-MG-BA IC50 136719.58 nM 10.6019/CHEMBL1201861
Homo sapiens A101D IC50 21375.19 nM 10.6019/CHEMBL1201861
Homo sapiens A2058 Activity 1.052 None 10.1073/pnas.0707498104
Homo sapiens A2058 IC50 3800.0 nM 10.1021/np201007a
Homo sapiens A253 cell line IC50 34229.64 nM 10.6019/CHEMBL1201861
Homo sapiens A2780 Activity 0.944 None 10.1073/pnas.0707498104
Homo sapiens A-375 Activity 0.814 None 10.1073/pnas.0707498104
Homo sapiens A-375 GI 44.1 % 10.1016/j.ejmech.2014.11.008
Homo sapiens A-375 IC50 1950.0 nM 10.1016/j.bmc.2020.115897
Homo sapiens A-375 IC50 2200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens A-375 IC50 2400.0 nM 10.1021/jm300613w
Homo sapiens A-375 IC50 3360.0 nM 10.1016/j.bmc.2018.03.038
Homo sapiens A-375 IC50 5400.0 nM 10.1016/j.bmc.2009.12.020
Homo sapiens A-375 IC50 5400.0 nM 10.1016/j.bmcl.2008.04.073
Homo sapiens A-375 IC50 5580.0 nM 10.1016/j.bmcl.2009.05.007
Homo sapiens A-375 IC50 5600.0 nM 10.1016/j.ejmech.2011.04.031
Homo sapiens A-375 IC50 7560.0 nM 10.1016/j.ejmech.2013.10.049
Homo sapiens A-375 IC50 7880.0 nM 10.1016/j.bmc.2019.03.062
Homo sapiens A-375 IC50 8270.0 nM 10.1016/j.ejmech.2018.09.005
Homo sapiens A-375 IC50 8330.0 nM 10.1016/j.ejmech.2018.05.054
Homo sapiens A-375 IC50 9170.0 nM 10.1016/j.ejmech.2014.03.020
Homo sapiens A-375 IC50 10280.0 nM 10.1016/j.bmc.2020.115897
Homo sapiens A-375 IC50 13600.0 nM 10.1016/j.ejmech.2018.11.033
Homo sapiens A-375 IC50 13640.0 nM 10.1016/j.ejmech.2014.10.039
Homo sapiens A-375 IC50 13640.0 nM 10.1016/j.ejmech.2017.02.041
Homo sapiens A-375 IC50 16240.0 nM 10.1016/j.ejmech.2014.11.008
Homo sapiens A-375 T/C 37.35 % 10.1016/j.ejmech.2014.10.039
Homo sapiens A-375 TGI 76.59 % 10.1016/j.ejmech.2014.11.008
Homo sapiens A388 IC50 1591.65 nM 10.6019/CHEMBL1201861
Homo sapiens A3-KAW IC50 1884.2 nM 10.6019/CHEMBL1201861
Homo sapiens A-427 Activity 0.808 None 10.1073/pnas.0707498104
Homo sapiens A-431 Activity 0.977 None 10.1073/pnas.0707498104
Homo sapiens A-431 GI 68.94 % 10.1021/acs.jmedchem.7b01091
Homo sapiens A-431 IC50 120.0 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens A-431 IC50 3320.0 nM 10.1016/j.ejmech.2018.12.067
Homo sapiens A-431 IC50 10460.0 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens A498 GI50 2510.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens A498 GI50 2510.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens A498 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens A498 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens A498 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens A498 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens A498 IC50 405809.57 nM 10.6019/CHEMBL1201861
Homo sapiens A498 IC50 nan None 10.1016/j.ejmech.2018.11.061
Homo sapiens A498 LC50 31600.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens A498 TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens A498 TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens A498 TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens A498 TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens A498 TGI 6310.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens A4-Fuk IC50 9756.1 nM 10.6019/CHEMBL1201861
Homo sapiens A549 Activity 0.7 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 0.9 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 0.989 None 10.1073/pnas.0707498104
Homo sapiens A549 Activity 1.42 % 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 Activity 3.1 % 10.1016/j.ejmech.2018.11.023
Homo sapiens A549 Activity 3.93 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 5.79 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 6.18 % 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 Activity 6.23 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 6.38 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 8.62 % 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 Activity 9.33 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 15.51 % 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 Activity 16.22 % 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 Activity 19.4 % 10.1016/j.ejmech.2018.11.023
Homo sapiens A549 Activity 19.9 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 23.14 % 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 Activity 28.6 % 10.1016/j.ejmech.2011.07.045
Homo sapiens A549 Activity 30.0 % 10.1016/j.ejmech.2018.11.023
Homo sapiens A549 Activity 31.0 % 10.1016/j.ejmech.2018.11.023
Homo sapiens A549 Activity 38.0 % 10.1016/j.ejmech.2018.11.023
Homo sapiens A549 Activity 45.13 % 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 Activity 46.8 % 10.1016/j.ejmech.2018.11.023
Homo sapiens A549 Activity 48.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens A549 Activity 72.8 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 81.99 % 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 Activity 83.7 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 85.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens A549 Activity 90.27 % 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 Activity 92.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens A549 Activity 103.2 % 10.1016/j.ejmech.2011.07.045
Homo sapiens A549 Activity 515.0 pg/ml 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 Activity nan None 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 EC50 1000.0 nM 10.1021/acs.jmedchem.6b00087
Homo sapiens A549 FC 9.0 None 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 GI 81.23 % 10.1016/j.ejmech.2010.02.005
Homo sapiens A549 GI 94.8 % 10.1007/s00044-012-0398-y
Homo sapiens A549 GI nan None 10.1007/s00044-012-0398-y
Homo sapiens A549 GI50 3160.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens A549 GI50 3160.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens A549 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens A549 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens A549 GI50 4100.0 nM 10.1016/j.ejmech.2021.113634
Homo sapiens A549 IC50 3.779 ug.mL-1 10.1016/j.bmcl.2018.01.027
Homo sapiens A549 IC50 80.0 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens A549 IC50 630.0 nM 10.1016/j.bmc.2015.04.071
Homo sapiens A549 IC50 750.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 IC50 1250.0 nM 10.1016/j.ejmech.2020.112946
Homo sapiens A549 IC50 1450.0 nM 10.1016/j.ejmech.2015.08.045
Homo sapiens A549 IC50 1920.0 nM 10.1016/j.ejmech.2014.04.059
Homo sapiens A549 IC50 2020.0 nM 10.1016/j.bmc.2015.12.038
Homo sapiens A549 IC50 2900.0 nM 10.1039/d2md00065b
Homo sapiens A549 IC50 2920.0 nM 10.1016/j.bmc.2017.09.003
Homo sapiens A549 IC50 3100.0 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens A549 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens A549 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens A549 IC50 3190.0 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens A549 IC50 3360.0 nM 10.1039/C3MD00192J
Homo sapiens A549 IC50 3880.0 nM 10.1016/j.ejmech.2018.12.067
Homo sapiens A549 IC50 4000.0 nM 10.1016/j.bmcl.2013.02.034
Homo sapiens A549 IC50 4470.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens A549 IC50 4500.0 nM 10.1016/j.bmc.2012.04.006
Homo sapiens A549 IC50 5000.0 nM 10.1016/j.bmc.2021.116454
Homo sapiens A549 IC50 5130.0 nM 10.1016/j.ejmech.2021.113192
Homo sapiens A549 IC50 5210.0 nM 10.1016/j.ejmech.2010.02.005
Homo sapiens A549 IC50 5231.0 nM 10.1039/C2MD20275A
Homo sapiens A549 IC50 5530.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens A549 IC50 5620.0 nM 10.1016/j.ejmech.2020.112461
Homo sapiens A549 IC50 6080.0 nM 10.1007/s00044-012-0398-y
Homo sapiens A549 IC50 6110.0 nM 10.1016/j.ejmech.2018.11.061
Homo sapiens A549 IC50 6210.0 nM 10.1016/j.ejmech.2018.03.001
Homo sapiens A549 IC50 6530.0 nM 10.1016/j.ejmech.2016.03.033
Homo sapiens A549 IC50 6700.0 nM 10.1016/j.ejmech.2017.08.054
Homo sapiens A549 IC50 6830.0 nM 10.1021/acs.jmedchem.0c01512
Homo sapiens A549 IC50 7430.0 nM 10.1016/j.ejmech.2020.112457
Homo sapiens A549 IC50 7620.0 nM 10.1016/j.ejmech.2019.06.054
Homo sapiens A549 IC50 8100.0 nM 10.1016/j.bmcl.2019.126711
Homo sapiens A549 IC50 10700.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens A549 IC50 12540.0 nM 10.1016/j.ejmech.2013.03.043
Homo sapiens A549 IC50 13640.0 nM 10.1016/j.ejmech.2015.10.045
Homo sapiens A549 IC50 19300.0 nM 10.1039/C8MD00057C
Homo sapiens A549 IC50 25671.0 nM 10.1016/j.bmc.2019.06.001
Homo sapiens A549 IC50 27000.0 nM 10.1016/j.ejmech.2018.11.023
Homo sapiens A549 IC50 27000.0 nM 10.1016/j.ejmech.2019.03.012
Homo sapiens A549 IC50 27710.0 nM 10.1016/j.ejmech.2013.06.055
Homo sapiens A549 IC50 64900.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens A549 IC50 11240000.0 nM 10.1016/j.bmc.2020.115599
Homo sapiens A549 Inhibition 0.0 % 10.1016/j.ejmech.2020.112205
Homo sapiens A549 LC50 63100.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens A549 TGI 7360.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens A549 TGI 7940.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens A549 TGI 7940.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens A549 TGI 7940.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens A549 TGI 7940.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens A549 TGI 12600.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens ABC-1 Activity 0.644 None 10.1073/pnas.0707498104
Homo sapiens ACHN Activity 0.12 g 10.1021/acs.jmedchem.9b00598
Homo sapiens ACHN Activity 0.576 None 10.1073/pnas.0707498104
Homo sapiens ACHN GI50 2510.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens ACHN GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens ACHN GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens ACHN GI50 3160.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens ACHN IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens ACHN IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens ACHN IC50 3300.0 nM 10.1021/acs.jmedchem.9b00598
Homo sapiens ACHN IC50 3400.0 nM 10.1021/acs.jnatprod.7b00698
Homo sapiens ACHN IC50 3400.0 nM 10.1021/acs.jnatprod.7b01053
Homo sapiens ACHN IC50 3500.0 nM 10.1021/acs.jnatprod.8b00015
Homo sapiens ACHN IC50 nan None 10.1021/acs.jmedchem.9b00598
Homo sapiens ACHN LC50 100000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens ACHN TGI 10000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens ACHN TGI 10000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens ACHN TGI 10000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens ACHN TGI 10000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens ACHN TGI 12600.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens ACN IC50 46433.96 nM 10.6019/CHEMBL1201861
Homo sapiens Actin-related protein 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Actin-related protein 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Activin receptor type-1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Activin receptor type-1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Activin receptor type-1 Ki 3981.07 nM None
Homo sapiens Activin receptor type-1B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-1B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-1B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Activin receptor type-1B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Activin receptor type-2A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-2A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-2A Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Activin receptor type-2B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-2B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-2B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Activin receptor type-2B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Acyl-CoA dehydrogenase family member 10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Acyl-CoA dehydrogenase family member 11 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adaptor-associated kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Adaptor-associated kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Adaptor-associated kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Adaptor-associated kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adaptor-associated kinase Kd nan None 10.1038/nbt1068
Homo sapiens Adenine phosphoribosyltransferase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor AC50 1880.1 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adenylate kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ADP/ATP translocase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ADP/ATP translocase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens AGS Activity 0.794 None 10.1073/pnas.0707498104
Homo sapiens ALK tyrosine kinase receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens ALK tyrosine kinase receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens ALK tyrosine kinase receptor Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens ALK tyrosine kinase receptor Ki 6309.57 nM None
Homo sapiens ALL-PO IC50 31.84 nM 10.6019/CHEMBL1201861
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 15020.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-synuclein Potency 8912.5 nM None
Homo sapiens AM-38 IC50 225060.89 nM 10.6019/CHEMBL1201861
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Activity nan None 10.1016/j.bmcl.2013.01.096
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd nan None 10.1038/nbt1068
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Ki 3162.28 nM None
Homo sapiens AMP-activated protein kinase, alpha-2 subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens AMP-activated protein kinase, alpha-2 subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens AMP-activated protein kinase, alpha-2 subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens AMP-activated protein kinase, gamma-1 subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens AMP-activated protein kinase, gamma-2 subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ankyrin repeat and protein kinase domain-containing protein 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ankyrin repeat and protein kinase domain-containing protein 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ankyrin repeat and protein kinase domain-containing protein 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens ARH-77 IC50 186838.39 nM 10.6019/CHEMBL1201861
Homo sapiens ASPC1 Activity 0.808 None 10.1073/pnas.0707498104
Homo sapiens ATN-1 IC50 191795.17 nM 10.6019/CHEMBL1201861
Homo sapiens ATP-binding cassette sub-family G member 2 IC50 3100.0 nM 10.1016/j.ejmech.2022.114346
Homo sapiens ATP-dependent RNA helicase DDX1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ATP-dependent RNA helicase DDX3X Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ATP-dependent RNA helicase DHX30 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens AU565 Activity 0.952 None 10.1073/pnas.0707498104
Homo sapiens BB30-HNC IC50 14060.87 nM 10.6019/CHEMBL1201861
Homo sapiens BB49-HNC IC50 58722.27 nM 10.6019/CHEMBL1201861
Homo sapiens BB65-RCC IC50 470.73 nM 10.6019/CHEMBL1201861
Homo sapiens BC-3 IC50 4233.91 nM 10.6019/CHEMBL1201861
Homo sapiens BCPAP Activity 0.825 None 10.1073/pnas.0707498104
Homo sapiens BCPAP IC50 6700.0 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens Bcr/Abl fusion protein EC50 nan None 10.1021/acs.jmedchem.6b00087
Homo sapiens Bcr/Abl fusion protein GI50 7300.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens BE-13 IC50 2696.09 nM 10.6019/CHEMBL1201861
Homo sapiens Becker IC50 191401.82 nM 10.6019/CHEMBL1201861
Homo sapiens Bel-7402 Activity 0.32 g 10.1021/acs.jmedchem.1c01520
Homo sapiens Bel-7402 Activity 11.6 None 10.1021/acs.jmedchem.1c01520
Homo sapiens Bel-7402 IC50 4200.0 nM 10.1039/d2md00065b
Homo sapiens Bel-7402 IC50 5800.0 nM 10.1016/j.bmcl.2013.02.034
Homo sapiens Bel-7402 IC50 6030.0 nM 10.1016/j.ejmech.2022.114402
Homo sapiens Bel-7402 IC50 10260.0 nM 10.1021/jm1014814
Homo sapiens Bel-7402 IC50 10310.0 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens Bel-7402 IC50 10870.0 nM 10.1016/j.ejmech.2020.112661
Homo sapiens Bel-7402 Inhibition 51.31 % 10.1021/acs.jmedchem.1c01520
Homo sapiens Bel-7402 T/C 45.13 % 10.1021/acs.jmedchem.1c01520
Homo sapiens Bel7402/5-FU IC50 13310.0 nM 10.1016/j.ejmech.2022.114402
Homo sapiens BEL-7404 tumor cell line IC50 92000.0 nM 10.1016/j.ejmech.2018.08.017
Homo sapiens BEN Activity 0.789 None 10.1073/pnas.0707498104
Homo sapiens Beta-1 adrenergic receptor AC50 28000.1 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens BFTC-905 Activity 0.348 None 10.1073/pnas.0707498104
Homo sapiens BFTC-909 Activity 0.632 None 10.1073/pnas.0707498104
Homo sapiens BGC-823 IC50 3000.0 nM 10.1039/d2md00065b
Homo sapiens BGC-823 IC50 10910.0 nM 10.1016/j.bmc.2012.05.051
Homo sapiens BGC-823 IC50 nan None 10.1016/j.ejmech.2022.114376
Homo sapiens BHT-101 Activity 0.806 None 10.1073/pnas.0707498104
Homo sapiens Bile salt export pump AC50 2000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 8000.0 nM 10.1002/hep.27206
Homo sapiens Bile salt export pump IC50 8000.0 nM 10.1093/toxsci/kfq269
Homo sapiens Bile salt export pump IC50 10000.0 nM 10.1124/dmd.112.047068
Homo sapiens BL-41 IC50 134856.47 nM 10.6019/CHEMBL1201861
Homo sapiens BL-70 IC50 200004.73 nM 10.6019/CHEMBL1201861
Homo sapiens BMP-2-inducible protein kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens BMP-2-inducible protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens BMP-2-inducible protein kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens BMP-2-inducible protein kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens BMP-2-inducible protein kinase Kd nan None 10.1038/nbt1068
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Bone morphogenetic protein receptor type-1B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Bone morphogenetic protein receptor type-1B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Bone morphogenetic protein receptor type-1B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens B-raf/RAF proto-oncogene serine/threonine-protein kinase Activity nan None 10.1021/acs.jmedchem.5b01354
Homo sapiens B-raf/RAF proto-oncogene serine/threonine-protein kinase Inhibition nan % 10.1021/acs.jmedchem.5b01354
Homo sapiens Brain glycogen phosphorylase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Breakpoint cluster region protein Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens BR serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens BR serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens BR serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens BR serine/threonine-protein kinase 1 Ki 10000.0 nM None
Homo sapiens BR serine/threonine-protein kinase 2 Activity 80.0 % 10.1042/bj20070797
Homo sapiens BR serine/threonine-protein kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens BR serine/threonine-protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens BR serine/threonine-protein kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens BT-474 Activity 1.048 None 10.1073/pnas.0707498104
Homo sapiens BT-474 IC50 290367.1 nM 10.6019/CHEMBL1201861
Homo sapiens BT-549 Activity 0.974 None 10.1073/pnas.0707498104
Homo sapiens BT-549 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens BT-549 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens BT-549 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens BT-549 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens BT-549 TGI 3980.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens BT-549 TGI 3980.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens BT-549 TGI 3980.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens BT-549 TGI 3980.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens BV-173 IC50 5956.82 nM 10.6019/CHEMBL1201861
Homo sapiens BXPC-3 Activity 0.602 None 10.1073/pnas.0707498104
Homo sapiens C2BBe1 IC50 24323.89 nM 10.6019/CHEMBL1201861
Homo sapiens C32 Activity 1.104 None 10.1073/pnas.0707498104
Homo sapiens C-33-A Activity 0.07 None 10.1073/pnas.0707498104
Homo sapiens C-33-A Activity 0.96 None 10.1073/pnas.0707498104
Homo sapiens C8166 IC50 17683.29 nM 10.6019/CHEMBL1201861
Homo sapiens CA46 IC50 214973.98 nM 10.6019/CHEMBL1201861
Homo sapiens Caco-2 Activity 0.901 None 10.1073/pnas.0707498104
Homo sapiens CAKI-1 Activity 1.067 None 10.1073/pnas.0707498104
Homo sapiens CAKI-1 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens CAKI-1 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens CAKI-1 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens CAKI-1 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens CAKI-1 TGI 12590.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens CAKI-1 TGI 12590.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens CAKI-1 TGI 12590.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens CAKI-1 TGI 12590.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens CAL-120 Activity 1.406 None 10.1073/pnas.0707498104
Homo sapiens CAL-12T Activity 0.744 None 10.1073/pnas.0707498104
Homo sapiens CAL-148 Activity 1.137 None 10.1073/pnas.0707498104
Homo sapiens CAL-148 IC50 119244.26 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-51 Activity 0.979 None 10.1073/pnas.0707498104
Homo sapiens CAL-54 Activity 0.824 None 10.1073/pnas.0707498104
Homo sapiens CAL-62 Activity 0.732 None 10.1073/pnas.0707498104
Homo sapiens CAL-85-1 Activity 1.417 None 10.1073/pnas.0707498104
Homo sapiens Calu-1 Activity 0.994 None 10.1073/pnas.0707498104
Homo sapiens Calu-3 Activity 1.372 None 10.1073/pnas.0707498104
Homo sapiens Calu-6 IC50 13604.59 nM 10.6019/CHEMBL1201861
Homo sapiens CaM kinase I alpha Activity 53.0 % 10.1042/bj20070797
Homo sapiens CaM kinase I alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase I alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase I alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase I alpha Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase I alpha Ki 7943.28 nM None
Homo sapiens CaM kinase I delta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase I delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase I delta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase I delta Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase I delta Ki 2511.89 nM None
Homo sapiens CaM kinase I gamma Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase I gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase I gamma Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase II alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase II alpha Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase II alpha Ki 3981.07 nM None
Homo sapiens CaM kinase II beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II beta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase II beta Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase II beta Ki 3981.07 nM None
Homo sapiens CaM kinase II delta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II delta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase II delta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CaM kinase II delta Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase II delta Ki 6309.57 nM None
Homo sapiens CaM kinase II gamma Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II gamma Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase II gamma Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CaM kinase II gamma Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase II gamma Ki 6309.57 nM None
Homo sapiens CaM kinase IV Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase IV Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase IV Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase IV Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CaM-kinase kinase alpha Activity 97.0 % 10.1042/bj20070797
Homo sapiens CaM-kinase kinase alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM-kinase kinase alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM-kinase kinase alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM-kinase kinase alpha Kd nan None 10.1038/nbt1068
Homo sapiens CaM-kinase kinase beta Activity 88.0 % 10.1042/bj20070797
Homo sapiens CaM-kinase kinase beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM-kinase kinase beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM-kinase kinase beta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM-kinase kinase beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CaM-kinase kinase beta Kd nan None 10.1038/nbt1068
Homo sapiens CaM-kinase kinase beta Ki 2511.89 nM None
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Activity 72.0 % 10.1042/bj20070797
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Ki 2511.89 nM None
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase, gamma catalytic subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase type II-alpha regulatory subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens CAPAN-1 Activity 0.789 None 10.1073/pnas.0707498104
Homo sapiens Capan-2 Activity 1.128 None 10.1073/pnas.0707498104
Homo sapiens CaR-1 Activity 1.191 None 10.1073/pnas.0707498104
Homo sapiens Carbonic anhydrase I Ki 10000.0 nM 10.1016/j.ejmech.2019.111600
Homo sapiens Carbonic anhydrase II Ki 10000.0 nM 10.1016/j.ejmech.2019.111600
Homo sapiens Carbonic anhydrase IX Ki 10000.0 nM 10.1016/j.ejmech.2019.111600
Homo sapiens Carbonic anhydrase VII Ki 8136.4 nM 10.1016/j.ejmech.2019.111600
Homo sapiens CAS-1 IC50 159882.31 nM 10.6019/CHEMBL1201861
Homo sapiens Casein kinase I alpha IC50 250.0 nM 10.1038/nchembio.117
Homo sapiens Casein kinase I alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I alpha Ki 3981.07 nM None
Homo sapiens Casein kinase I delta Activity 99.0 % 10.1042/bj20070797
Homo sapiens Casein kinase I delta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I delta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I delta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I delta Ki 7943.28 nM None
Homo sapiens Casein kinase I epsilon Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I epsilon Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I epsilon Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I epsilon Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I epsilon Kd nan None 10.1038/nbt1068
Homo sapiens Casein kinase I gamma 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I gamma 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I gamma 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I gamma 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I gamma 1 Kd nan None 10.1038/nbt1068
Homo sapiens Casein kinase I gamma 1 Ki 6309.57 nM None
Homo sapiens Casein kinase I gamma 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I gamma 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I gamma 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I gamma 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I gamma 2 Kd nan None 10.1038/nbt1068
Homo sapiens Casein kinase I gamma 2 Ki 7943.28 nM None
Homo sapiens Casein kinase II Activity 95.0 % 10.1042/bj20070797
Homo sapiens Casein kinase II alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase II alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase II alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase II alpha Ki 6309.57 nM None
Homo sapiens Casein kinase II alpha (prime) Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase II alpha (prime) Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase II alpha (prime) Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase II alpha (prime) Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I isoform alpha-like Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I isoform alpha-like Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I isoform gamma-3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I isoform gamma-3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I isoform gamma-3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I isoform gamma-3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CCF-STTG1 Activity 0.645 None 10.1073/pnas.0707498104
Homo sapiens CCRF-CEM GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens CCRF-CEM GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens CCRF-CEM GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens CCRF-CEM GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens CCRF-CEM IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens CCRF-CEM IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens CCRF-CEM IC50 146598.86 nM 10.6019/CHEMBL1201861
Homo sapiens CCRF-CEM LC50 100000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens CCRF-CEM TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens CCRF-CEM TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens CCRF-CEM TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens CCRF-CEM TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens CCRF-CEM TGI 100000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens CDK2/Cyclin A1 IC50 nan None 10.1021/acs.jmedchem.7b01261
Homo sapiens CDK2/Cyclin A2 Kd 8700.0 nM 10.1039/C5MD00462D
Homo sapiens CDK6/cyclin D1 Kd nan None 10.1039/C5MD00462D
Homo sapiens CDK8/Cyclin C IC50 32.5 nM 10.1021/acsmedchemlett.6b00044
Homo sapiens CDK8/Cyclin C IC50 100.0 nM 10.1016/j.ejmech.2021.113634
Homo sapiens CDK8/Cyclin C Inhibition 50.0 % 10.1021/acsmedchemlett.6b00044
Homo sapiens CDK8/Cyclin C Inhibition 100.0 % 10.1016/j.ejmech.2021.113634
Homo sapiens CDK8/Cyclin C Kd 310.0 nM 10.1016/j.ejmech.2018.11.076
Homo sapiens CDK9/Cyclin K Kd nan None 10.1039/C5MD00462D
Homo sapiens CDK9/cyclin T1 Kd nan None 10.1039/C5MD00462D
Homo sapiens Cell division cycle 2-like protein kinase 6 Activity 35.0 % 10.1016/j.ejmech.2020.112443
Homo sapiens Cell division cycle 2-like protein kinase 6 IC50 206.0 nM 10.1021/acs.jmedchem.7b00901
Homo sapiens Cell division cycle 2-like protein kinase 6 Kd 250.0 nM 10.1038/nbt1358
Homo sapiens Cell division cycle 2-like protein kinase 6 Kd 250.0 nM 10.1038/nbt.1990
Homo sapiens Cell division cycle 2-like protein kinase 6 Kd 250.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cell division cycle 7-related protein kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cell division cycle 7-related protein kinase Ki 1258.93 nM None
Homo sapiens Cell division protein kinase 8 Activity 35.0 % 10.1016/j.ejmech.2020.112443
Homo sapiens Cell division protein kinase 8 IC50 30.0 nM 10.1016/j.ejmech.2020.113043
Homo sapiens Cell division protein kinase 8 IC50 36.6 nM 10.1016/j.ejmech.2020.112443
Homo sapiens Cell division protein kinase 8 IC50 71.5 nM 10.1021/acs.jmedchem.2c00820
Homo sapiens Cell division protein kinase 8 IC50 185.4 nM 10.1021/acs.jmedchem.2c01042
Homo sapiens Cell division protein kinase 8 IC50 199.0 nM 10.1021/acs.jmedchem.7b00901
Homo sapiens Cell division protein kinase 8 IC50 1620.0 nM 10.1021/acs.jmedchem.7b00901
Homo sapiens Cell division protein kinase 8 IC50 3400.0 nM 10.1021/acs.jmedchem.2c00820
Homo sapiens Cell division protein kinase 8 IC50 4520.0 nM 10.1021/acs.jmedchem.7b00901
Homo sapiens Cell division protein kinase 8 IC50 10000.0 nM 10.1016/j.ejmech.2020.112443
Homo sapiens Cell division protein kinase 8 Inhibition 69.9 % 10.1021/acs.jmedchem.2c01042
Homo sapiens Cell division protein kinase 8 Inhibition 71.7 % 10.1021/acs.jmedchem.2c00820
Homo sapiens Cell division protein kinase 8 Kd 310.0 nM 10.1038/nbt1358
Homo sapiens Cell division protein kinase 8 Kd 310.0 nM 10.1038/nbt.1990
Homo sapiens Cell division protein kinase 8 Kd 310.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cell division protein kinase 8 Ki 79.43 nM None
Homo sapiens CESS IC50 36284.8 nM 10.6019/CHEMBL1201861
Homo sapiens CFPAC-1 Activity 1.033 None 10.1073/pnas.0707498104
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cGMP-dependent protein kinase 1 beta Ki 1995.26 nM None
Homo sapiens cGMP-dependent protein kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens cGMP-dependent protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens cGMP-dependent protein kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens cGMP-dependent protein kinase 2 Ki 1584.89 nM None
Homo sapiens CGTH-W-1 IC50 250.22 nM 10.6019/CHEMBL1201861
Homo sapiens ChaGo-K-1 Activity 0.915 None 10.1073/pnas.0707498104
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin B receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens CHP-126 IC50 11973.81 nM 10.6019/CHEMBL1201861
Homo sapiens Chromodomain-helicase-DNA-binding protein 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Citron Rho-interacting kinase Kd 6200.0 nM 10.1038/nbt1358
Homo sapiens Citron Rho-interacting kinase Kd 6200.0 nM 10.1038/nbt.1990
Homo sapiens Citron Rho-interacting kinase Kd 6200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Citron Rho-interacting kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 1 Activity 83.0 % 10.1042/bj20070797
Homo sapiens c-Jun N-terminal kinase 1 Inhibition nan % 10.1016/j.bmc.2012.04.006
Homo sapiens c-Jun N-terminal kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens c-Jun N-terminal kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens c-Jun N-terminal kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens c-Jun N-terminal kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 1 Kd nan None 10.1038/nbt1068
Homo sapiens c-Jun N-terminal kinase 1 Ki 3981.07 nM None
Homo sapiens c-Jun N-terminal kinase 2 Activity 65.0 % 10.1042/bj20070797
Homo sapiens c-Jun N-terminal kinase 2 Kd 3600.0 nM 10.1038/nbt1068
Homo sapiens c-Jun N-terminal kinase 2 Kd 7400.0 nM 10.1038/nbt.1990
Homo sapiens c-Jun N-terminal kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens c-Jun N-terminal kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens c-Jun N-terminal kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 2 Ki 3981.07 nM None
Homo sapiens c-Jun N-terminal kinase 3 Activity 101.0 % 10.1042/bj20070797
Homo sapiens c-Jun N-terminal kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens c-Jun N-terminal kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens c-Jun N-terminal kinase 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens c-Jun N-terminal kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 3 Kd nan None 10.1038/nbt1068
Homo sapiens c-Jun N-terminal kinase 3 Ki 3162.28 nM None
Homo sapiens CMK IC50 125211.34 nM 10.6019/CHEMBL1201861
Homo sapiens COLO 205 Activity 1.076 None 10.1073/pnas.0707498104
Homo sapiens COLO 205 GI50 1990.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens COLO 205 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens COLO 205 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens COLO 205 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens COLO 205 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens COLO 205 IC50 3000.0 nM 10.1021/jm500118j
Homo sapiens COLO 205 IC50 7040.0 nM 10.1016/j.ejmech.2017.02.041
Homo sapiens COLO 205 LC50 31600.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens COLO 205 TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens COLO 205 TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens COLO 205 TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens COLO 205 TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens COLO 205 TGI 5010.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens COLO 320 Activity 0.389 None 10.1073/pnas.0707498104
Homo sapiens COLO 320DM Activity 0.52 None 10.1073/pnas.0707498104
Homo sapiens COLO-320-HSR IC50 33160.25 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-668 IC50 145130.16 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-684 IC50 56290.12 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-800 IC50 67298.97 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-824 IC50 173044.36 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-829 IC50 56037.77 nM 10.6019/CHEMBL1201861
Homo sapiens COR-L23 Activity 1.008 None 10.1073/pnas.0707498104
Homo sapiens COR-L279 IC50 18136.15 nM 10.6019/CHEMBL1201861
Homo sapiens COR-L88 IC50 26579.57 nM 10.6019/CHEMBL1201861
Homo sapiens CP66-MEL IC50 39073.29 nM 10.6019/CHEMBL1201861
Homo sapiens CPC-N IC50 657210.26 nM 10.6019/CHEMBL1201861
Homo sapiens CRO-AP2 IC50 124909.57 nM 10.6019/CHEMBL1201861
Homo sapiens CTB-1 IC50 33110.12 nM 10.6019/CHEMBL1201861
Homo sapiens CTV-1 IC50 42840.63 nM 10.6019/CHEMBL1201861
Homo sapiens CW-2 IC50 313731.02 nM 10.6019/CHEMBL1201861
Homo sapiens Cyclin-dependent kinase 1 Inhibition nan % 10.1021/acs.jmedchem.5b01582
Homo sapiens Cyclin-dependent kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 1 Ki 7943.28 nM None
Homo sapiens Cyclin-dependent kinase 12 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 13 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 13 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 2 Kd 8700.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 2 Kd nan None 10.1038/nbt1068
Homo sapiens Cyclin-dependent kinase 2 Ki 7943.28 nM None
Homo sapiens Cyclin-dependent kinase 2/cyclin A Activity 80.0 % 10.1042/bj20070797
Homo sapiens Cyclin-dependent kinase 3 Kd 3800.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 4 IC50 3000.0 nM 10.1021/jm500118j
Homo sapiens Cyclin-dependent kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 4/cyclin D1 IC50 3000.0 nM 10.1021/jm500118j
Homo sapiens Cyclin-dependent kinase 4/cyclin D1 Kd nan None 10.1039/C5MD00462D
Homo sapiens Cyclin-dependent kinase 5 Kd 6200.0 nM 10.1038/nbt1068
Homo sapiens Cyclin-dependent kinase 5 Kd 8300.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 5 Ki 3981.07 nM None
Homo sapiens Cyclin-dependent kinase 6 IC50 130.0 nM 10.1016/j.ejmech.2019.01.003
Homo sapiens Cyclin-dependent kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 7 Kd 140.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 7 Kd 140.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 7 Kd 140.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 7 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 7 Ki 3981.07 nM None
Homo sapiens Cyclin-dependent kinase 9 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 9 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 9 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 9 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 9 Ki 1584.89 nM None
Homo sapiens Cyclin-dependent kinase-like 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 2 Kd 130.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 2 Kd 130.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase-like 3 Kd 490.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 3 Kd 490.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase-like 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase-like 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclooxygenase-2 AC50 4100.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cysteine--tRNA ligase, cytoplasmic Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cytochrome c1, heme protein, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cytochrome P450 3A4 Activity 36.0 % 10.1021/acs.jmedchem.0c02245
Homo sapiens Cytochrome P450 3A4 CL 4.38 uL/min/pmol 10.1021/acs.jmedchem.7b01465
Homo sapiens Cytochrome P450 3A4 IC50 10000.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens D-247MG IC50 2144.8 nM 10.6019/CHEMBL1201861
Homo sapiens D-263MG IC50 253556.33 nM 10.6019/CHEMBL1201861
Homo sapiens D283 Med IC50 75579.34 nM 10.6019/CHEMBL1201861
Homo sapiens D-336MG IC50 118510.2 nM 10.6019/CHEMBL1201861
Homo sapiens D-392MG IC50 7626.63 nM 10.6019/CHEMBL1201861
Homo sapiens D-502MG IC50 94190.56 nM 10.6019/CHEMBL1201861
Homo sapiens D-542MG IC50 22025.57 nM 10.6019/CHEMBL1201861
Homo sapiens DAN-G Activity 0.492 None 10.1073/pnas.0707498104
Homo sapiens Daoy Activity 0.039 None 10.1073/pnas.0707498104
Homo sapiens Daoy Activity 0.04 None 10.1073/pnas.0707498104
Homo sapiens Daoy Activity 0.63 None 10.1073/pnas.0707498104
Homo sapiens Daudi IC50 21930.38 nM 10.6019/CHEMBL1201861
Homo sapiens DB IC50 58904.41 nM 10.6019/CHEMBL1201861
Homo sapiens DBTRG-05MG Activity 0.06 None 10.1073/pnas.0707498104
Homo sapiens DBTRG-05MG Activity 0.88 None 10.1073/pnas.0707498104
Homo sapiens dCTP pyrophosphatase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Death-associated protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Death-associated protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Death-associated protein kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Death-associated protein kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Death-associated protein kinase 2 Kd nan None 10.1038/nbt1068
Homo sapiens Death-associated protein kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Death-associated protein kinase 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Death-associated protein kinase 3 Kd nan None 10.1038/nbt1068
Homo sapiens Death-associated protein kinase 3 Ki 3162.28 nM None
Homo sapiens DEL IC50 12098.47 nM 10.6019/CHEMBL1201861
Homo sapiens Delta(24)-sterol reductase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Deoxycytidine kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DG-75 IC50 43759.51 nM 10.6019/CHEMBL1201861
Homo sapiens Discoidin domain-containing receptor 2 IC50 7.0 nM 10.1021/jm500167q
Homo sapiens Discoidin domain-containing receptor 2 IC50 36.0 nM 10.1021/jm500167q
Homo sapiens Discoidin domain-containing receptor 2 Kd 6.6 nM 10.1021/jm5012319
Homo sapiens Discoidin domain-containing receptor 2 Kd 6.6 nM 10.1038/nbt1358
Homo sapiens Discoidin domain-containing receptor 2 Kd 6.6 nM 10.1038/nbt.1990
Homo sapiens Discoidin domain-containing receptor 2 Kd 6.6 nM 10.1182/blood-2009-05-222034
Homo sapiens Discoidin domain-containing receptor 2 Kd 7.0 nM 10.1021/jm500167q
Homo sapiens Discoidin domain-containing receptor 2 Kd 313.0 nM 10.1021/jm500167q
Homo sapiens Discoidin domain-containing receptor 2 Kd 1950.0 nM 10.1126/science.aan4368
Homo sapiens DJM-1 IC50 24522.08 nM 10.6019/CHEMBL1201861
Homo sapiens DLD-1 Activity 0.704 None 10.1073/pnas.0707498104
Homo sapiens DLD-1 Activity 28.0 % 10.1016/j.ejmech.2011.07.045
Homo sapiens DLD-1 Activity 93.4 % 10.1016/j.ejmech.2011.07.045
Homo sapiens DMS-114 IC50 10544.05 nM 10.6019/CHEMBL1201861
Homo sapiens DMS-153 IC50 24861.39 nM 10.6019/CHEMBL1201861
Homo sapiens DMS-79 IC50 455990.97 nM 10.6019/CHEMBL1201861
Homo sapiens DNA-dependent protein kinase IC50 50000.0 nM 10.1038/nchembio.117
Homo sapiens DnaJ homolog subfamily A member 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DNA replication licensing factor MCM4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DNA topoisomerase II alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DNA topoisomerase II beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DOHH-2 IC50 7056.76 nM 10.6019/CHEMBL1201861
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter AC50 6851.3 nM 10.1038/s41467-023-40064-9
Homo sapiens DSH1 IC50 65315.08 nM 10.6019/CHEMBL1201861
Homo sapiens DU-145 Activity 0.01 None 10.1073/pnas.0707498104
Homo sapiens DU-145 Activity 0.012 None 10.1073/pnas.0707498104
Homo sapiens DU-145 Activity 0.88 None 10.1073/pnas.0707498104
Homo sapiens DU-145 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens DU-145 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens DU-145 IC50 3160.0 nM 10.1016/j.bmc.2020.115897
Homo sapiens DU-145 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens DU-145 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens DU-145 IC50 3160.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens DU-145 IC50 5100.0 nM 10.1021/np201007a
Homo sapiens DU-145 IC50 24910.0 nM 10.1016/j.ejmech.2013.06.055
Homo sapiens DU-145 IC50 83736.0 nM 10.1016/j.bmc.2019.06.001
Homo sapiens DU-145 TGI 7940.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens DU-145 TGI 7940.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens DU-145 TGI 7940.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens DU-145 TGI 7940.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens DU-4475 IC50 23889.69 nM 10.6019/CHEMBL1201861
Homo sapiens Dual serine/threonine and tyrosine protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Activity 74.0 % 10.1042/bj20070797
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Inhibition 37.74 % 10.1016/j.ejmech.2020.113081
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Ki 3162.28 nM None
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Ki 3981.07 nM None
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 5 Kd 190.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase; MEK1/2 Inhibition nan % 10.1016/j.ejmech.2013.06.060
Homo sapiens Dual specificity protein kinase CLK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase CLK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity protein kinase CLK2 Kd nan None 10.1038/nbt1068
Homo sapiens Dual specificity protein kinase CLK2 Ki 3981.07 nM None
Homo sapiens Dual specificity protein kinase CLK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase CLK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity protein kinase CLK3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity protein kinase CLK3 Kd nan None 10.1038/nbt1068
Homo sapiens Dual specificity protein kinase CLK4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase CLK4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity protein kinase CLK4 Kd nan None 10.1038/nbt1068
Homo sapiens Dual specificity protein kinase CLK4 Ki 3162.28 nM None
Homo sapiens Dual specificity protein kinase TTK Kd 3500.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase TTK Kd 3500.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase TTK Kd 3500.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity protein kinase TTK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity protein kinase TTK Kd nan None 10.1038/nbt1068
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity testis-specific protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Activity 82.0 % 10.1042/bj20070797
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kd nan None 10.1039/C5MD00462D
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Ki 1995.26 nM None
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Ki 2511.89 nM None
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 2 Activity 81.0 % 10.1042/bj20070797
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 3 Activity 47.0 % 10.1042/bj20070797
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 3 Ki 1995.26 nM None
Homo sapiens Dual specificty protein kinase CLK1 Kd 7500.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificty protein kinase CLK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificty protein kinase CLK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificty protein kinase CLK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificty protein kinase CLK1 Kd nan None 10.1038/nbt1068
Homo sapiens Dynamin-like 120 kDa protein, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens EA.hy 926 Activity nan None 10.1016/j.ejmech.2018.12.067
Homo sapiens EA.hy 926 IC50 11020.0 nM 10.1016/j.bmc.2022.117115
Homo sapiens EA.hy 926 IC50 11740.0 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens EA.hy 926 IC50 11740.0 nM 10.1016/j.ejmech.2018.12.067
Homo sapiens EA.hy 926 IC50 18520.0 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens EA.hy 926 IC50 24360.0 nM 10.1016/j.ejmech.2016.12.059
Homo sapiens EA.hy 926 IC50 24360.0 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens EB2 IC50 85001.42 nM 10.6019/CHEMBL1201861
Homo sapiens EB-3 IC50 184600.68 nM 10.6019/CHEMBL1201861
Homo sapiens ECC12 IC50 24280.27 nM 10.6019/CHEMBL1201861
Homo sapiens ECC4 IC50 15055.77 nM 10.6019/CHEMBL1201861
Homo sapiens EC-GI-10 IC50 41580.49 nM 10.6019/CHEMBL1201861
Homo sapiens EFM-19 Activity 1.019 None 10.1073/pnas.0707498104
Homo sapiens EFO-21 Activity 0.761 None 10.1073/pnas.0707498104
Homo sapiens EGI-1 Activity 0.49 None 10.1073/pnas.0707498104
Homo sapiens EJ IC50 22900.0 nM 10.1016/j.bmc.2013.11.013
Homo sapiens EKVX GI50 2510.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens EKVX GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens EKVX GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens EKVX IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens EKVX IC50 49662.79 nM 10.6019/CHEMBL1201861
Homo sapiens EKVX LC50 63100.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens EKVX TGI 7940.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens EKVX TGI 19950.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens EKVX TGI 19950.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens EKVX TGI 19950.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens Electron transfer flavoprotein subunit beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Elongation factor Tu, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens EM-2 IC50 1355.78 nM 10.6019/CHEMBL1201861
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens EOL1 IC50 114485.02 nM 10.6019/CHEMBL1201861
Homo sapiens Ephrin type-A receptor 1 Kd 3100.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 1 Kd 3100.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 1 Kd 3100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 2 Kd 2000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 2 Kd 2000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 2 Kd 2000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 2 Kd 4800.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 2 Ki 794.33 nM None
Homo sapiens Ephrin type-A receptor 3 Kd 1900.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 3 Kd 1900.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 3 Kd 1900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 3 Kd 6400.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 4 Kd 1300.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 4 Kd 3000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 4 Kd 3000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 4 Kd 3000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 5 Kd 360.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 5 Kd 360.0 nM 10.1073/pnas.0707498104
Homo sapiens Ephrin type-A receptor 5 Kd 3500.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 6 Kd 240.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 6 Kd 240.0 nM 10.1073/pnas.0707498104
Homo sapiens Ephrin type-A receptor 6 Kd 370.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 6 Kd 370.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 6 Kd 370.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 7 Kd 670.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 7 Kd 670.0 nM 10.1073/pnas.0707498104
Homo sapiens Ephrin type-A receptor 7 Kd 5300.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 7 Kd 5300.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 7 Kd 5300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 7 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 8 Kd 960.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 8 Kd 960.0 nM 10.1073/pnas.0707498104
Homo sapiens Ephrin type-A receptor 8 Kd 2400.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 8 Kd 2400.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 8 Kd 2400.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 1 Kd 1700.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-B receptor 1 Kd 3000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 1 Kd 3000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 1 Kd 3000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 2 Kd 1900.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 2 Kd 1900.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 2 Kd 1900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-B receptor 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-B receptor 4 IC50 0.2 nM 10.1016/j.ejmech.2016.12.059
Homo sapiens Ephrin type-B receptor 4 IC50 0.22 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens Ephrin type-B receptor 4 IC50 0.22 nM 10.1016/j.ejmech.2018.12.067
Homo sapiens Ephrin type-B receptor 4 IC50 4.46 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens Ephrin type-B receptor 4 IC50 4.62 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens Ephrin type-B receptor 4 IC50 1900.0 nM 10.1038/nchembio.117
Homo sapiens Ephrin type-B receptor 4 Inhibition nan % 10.1021/acs.jmedchem.5b01582
Homo sapiens Ephrin type-B receptor 4 Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 4 Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 4 Kd 1800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 4 Kd 3900.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-B receptor 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-B receptor 6 Kd 240.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 6 Kd 240.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Epidermal growth factor receptor IC50 nan None 10.1016/j.bmc.2015.12.001
Homo sapiens Epidermal growth factor receptor erbB1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Epidermal growth factor receptor erbB1 Activity -74.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Epidermal growth factor receptor erbB1 IC50 2.96 nM 10.1016/j.bmc.2015.12.038
Homo sapiens Epidermal growth factor receptor erbB1 IC50 43.5 nM 10.1016/j.bmcl.2019.126711
Homo sapiens Epidermal growth factor receptor erbB1 IC50 56.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens Epidermal growth factor receptor erbB1 IC50 57.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens Epidermal growth factor receptor erbB1 IC50 57.8 nM 10.1016/j.ejmech.2019.06.054
Homo sapiens Epidermal growth factor receptor erbB1 IC50 80.0 nM 10.1016/j.ejmech.2015.12.032
Homo sapiens Epidermal growth factor receptor erbB1 IC50 110.0 nM 10.1016/j.bmcl.2023.129285
Homo sapiens Epidermal growth factor receptor erbB1 IC50 110.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens Epidermal growth factor receptor erbB1 IC50 110.0 nM 10.1016/j.ejmech.2022.114661
Homo sapiens Epidermal growth factor receptor erbB1 IC50 1140.0 nM 10.1016/j.ejmech.2021.113865
Homo sapiens Epidermal growth factor receptor erbB1 IC50 1150.0 nM 10.1016/j.bmcl.2021.128118
Homo sapiens Epidermal growth factor receptor erbB1 IC50 10000.0 nM 10.1039/C3MD00096F
Homo sapiens Epidermal growth factor receptor erbB1 IC50 50000.0 nM 10.1038/nchembio.117
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None 10.1016/j.bmc.2015.12.001
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None 10.1016/j.bmc.2017.09.003
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None 10.1016/j.ejmech.2014.07.099
Homo sapiens Epidermal growth factor receptor erbB1 Inhibition nan % 10.1016/j.bmcl.2015.07.082
Homo sapiens Epidermal growth factor receptor erbB1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Epidermal growth factor receptor erbB1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Epidermal growth factor receptor erbB1 Kd nan None 10.1038/nbt1068
Homo sapiens Epidermal growth factor receptor erbB1 Ki 1995.26 nM None
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 1.5 nM 10.1021/jm5012319
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 1.5 nM 10.1038/nbt1358
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 1.5 nM 10.1038/nbt.1990
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 1.5 nM 10.1182/blood-2009-05-222034
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 1641.0 nM 10.1126/science.aan4368
Homo sapiens EPLC-272H Activity 0.21 None 10.1073/pnas.0707498104
Homo sapiens EPLC-272H Activity 0.211 None 10.1073/pnas.0707498104
Homo sapiens EPLC-272H Activity 0.88 None 10.1073/pnas.0707498104
Homo sapiens Epoxide hydratase IC50 12.0 nM 10.1016/j.bmcl.2013.05.011
Homo sapiens Epoxide hydratase IC50 12.0 nM None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens ES1 IC50 14155.1 nM 10.6019/CHEMBL1201861
Homo sapiens ES3 IC50 18804.14 nM 10.6019/CHEMBL1201861
Homo sapiens ES4 IC50 169989.22 nM 10.6019/CHEMBL1201861
Homo sapiens ES5 IC50 62024.53 nM 10.6019/CHEMBL1201861
Homo sapiens ES6 IC50 22736.58 nM 10.6019/CHEMBL1201861
Homo sapiens ES7 IC50 81850.47 nM 10.6019/CHEMBL1201861
Homo sapiens ES8 IC50 7765.03 nM 10.6019/CHEMBL1201861
Homo sapiens ETK-1 IC50 66255.34 nM 10.6019/CHEMBL1201861
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens EVSA-T Activity 1.009 None 10.1073/pnas.0707498104
Homo sapiens EVSA-T IC50 32258.51 nM 10.6019/CHEMBL1201861
Homo sapiens EW-1 IC50 159688.97 nM 10.6019/CHEMBL1201861
Homo sapiens EW-11 IC50 926942.93 nM 10.6019/CHEMBL1201861
Homo sapiens EW-12 IC50 50042.82 nM 10.6019/CHEMBL1201861
Homo sapiens EW-13 IC50 29174.59 nM 10.6019/CHEMBL1201861
Homo sapiens EW-16 IC50 170978.19 nM 10.6019/CHEMBL1201861
Homo sapiens EW-18 IC50 11904.41 nM 10.6019/CHEMBL1201861
Homo sapiens EW-22 IC50 104956.29 nM 10.6019/CHEMBL1201861
Homo sapiens EW-24 IC50 16166.11 nM 10.6019/CHEMBL1201861
Homo sapiens EW-3 IC50 21188.95 nM 10.6019/CHEMBL1201861
Homo sapiens Exosome RNA helicase MTR4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ferrochelatase, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Fibroblast growth factor receptor 1 IC50 4.63 nM 10.1016/j.bmc.2015.12.038
Homo sapiens Fibroblast growth factor receptor 1 IC50 580.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Fibroblast growth factor receptor 1 IC50 580.0 nM 10.1038/nchembio799
Homo sapiens Fibroblast growth factor receptor 1 IC50 670.0 nM 10.1016/j.ejmech.2018.11.061
Homo sapiens Fibroblast growth factor receptor 1 IC50 670.0 nM 10.1016/j.ejmech.2019.06.063
Homo sapiens Fibroblast growth factor receptor 1 Kd 2500.0 nM 10.1038/nbt1068
Homo sapiens Fibroblast growth factor receptor 1 Kd 2800.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 1 Kd 2800.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 1 Kd 2800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Fibroblast growth factor receptor 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Fibroblast growth factor receptor 1 Ki 2511.89 nM None
Homo sapiens Fibroblast growth factor receptor 2 Kd 2700.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 2 Kd 2700.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 2 Kd 2700.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Fibroblast growth factor receptor 2 Kd nan None 10.1038/nbt1068
Homo sapiens Fibroblast growth factor receptor 3 Inhibition nan % 10.1021/acs.jmedchem.5b01582
Homo sapiens Fibroblast growth factor receptor 3 Kd 4200.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 3 Kd 5900.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 3 Kd 5900.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 3 Kd 5900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Fibroblast growth factor receptor 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Fibroblast growth factor receptor 3 Kd nan None 10.1038/nbt1068
Homo sapiens Fibroblast growth factor receptor 3 Ki 1258.93 nM None
Homo sapiens Fibroblast growth factor receptor 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Focal adhesion kinase 1 Activity 8.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Focal adhesion kinase 1 Inhibition nan % 10.1021/acs.jmedchem.1c00459
Homo sapiens Focal adhesion kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Focal adhesion kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Focal adhesion kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Focal adhesion kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Focal adhesion kinase 1 Kd nan None 10.1038/nbt1068
Homo sapiens Focal adhesion kinase 1 Kd nan None 10.1039/C5MD00462D
Homo sapiens Focal adhesion kinase 1 Ki 6309.57 nM None
Homo sapiens FTC-133 Activity 1.1 None 10.1073/pnas.0707498104
Homo sapiens G-361 Activity 0.097 None 10.1073/pnas.0707498104
Homo sapiens G-361 Activity 0.1 None 10.1073/pnas.0707498104
Homo sapiens G-361 Activity 0.98 None 10.1073/pnas.0707498104
Homo sapiens G-401 Activity 0.659 None 10.1073/pnas.0707498104
Homo sapiens G-402 Activity 0.482 None 10.1073/pnas.0707498104
Homo sapiens GAK IC50 129456.25 nM 10.6019/CHEMBL1201861
Homo sapiens GAMG Activity 0.096 None 10.1073/pnas.0707498104
Homo sapiens GAMG Activity 0.1 None 10.1073/pnas.0707498104
Homo sapiens GAMG Activity 0.74 None 10.1073/pnas.0707498104
Homo sapiens GB-1 IC50 104261.59 nM 10.6019/CHEMBL1201861
Homo sapiens GCIY IC50 165637.89 nM 10.6019/CHEMBL1201861
Homo sapiens GCT Activity 0.802 None 10.1073/pnas.0707498104
Homo sapiens GDM-1 Activity nan None 10.1016/j.bmc.2021.116596
Homo sapiens GDM-1 IC50 906.98 nM 10.6019/CHEMBL1201861
Homo sapiens Geminin Potency 8414.4 nM None
Homo sapiens Geminin Potency 33498.3 nM None
Homo sapiens General transcription and DNA repair factor IIH helicase subunit XPD Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens GES1 GI50 15900.0 nM 10.1021/acs.jmedchem.2c00820
Homo sapiens GES1 GI50 28900.0 nM 10.1021/acs.jmedchem.2c01042
Homo sapiens GES1 IC50 9470.0 nM 10.1016/j.ejmech.2022.114821
Homo sapiens GES1 IC50 9590.0 nM 10.1016/j.ejmech.2021.113192
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens GI-1 IC50 202319.88 nM 10.6019/CHEMBL1201861
Homo sapiens GI-ME-N IC50 184101.82 nM 10.6019/CHEMBL1201861
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glycine--tRNA ligase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Glycogen synthase kinase-3 alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Glycogen synthase kinase-3 alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Glycogen synthase kinase-3 alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Glycogen synthase kinase-3 alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Glycogen synthase kinase-3 alpha Ki 5011.87 nM None
Homo sapiens Glycogen synthase kinase-3 beta Activity 64.0 % 10.1042/bj20070797
Homo sapiens Glycogen synthase kinase-3 beta IC50 8300.0 nM 10.1021/acs.jmedchem.0c01568
Homo sapiens Glycogen synthase kinase-3 beta IC50 32640.0 nM 10.1021/acs.jmedchem.0c01568
Homo sapiens Glycogen synthase kinase-3 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Glycogen synthase kinase-3 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Glycogen synthase kinase-3 beta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Glycogen synthase kinase-3 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Glycogen synthase kinase-3 beta Kd nan None 10.1039/C5MD00462D
Homo sapiens Glycogen synthase kinase-3 beta Ki 3162.28 nM None
Homo sapiens GMS-10 Activity 1.023 None 10.1073/pnas.0707498104
Homo sapiens GOTO IC50 17834.4 nM 10.6019/CHEMBL1201861
Homo sapiens GP5d Activity 1.321 None 10.1073/pnas.0707498104
Homo sapiens G-protein coupled receptor kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens G protein-coupled receptor kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens G protein-coupled receptor kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens G protein-coupled receptor kinase 5 Ki 3981.07 nM None
Homo sapiens G protein-coupled receptor kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens G protein-coupled receptor kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens G protein-coupled receptor kinase 7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens GR-ST IC50 313380.78 nM 10.6019/CHEMBL1201861
Homo sapiens GT3TKB IC50 179825.87 nM 10.6019/CHEMBL1201861
Homo sapiens GTP-binding nuclear protein Ran Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens H4 Activity 0.593 None 10.1073/pnas.0707498104
Homo sapiens HAL-01 IC50 114524.3 nM 10.6019/CHEMBL1201861
Homo sapiens HC-1 IC50 161705.05 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1187 IC50 68581.51 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1395 Activity 0.978 None 10.1073/pnas.0707498104
Homo sapiens HCC1599 IC50 85201.41 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1806 Activity 1.072 None 10.1073/pnas.0707498104
Homo sapiens HCC1937 Activity 1.043 None 10.1073/pnas.0707498104
Homo sapiens HCC1954 Activity 1.08 None 10.1073/pnas.0707498104
Homo sapiens HCC2157 IC50 168840.93 nM 10.6019/CHEMBL1201861
Homo sapiens HCC2218 IC50 3120.03 nM 10.6019/CHEMBL1201861
Homo sapiens HCC 2998 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HCC 2998 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HCC 2998 IC50 888.18 nM 10.6019/CHEMBL1201861
Homo sapiens HCC 2998 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HCC 2998 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HCC 2998 IC50 3160.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens HCC 2998 TGI nan None 10.1016/j.bmc.2022.116894
Homo sapiens HCC 2998 TGI nan None 10.1016/j.ejmech.2017.01.006
Homo sapiens HCC 2998 TGI nan None 10.1016/j.ejmech.2018.07.008
Homo sapiens HCC38 Activity 1.174 None 10.1073/pnas.0707498104
Homo sapiens HCC70 Activity 1.063 None 10.1073/pnas.0707498104
Homo sapiens HCCLM9 Activity 0.74 % 10.1016/j.ejmech.2022.114376
Homo sapiens HCCLM9 Activity 2.14 % 10.1016/j.ejmech.2022.114376
Homo sapiens HCCLM9 Activity 13.52 % 10.1016/j.ejmech.2022.114376
Homo sapiens HCCLM9 Activity 83.59 % 10.1016/j.ejmech.2022.114376
Homo sapiens HCCLM9 Activity nan None 10.1016/j.ejmech.2022.114376
Homo sapiens HCCLM9 IC50 3150.0 nM 10.1021/acs.jmedchem.2c00520
Homo sapiens HCCLM9 IC50 21070.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens HCE-T IC50 108581.93 nM 10.6019/CHEMBL1201861
Homo sapiens HCT-116 Activity 0.461 None 10.1073/pnas.0707498104
Homo sapiens HCT-116 GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HCT-116 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HCT-116 GI50 5400.0 nM 10.1016/j.bmcl.2004.05.048
Homo sapiens HCT-116 GI50 5420.0 nM 10.1016/j.ejmech.2021.113634
Homo sapiens HCT-116 GI50 6600.0 nM 10.1016/j.bmcl.2004.05.048
Homo sapiens HCT-116 GI50 9000.0 nM 10.1021/acs.jmedchem.2c00820
Homo sapiens HCT-116 GI50 19800.0 nM 10.1021/acs.jmedchem.2c01042
Homo sapiens HCT-116 IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HCT-116 IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HCT-116 IC50 2000.0 nM 10.1021/jm300613w
Homo sapiens HCT-116 IC50 2300.0 nM 10.1016/j.bmc.2012.04.006
Homo sapiens HCT-116 IC50 5470.0 nM 10.1016/j.ejmech.2022.114661
Homo sapiens HCT-116 IC50 5650.0 nM 10.1016/j.ejmech.2013.10.049
Homo sapiens HCT-116 IC50 7750.0 nM 10.1007/s00044-012-0400-8
Homo sapiens HCT-116 IC50 7800.0 nM 10.1016/j.bmc.2012.03.018
Homo sapiens HCT-116 IC50 8080.0 nM 10.1016/j.bmc.2013.11.052
Homo sapiens HCT-116 IC50 8080.0 nM 10.1016/j.ejmech.2013.03.043
Homo sapiens HCT-116 IC50 8410.0 nM 10.1016/j.bmc.2018.03.039
Homo sapiens HCT-116 IC50 9400.0 nM 10.1016/j.bmc.2020.115872
Homo sapiens HCT-116 IC50 16120.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens HCT-116 IC50 23310.0 nM 10.1016/j.bmc.2018.03.038
Homo sapiens HCT-116 IC50 168000.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens HCT-116 IC50 nan None 10.1016/j.bmc.2018.05.004
Homo sapiens HCT-116 IC50 nan None 10.1016/j.bmcl.2016.07.068
Homo sapiens HCT-116 Inhibition 11.01 % 10.1016/j.ejmech.2020.112205
Homo sapiens HCT-116 TGI 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HCT-116 TGI 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HCT-116 TGI 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HCT-116 TGI 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HCT-15 GI50 2510.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens HCT-15 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HCT-15 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HCT-15 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HCT-15 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HCT-15 LC50 50100.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens HCT-15 TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HCT-15 TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HCT-15 TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HCT-15 TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HCT-15 TGI 10000.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens HCT-8 Activity 0.756 None 10.1073/pnas.0707498104
Homo sapiens HDLM-2 IC50 16071.43 nM 10.6019/CHEMBL1201861
Homo sapiens HD-MY-Z IC50 8637.46 nM 10.6019/CHEMBL1201861
Homo sapiens HEC-1 Activity 0.29 None 10.1073/pnas.0707498104
Homo sapiens HEC-1 Activity 1.01 None 10.1073/pnas.0707498104
Homo sapiens HEK293 Activity nan None 10.1016/j.bmc.2022.117115
Homo sapiens HEK293 IC50 2950.0 nM 10.1016/j.bmc.2022.116805
Homo sapiens HEK293 IC50 5000.0 nM 10.1016/j.ejmech.2018.11.023
Homo sapiens HEK293 IC50 5000.0 nM 10.1016/j.ejmech.2019.03.012
Homo sapiens HEK293 Inhibition 99.0 % 10.1016/j.bmc.2022.116805
Homo sapiens HEK-293T IC50 6380.0 nM 10.1016/j.ejmech.2022.114821
Homo sapiens HEL IC50 70603.8 nM 10.6019/CHEMBL1201861
Homo sapiens HeLa Activity 0.09 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 0.1 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 0.126 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 0.13 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 0.2 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 0.202 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 0.317 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 0.331 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 0.399 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 1.01 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 1.05 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 1.13 None 10.1073/pnas.0707498104
Homo sapiens HeLa Activity 1.16 None 10.1073/pnas.0707498104
Homo sapiens HeLa FC 35.5 None 10.1016/j.bmc.2019.07.042
Homo sapiens HeLa IC50 270.0 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens HeLa IC50 640.0 nM 10.1016/j.ejmech.2018.07.004
Homo sapiens HeLa IC50 2440.0 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens HeLa IC50 3310.0 nM 10.1016/j.bmcl.2022.128975
Homo sapiens HeLa IC50 4163.0 nM 10.1021/jm301537p
Homo sapiens HeLa IC50 4590.0 nM 10.1039/C8MD00089A
Homo sapiens HeLa IC50 5230.0 nM 10.1016/j.bmcl.2015.08.068
Homo sapiens HeLa IC50 6100.0 nM 10.1016/j.ejmech.2018.11.023
Homo sapiens HeLa IC50 6100.0 nM 10.1016/j.ejmech.2019.03.012
Homo sapiens HeLa IC50 7680.0 nM 10.1039/C3MD00192J
Homo sapiens HeLa IC50 8040.0 nM 10.1016/j.ejmech.2022.114661
Homo sapiens HeLa IC50 8740.0 nM 10.1016/j.ejmech.2018.12.067
Homo sapiens HeLa IC50 12010.0 nM 10.1016/j.bmc.2017.10.027
Homo sapiens Heme oxygenase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Hep 3B2 Activity 1.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 1.5 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 2.0 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 2.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 2.4 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 3.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 4.0 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 5.0 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 5.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 5.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 6.1 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 6.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 6.9 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 7.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 7.29 % 10.1016/j.ejmech.2020.112362
Homo sapiens Hep 3B2 Activity 7.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 7.9 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 8.8 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 9.6 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 10.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 10.8 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 11.8 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 12.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 13.1 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 13.6 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 13.7 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 14.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 15.0 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 15.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 16.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 16.6 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 19.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 19.8 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 21.9 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 22.7 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 23.5 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 24.5 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 27.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 27.8 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 31.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 33.0 % 10.1016/j.ejmech.2020.113081
Homo sapiens Hep 3B2 Activity 34.9 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 35.1 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 35.7 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 35.9 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 38.1 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 39.6 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 40.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 42.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 43.3 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 43.8 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 44.1 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 45.7 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 47.8 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 53.6 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 54.9 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 55.7 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 59.2 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 60.4 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 65.0 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 68.4 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity 84.9 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 Activity nan None 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 GI 8.6 % 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 IC50 2630.0 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens Hep 3B2 IC50 4010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens Hep 3B2 IC50 4330.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens Hep 3B2 IC50 5200.0 nM 10.1016/j.ejmech.2020.112362
Homo sapiens Hep 3B2 IC50 5200.0 nM 10.1021/acs.jnatprod.2c00630
Homo sapiens Hep 3B2 IC50 5490.0 nM 10.1016/j.ejmech.2022.114402
Homo sapiens Hep 3B2 IC50 7700.0 nM 10.1021/acs.jnatprod.2c00908
Homo sapiens Hep 3B2 IC50 8620.0 nM 10.1016/j.ejmech.2020.113081
Homo sapiens Hep 3B2 IC50 9400.0 nM 10.1016/j.ejmech.2017.08.054
Homo sapiens Hep 3B2 IC50 10000.0 nM 10.1016/j.ejmech.2022.114861
Homo sapiens Hep 3B2 IC50 11200.0 nM 10.1016/j.ejmech.2017.03.034
Homo sapiens Hep 3B2 IC50 12400.0 nM 10.1021/acs.jnatprod.2c00888
Homo sapiens Hep 3B2 TGI 71.0 % 10.1021/acs.jmedchem.7b01465
Homo sapiens Hep 3B2 TGI 73.0 % 10.1021/acs.jmedchem.7b01465
Homo sapiens Hepatocyte growth factor receptor IC50 5750.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens Hepatocyte growth factor receptor IC50 nan None 10.1016/j.bmc.2017.09.003
Homo sapiens Hepatocyte growth factor receptor Inhibition nan % 10.1021/acs.jmedchem.5b01582
Homo sapiens Hepatocyte growth factor receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Hepatocyte growth factor receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Hepatocyte growth factor receptor Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Hepatocyte growth factor receptor Ki 2511.89 nM None
Homo sapiens HepG2 Activity 4.1 % 10.1016/j.ejmech.2020.112362
Homo sapiens HepG2 Activity 7.0 % 10.1021/jm501177w
Homo sapiens HepG2 Activity 35.0 % 10.1016/j.ejmech.2020.113081
Homo sapiens HepG2 Activity 75.0 % 10.1021/jm501177w
Homo sapiens HepG2 Activity nan None 10.1016/j.bmc.2017.10.027
Homo sapiens HepG2 Activity nan None 10.1016/j.bmc.2022.117048
Homo sapiens HepG2 EC50 302.0 nM 10.1021/acs.jmedchem.6b00087
Homo sapiens HepG2 GI 59.9 % 10.1016/j.ejmech.2014.11.008
Homo sapiens HepG2 GI50 2500.0 nM 10.1016/j.ejmech.2020.112205
Homo sapiens HepG2 GI50 4500.0 nM 10.1016/j.bmcl.2013.05.011
Homo sapiens HepG2 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens HepG2 IC50 12.4 ug.mL-1 10.1016/j.bmc.2017.10.027
Homo sapiens HepG2 IC50 1060.0 nM 10.1016/j.bmcl.2018.03.089
Homo sapiens HepG2 IC50 2100.0 nM 10.1021/acs.jmedchem.2c00520
Homo sapiens HepG2 IC50 2170.0 nM 10.1016/j.bmc.2021.116384
Homo sapiens HepG2 IC50 2410.0 nM 10.1016/j.ejmech.2019.06.054
Homo sapiens HepG2 IC50 2690.0 nM 10.1016/j.bmc.2022.117115
Homo sapiens HepG2 IC50 2800.0 nM 10.1016/j.ejmech.2018.11.033
Homo sapiens HepG2 IC50 2840.0 nM 10.1016/j.ejmech.2017.02.041
Homo sapiens HepG2 IC50 2860.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HepG2 IC50 3040.0 nM 10.1016/j.bmcl.2019.04.047
Homo sapiens HepG2 IC50 3300.0 nM 10.1016/j.ejmech.2022.114402
Homo sapiens HepG2 IC50 3400.0 nM 10.1016/j.ejmech.2015.05.040
Homo sapiens HepG2 IC50 3440.0 nM 10.1016/j.bmc.2017.09.003
Homo sapiens HepG2 IC50 3500.0 nM 10.1016/j.bmc.2019.07.050
Homo sapiens HepG2 IC50 3500.0 nM 10.1016/j.ejmech.2014.10.064
Homo sapiens HepG2 IC50 3600.0 nM 10.1016/j.bmcl.2019.126711
Homo sapiens HepG2 IC50 3660.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens HepG2 IC50 4000.0 nM 10.1016/j.bmcl.2013.02.034
Homo sapiens HepG2 IC50 5000.0 nM 10.1016/j.bmc.2012.04.006
Homo sapiens HepG2 IC50 5000.0 nM 10.1016/j.bmc.2013.07.026
Homo sapiens HepG2 IC50 5060.0 nM 10.1016/j.bmc.2022.117048
Homo sapiens HepG2 IC50 5060.0 nM 10.1021/acs.jmedchem.0c01512
Homo sapiens HepG2 IC50 5200.0 nM 10.1016/j.ejmech.2019.112016
Homo sapiens HepG2 IC50 5230.0 nM 10.1016/j.ejmech.2018.11.061
Homo sapiens HepG2 IC50 5500.0 nM 10.1021/acs.jnatprod.2c00908
Homo sapiens HepG2 IC50 5500.0 nM 10.1021/acs.jnatprod.9b01282
Homo sapiens HepG2 IC50 5740.0 nM 10.1016/j.ejmech.2014.11.008
Homo sapiens HepG2 IC50 5780.0 nM 10.1016/j.ejmech.2020.112457
Homo sapiens HepG2 IC50 6180.0 nM 10.1016/j.ejmech.2021.113192
Homo sapiens HepG2 IC50 6200.0 nM 10.1016/j.ejmech.2017.08.054
Homo sapiens HepG2 IC50 6300.0 nM 10.1016/j.bmc.2013.07.026
Homo sapiens HepG2 IC50 6400.0 nM 10.1021/acs.jmedchem.0c02026
Homo sapiens HepG2 IC50 6500.0 nM 10.1016/j.bmcl.2021.127788
Homo sapiens HepG2 IC50 6540.0 nM 10.1016/j.bmcl.2022.128975
Homo sapiens HepG2 IC50 6700.0 nM 10.1016/j.bmcl.2015.06.076
Homo sapiens HepG2 IC50 6700.0 nM 10.1016/j.ejmech.2020.113102
Homo sapiens HepG2 IC50 7220.0 nM 10.1016/j.ejmech.2020.113081
Homo sapiens HepG2 IC50 7310.0 nM 10.1016/j.bmc.2020.115872
Homo sapiens HepG2 IC50 7670.0 nM 10.1016/j.ejmech.2020.112581
Homo sapiens HepG2 IC50 7839.0 nM 10.1016/j.bmc.2019.06.001
Homo sapiens HepG2 IC50 8000.0 nM 10.1021/acs.jnatprod.0c00396
Homo sapiens HepG2 IC50 8270.0 nM 10.1016/j.ejmech.2018.09.005
Homo sapiens HepG2 IC50 8420.0 nM 10.1016/j.ejmech.2013.06.055
Homo sapiens HepG2 IC50 8670.0 nM 10.1016/j.ejmech.2014.03.020
Homo sapiens HepG2 IC50 9140.0 nM 10.1016/j.ejmech.2015.10.045
Homo sapiens HepG2 IC50 9180.0 nM 10.1016/j.ejmech.2022.114661
Homo sapiens HepG2 IC50 9700.0 nM 10.1021/acs.jnatprod.2c00630
Homo sapiens HepG2 IC50 9750.0 nM 10.1016/j.ejmech.2020.112362
Homo sapiens HepG2 IC50 10000.0 nM 10.1016/j.ejmech.2022.114861
Homo sapiens HepG2 IC50 10480.0 nM 10.1039/C4MD00536H
Homo sapiens HepG2 IC50 11490.0 nM 10.1021/jm1014814
Homo sapiens HepG2 IC50 12000.0 nM 10.1016/j.bmcl.2016.07.007
Homo sapiens HepG2 IC50 12540.0 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens HepG2 IC50 12669.0 nM 10.1039/C2MD20275A
Homo sapiens HepG2 IC50 15000.0 nM 10.1016/j.bmc.2017.10.027
Homo sapiens HepG2 IC50 16300.0 nM 10.1016/j.ejmech.2018.08.017
Homo sapiens HepG2 IC50 16600.0 nM 10.1021/acs.jnatprod.2c00888
Homo sapiens HepG2 IC50 29000.0 nM 10.1039/C8MD00057C
Homo sapiens HepG2 IC50 29350.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens HepG2 IC50 29600.0 nM 10.1016/j.ejmech.2020.112942
Homo sapiens HepG2 IC50 9640000.0 nM 10.1016/j.bmc.2020.115599
Homo sapiens HepG2 Inhibition 100.0 % 10.1016/j.bmc.2019.06.001
Homo sapiens HepG2 Potency 15848.9 nM None
Homo sapiens HepG2 TGI 56.0 % 10.1021/acs.jmedchem.7b01465
Homo sapiens HepG2 TGI 72.0 % 10.1021/acs.jmedchem.7b01465
Homo sapiens HepG2 TGI 88.4 % 10.1016/j.bmc.2022.116757
Homo sapiens HepG2 TGI nan None 10.1016/j.ejmech.2013.06.055
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HGC-27 Activity 0.809 None 10.1073/pnas.0707498104
Homo sapiens HGC-27 Activity 6.91 % 10.1016/j.ejmech.2021.113192
Homo sapiens HGC-27 Activity 18.5 % 10.1016/j.ejmech.2021.113192
Homo sapiens HGC-27 Activity 24.0 % 10.1016/j.ejmech.2021.113192
Homo sapiens HGC-27 Activity 25.41 % 10.1016/j.ejmech.2021.113192
Homo sapiens HGC-27 Activity 50.6 % 10.1016/j.ejmech.2021.113192
Homo sapiens HGC-27 IC50 5150.0 nM 10.1016/j.ejmech.2022.114821
Homo sapiens HGC-27 IC50 5220.0 nM 10.1016/j.ejmech.2021.113192
Homo sapiens HGC-27 IC50 150000.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens HH IC50 11387.58 nM 10.6019/CHEMBL1201861
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone deacetylase 1 IC50 nan None 10.1016/j.bmcl.2019.04.047
Homo sapiens Histone deacetylase 6 Activity 2.1 % 10.1021/acs.jmedchem.7b01465
Homo sapiens Histone deacetylase 6 Activity 8.0 % 10.1021/acs.jmedchem.7b01465
Homo sapiens Histone deacetylase 6 Inhibition 7.48 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition 27.49 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition nan % 10.1016/j.bmcl.2019.04.047
Homo sapiens Histone deacetylase 8 Inhibition nan % 10.1016/j.bmcl.2019.04.047
Homo sapiens HK-2 IC50 2600.0 nM 10.1021/acs.jmedchem.9b00598
Homo sapiens HL-60 Activity 73.2 % 10.1016/j.bmcl.2022.128799
Homo sapiens HL-60 Activity nan None 10.1039/C8MD00089A
Homo sapiens HL-60 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HL-60 IC50 500.0 nM 10.1021/acs.jmedchem.1c02079
Homo sapiens HL-60 IC50 1680.0 nM 10.1016/j.ejmech.2014.05.025
Homo sapiens HL-60 IC50 2590.0 nM 10.1039/C8MD00089A
Homo sapiens HL-60 IC50 2810.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens HL-60 IC50 3062.99 nM 10.6019/CHEMBL1201861
Homo sapiens HL-60 IC50 3140.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens HL-60 IC50 5000.0 nM 10.1016/j.ejmech.2018.11.023
Homo sapiens HL-60 TGI 100000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HL-60(TB) GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HL-60(TB) IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HL-60(TB) IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HL-60(TB) IC50 1580.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens HL-60(TB) TGI 100000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HL-60(TB) TGI 100000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HL-60(TB) TGI 100000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HLE Activity 0.457 None 10.1073/pnas.0707498104
Homo sapiens HMEC-1 Activity 46.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens HMEC-1 Activity 64.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens HMEC-1 IC50 34000.0 nM 10.1016/j.ejmech.2018.11.023
Homo sapiens HMEC-1 IC50 34000.0 nM 10.1016/j.ejmech.2019.03.012
Homo sapiens HMEC-1 MAC 10.0 uM 10.1016/j.ejmech.2018.11.023
Homo sapiens HMEC-1 MAC 10.0 uM 10.1016/j.ejmech.2019.03.012
Homo sapiens Homeodomain-interacting protein kinase 1 IC50 100.0 nM 10.1016/j.ejmech.2021.113299
Homo sapiens Homeodomain-interacting protein kinase 1 Kd 1100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Homeodomain-interacting protein kinase 1 Kd 3300.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 2 Activity 15.0 % 10.1042/bj20070797
Homo sapiens Homeodomain-interacting protein kinase 2 IC50 100.0 nM 10.1016/j.ejmech.2021.113299
Homo sapiens Homeodomain-interacting protein kinase 2 Kd 1700.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 2 Kd 1700.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Homeodomain-interacting protein kinase 2 Ki 501.19 nM None
Homo sapiens Homeodomain-interacting protein kinase 3 Activity 21.0 % 10.1042/bj20070797
Homo sapiens Homeodomain-interacting protein kinase 3 IC50 100.0 nM 10.1016/j.ejmech.2021.113299
Homo sapiens Homeodomain-interacting protein kinase 3 Kd 390.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Homeodomain-interacting protein kinase 3 Kd 440.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 4 IC50 3.0 nM None
Homo sapiens Homeodomain-interacting protein kinase 4 IC50 100.0 nM 10.1016/j.ejmech.2021.113299
Homo sapiens Homeodomain-interacting protein kinase 4 Kd 2.7 nM 10.1182/blood-2009-05-222034
Homo sapiens Homeodomain-interacting protein kinase 4 Kd 3.3 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 4 Ki 10.0 nM None
Homo sapiens Homo sapiens Activity 5.0 % 10.1016/j.bmcl.2015.03.088
Homo sapiens Homo sapiens Activity 34.0 % 10.1016/j.bmcl.2015.03.088
Homo sapiens Homo sapiens Activity nan None 10.1002/hep.27206
Homo sapiens Homo sapiens Cmax 132.0 nM 10.1002/hep.27206
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 8.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens Survival 3.4 months 10.1016/j.ejmech.2017.08.007
Homo sapiens Homo sapiens Survival 5.5 months 10.1016/j.ejmech.2017.08.007
Homo sapiens Homo sapiens Survival 6.5 months 10.1016/j.ejmech.2017.08.007
Homo sapiens Homo sapiens Survival 17.8 months 10.1016/j.ejmech.2017.08.007
Homo sapiens HOP-62 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HOP-62 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HOP-62 IC50 850.88 nM 10.6019/CHEMBL1201861
Homo sapiens HOP-62 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HOP-62 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HOP-62 TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HOP-62 TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HOP-62 TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HOP-62 TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HOP-92 Activity 0.913 None 10.1073/pnas.0707498104
Homo sapiens HOP-92 GI50 1580.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens HOP-92 GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HOP-92 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HOP-92 IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HOP-92 IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HOP-92 LC50 63100.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens HOP-92 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HOP-92 TGI 5010.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens HOP-92 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HOP-92 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HOP-92 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens Hormonally up-regulated neu tumor-associated kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Hormonally up-regulated neu tumor-associated kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens HOS Activity 0.602 None 10.1073/pnas.0707498104
Homo sapiens HOS-TE85 TGI 44.2 % 10.1016/j.ejmech.2021.114010
Homo sapiens HPAC Activity 0.962 None 10.1073/pnas.0707498104
Homo sapiens HPAF-II Activity 1.217 None 10.1073/pnas.0707498104
Homo sapiens HS27 GI50 7850.0 nM 10.1016/j.bmc.2011.01.067
Homo sapiens HS27 GI50 30000.0 nM 10.1016/j.ejmech.2015.08.031
Homo sapiens HS27 IC50 7800.0 nM 10.1016/j.bmcl.2009.08.005
Homo sapiens HS27 IC50 7800.0 nM 10.1016/j.bmcl.2009.10.051
Homo sapiens HS27 IC50 7800.0 nM 10.1016/j.ejmech.2019.112029
Homo sapiens HS27 IC50 7850.0 nM 10.1016/j.bmcl.2009.05.007
Homo sapiens Hs-578T GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens Hs-578T GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens Hs-578T IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens Hs-578T IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens Hs-578T TGI 3980.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens Hs-578T TGI 3980.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens Hs-578T TGI 3980.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens Hs-578T TGI 3980.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens Hs 683 Activity 0.609 None 10.1073/pnas.0707498104
Homo sapiens HT IC50 96743.58 nM 10.6019/CHEMBL1201861
Homo sapiens HT-1080 Activity 0.04 None 10.1073/pnas.0707498104
Homo sapiens HT-1080 Activity 0.67 None 10.1073/pnas.0707498104
Homo sapiens HT-1080 IC50 10000.0 nM 10.1016/j.ejmech.2022.114861
Homo sapiens HT-144 IC50 17005.95 nM 10.6019/CHEMBL1201861
Homo sapiens HT-29 Activity 1.197 None 10.1073/pnas.0707498104
Homo sapiens HT-29 Activity 1.69 % 10.1016/j.ejmech.2020.112461
Homo sapiens HT-29 Activity 4.23 % 10.1016/j.ejmech.2020.112461
Homo sapiens HT-29 Activity 5.76 % 10.1016/j.ejmech.2020.112461
Homo sapiens HT-29 Activity 8.72 % 10.1016/j.ejmech.2020.112461
Homo sapiens HT-29 Activity 12.19 % 10.1016/j.ejmech.2020.112461
Homo sapiens HT-29 Activity 14.54 % 10.1016/j.ejmech.2020.112461
Homo sapiens HT-29 Activity 75.23 % 10.1016/j.ejmech.2020.112461
Homo sapiens HT-29 Activity 81.3 % 10.1016/j.ejmech.2020.112461
Homo sapiens HT-29 EC50 1000.0 nM 10.1021/acs.jmedchem.6b00087
Homo sapiens HT-29 GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens HT-29 GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens HT-29 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HT-29 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HT-29 GI50 25400.0 nM 10.1021/acs.jmedchem.2c00820
Homo sapiens HT-29 GI50 25600.0 nM 10.1021/acs.jmedchem.2c01042
Homo sapiens HT-29 IC50 390.0 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens HT-29 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HT-29 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HT-29 IC50 2500.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens HT-29 IC50 2580.0 nM 10.1016/j.ejmech.2018.05.054
Homo sapiens HT-29 IC50 3270.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens HT-29 IC50 3370.0 nM 10.1016/j.ejmech.2016.02.071
Homo sapiens HT-29 IC50 3610.0 nM 10.1016/j.ejmech.2014.04.059
Homo sapiens HT-29 IC50 3610.0 nM 10.1016/j.ejmech.2014.07.099
Homo sapiens HT-29 IC50 3610.0 nM 10.1016/j.ejmech.2014.10.022
Homo sapiens HT-29 IC50 3610.0 nM 10.1016/j.ejmech.2018.09.005
Homo sapiens HT-29 IC50 3970.0 nM 10.1016/j.ejmech.2018.03.001
Homo sapiens HT-29 IC50 4000.0 nM 10.1016/j.bmcl.2013.02.034
Homo sapiens HT-29 IC50 5290.0 nM 10.1016/j.ejmech.2019.111700
Homo sapiens HT-29 IC50 5570.0 nM 10.1016/j.ejmech.2021.113192
Homo sapiens HT-29 IC50 5900.0 nM 10.1016/j.ejmech.2017.08.054
Homo sapiens HT-29 IC50 6600.0 nM 10.1016/j.ejmech.2018.11.033
Homo sapiens HT-29 IC50 8440.0 nM 10.1016/j.bmc.2018.03.038
Homo sapiens HT-29 IC50 10000.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens HT-29 IC50 11510.0 nM 10.1021/acs.jmedchem.2c01518
Homo sapiens HT-29 IC50 15200.0 nM 10.1016/j.ejmech.2014.03.020
Homo sapiens HT-29 IC50 17000.0 nM 10.1016/j.ejmech.2018.11.023
Homo sapiens HT-29 IC50 17000.0 nM 10.1016/j.ejmech.2019.03.012
Homo sapiens HT-29 IC50 17280.0 nM 10.1016/j.ejmech.2020.112461
Homo sapiens HT-29 IC50 150000.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens HT-29 IC50 10050000.0 nM 10.1016/j.bmc.2020.115599
Homo sapiens HT-29 IC50 nan None 10.1016/j.ejmech.2015.12.032
Homo sapiens HT-29 LC50 39800.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens HT-29 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens HT-29 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens HT-29 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens HT-29 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens HT-29 TGI 7940.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens HT-3 Activity 0.843 None 10.1073/pnas.0707498104
Homo sapiens HTC-C3 Activity 0.701 None 10.1073/pnas.0707498104
Homo sapiens Huh-7 Activity 0.23 % 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 Activity 0.32 % 10.1016/j.ejmech.2022.114376
Homo sapiens Huh-7 Activity 1.18 % 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 Activity 3.72 % 10.1016/j.ejmech.2022.114376
Homo sapiens Huh-7 Activity 3.94 % 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 Activity 9.16 % 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 Activity 11.18 % 10.1016/j.ejmech.2022.114376
Homo sapiens Huh-7 Activity 21.0 % 10.1016/j.ejmech.2020.113081
Homo sapiens Huh-7 Activity 36.16 % 10.1016/j.ejmech.2021.113489
Homo sapiens Huh-7 Activity 37.84 % 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 Activity 53.0 % 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 Activity 84.77 % 10.1016/j.ejmech.2022.114376
Homo sapiens Huh-7 Activity 94.6 % 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 Activity nan None 10.1016/j.ejmech.2022.114376
Homo sapiens Huh-7 Activity nan None 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 GI50 4000.0 nM 10.1016/j.bmcl.2013.05.011
Homo sapiens Huh-7 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens Huh-7 IC50 2600.0 nM 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 IC50 2680.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens Huh-7 IC50 4250.0 nM 10.1021/acs.jmedchem.0c02026
Homo sapiens Huh-7 IC50 7100.0 nM 10.1016/j.ejmech.2020.113102
Homo sapiens Huh-7 IC50 7550.0 nM 10.1016/j.ejmech.2020.113081
Homo sapiens Huh-7 IC50 7920.0 nM 10.1016/j.ejmech.2020.112581
Homo sapiens Huh-7 IC50 9700.0 nM 10.1021/acs.jnatprod.2c00888
Homo sapiens Huh-7 IC50 10000.0 nM 10.1016/j.ejmech.2022.114861
Homo sapiens Huh-7 IC50 10100.0 nM 10.1021/acs.jnatprod.0c00396
Homo sapiens Huh-7 IC50 10940.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens Huh-7 IC50 11300.0 nM 10.1016/j.bmcl.2016.07.007
Homo sapiens Huh-7 IC50 nan None 10.1016/j.bmcl.2016.07.068
Homo sapiens Huh-7 Inhibition nan % 10.1016/j.ejmech.2021.113489
Homo sapiens Huh-7 TGI 46.27 % 10.1021/acs.jmedchem.2c00520
Homo sapiens Huh-7 TGI 61.0 % 10.1021/acs.jmedchem.7b01465
Homo sapiens Huh-7.5 CC50 20000.0 nM 10.1021/acs.jmedchem.0c01467
Homo sapiens HuP-T3 Activity 1.021 None 10.1073/pnas.0707498104
Homo sapiens HuP-T4 Activity 0.832 None 10.1073/pnas.0707498104
Homo sapiens HuTu80 IC50 21394.65 nM 10.6019/CHEMBL1201861
Homo sapiens HUVEC Activity 2.09 % 10.1016/j.ejmech.2020.112942
Homo sapiens HUVEC Activity 16.4 % 10.1016/j.ejmech.2020.112942
Homo sapiens HUVEC Activity 18.0 % 10.1016/j.bmc.2015.08.010
Homo sapiens HUVEC Activity 23.8 % 10.1016/j.ejmech.2020.112942
Homo sapiens HUVEC Activity 27.1 % 10.1016/j.ejmech.2020.112942
Homo sapiens HUVEC Activity 58.69 % 10.1016/j.ejmech.2020.112942
Homo sapiens HUVEC Activity 59.9 % 10.1016/j.ejmech.2020.112942
Homo sapiens HUVEC Activity 100.0 % 10.1016/j.bmc.2018.03.039
Homo sapiens HUVEC Activity nan None 10.1016/j.bmc.2015.08.010
Homo sapiens HUVEC Activity nan None 10.1016/j.bmc.2018.03.039
Homo sapiens HUVEC EC50 718.0 nM 10.1021/acs.jmedchem.6b00087
Homo sapiens HUVEC GI 37.4 % 10.1016/j.ejmech.2017.03.034
Homo sapiens HUVEC GI 41.4 % 10.1016/j.ejmech.2017.03.034
Homo sapiens HUVEC GI 60.0 % 10.1016/j.ejmech.2017.03.034
Homo sapiens HUVEC GI 84.66 % 10.1021/acs.jmedchem.7b01091
Homo sapiens HUVEC GI50 6000.0 nM 10.1016/j.bmcl.2013.05.011
Homo sapiens HUVEC IC50 0.59 nM 10.1038/nchembio.117
Homo sapiens HUVEC IC50 1490.0 nM 10.1021/acs.jmedchem.7b01091
Homo sapiens HUVEC IC50 2690.0 nM 10.1016/j.ejmech.2018.05.054
Homo sapiens HUVEC IC50 2800.0 nM 10.1016/j.ejmech.2020.112942
Homo sapiens HUVEC IC50 4000.0 nM 10.1016/j.bmcl.2013.03.042
Homo sapiens HUVEC IC50 4100.0 nM 10.1016/j.bmcl.2019.126711
Homo sapiens HUVEC IC50 5350.0 nM 10.1016/j.ejmech.2019.06.054
Homo sapiens HUVEC IC50 6420.0 nM 10.1016/j.bmc.2013.11.052
Homo sapiens HUVEC IC50 6420.0 nM 10.1016/j.ejmech.2013.03.043
Homo sapiens HUVEC IC50 8330.0 nM 10.1016/j.ejmech.2021.113192
Homo sapiens HUVEC IC50 9660.0 nM 10.1016/j.ejmech.2022.114821
Homo sapiens HUVEC IC50 40600.0 nM 10.1016/j.ejmech.2017.03.034
Homo sapiens HUVEC Inhibition nan % 10.1016/j.bmc.2015.08.010
Homo sapiens HUVEC Inhibition nan % 10.1016/j.ejmech.2015.02.019
Homo sapiens HUVEC Inhibition nan % 10.1016/j.ejmech.2020.112457
Homo sapiens HUVEC Inhibition nan % 10.1016/j.ejmech.2021.113192
Homo sapiens HUVEC Inhibition nan % 10.1039/C4MD00536H
Homo sapiens IGR-1 Activity 0.755 None 10.1073/pnas.0707498104
Homo sapiens IGROV-1 Activity 1.089 None 10.1073/pnas.0707498104
Homo sapiens IGROV-1 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens IGROV-1 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens IGROV-1 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens IGROV-1 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens IGROV-1 TGI 10000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens IGROV-1 TGI 10000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens IGROV-1 TGI 10000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens IGROV-1 TGI 10000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens IM-9 IC50 916558.6 nM 10.6019/CHEMBL1201861
Homo sapiens IMR-5 IC50 505117.46 nM 10.6019/CHEMBL1201861
Homo sapiens Inhibitor of nuclear factor kappa B kinase alpha subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase alpha subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Inhibitor of nuclear factor kappa B kinase alpha subunit Ki 3981.07 nM None
Homo sapiens Inhibitor of nuclear factor kappa B kinase beta subunit Activity 94.0 % 10.1042/bj20070797
Homo sapiens Inhibitor of nuclear factor kappa B kinase beta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase beta subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Inhibitor of nuclear factor kappa B kinase beta subunit Ki 3162.28 nM None
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Ki 3162.28 nM None
Homo sapiens Inosine-5'-monophosphate dehydrogenase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Insulin-like growth factor I receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Insulin-like growth factor I receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Insulin-like growth factor I receptor Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Insulin-like growth factor I receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Insulin-like growth factor I receptor Ki 1995.26 nM None
Homo sapiens Insulin receptor IC50 5300.0 nM 10.1038/nchembio.117
Homo sapiens Insulin receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Insulin receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Insulin receptor Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Insulin receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Insulin receptor Kd nan None 10.1038/nbt1068
Homo sapiens Insulin receptor Ki 5011.87 nM None
Homo sapiens Insulin receptor-related protein Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Insulin receptor-related protein Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Insulin receptor-related protein Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Interferon-induced, double-stranded RNA-activated protein kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Interferon-induced, double-stranded RNA-activated protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Interferon-induced, double-stranded RNA-activated protein kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Interleukin-1 receptor-associated kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Interleukin-1 receptor-associated kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Interleukin-1 receptor-associated kinase 1 Ki 7943.28 nM None
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Interleukin-1 receptor-associated kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Interleukin-1 receptor-associated kinase 4 Ki 10000.0 nM None
Homo sapiens IPC-298 Activity 0.751 None 10.1073/pnas.0707498104
Homo sapiens Ishikawa Activity 0.098 None 10.1073/pnas.0707498104
Homo sapiens Ishikawa Activity 0.1 None 10.1073/pnas.0707498104
Homo sapiens Ishikawa Activity 0.216 None 10.1073/pnas.0707498104
Homo sapiens Ishikawa Activity 0.22 None 10.1073/pnas.0707498104
Homo sapiens Ishikawa Activity 1.12 None 10.1073/pnas.0707498104
Homo sapiens Ishikawa Activity 1.17 None 10.1073/pnas.0707498104
Homo sapiens Isoleucine--tRNA ligase, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens IST-MEL1 IC50 8400.02 nM 10.6019/CHEMBL1201861
Homo sapiens IST-MES1 IC50 40309.57 nM 10.6019/CHEMBL1201861
Homo sapiens IST-SL1 IC50 14961.57 nM 10.6019/CHEMBL1201861
Homo sapiens IST-SL2 IC50 24436.16 nM 10.6019/CHEMBL1201861
Homo sapiens J82 Activity 0.664 None 10.1073/pnas.0707498104
Homo sapiens JAR IC50 5508.24 nM 10.6019/CHEMBL1201861
Homo sapiens JIYOYE IC50 10474.47 nM 10.6019/CHEMBL1201861
Homo sapiens J-RT3-T3-5 IC50 951053.2 nM 10.6019/CHEMBL1201861
Homo sapiens Jurkat IC50 14370.0 nM 10.1021/acs.jmedchem.2c01518
Homo sapiens JVM-2 IC50 211055.89 nM 10.6019/CHEMBL1201861
Homo sapiens JVM-3 IC50 369990.75 nM 10.6019/CHEMBL1201861
Homo sapiens K052 IC50 2746.16 nM 10.6019/CHEMBL1201861
Homo sapiens K5 IC50 38429.98 nM 10.6019/CHEMBL1201861
Homo sapiens K562 GI50 612.0 nM 10.1016/j.ejmech.2020.112205
Homo sapiens K562 GI50 3160.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens K562 GI50 3160.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens K562 GI50 3160.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens K562 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens K562 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens K562 GI50 6200.0 nM 10.1016/j.bmc.2011.06.016
Homo sapiens K562 GI50 7300.0 nM 10.1016/j.bmc.2013.03.083
Homo sapiens K562 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens K562 IC50 860.0 nM 10.1016/j.bmc.2013.11.027
Homo sapiens K562 IC50 860.0 nM 10.1039/C3MD00192J
Homo sapiens K562 IC50 1220.0 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens K562 IC50 2810.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens K562 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens K562 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens K562 IC50 5080.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens K562 IC50 13850.0 nM 10.1016/j.ejmech.2013.03.043
Homo sapiens K562 IC50 17230.0 nM 10.1016/j.bmcl.2019.04.047
Homo sapiens K562 IC50 18714.3 nM 10.6019/CHEMBL1201861
Homo sapiens K562 IC50 nan None 10.1016/j.bmc.2013.07.026
Homo sapiens K562 LC50 100000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens K562 LC50 100000.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens K562 TGI 100000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens K562 TGI 100000.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens K562 TGI nan None 10.1016/j.bmc.2022.116894
Homo sapiens K562 TGI nan None 10.1016/j.ejmech.2017.01.006
Homo sapiens K562 TGI nan None 10.1016/j.ejmech.2018.07.008
Homo sapiens KALS-1 IC50 197799.52 nM 10.6019/CHEMBL1201861
Homo sapiens Kappa opioid receptor AC50 23000.1 nM 10.1038/s41467-023-40064-9
Homo sapiens KARPAS-299 IC50 94812.48 nM 10.6019/CHEMBL1201861
Homo sapiens KARPAS-422 IC50 256437.76 nM 10.6019/CHEMBL1201861
Homo sapiens KARPAS-45 IC50 159509.58 nM 10.6019/CHEMBL1201861
Homo sapiens Kasumi 1 IC50 15.0 nM 10.1016/j.bmc.2010.05.021
Homo sapiens Kasumi 1 IC50 471324.12 nM 10.6019/CHEMBL1201861
Homo sapiens KB GI50 5430.0 nM 10.1016/j.ejmech.2021.113634
Homo sapiens KE-37 IC50 192590.08 nM 10.6019/CHEMBL1201861
Homo sapiens KETR3 IC50 8270.0 nM 10.1016/j.ejmech.2018.09.005
Homo sapiens KETR3 IC50 18800.0 nM 10.1016/j.ejmech.2014.03.020
Homo sapiens KG-1 IC50 1479.35 nM 10.6019/CHEMBL1201861
Homo sapiens KGN IC50 212554.62 nM 10.6019/CHEMBL1201861
Homo sapiens KINGS-1 IC50 142063.91 nM 10.6019/CHEMBL1201861
Homo sapiens KM12 GI50 1580.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens KM12 GI50 1580.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens KM12 GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens KM12 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens KM12 IC50 1020.98 nM 10.6019/CHEMBL1201861
Homo sapiens KM12 IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens KM12 IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens KM12 LC50 31600.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens KM12 TGI 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens KM12 TGI 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens KM12 TGI 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens KM12 TGI 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens KM12 TGI 7940.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens KM-H2 Activity 0.986 None 10.1073/pnas.0707498104
Homo sapiens KM-H2 IC50 20318.42 nM 10.6019/CHEMBL1201861
Homo sapiens KMOE-2 IC50 2813.5 nM 10.6019/CHEMBL1201861
Homo sapiens KMS-12-PE IC50 76261.56 nM 10.6019/CHEMBL1201861
Homo sapiens KNS-42 IC50 37123.72 nM 10.6019/CHEMBL1201861
Homo sapiens KNS-81-FD IC50 45405.81 nM 10.6019/CHEMBL1201861
Homo sapiens KP-4 Activity 0.872 None 10.1073/pnas.0707498104
Homo sapiens KP-N-YN IC50 889049.58 nM 10.6019/CHEMBL1201861
Homo sapiens KP-N-YS IC50 164699.73 nM 10.6019/CHEMBL1201861
Homo sapiens KS-1 IC50 3881.98 nM 10.6019/CHEMBL1201861
Homo sapiens KU-19-19 Activity 0.469 None 10.1073/pnas.0707498104
Homo sapiens KU812 cell line IC50 298612.87 nM 10.6019/CHEMBL1201861
Homo sapiens KURAMOCHI IC50 84948.48 nM 10.6019/CHEMBL1201861
Homo sapiens KY821 IC50 675008.98 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-140 Activity 0.837 None 10.1073/pnas.0707498104
Homo sapiens KYSE-180 Activity 0.772 None 10.1073/pnas.0707498104
Homo sapiens KYSE-270 Activity 0.759 None 10.1073/pnas.0707498104
Homo sapiens KYSE-410 Activity 0.899 None 10.1073/pnas.0707498104
Homo sapiens KYSE-450 Activity 1.212 None 10.1073/pnas.0707498104
Homo sapiens KYSE-510 Activity 0.67 None 10.1073/pnas.0707498104
Homo sapiens L02 IC50 5980.0 nM 10.1021/acs.jmedchem.2c00520
Homo sapiens L02 IC50 9100.0 nM 10.1021/acs.jnatprod.9b01282
Homo sapiens L02 IC50 52870.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens L02 IC50 72900.0 nM 10.1016/j.bmcl.2019.126711
Homo sapiens L02 IC50 nan None 10.1039/d2md00065b
Homo sapiens L-363 IC50 499225.55 nM 10.6019/CHEMBL1201861
Homo sapiens L-428 IC50 203140.94 nM 10.6019/CHEMBL1201861
Homo sapiens L-540 IC50 2757.89 nM 10.6019/CHEMBL1201861
Homo sapiens LAMA-84 IC50 1376.48 nM 10.6019/CHEMBL1201861
Homo sapiens LAN-6 IC50 68165.39 nM 10.6019/CHEMBL1201861
Homo sapiens LB1047-RCC IC50 79147.72 nM 10.6019/CHEMBL1201861
Homo sapiens LB2241-RCC IC50 33313.51 nM 10.6019/CHEMBL1201861
Homo sapiens LB2518-MEL IC50 1208.09 nM 10.6019/CHEMBL1201861
Homo sapiens LB373-MEL-D IC50 21561.54 nM 10.6019/CHEMBL1201861
Homo sapiens LB647-SCLC IC50 161784.47 nM 10.6019/CHEMBL1201861
Homo sapiens LB771-HNC IC50 270973.76 nM 10.6019/CHEMBL1201861
Homo sapiens LB831-BLC IC50 36065.37 nM 10.6019/CHEMBL1201861
Homo sapiens LB996-RCC IC50 70696.07 nM 10.6019/CHEMBL1201861
Homo sapiens LC-1F IC50 9108.34 nM 10.6019/CHEMBL1201861
Homo sapiens LC-2-ad GI50 3224.13 nM 10.1021/acs.jmedchem.1c01280
Homo sapiens LC-2-ad IC50 27623.12 nM 10.6019/CHEMBL1201861
Homo sapiens LC4-1 IC50 16611.93 nM 10.6019/CHEMBL1201861
Homo sapiens LCLC-97TM1 Activity 0.988 None 10.1073/pnas.0707498104
Homo sapiens Leucine-rich repeat serine/threonine-protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Leucine-rich repeat serine/threonine-protein kinase 2 Ki 2511.89 nM None
Homo sapiens Leukocyte tyrosine kinase receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Leukocyte tyrosine kinase receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Leukocyte tyrosine kinase receptor Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Leukocyte tyrosine kinase receptor Ki 2511.89 nM None
Homo sapiens LIM domain kinase 1 Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens LIM domain kinase 1 Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens LIM domain kinase 1 Kd 1600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens LIM domain kinase 1 Kd 2200.0 nM 10.1038/nbt1068
Homo sapiens LIM domain kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens LIM domain kinase 1 Ki 630.96 nM None
Homo sapiens LIM domain kinase 2 Kd 9600.0 nM 10.1038/nbt.1990
Homo sapiens LIM domain kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens LIM domain kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens LIM domain kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Liver T1/2 5.6 hr 10.1016/j.ejmech.2017.02.041
Homo sapiens Liver glycogen phosphorylase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Liver microsomes Stability 80.0 % 10.1016/j.bmcl.2008.04.002
Homo sapiens LK-2 Activity 0.532 None 10.1073/pnas.0707498104
Homo sapiens LN-405 Activity 0.84 None 10.1073/pnas.0707498104
Homo sapiens LNCaP-Clone-FGC IC50 279120.06 nM 10.6019/CHEMBL1201861
Homo sapiens Long-chain-fatty-acid--CoA ligase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens LOUCY IC50 477768.35 nM 10.6019/CHEMBL1201861
Homo sapiens LoVo Activity 0.15 None 10.1073/pnas.0707498104
Homo sapiens LoVo Activity 0.88 None 10.1073/pnas.0707498104
Homo sapiens LoVo IC50 250.0 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens LoVo IC50 2520.0 nM 10.1016/j.ejmech.2018.12.067
Homo sapiens LoVo IC50 3300.0 nM 10.1016/j.bmcl.2013.02.034
Homo sapiens LoVo IC50 6560.0 nM 10.1016/j.bmc.2013.11.027
Homo sapiens LoVo IC50 6560.0 nM 10.1039/C3MD00192J
Homo sapiens LoVo IC50 9470.0 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens LoVo IC50 14570.0 nM 10.1021/acs.jmedchem.0c01512
Homo sapiens LOX IMVI GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens LOX IMVI GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens LOX IMVI IC50 263135.73 nM 10.6019/CHEMBL1201861
Homo sapiens LOX IMVI TGI 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens LOX IMVI TGI 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens LP-1 IC50 33995.6 nM 10.6019/CHEMBL1201861
Homo sapiens LS-1034 IC50 188889.46 nM 10.6019/CHEMBL1201861
Homo sapiens LS-123 IC50 107498.94 nM 10.6019/CHEMBL1201861
Homo sapiens LS174T Activity 1.089 None 10.1073/pnas.0707498104
Homo sapiens LS-411N IC50 86701.31 nM 10.6019/CHEMBL1201861
Homo sapiens LS-513 IC50 33863.78 nM 10.6019/CHEMBL1201861
Homo sapiens LU-134-A IC50 275414.44 nM 10.6019/CHEMBL1201861
Homo sapiens LU-135 Activity 0.568 None 10.1073/pnas.0707498104
Homo sapiens LU-139 IC50 12541.27 nM 10.6019/CHEMBL1201861
Homo sapiens LU-165 IC50 19700.83 nM 10.6019/CHEMBL1201861
Homo sapiens Lu-65 IC50 26853.52 nM 10.6019/CHEMBL1201861
Homo sapiens LU-99A Activity 0.462 None 10.1073/pnas.0707498104
Homo sapiens LXF-289 cell line IC50 31449.21 nM 10.6019/CHEMBL1201861
Homo sapiens M059J Activity 0.762 None 10.1073/pnas.0707498104
Homo sapiens M14 Activity 0.576 None 10.1073/pnas.0707498104
Homo sapiens M14 GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens M14 GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens M14 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens M14 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens M14 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens M14 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens M14 LC50 25100.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens M14 TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens M14 TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens M14 TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens M14 TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens M14 TGI 5010.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens Macrophage colony stimulating factor receptor IC50 19.0 nM 10.1021/jm801050k
Homo sapiens Macrophage colony stimulating factor receptor IC50 58.0 nM 10.1021/jm901132v
Homo sapiens Macrophage colony stimulating factor receptor Kd 28.0 nM 10.1016/j.ejmech.2020.112421
Homo sapiens Macrophage colony stimulating factor receptor Kd 28.0 nM 10.1038/nbt1358
Homo sapiens Macrophage colony stimulating factor receptor Kd 28.0 nM 10.1038/nbt.1990
Homo sapiens Macrophage colony stimulating factor receptor Kd 28.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Macrophage colony stimulating factor receptor Ki 158.49 nM None
Homo sapiens Macrophage-stimulating protein receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Macrophage-stimulating protein receptor Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Macrophage-stimulating protein receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Macrophage-stimulating protein receptor Ki 3981.07 nM None
Homo sapiens Mahlavu IC50 13400.0 nM 10.1021/acs.jmedchem.2c00573
Homo sapiens Malate dehydrogenase, mitochondrial Inhibition 40.0 % 10.1021/acs.jmedchem.0c02253
Homo sapiens Malate dehydrogenase, mitochondrial Inhibition 80.0 % 10.1021/acs.jmedchem.0c02253
Homo sapiens Malate dehydrogenase, mitochondrial Inhibition 100.0 % 10.1021/acs.jmedchem.0c02253
Homo sapiens Malate dehydrogenase, mitochondrial Inhibition nan % 10.1021/acs.jmedchem.0c02253
Homo sapiens Malate dehydrogenase, mitochondrial TIME 0.25 hr 10.1021/acs.jmedchem.0c02253
Homo sapiens Malme-3M GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens Malme-3M GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens Malme-3M GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens Malme-3M IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens Malme-3M IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens Malme-3M LC50 63100.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens Malme-3M TGI 6310.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens Malme-3M TGI 39810.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens Malme-3M TGI 39810.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens Malme-3M TGI 39810.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens Malme-3M TGI 39810.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MAP kinase-activated protein kinase 2 Activity 4.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens MAP kinase-activated protein kinase 2 Activity 104.0 % 10.1042/bj20070797
Homo sapiens MAP kinase-activated protein kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase-activated protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase-activated protein kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase-activated protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase-activated protein kinase 2 Ki 7943.28 nM None
Homo sapiens MAP kinase-activated protein kinase 3 Activity 92.0 % 10.1042/bj20070797
Homo sapiens MAP kinase-activated protein kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase-activated protein kinase 3 Ki 10000.0 nM None
Homo sapiens MAP kinase-activated protein kinase 5 Activity 84.0 % 10.1042/bj20070797
Homo sapiens MAP kinase-activated protein kinase 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase-activated protein kinase 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase-activated protein kinase 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase-activated protein kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase-activated protein kinase 5 Ki 1584.89 nM None
Homo sapiens MAP kinase ERK1 Activity -5.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens MAP kinase ERK1 Activity 92.0 % 10.1042/bj20070797
Homo sapiens MAP kinase ERK1 IC50 18.1 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens MAP kinase ERK1 Inhibition nan % 10.1016/j.bmc.2012.04.006
Homo sapiens MAP kinase ERK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase ERK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase ERK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase ERK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase ERK2 Activity -8.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens MAP kinase ERK2 Activity 91.0 % 10.1042/bj20070797
Homo sapiens MAP kinase ERK2 IC50 109.5 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens MAP kinase ERK2 Inhibition nan % 10.1016/j.bmc.2012.04.006
Homo sapiens MAP kinase ERK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase ERK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase ERK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase ERK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase ERK2 Ki 7943.28 nM None
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Activity 67.0 % 10.1042/bj20070797
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Inhibition nan % 10.1016/j.bmc.2018.05.004
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Kd 230.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Kd 230.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Kd 230.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 alpha Activity -46.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens MAP kinase p38 alpha Activity 14.0 % 10.1042/bj20070797
Homo sapiens MAP kinase p38 alpha IC50 37.4 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens MAP kinase p38 alpha IC50 38.0 nM 10.1016/j.bmc.2009.10.055
Homo sapiens MAP kinase p38 alpha IC50 38.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens MAP kinase p38 alpha IC50 38.0 nM 10.1021/acs.jmedchem.1c00700
Homo sapiens MAP kinase p38 alpha IC50 84.2 nM 10.1016/j.bmc.2009.10.055
Homo sapiens MAP kinase p38 alpha IC50 84.8 nM 10.1016/j.bmc.2010.05.063
Homo sapiens MAP kinase p38 alpha IC50 400.0 nM 10.1021/jm901297e
Homo sapiens MAP kinase p38 alpha IC50 1100.0 nM 10.1021/jm901297e
Homo sapiens MAP kinase p38 alpha IC50 3200.0 nM 10.1042/bj20070797
Homo sapiens MAP kinase p38 alpha Inhibition nan % 10.1016/j.bmc.2012.04.006
Homo sapiens MAP kinase p38 alpha Kd 260.0 nM 10.1038/nbt1068
Homo sapiens MAP kinase p38 alpha Kd 260.0 nM 10.1073/pnas.0707498104
Homo sapiens MAP kinase p38 alpha Kd 370.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase p38 alpha Kd 370.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 alpha Kd 370.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase p38 alpha Ki 15.85 nM None
Homo sapiens MAP kinase p38 beta Activity 22.0 % 10.1042/bj20070797
Homo sapiens MAP kinase p38 beta Kd 200.0 nM 10.1038/nbt1068
Homo sapiens MAP kinase p38 beta Kd 200.0 nM 10.1073/pnas.0707498104
Homo sapiens MAP kinase p38 beta Kd 230.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase p38 beta Kd 230.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 beta Kd 230.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase p38 delta Activity 61.0 % 10.1042/bj20070797
Homo sapiens MAP kinase p38 delta Kd 6600.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 delta Kd 6600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 delta Ki 7943.28 nM None
Homo sapiens MAP kinase p38 gamma Activity 68.0 % 10.1042/bj20070797
Homo sapiens MAP kinase p38 gamma Kd 7600.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase p38 gamma Kd 7600.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 gamma Kd 7600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 gamma Kd 9900.0 nM 10.1038/nbt1068
Homo sapiens MAP kinase p38 gamma Ki 6309.57 nM None
Homo sapiens MAP kinase signal-integrating kinase 2 Activity 40.0 % 10.1042/bj20070797
Homo sapiens MAP kinase signal-integrating kinase 2 IC50 262.0 nM 10.1016/j.bmc.2018.05.004
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 130.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 130.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 130.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 250.0 nM 10.1038/nbt1068
Homo sapiens MAP kinase signal-integrating kinase 2 Ki 316.23 nM None
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd nan None 10.1038/nbt1068
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Ki 7943.28 nM None
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Ki 5011.87 nM None
Homo sapiens Maternal embryonic leucine zipper kinase Activity 56.0 % 10.1042/bj20070797
Homo sapiens Maternal embryonic leucine zipper kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Maternal embryonic leucine zipper kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Maternal embryonic leucine zipper kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Maternal embryonic leucine zipper kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Maternal embryonic leucine zipper kinase Ki 1995.26 nM None
Homo sapiens MC116 IC50 32082.64 nM 10.6019/CHEMBL1201861
Homo sapiens MC-CAR IC50 587371.21 nM 10.6019/CHEMBL1201861
Homo sapiens MCF7 Activity 0.949 None 10.1073/pnas.0707498104
Homo sapiens MCF7 Activity nan None 10.1039/C8MD00089A
Homo sapiens MCF7 FC 34.2 None 10.1016/j.bmc.2019.07.042
Homo sapiens MCF7 GI 23.0 % 10.1016/j.ejmech.2014.11.008
Homo sapiens MCF7 GI50 2510.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens MCF7 GI50 2510.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MCF7 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MCF7 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MCF7 GI50 4980.0 nM 10.1016/j.ejmech.2021.113634
Homo sapiens MCF7 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens MCF7 IC50 4.33 ug.mL-1 10.1016/j.ejmech.2017.04.068
Homo sapiens MCF7 IC50 90.0 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens MCF7 IC50 190.0 nM 10.1016/j.bmc.2014.11.029
Homo sapiens MCF7 IC50 780.0 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens MCF7 IC50 1880.0 nM 10.1016/j.bmc.2015.01.006
Homo sapiens MCF7 IC50 2500.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens MCF7 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MCF7 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MCF7 IC50 2510.0 nM 10.1016/j.ejmech.2018.09.005
Homo sapiens MCF7 IC50 2780.0 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens MCF7 IC50 3070.0 nM 10.1039/C8MD00089A
Homo sapiens MCF7 IC50 3180.0 nM 10.1016/j.bmc.2017.09.003
Homo sapiens MCF7 IC50 3470.0 nM 10.1016/j.ejmech.2018.12.067
Homo sapiens MCF7 IC50 3510.0 nM 10.1016/j.bmc.2021.116384
Homo sapiens MCF7 IC50 3640.0 nM 10.1016/j.ejmech.2018.03.001
Homo sapiens MCF7 IC50 4210.0 nM 10.1016/j.ejmech.2016.03.033
Homo sapiens MCF7 IC50 4270.0 nM 10.1016/j.ejmech.2018.11.061
Homo sapiens MCF7 IC50 4330.0 nM 10.1016/j.ejmech.2019.06.063
Homo sapiens MCF7 IC50 5500.0 nM 10.1016/j.bmcl.2015.06.076
Homo sapiens MCF7 IC50 5500.0 nM 10.1016/j.ejmech.2020.113102
Homo sapiens MCF7 IC50 5600.0 nM 10.1039/d2md00065b
Homo sapiens MCF7 IC50 7210.0 nM 10.1016/j.bmc.2020.115872
Homo sapiens MCF7 IC50 7260.0 nM 10.1016/j.ejmech.2022.114661
Homo sapiens MCF7 IC50 7330.0 nM 10.1016/j.ejmech.2013.03.043
Homo sapiens MCF7 IC50 8830.0 nM 10.1016/j.bmc.2010.03.077
Homo sapiens MCF7 IC50 9120.0 nM 10.1016/j.bmc.2013.11.013
Homo sapiens MCF7 IC50 11340.0 nM 10.1016/j.ejmech.2013.06.055
Homo sapiens MCF7 IC50 14000.0 nM 10.1016/j.ejmech.2018.11.023
Homo sapiens MCF7 IC50 14000.0 nM 10.1016/j.ejmech.2019.03.012
Homo sapiens MCF7 IC50 15000.0 nM 10.1016/j.bmcl.2021.127788
Homo sapiens MCF7 IC50 38168.0 nM 10.1016/j.bmc.2019.06.001
Homo sapiens MCF7 IC50 43300.0 nM 10.1016/j.ejmech.2019.111700
Homo sapiens MCF7 IC50 10870000.0 nM 10.1016/j.bmc.2020.115599
Homo sapiens MCF7 IC50 nan None 10.1016/j.ejmech.2014.11.008
Homo sapiens MCF7 IC50 nan None 10.1016/j.ejmech.2015.12.032
Homo sapiens MCF7 Inhibition 90.0 % 10.1016/j.ejmech.2019.06.063
Homo sapiens MCF7 Inhibition 95.75 % 10.1016/j.ejmech.2017.04.068
Homo sapiens MCF7 LC50 50100.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MCF7 TGI 7940.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MCF7 TGI 7940.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MCF7 TGI 7940.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MCF7 TGI 7940.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MCF7 TGI 7940.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MCF7 TGI 9970.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens MC-IXC Activity 0.216 None 10.1073/pnas.0707498104
Homo sapiens MC-IXC Activity 0.22 None 10.1073/pnas.0707498104
Homo sapiens MC-IXC Activity 0.99 None 10.1073/pnas.0707498104
Homo sapiens MDA-MB-134-VI IC50 15413.06 nM 10.6019/CHEMBL1201861
Homo sapiens MDA-MB-157 Activity 0.914 None 10.1073/pnas.0707498104
Homo sapiens MDA-MB-231 Activity 1.073 None 10.1073/pnas.0707498104
Homo sapiens MDA-MB-231 Activity nan None 10.1021/acs.jmedchem.7b00701
Homo sapiens MDA-MB-231 EC50 1000.0 nM 10.1021/acs.jmedchem.6b00087
Homo sapiens MDA-MB-231 GI 79.61 % 10.1016/j.ejmech.2010.02.005
Homo sapiens MDA-MB-231 GI50 1260.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens MDA-MB-231 GI50 1260.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MDA-MB-231 GI50 1260.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MDA-MB-231 GI50 1260.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MDA-MB-231 GI50 4130.0 nM 10.1016/j.ejmech.2021.113634
Homo sapiens MDA-MB-231 IC50 940.0 nM 10.1016/j.ejmech.2014.07.099
Homo sapiens MDA-MB-231 IC50 940.0 nM 10.1016/j.ejmech.2014.10.022
Homo sapiens MDA-MB-231 IC50 1260.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MDA-MB-231 IC50 1260.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MDA-MB-231 IC50 2000.0 nM 10.1016/j.bmcl.2013.02.034
Homo sapiens MDA-MB-231 IC50 2500.0 nM 10.1016/j.bmcl.2012.02.029
Homo sapiens MDA-MB-231 IC50 2800.0 nM 10.1016/j.ejmech.2017.11.065
Homo sapiens MDA-MB-231 IC50 3080.0 nM 10.1016/j.ejmech.2016.02.071
Homo sapiens MDA-MB-231 IC50 3810.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens MDA-MB-231 IC50 4770.0 nM 10.1016/j.bmc.2010.03.077
Homo sapiens MDA-MB-231 IC50 5100.0 nM 10.1016/j.bmcl.2015.06.076
Homo sapiens MDA-MB-231 IC50 5100.0 nM 10.1016/j.ejmech.2020.113102
Homo sapiens MDA-MB-231 IC50 7180.0 nM 10.1016/j.bmc.2012.05.051
Homo sapiens MDA-MB-231 IC50 7620.0 nM 10.1016/j.ejmech.2010.02.005
Homo sapiens MDA-MB-231 IC50 8520.0 nM 10.1016/j.ejmech.2021.113812
Homo sapiens MDA-MB-231 IC50 11840.0 nM 10.1016/j.ejmech.2020.112457
Homo sapiens MDA-MB-231 IC50 14620.0 nM 10.1016/j.bmc.2013.11.052
Homo sapiens MDA-MB-231 IC50 14620.0 nM 10.1016/j.ejmech.2013.03.043
Homo sapiens MDA-MB-231 IC50 15800.0 nM 10.1016/j.bmcl.2019.126711
Homo sapiens MDA-MB-231 IC50 17380.0 nM 10.1016/j.ejmech.2019.06.054
Homo sapiens MDA-MB-231 IC50 17840.0 nM 10.1039/C4MD00536H
Homo sapiens MDA-MB-231 IC50 35000.0 nM 10.1016/j.bmc.2013.11.027
Homo sapiens MDA-MB-231 IC50 35000.0 nM 10.1039/C3MD00192J
Homo sapiens MDA-MB-231 IC50 36000.0 nM 10.1016/j.bmc.2012.03.018
Homo sapiens MDA-MB-231 IC50 36600.0 nM 10.1007/s00044-012-0400-8
Homo sapiens MDA-MB-231 Inhibition 5.45 % 10.1016/j.ejmech.2020.112205
Homo sapiens MDA-MB-231 Inhibition nan % 10.1016/j.ejmech.2020.112457
Homo sapiens MDA-MB-231 LC50 20000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MDA-MB-231 TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MDA-MB-231 TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MDA-MB-231 TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MDA-MB-231 TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MDA-MB-231 TGI 3980.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MDA-MB-231 TGI 23930.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens MDA-MB-361 Activity 1.281 None 10.1073/pnas.0707498104
Homo sapiens MDA-MB-415 Activity 1.068 None 10.1073/pnas.0707498104
Homo sapiens MDA-MB-435 GI 91.89 % 10.1021/acs.jmedchem.7b01091
Homo sapiens MDA-MB-435 GI50 1580.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens MDA-MB-435 GI50 1580.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MDA-MB-435 GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MDA-MB-435 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MDA-MB-435 IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MDA-MB-435 IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MDA-MB-435 IC50 1670.0 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens MDA-MB-435 IC50 1950.0 nM 10.1016/j.bmc.2020.115897
Homo sapiens MDA-MB-435 IC50 2110.0 nM 10.1021/acs.jmedchem.7b01091
Homo sapiens MDA-MB-435 LC50 10000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MDA-MB-435 TGI 3980.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MDA-MB-435 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MDA-MB-435 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MDA-MB-435 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MDA-MB-435 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MDA-MB-436 IC50 4200.0 nM 10.1016/j.ejmech.2017.11.065
Homo sapiens MDA-MB-453 Activity 0.91 None 10.1073/pnas.0707498104
Homo sapiens MDA-MB-453 GI 36.9 % 10.1016/j.ejmech.2014.11.008
Homo sapiens MDA-MB-453 IC50 nan None 10.1016/j.ejmech.2014.11.008
Homo sapiens MDA-MB-468 Activity 1.068 None 10.1073/pnas.0707498104
Homo sapiens MDA-MB-468 GI50 1990.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens MDA-MB-468 GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens MDA-MB-468 GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MDA-MB-468 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MDA-MB-468 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MDA-MB-468 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MDA-MB-468 IC50 2000.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens MDA-MB-468 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MDA-MB-468 IC50 4900.0 nM 10.1016/j.bmcl.2015.06.076
Homo sapiens MDA-MB-468 IC50 4900.0 nM 10.1016/j.ejmech.2020.113102
Homo sapiens MDA-MB-468 IC50 7310.0 nM 10.1016/j.bmc.2022.116805
Homo sapiens MDA-MB-468 IC50 12170.0 nM 10.1016/j.bmcl.2019.04.047
Homo sapiens MDA-MB-468 LC50 39800.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MDA-MB-468 LC50 50120.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens MDA-MB-468 TGI 5010.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens MDA-MB-468 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MDA-MB-468 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MDA-MB-468 TGI 7940.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MDA-MB-468 TGI 7940.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens MDA-MB-468 TGI 7940.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MDA-MB-468 TGI 13090.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens ME-180 Activity 0.566 None 10.1073/pnas.0707498104
Homo sapiens MEG-01 IC50 1809.8 nM 10.6019/CHEMBL1201861
Homo sapiens Melanocortin receptor 3 AC50 23237.8 nM 10.1038/s41467-023-40064-9
Homo sapiens MEL-HO Activity 0.751 None 10.1073/pnas.0707498104
Homo sapiens MEL-JUSO Activity 0.761 None 10.1073/pnas.0707498104
Homo sapiens Membrane-associated progesterone receptor component 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Menin/Histone-lysine N-methyltransferase MLL Potency 3162.3 nM None
Homo sapiens MeWo Activity 1.01 None 10.1073/pnas.0707498104
Homo sapiens MFE-280 Activity 0.559 None 10.1073/pnas.0707498104
Homo sapiens MFE-296 Activity 0.1 None 10.1073/pnas.0707498104
Homo sapiens MFE-296 Activity 0.104 None 10.1073/pnas.0707498104
Homo sapiens MFE-296 Activity 0.8 None 10.1073/pnas.0707498104
Homo sapiens MFH-ino IC50 2921.85 nM 10.6019/CHEMBL1201861
Homo sapiens MFM-223 IC50 370085.11 nM 10.6019/CHEMBL1201861
Homo sapiens MGC-803 IC50 7990.0 nM 10.1016/j.ejmech.2020.112661
Homo sapiens MGC-803 IC50 9200.0 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens MGC-803 IC50 19920.0 nM 10.1016/j.bmc.2017.10.027
Homo sapiens MGC-803 IC50 50780.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens MHCC97 Activity nan None 10.1021/acs.jmedchem.1c00018
Homo sapiens MHCC97H IC50 1.3 mg kg-1 10.1021/acs.jmedchem.2c01070
Homo sapiens MHCC97H IC50 9320.0 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens MHH-CALL-2 IC50 37182.12 nM 10.6019/CHEMBL1201861
Homo sapiens MHH-NB-11 IC50 57714.88 nM 10.6019/CHEMBL1201861
Homo sapiens MHH-PREB-1 IC50 4404.84 nM 10.6019/CHEMBL1201861
Homo sapiens MIA PaCa-2 Activity 1.021 None 10.1073/pnas.0707498104
Homo sapiens MIA PaCa-2 IC50 9320.0 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens Microtubule-associated serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Microtubule-associated serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Midasin Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Misshapen-like kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Misshapen-like kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Misshapen-like kinase 1 Ki 1584.89 nM None
Homo sapiens Mitogen-activated protein kinase 15 Activity 7.0 % 10.1042/bj20070797
Homo sapiens Mitogen-activated protein kinase 15 Kd 46.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 15 Kd 46.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 15 Kd 46.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase 15 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase 7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase; ERK1/ERK2 Inhibition nan % 10.1016/j.ejmech.2013.06.060
Homo sapiens Mitogen-activated protein kinase kinase kinase 1 Kd 3783.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 10 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 10 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 10 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 10 Ki 3162.28 nM None
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 12 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 13 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 13 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 15 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 15 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd nan None 10.1038/nbt1068
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd nan None 10.1038/nbt1068
Homo sapiens Mitogen-activated protein kinase kinase kinase 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 K 0.0058 /s 10.1016/j.bmcl.2016.12.064
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 K 0.018 /s 10.1016/j.bmcl.2016.12.064
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 K 1.4 10'4/M/s 10.1016/j.bmcl.2016.12.064
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 K 9.6 10'3/M/s 10.1016/j.bmcl.2016.12.064
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 Kd 600.0 nM 10.1016/j.bmcl.2016.12.064
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 Kd 690.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 Kd 690.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 Kd 1300.0 nM 10.1016/j.bmcl.2016.12.064
Homo sapiens Mitogen-activated protein kinase kinase kinase 9 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 9 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 9 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 4800.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Ki 5011.87 nM None
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 4800.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 4800.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 4800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Ki 3162.28 nM None
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 1600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 1700.0 nM 10.1038/nbt1068
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Ki 316.23 nM None
Homo sapiens Mitotic checkpoint serine/threonine-protein kinase BUB1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mixed lineage kinase 7 Kd 6.3 nM 10.1038/nbt1358
Homo sapiens Mixed lineage kinase 7 Kd 6.3 nM 10.1038/nbt.1990
Homo sapiens Mixed lineage kinase 7 Kd 6.3 nM 10.1182/blood-2009-05-222034
Homo sapiens Mixed lineage kinase 7 Kd 729.0 nM 10.1126/science.aan4368
Homo sapiens Mixed lineage kinase 7 Ki 15.85 nM None
Homo sapiens MKN-28 Activity 0.957 None 10.1073/pnas.0707498104
Homo sapiens MKN-28 IC50 17000.0 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens MKN-45 Activity 0.992 None 10.1073/pnas.0707498104
Homo sapiens MKN-45 IC50 2320.0 nM 10.1016/j.ejmech.2018.09.005
Homo sapiens MKN-7 Activity 0.92 None 10.1073/pnas.0707498104
Homo sapiens MKN-74 Activity 0.612 None 10.1073/pnas.0707498104
Homo sapiens ML-2 IC50 6528.49 nM 10.6019/CHEMBL1201861
Homo sapiens MLMA IC50 191256.22 nM 10.6019/CHEMBL1201861
Homo sapiens MMAC-SF IC50 35878.53 nM 10.6019/CHEMBL1201861
Homo sapiens MN-60 IC50 384324.4 nM 10.6019/CHEMBL1201861
Homo sapiens Mo IC50 266748.16 nM 10.6019/CHEMBL1201861
Homo sapiens MOG-G-UVW Activity 1.346 None 10.1073/pnas.0707498104
Homo sapiens MOLM-13 Activity 5.16 % 10.1021/jm500118j
Homo sapiens MOLM-13 Activity 84.6 % 10.1021/jm500118j
Homo sapiens MOLM-13 GI50 56.0 nM 10.1016/j.bmc.2011.06.016
Homo sapiens MOLM-13 GI50 56.0 nM 10.1016/j.bmc.2013.03.083
Homo sapiens MOLM-13 GI50 56.0 nM 10.1016/j.bmcl.2012.05.116
Homo sapiens MOLM-13 IC50 5.0 nM 10.1021/jm500118j
Homo sapiens MOLM-13 IC50 8.7 nM 10.1016/j.bmc.2021.116596
Homo sapiens MOLM-13 IC50 3000.0 nM 10.1021/jm500118j
Homo sapiens MOLM-13 IC50 nan None 10.1016/j.bmc.2010.05.021
Homo sapiens MOLM-13 IC50 nan None 10.1016/j.bmc.2018.05.004
Homo sapiens MOLT-13 IC50 90128.37 nM 10.6019/CHEMBL1201861
Homo sapiens MOLT-16 IC50 6252.66 nM 10.6019/CHEMBL1201861
Homo sapiens MOLT-4 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MOLT-4 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens MOLT-4 GI50 9000.0 nM 10.1016/j.bmc.2011.06.016
Homo sapiens MOLT-4 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens MOLT-4 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MOLT-4 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MOLT-4 IC50 3160.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens MOLT-4 IC50 5940.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens MOLT-4 IC50 235053.0 nM 10.6019/CHEMBL1201861
Homo sapiens MOLT-4 TGI 100000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens MOLT-4 TGI 100000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens MOLT-4 TGI 100000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens MOLT-4 TGI 100000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens Monoamine oxidase A AC50 8258.3 nM 10.1038/s41467-023-40064-9
Homo sapiens MONO-MAC-6 IC50 4.181 nM 10.6019/CHEMBL1201861
Homo sapiens Mothers against decapentaplegic homolog 3 Potency 7079.5 nM None
Homo sapiens Motilin receptor AC50 2800.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MPP-89 IC50 159432.4 nM 10.6019/CHEMBL1201861
Homo sapiens MRC5 IC50 11100.0 nM 10.1016/j.bmc.2022.117048
Homo sapiens MRC5 IC50 24110.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens MRK-nu-1 IC50 3614.68 nM 10.6019/CHEMBL1201861
Homo sapiens MS-1 IC50 30727.78 nM 10.6019/CHEMBL1201861
Homo sapiens MSTO-211H Activity 1.187 None 10.1073/pnas.0707498104
Homo sapiens MSTO-211H IC50 53094.16 nM 10.6019/CHEMBL1201861
Homo sapiens Multifunctional protein ADE2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Kd 130.0 nM 10.1038/nbt1358
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Kd 130.0 nM 10.1038/nbt.1990
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Kd 130.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MV4-11 Activity 0.7 % 10.1016/j.ejmech.2011.07.045
Homo sapiens MV4-11 Activity 1.6 % 10.1016/j.ejmech.2011.07.045
Homo sapiens MV4-11 Activity 4.2 % 10.1016/j.ejmech.2018.11.063
Homo sapiens MV4-11 Activity 23.97 % 10.1021/acs.jmedchem.7b01261
Homo sapiens MV4-11 Activity 27.58 % 10.1016/j.ejmech.2018.11.063
Homo sapiens MV4-11 Activity 32.25 % 10.1016/j.ejmech.2018.11.063
Homo sapiens MV4-11 Activity 35.97 % 10.1016/j.ejmech.2018.11.063
Homo sapiens MV4-11 Activity 51.35 % 10.1021/acs.jmedchem.7b01261
Homo sapiens MV4-11 Activity 66.8 % 10.1021/acs.jnatprod.0c00589
Homo sapiens MV4-11 Activity nan None 10.1016/j.ejmech.2018.11.063
Homo sapiens MV4-11 Activity nan None 10.1021/acs.jmedchem.1c00459
Homo sapiens MV4-11 Activity nan None 10.1021/acs.jmedchem.7b01261
Homo sapiens MV4-11 GI 119.86 % 10.1016/j.ejmech.2019.05.021
Homo sapiens MV4-11 GI50 0.9 nM 10.1016/j.ejmech.2020.112205
Homo sapiens MV4-11 GI50 30.0 nM 10.1016/j.bmc.2011.06.016
Homo sapiens MV4-11 GI50 43.0 nM 10.1016/j.bmc.2013.03.083
Homo sapiens MV4-11 IC50 0.003034 nM 10.6019/CHEMBL1201861
Homo sapiens MV4-11 IC50 0.87 nM 10.1021/jm9007533
Homo sapiens MV4-11 IC50 0.87 nM 10.1039/C1MD00175B
Homo sapiens MV4-11 IC50 0.87 nM 10.1182/blood-2009-05-222034
Homo sapiens MV4-11 IC50 1.59 nM 10.1016/j.ejmech.2019.05.021
Homo sapiens MV4-11 IC50 4.0 nM 10.1021/acs.jmedchem.7b01261
Homo sapiens MV4-11 IC50 6.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens MV4-11 IC50 7.0 nM 10.1016/j.bmcl.2015.08.068
Homo sapiens MV4-11 IC50 7.7 nM 10.1016/j.bmc.2021.116596
Homo sapiens MV4-11 IC50 15.0 nM 10.1016/j.bmc.2010.05.021
Homo sapiens MV4-11 IC50 300.0 nM 10.1016/j.ejmech.2017.02.041
Homo sapiens MV4-11 IC50 300.0 nM 10.1016/j.ejmech.2018.11.033
Homo sapiens MV4-11 IC50 510.0 nM 10.1016/j.bmcl.2019.04.047
Homo sapiens MV4-11 Inhibition 93.19 % 10.1016/j.ejmech.2019.05.021
Homo sapiens MV4-11 T/C 10.1 % 10.1016/j.ejmech.2019.05.021
Homo sapiens MX1 IC50 8270.0 nM 10.1016/j.ejmech.2014.03.020
Homo sapiens MX1 IC50 8270.0 nM 10.1016/j.ejmech.2018.09.005
Homo sapiens Myosin-10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Myosin-14 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Myosin IIIA Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin IIIA Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin IIIA Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin-IIIB Kd 7100.0 nM 10.1038/nbt.1990
Homo sapiens Myosin-IIIB Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin-IIIB Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin light chain kinase Kd 9600.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens myosin light chain kinase 2 Kd 1300.0 nM 10.1038/nbt1068
Homo sapiens myosin light chain kinase 2 Kd 5400.0 nM 10.1038/nbt.1990
Homo sapiens myosin light chain kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens myosin light chain kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin light chain kinase family member 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin light chain kinase family member 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase family member 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin light chain kinase, smooth muscle Activity 84.0 % 10.1042/bj20070797
Homo sapiens Myosin light chain kinase, smooth muscle Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin light chain kinase, smooth muscle Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase, smooth muscle Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin light chain kinase, smooth muscle Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Myotonin-protein kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myotonin-protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myotonin-protein kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MZ1-PC IC50 3475.09 nM 10.6019/CHEMBL1201861
Homo sapiens MZ2-MEL IC50 6318.39 nM 10.6019/CHEMBL1201861
Homo sapiens MZ7-mel IC50 3660.99 nM 10.6019/CHEMBL1201861
Homo sapiens NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens NALM-6 IC50 217078.71 nM 10.6019/CHEMBL1201861
Homo sapiens NB1 IC50 7404.07 nM 10.6019/CHEMBL1201861
Homo sapiens NB10 IC50 50736.78 nM 10.6019/CHEMBL1201861
Homo sapiens NB12 IC50 63510.61 nM 10.6019/CHEMBL1201861
Homo sapiens NB13 IC50 25026.52 nM 10.6019/CHEMBL1201861
Homo sapiens NB14 IC50 8631.33 nM 10.6019/CHEMBL1201861
Homo sapiens NB17 IC50 211196.08 nM 10.6019/CHEMBL1201861
Homo sapiens NB5 IC50 359780.46 nM 10.6019/CHEMBL1201861
Homo sapiens NB6 IC50 9760.29 nM 10.6019/CHEMBL1201861
Homo sapiens NB69 Activity 0.61 None 10.1073/pnas.0707498104
Homo sapiens NB69 IC50 304957.98 nM 10.6019/CHEMBL1201861
Homo sapiens NB7 IC50 10752.58 nM 10.6019/CHEMBL1201861
Homo sapiens NCCIT IC50 488703.03 nM 10.6019/CHEMBL1201861
Homo sapiens NCI/ADR-RES GI50 2510.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens NCI/ADR-RES GI50 2510.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens NCI/ADR-RES GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI/ADR-RES GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI/ADR-RES IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI/ADR-RES IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI/ADR-RES LC50 100000.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens NCI/ADR-RES TGI 7940.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI/ADR-RES TGI 7940.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI/ADR-RES TGI 7940.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI/ADR-RES TGI 7940.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI/ADR-RES TGI 15800.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens NCI-H1048 Activity 0.683 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1092 IC50 222774.71 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1155 IC50 285380.11 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H128 IC50 327845.35 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1299 Activity 0.464 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1299 IC50 13291.06 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1304 IC50 110960.14 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1355 IC50 303349.01 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1395 IC50 46475.63 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1417 IC50 5840.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H1417 IC50 213367.49 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1436 IC50 1216.78 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1437 Activity 0.936 None 10.1073/pnas.0707498104
Homo sapiens NCI-H146 IC50 8010.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H1522 IC50 12745.98 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1563 Activity 1.112 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1573 Activity 1.088 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1581 Activity 0.19 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1581 Activity 0.192 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1581 Activity 0.86 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1581 IC50 4287.98 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1623 Activity 0.994 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1648 IC50 63572.31 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1650 Activity 0.92 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1650 IC50 18090.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H1651 Activity 1.002 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1666 Activity 0.97 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1693 Activity 0.794 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1694 IC50 14481.07 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1703 Activity 0.416 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1734 Activity 0.995 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1755 Activity 0.765 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1770 IC50 229807.27 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1792 Activity 0.763 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1793 Activity 0.948 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1838 IC50 354705.55 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H187 IC50 96674.34 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1882 IC50 13855.55 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1963 IC50 35307.2 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1975 Activity 0.941 None 10.1073/pnas.0707498104
Homo sapiens NCI-H1975 EC50 1000.0 nM 10.1021/acs.jmedchem.6b00087
Homo sapiens NCI-H1975 IC50 9270.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H2009 Activity 1.0 None 10.1073/pnas.0707498104
Homo sapiens NCI-H2029 Activity 0.559 None 10.1073/pnas.0707498104
Homo sapiens NCI-H2030 Activity 0.915 None 10.1073/pnas.0707498104
Homo sapiens NCI-H2081 IC50 77019.53 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2087 Activity 0.658 None 10.1073/pnas.0707498104
Homo sapiens NCI-H209 IC50 47140.52 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2107 IC50 51237.77 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H211 IC50 16470.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H2122 Activity 0.891 None 10.1073/pnas.0707498104
Homo sapiens NCI-H2126 IC50 335082.58 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2141 IC50 16188.97 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2170 Activity 0.704 None 10.1073/pnas.0707498104
Homo sapiens NCI-H2170 IC50 22590.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H2171 IC50 2397.64 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2196 Activity 0.746 None 10.1073/pnas.0707498104
Homo sapiens NCI-H2196 IC50 33255.69 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2227 IC50 30980.59 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2228 Activity 0.919 None 10.1073/pnas.0707498104
Homo sapiens NCI-H226 GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens NCI-H226 GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H226 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H226 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H226 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H226 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H226 IC50 7920.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H226 IC50 670868.4 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H226 LC50 31600.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H226 TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H226 TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H226 TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H226 TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H226 TGI 7940.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H226 TGI 14420.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens NCI-H23 Activity 0.724 None 10.1073/pnas.0707498104
Homo sapiens NCI-H23 GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens NCI-H23 GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H23 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H23 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H23 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H23 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H23 IC50 21399.15 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H23 LC50 39800.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H23 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H23 TGI 5010.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H23 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H23 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H23 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H2342 Activity 0.838 None 10.1073/pnas.0707498104
Homo sapiens NCI-H2347 Activity 0.836 None 10.1073/pnas.0707498104
Homo sapiens NCI-H2405 Activity 0.845 None 10.1073/pnas.0707498104
Homo sapiens NCI-H2452 Activity 0.829 None 10.1073/pnas.0707498104
Homo sapiens NCI-H322M GI50 2510.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens NCI-H322M GI50 2510.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H322M GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H322M GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H322M IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H322M IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H322M IC50 2510.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens NCI-H322M IC50 323762.43 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H322M LC50 50100.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H322M TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H322M TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H322M TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H322M TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H322M TGI 10000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H345 IC50 211579.75 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H358 Activity 0.492 None 10.1073/pnas.0707498104
Homo sapiens NCI-H441 Activity 0.826 None 10.1073/pnas.0707498104
Homo sapiens NCI-H446 IC50 473256.25 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H460 Activity 0.906 None 10.1073/pnas.0707498104
Homo sapiens NCI-H460 GI50 2510.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens NCI-H460 GI50 2510.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H460 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H460 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H460 IC50 2150.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens NCI-H460 IC50 2190.0 nM 10.1016/j.ejmech.2018.09.005
Homo sapiens NCI-H460 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H460 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H460 IC50 3680.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H460 IC50 3900.0 nM 10.1016/j.bmcl.2013.02.034
Homo sapiens NCI-H460 IC50 nan None 10.1016/j.ejmech.2015.12.032
Homo sapiens NCI-H460 LC50 39800.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H460 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H460 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H460 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H460 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H460 TGI 10000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H510A IC50 5416.85 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H520 Activity 0.816 None 10.1073/pnas.0707498104
Homo sapiens NCI-H520 IC50 11500.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H522 Activity 1.104 None 10.1073/pnas.0707498104
Homo sapiens NCI-H522 GI 39.4 % 10.1016/j.ejmech.2014.11.008
Homo sapiens NCI-H522 GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens NCI-H522 GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H522 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H522 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H522 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H522 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H522 IC50 5010.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens NCI-H522 IC50 19260.0 nM 10.1016/j.ejmech.2014.11.008
Homo sapiens NCI-H522 LC50 25100.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H522 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens NCI-H522 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens NCI-H522 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens NCI-H522 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens NCI-H522 TGI 6310.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens NCI-H522 TGI 14820.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens NCI-H524 IC50 90354.34 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H526 Activity -91.1 % 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H526 Activity -79.7 % 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H526 IC50 14680.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H526 IC50 437514.57 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H596 Activity 0.98 None 10.1073/pnas.0707498104
Homo sapiens NCI-H630 Activity 0.952 None 10.1073/pnas.0707498104
Homo sapiens NCI-H64 IC50 343187.86 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H647 Activity 1.007 None 10.1073/pnas.0707498104
Homo sapiens NCI-H661 Activity 0.784 None 10.1073/pnas.0707498104
Homo sapiens NCI-H69 IC50 445243.8 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H716 IC50 99847.7 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H719 IC50 51689.88 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H720 IC50 120352.39 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H727 Activity 0.693 None 10.1073/pnas.0707498104
Homo sapiens NCI-H747 IC50 11121.6 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H748 IC50 49475.27 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H810 Activity 0.96 None 10.1073/pnas.0707498104
Homo sapiens NCI-H82 IC50 1770.0 nM 10.1021/acs.jmedchem.0c01733
Homo sapiens NCI-H82 IC50 45575.81 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H838 Activity 1.006 None 10.1073/pnas.0707498104
Homo sapiens NCI-H889 IC50 420596.1 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-N87 Activity 0.821 None 10.1073/pnas.0707498104
Homo sapiens NEC8 IC50 36583.45 nM 10.6019/CHEMBL1201861
Homo sapiens Nerve growth factor receptor Trk-A Kd 3600.0 nM 10.1038/nbt1068
Homo sapiens Nerve growth factor receptor Trk-A Kd 6300.0 nM 10.1038/nbt1358
Homo sapiens Nerve growth factor receptor Trk-A Kd 6300.0 nM 10.1038/nbt.1990
Homo sapiens Nerve growth factor receptor Trk-A Kd 6300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Nerve growth factor receptor Trk-A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Nerve growth factor receptor Trk-A Ki 1584.89 nM None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Kd 2100.0 nM 10.1038/nbt1358
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Kd 2100.0 nM 10.1038/nbt.1990
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Kd 2100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Ki 630.96 nM None
Homo sapiens Neutrophil IC50 0.9 ug.mL-1 10.1021/acs.jnatprod.6b01141
Homo sapiens Neutrophil IC50 1.5 ug.mL-1 10.1021/acs.jnatprod.6b01141
Homo sapiens NH-12 IC50 99646.71 nM 10.6019/CHEMBL1201861
Homo sapiens NH-6 Activity 0.704 None 10.1073/pnas.0707498104
Homo sapiens NKM-1 IC50 74.16 nM 10.6019/CHEMBL1201861
Homo sapiens NMC-G1 IC50 130185.71 nM 10.6019/CHEMBL1201861
Homo sapiens no-10 IC50 1617.26 nM 10.6019/CHEMBL1201861
Homo sapiens no-11 IC50 5735.68 nM 10.6019/CHEMBL1201861
Homo sapiens NOMO-1 IC50 4489.05 nM 10.6019/CHEMBL1201861
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 2300.0 nM 10.1038/nbt1358
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 2300.0 nM 10.1038/nbt.1990
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 2300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens NOS-1 IC50 563.6 nM 10.6019/CHEMBL1201861
Homo sapiens NT-3 growth factor receptor Kd 600.0 nM 10.1038/nbt1358
Homo sapiens NT-3 growth factor receptor Kd 600.0 nM 10.1038/nbt.1990
Homo sapiens NT-3 growth factor receptor Kd 600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens NT-3 growth factor receptor Ki 398.11 nM None
Homo sapiens NTERA-2-cl-D1 IC50 12027.84 nM 10.6019/CHEMBL1201861
Homo sapiens NUAK family SNF1-like kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens NUAK family SNF1-like kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens NUAK family SNF1-like kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens NUAK family SNF1-like kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens NUAK family SNF1-like kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens NUAK family SNF1-like kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Nucleolar GTP-binding protein 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens NUGC-3 Activity 1.094 None 10.1073/pnas.0707498104
Homo sapiens NUGC-4 Activity 0.906 None 10.1073/pnas.0707498104
Homo sapiens OAW-28 Activity 0.846 None 10.1073/pnas.0707498104
Homo sapiens OAW-42 Activity 0.852 None 10.1073/pnas.0707498104
Homo sapiens Obg-like ATPase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens OCI-AML2 IC50 6610.62 nM 10.6019/CHEMBL1201861
Homo sapiens OCUB-M IC50 106591.42 nM 10.6019/CHEMBL1201861
Homo sapiens OE19 Activity 1.004 None 10.1073/pnas.0707498104
Homo sapiens OE33 Activity 0.983 None 10.1073/pnas.0707498104
Homo sapiens OMC-1 IC50 247026.35 nM 10.6019/CHEMBL1201861
Homo sapiens ONS-76 IC50 27332.0 nM 10.6019/CHEMBL1201861
Homo sapiens OPM-2 IC50 39843.17 nM 10.6019/CHEMBL1201861
Homo sapiens OS-RC-2 IC50 7000.0 nM 10.1021/acs.jnatprod.7b00698
Homo sapiens OS-RC-2 IC50 7000.0 nM 10.1021/acs.jnatprod.7b01053
Homo sapiens OS-RC-2 IC50 9112.43 nM 10.6019/CHEMBL1201861
Homo sapiens OS-RC-2 IC50 14000.0 nM 10.1021/acs.jmedchem.9b00598
Homo sapiens OS-RC-2 IC50 15000.0 nM 10.1021/acs.jnatprod.8b00015
Homo sapiens OS-RC-2 IC50 16000.0 nM 10.1016/j.bmcl.2013.02.034
Homo sapiens OV-1063 Activity 1.032 None 10.1073/pnas.0707498104
Homo sapiens OVCAR-3 GI50 2951.21 nM 10.1016/j.bmc.2020.115897
Homo sapiens OVCAR-3 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens OVCAR-3 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens OVCAR-3 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens OVCAR-3 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens OVCAR-3 IC50 12000.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens OVCAR-3 TGI 3980.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens OVCAR-3 TGI 3980.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens OVCAR-3 TGI 3980.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens OVCAR-3 TGI 3980.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens OVCAR-4 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens OVCAR-4 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens OVCAR-4 IC50 2213.93 nM 10.6019/CHEMBL1201861
Homo sapiens OVCAR-4 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens OVCAR-4 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens OVCAR-4 IC50 3160.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens OVCAR-4 TGI 25120.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens OVCAR-4 TGI 25120.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens OVCAR-4 TGI 25120.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens OVCAR-4 TGI 25120.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens OVCAR-5 Activity 0.935 None 10.1073/pnas.0707498104
Homo sapiens OVCAR-5 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens OVCAR-5 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens OVCAR-5 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens OVCAR-5 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens OVCAR-5 TGI 6310.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens OVCAR-5 TGI 6310.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens OVCAR-5 TGI 6310.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens OVCAR-5 TGI 6310.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens OVCAR-8 Activity 1.017 None 10.1073/pnas.0707498104
Homo sapiens OVCAR-8 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens OVCAR-8 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens OVCAR-8 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens OVCAR-8 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens OVCAR-8 TGI 12590.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens OVCAR-8 TGI 12590.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens OVCAR-8 TGI 12590.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens OVCAR-8 TGI 12590.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens P30-OHK IC50 12547.92 nM 10.6019/CHEMBL1201861
Homo sapiens P31-FUJ IC50 525807.93 nM 10.6019/CHEMBL1201861
Homo sapiens PA-1 Activity 0.18 None 10.1073/pnas.0707498104
Homo sapiens PANC-1 Activity 1.034 None 10.1073/pnas.0707498104
Homo sapiens PANC-1 IC50 150.0 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens PANC-1 IC50 9320.0 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens PANC-1 IC50 11500.0 nM 10.1016/j.bmcl.2016.07.068
Homo sapiens PANC-1 IC50 20000.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens Panel breast (Carcinoma cell lines) GI50 2170.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Panel CNS (Carcinoma cell lines) GI50 2330.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Panel colon (Carcinoma cell lines) GI50 2190.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Panel leukemia (Carcinoma cell lines) GI50 2430.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Panel melanoma (Carcinoma cell lines) GI50 1870.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Panel ovarian (Carcinoma cell lines) GI50 2880.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Panel prostate (Carcinoma cell lines) GI50 2580.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Panel renal (Carcinoma cell lines) GI50 2940.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens PAS domain-containing serine/threonine-protein kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens PAS domain-containing serine/threonine-protein kinase Ki 1584.89 nM None
Homo sapiens PC-14 Activity 1.253 None 10.1073/pnas.0707498104
Homo sapiens PC-3 Activity 0.038 None 10.1073/pnas.0707498104
Homo sapiens PC-3 Activity 0.04 None 10.1073/pnas.0707498104
Homo sapiens PC-3 Activity 1.0 None 10.1073/pnas.0707498104
Homo sapiens PC-3 Activity 1.92 % 10.1016/j.ejmech.2020.112942
Homo sapiens PC-3 Activity 16.6 % 10.1016/j.ejmech.2020.112942
Homo sapiens PC-3 Activity 22.32 % 10.1016/j.ejmech.2020.112942
Homo sapiens PC-3 Activity 23.6 % 10.1016/j.ejmech.2020.112942
Homo sapiens PC-3 Activity 57.9 % 10.1016/j.ejmech.2020.112942
Homo sapiens PC-3 Activity 66.19 % 10.1016/j.ejmech.2020.112942
Homo sapiens PC-3 GI 91.4 % 10.1007/s00044-012-0398-y
Homo sapiens PC-3 GI50 1990.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens PC-3 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens PC-3 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens PC-3 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens PC-3 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens PC-3 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens PC-3 IC50 3180.0 nM 10.1016/j.bmc.2017.09.003
Homo sapiens PC-3 IC50 4130.0 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens PC-3 IC50 6300.0 nM 10.1016/j.bmc.2021.116454
Homo sapiens PC-3 IC50 6800.0 nM 10.1016/j.bmcl.2012.09.031
Homo sapiens PC-3 IC50 9770.0 nM 10.1016/j.ejmech.2020.112457
Homo sapiens PC-3 IC50 11530.0 nM 10.1016/j.ejmech.2022.114661
Homo sapiens PC-3 IC50 15500.0 nM 10.1016/j.ejmech.2020.112942
Homo sapiens PC-3 IC50 24200.0 nM 10.1016/j.bmc.2013.11.052
Homo sapiens PC-3 IC50 24200.0 nM 10.1016/j.ejmech.2013.03.043
Homo sapiens PC-3 Inhibition 32.98 % 10.1016/j.ejmech.2020.112205
Homo sapiens PC-3 LC50 100000.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens PC-3 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens PC-3 TGI 5010.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens PC-3 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens PC-3 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens PC-3 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens PC-9 Activity 0.892 None 10.1073/pnas.0707498104
Homo sapiens PDZ-binding kinase Ki 10000.0 nM None
Homo sapiens Peripheral plasma membrane protein CASK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Peroxisomal acyl-coenzyme A oxidase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Peroxisomal acyl-coenzyme A oxidase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens PF-382 IC50 21440.31 nM 10.6019/CHEMBL1201861
Homo sapiens Phenylalanine--tRNA ligase beta subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 beta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphofructokinase platelet type Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd nan None 10.1038/nbt1068
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd nan None 10.1038/nbt1068
Homo sapiens Phosphorylase kinase gamma subunit 2 Ki 5011.87 nM None
Homo sapiens PI3-kinase p110-alpha subunit IC50 50000.0 nM 10.1038/nchembio.117
Homo sapiens PI3-kinase p110-alpha subunit IC50 nan None 10.1016/j.ejmech.2014.07.099
Homo sapiens PI3-kinase p110-alpha subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens PI3-kinase p110-alpha subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-alpha subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI3-kinase p110-beta subunit IC50 50000.0 nM 10.1038/nchembio.117
Homo sapiens PI3-kinase p110-beta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-beta subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI3-kinase p110-delta subunit IC50 50000.0 nM 10.1038/nchembio.117
Homo sapiens PI3-kinase p110-delta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-delta subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI3-kinase p110-gamma subunit IC50 50000.0 nM 10.1038/nchembio.117
Homo sapiens PI3-kinase p110-gamma subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-gamma subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI4-kinase beta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI4-kinase beta subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI4-kinase beta subunit Kd nan None 10.1039/C5MD00462D
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Plasma Cp 10.0 uM 10.1016/j.ejmech.2017.03.034
Homo sapiens Platelet-derived growth factor receptor alpha Activity -55.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Platelet-derived growth factor receptor alpha IC50 427.0 nM 10.1016/j.ejmech.2020.113081
Homo sapiens Platelet-derived growth factor receptor alpha Inhibition 99.39 % 10.1016/j.ejmech.2020.113081
Homo sapiens Platelet-derived growth factor receptor alpha Kd 62.0 nM 10.1016/j.ejmech.2020.112421
Homo sapiens Platelet-derived growth factor receptor alpha Kd 62.0 nM 10.1038/nbt1358
Homo sapiens Platelet-derived growth factor receptor alpha Kd 62.0 nM 10.1038/nbt.1990
Homo sapiens Platelet-derived growth factor receptor alpha Kd 62.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Platelet-derived growth factor receptor alpha Ki 1000.0 nM None
Homo sapiens Platelet-derived growth factor receptor beta IC50 10.0 nM 10.1021/jm801050k
Homo sapiens Platelet-derived growth factor receptor beta IC50 18.4 nM None
Homo sapiens Platelet-derived growth factor receptor beta IC50 37.0 nM 10.1021/jm300338m
Homo sapiens Platelet-derived growth factor receptor beta IC50 57.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Platelet-derived growth factor receptor beta IC50 57.0 nM 10.1021/acs.jmedchem.1c00678
Homo sapiens Platelet-derived growth factor receptor beta IC50 57.0 nM 10.1021/jm901132v
Homo sapiens Platelet-derived growth factor receptor beta IC50 57.0 nM 10.1038/nchembio799
Homo sapiens Platelet-derived growth factor receptor beta IC50 60.0 nM 10.1016/j.ejmech.2019.06.063
Homo sapiens Platelet-derived growth factor receptor beta IC50 90.0 nM 10.1016/j.ejmech.2021.113867
Homo sapiens Platelet-derived growth factor receptor beta IC50 130.0 nM 10.1016/j.ejmech.2018.11.061
Homo sapiens Platelet-derived growth factor receptor beta IC50 582.7 nM 10.1016/j.bmc.2019.06.001
Homo sapiens Platelet-derived growth factor receptor beta IC50 nan None 10.1016/j.ejmech.2014.07.099
Homo sapiens Platelet-derived growth factor receptor beta Inhibition 99.1 % 10.1016/j.ejmech.2020.113081
Homo sapiens Platelet-derived growth factor receptor beta Kd 37.0 nM 10.1038/nbt1358
Homo sapiens Platelet-derived growth factor receptor beta Kd 37.0 nM 10.1038/nbt.1990
Homo sapiens Platelet-derived growth factor receptor beta Kd 37.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Platelet-derived growth factor receptor beta Kd 41.0 nM 10.1038/nbt1068
Homo sapiens Platelet-derived growth factor receptor beta Kd 41.0 nM 10.1073/pnas.0707498104
Homo sapiens Platelet-derived growth factor receptor beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Platelet-derived growth factor receptor beta Ki 3.981 nM None
Homo sapiens PLC-PRF-5 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens PLC-PRF-5 IC50 7510.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens PLC-PRF-5 IC50 29900.0 nM 10.1016/j.ejmech.2017.01.008
Homo sapiens Pregnane X receptor AC50 18330.3 nM 10.1038/s41467-023-40064-9
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Probable ATP-dependent RNA helicase DDX6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein delta homolog 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C alpha Activity 87.0 % 10.1042/bj20070797
Homo sapiens Protein kinase C alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C alpha Kd nan None 10.1038/nbt1068
Homo sapiens Protein kinase C beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C delta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C delta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C delta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C delta Ki 7943.28 nM None
Homo sapiens Protein kinase C epsilon Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C epsilon Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C epsilon Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C eta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C eta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C eta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C gamma Ki 7943.28 nM None
Homo sapiens Protein kinase C iota Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C iota Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C mu Activity 90.0 % 10.1042/bj20070797
Homo sapiens Protein kinase C mu Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C mu Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C mu Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C nu Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C nu Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C nu Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C nu Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C nu Ki 6309.57 nM None
Homo sapiens Protein kinase C theta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C theta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C theta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C theta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C theta Ki 2511.89 nM None
Homo sapiens Protein kinase C zeta Activity 92.0 % 10.1042/bj20070797
Homo sapiens Protein kinase C zeta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C zeta Ki 7943.28 nM None
Homo sapiens Protein kinase N1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase N1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase N1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase N1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase N2 Activity 79.0 % 10.1042/bj20070797
Homo sapiens Protein kinase N2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase N2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase N2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase N2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase N2 Ki 7943.28 nM None
Homo sapiens Protein tyrosine kinase 2 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein tyrosine kinase 2 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein tyrosine kinase 2 beta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein tyrosine kinase 2 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein tyrosine kinase 2 beta Ki 1584.89 nM None
Homo sapiens Protein-tyrosine phosphatase 1C Activity nan None 10.1016/j.ejmech.2012.07.023
Homo sapiens Proto-oncogene tyrosine-protein kinase MER IC50 1370.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Kd 3600.0 nM 10.1038/nbt1358
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Kd 3600.0 nM 10.1038/nbt.1990
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Kd 3600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Ki 3162.28 nM None
Homo sapiens PSN1 IC50 65168.09 nM 10.6019/CHEMBL1201861
Homo sapiens Putative heat shock protein HSP 90-beta 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Putative uncharacterized serine/threonine-protein kinase SgK110 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Putative uncharacterized serine/threonine-protein kinase SgK110 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Pyridoxal kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens QIMR-WIL IC50 5072.94 nM 10.6019/CHEMBL1201861
Homo sapiens Quinone reductase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Rab-like protein 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Raji IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens Raji IC50 3940.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens Raji IC50 56962.04 nM 10.6019/CHEMBL1201861
Homo sapiens Ramos IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens Ramos IC50 nan None 10.1021/acs.jmedchem.7b01465
Homo sapiens Ramos-2G6-4C10 IC50 16129.73 nM 10.6019/CHEMBL1201861
Homo sapiens Ras-related protein Rab-10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ras-related protein Rab-27A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ras-related protein Rab-6A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens RCC10RGB IC50 162526.81 nM 10.6019/CHEMBL1201861
Homo sapiens RCM-1 Activity 1.023 None 10.1073/pnas.0707498104
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 IC50 1500.0 nM 10.1021/acs.jmedchem.2c01518
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 IC50 1500.0 nM 10.1021/acs.jmedchem.9b01317
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Receptor-interacting serine/threonine-protein kinase 3 IC50 14520.0 nM 10.1021/acs.jmedchem.9b01317
Homo sapiens Receptor-interacting serine/threonine-protein kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Receptor-interacting serine/threonine-protein kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor-interacting serine/threonine-protein kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Receptor protein-tyrosine kinase erbB-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Activity -1.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 130.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 131.0 nM 10.1016/j.ejmech.2022.114661
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd nan None 10.1038/nbt1068
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki 1584.89 nM None
Homo sapiens Receptor protein-tyrosine kinase erbB-4 Activity -60.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Receptor protein-tyrosine kinase erbB-4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor protein-tyrosine kinase erbB-4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Receptor protein-tyrosine kinase erbB-4 Ki 3981.07 nM None
Homo sapiens Receptor tyrosine-protein kinase erbB-3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor tyrosine-protein kinase erbB-3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens REH IC50 88391.07 nM 10.6019/CHEMBL1201861
Homo sapiens RERF-LC-MS Activity 0.725 None 10.1073/pnas.0707498104
Homo sapiens RH-1 IC50 97476.47 nM 10.6019/CHEMBL1201861
Homo sapiens Rho-associated protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Rho-associated protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Rho-associated protein kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Rho-associated protein kinase 1 Ki 3162.28 nM None
Homo sapiens Rho-associated protein kinase 2 Activity -23.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Rho-associated protein kinase 2 Activity 71.0 % 10.1042/bj20070797
Homo sapiens Rho-associated protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Rho-associated protein kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Rho-associated protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Rho-associated protein kinase 2 Ki 5011.87 nM None
Homo sapiens Rhodopsin kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Rhodopsin kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase 1 Activity 76.0 % 10.1042/bj20070797
Homo sapiens Ribosomal protein S6 kinase 1 Inhibition nan % 10.1038/nchembio.117
Homo sapiens Ribosomal protein S6 kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase 1 Ki 398.11 nM None
Homo sapiens Ribosomal protein S6 kinase alpha 1 Activity 41.0 % 10.1042/bj20070797
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd nan None 10.1038/nbt1068
Homo sapiens Ribosomal protein S6 kinase alpha 3 Activity 54.0 % 10.1042/bj20070797
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd nan None 10.1038/nbt1068
Homo sapiens Ribosomal protein S6 kinase alpha 3 Ki 3981.07 nM None
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 5 Activity 84.0 % 10.1042/bj20070797
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd nan None 10.1038/nbt1068
Homo sapiens Ribosomal protein S6 kinase alpha 5 Ki 1995.26 nM None
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 7500.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 7500.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 7500.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens RKO IC50 24180.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens RKO IC50 193502.03 nM 10.6019/CHEMBL1201861
Homo sapiens RL IC50 20969.16 nM 10.6019/CHEMBL1201861
Homo sapiens RL95-2 IC50 136323.13 nM 10.6019/CHEMBL1201861
Homo sapiens RNA cytidine acetyltransferase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens RO82-W-1 Activity 1.065 None 10.1073/pnas.0707498104
Homo sapiens RPMI-6666 IC50 68997.0 nM 10.6019/CHEMBL1201861
Homo sapiens RPMI-7951 Activity 0.805 None 10.1073/pnas.0707498104
Homo sapiens RPMI-8226 GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens RPMI-8226 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens RPMI-8226 IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens RPMI-8226 IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens RPMI-8226 IC50 7845.11 nM 10.6019/CHEMBL1201861
Homo sapiens RPMI-8226 TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens RPMI-8226 TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens RPMI-8226 TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens RPMI-8226 TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens RPMI 8402 IC50 98640.8 nM 10.6019/CHEMBL1201861
Homo sapiens RPMI-8866 IC50 46187.26 nM 10.6019/CHEMBL1201861
Homo sapiens RS4-11 IC50 393699.92 nM 10.6019/CHEMBL1201861
Homo sapiens RT-112 Activity 0.535 None 10.1073/pnas.0707498104
Homo sapiens RT-4 Activity 0.651 None 10.1073/pnas.0707498104
Homo sapiens RuvB-like 1 IC50 66000.0 nM 10.1016/j.bmc.2022.116726
Homo sapiens RuvB-like 2 IC50 66000.0 nM 10.1016/j.bmc.2022.116726
Homo sapiens RuvB-like 2 Kd 22000.0 nM 10.1016/j.bmc.2022.116726
Homo sapiens RVH-421 Activity 1.102 None 10.1073/pnas.0707498104
Homo sapiens RXF 393 GI50 2510.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens RXF 393 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens RXF 393 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens RXF 393 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens RXF 393 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens RXF 393 IC50 216435.37 nM 10.6019/CHEMBL1201861
Homo sapiens RXF 393 LC50 50100.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens RXF 393 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens RXF 393 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens RXF 393 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens RXF 393 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens RXF 393 TGI 10000.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens S-117 Activity 1.057 None 10.1073/pnas.0707498104
Homo sapiens S-adenosylmethionine synthase isoform type-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens SAOS-2 Activity 0.526 None 10.1073/pnas.0707498104
Homo sapiens SBC-1 IC50 142609.91 nM 10.6019/CHEMBL1201861
Homo sapiens SBC-3 Activity 0.98 None 10.1073/pnas.0707498104
Homo sapiens SBC-5 Activity 0.715 None 10.1073/pnas.0707498104
Homo sapiens SCaBER Activity 0.774 None 10.1073/pnas.0707498104
Homo sapiens SCC-15 IC50 17163.83 nM 10.6019/CHEMBL1201861
Homo sapiens SCC-3 IC50 166133.55 nM 10.6019/CHEMBL1201861
Homo sapiens SCCH-26 Activity 0.658 None 10.1073/pnas.0707498104
Homo sapiens SCH Activity 0.72 None 10.1073/pnas.0707498104
Homo sapiens SCH IC50 15472.77 nM 10.6019/CHEMBL1201861
Homo sapiens SCLC-21H Activity 0.93 None 10.1073/pnas.0707498104
Homo sapiens SCLC-21H IC50 52203.32 nM 10.6019/CHEMBL1201861
Homo sapiens Septin-9 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine-protein kinase ATR Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 10 Kd 140.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 10 Kd 140.0 nM 10.1073/pnas.0707498104
Homo sapiens Serine/threonine-protein kinase 10 Kd 150.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 10 Kd 150.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 10 Kd 150.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 11 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 11 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 11 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 11 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 16 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 16 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 16 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 16 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 16 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 17A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 17A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 17A Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 17A Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 17B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 17B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 17B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 17B Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 2 Kd 1000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 2 Kd 1000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 2 Kd 1000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 2 Kd 1600.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 2 Ki 1584.89 nM None
Homo sapiens Serine/threonine-protein kinase 24 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 24 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 24 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 24 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 25 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 25 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 25 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 32A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 32B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 32B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 32B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 32C Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 32C Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 32C Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 33 Kd 2400.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 33 Kd 2400.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 33 Kd 2400.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 35 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 35 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 36 Kd 3800.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 36 Kd 3800.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 36 Kd 3800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 36 Kd 5400.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 38 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 38 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 38-like Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 38-like Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 38-like Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 38-like Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase AKT Activity 94.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase AKT Inhibition nan % 10.1038/nchembio.117
Homo sapiens Serine/threonine-protein kinase AKT Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase AKT Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase AKT Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase AKT Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase AKT Ki 7943.28 nM None
Homo sapiens Serine/threonine-protein kinase AKT2 Activity 83.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase AKT2 Ki 7943.28 nM None
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase AKT3 Ki 10000.0 nM None
Homo sapiens Serine/threonine-protein kinase A-Raf IC50 7.1 nM 10.1016/j.ejmech.2017.02.041
Homo sapiens Serine/threonine-protein kinase A-Raf IC50 7.1 nM 10.1016/j.ejmech.2018.11.033
Homo sapiens Serine/threonine-protein kinase A-Raf IC50 12.0 nM 10.1016/j.bmcl.2019.04.047
Homo sapiens Serine/threonine-protein kinase A-Raf Inhibition 99.03 % 10.1016/j.ejmech.2020.113081
Homo sapiens Serine/threonine-protein kinase A-Raf Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Aurora-A IC50 3800.0 nM 10.1016/j.bmc.2011.06.016
Homo sapiens Serine/threonine-protein kinase Aurora-A IC50 3800.0 nM 10.1016/j.bmc.2013.03.083
Homo sapiens Serine/threonine-protein kinase Aurora-A IC50 3800.0 nM 10.1016/j.bmcl.2012.05.116
Homo sapiens Serine/threonine-protein kinase Aurora-A IC50 3800.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase Aurora-A Ki 794.33 nM None
Homo sapiens Serine/threonine-protein kinase Aurora-B Activity 15.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 440.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 440.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 440.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Aurora-B Ki 199.53 nM None
Homo sapiens Serine/threonine-protein kinase Aurora-C Activity 34.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd 210.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd 210.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd 210.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase B-raf Activity -92.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Serine/threonine-protein kinase B-raf Activity 30.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase B-raf Activity nan None 10.1021/acs.jmedchem.8b00499
Homo sapiens Serine/threonine-protein kinase B-raf EC50 3.0 nM 10.1073/pnas.0707498104
Homo sapiens Serine/threonine-protein kinase B-raf GI50 1000.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Serine/threonine-protein kinase B-raf IC50 1.0 nM 10.1016/j.bmcl.2010.12.039
Homo sapiens Serine/threonine-protein kinase B-raf IC50 1.0 nM 10.1021/jm801050k
Homo sapiens Serine/threonine-protein kinase B-raf IC50 4.4 nM 10.1021/acs.jmedchem.7b01306
Homo sapiens Serine/threonine-protein kinase B-raf IC50 12.0 nM 10.1016/j.ejmech.2014.07.099
Homo sapiens Serine/threonine-protein kinase B-raf IC50 12.0 nM 10.1016/j.ejmech.2014.10.022
Homo sapiens Serine/threonine-protein kinase B-raf IC50 12.7 nM None
Homo sapiens Serine/threonine-protein kinase B-raf IC50 13.0 nM 10.1016/j.bmcl.2013.05.011
Homo sapiens Serine/threonine-protein kinase B-raf IC50 14.0 nM 10.1016/j.bmcl.2008.04.002
Homo sapiens Serine/threonine-protein kinase B-raf IC50 15.0 nM 10.1016/j.bmcl.2008.04.002
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1016/j.bmc.2018.03.039
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1016/j.bmc.2018.12.032
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1016/j.bmc.2020.115493
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1016/j.bmcl.2011.10.012
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1016/j.ejmech.2020.113043
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1021/acs.jmedchem.1c00678
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1021/acs.jmedchem.7b00901
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1021/acs.jmedchem.7b01306
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1021/jm300613w
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.0 nM 10.1038/nchembio799
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.6 nM 10.1016/j.ejmech.2017.02.041
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22.6 nM 10.1016/j.ejmech.2018.11.033
Homo sapiens Serine/threonine-protein kinase B-raf IC50 24.0 nM 10.1016/j.bmc.2018.03.039
Homo sapiens Serine/threonine-protein kinase B-raf IC50 25.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Serine/threonine-protein kinase B-raf IC50 26.4 nM 10.1016/j.ejmech.2014.10.039
Homo sapiens Serine/threonine-protein kinase B-raf IC50 30.0 nM 10.1016/j.ejmech.2019.06.063
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.0 nM 10.1016/j.bmcl.2010.08.010
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.0 nM 10.1016/j.ejmech.2014.11.008
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.0 nM 10.1021/acs.jmedchem.1c00700
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.0 nM 10.1021/acs.jmedchem.7b00901
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.0 nM 10.1021/jm101479y
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.0 nM 10.1021/jm300613w
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.1 nM 10.1016/j.ejmech.2017.02.041
Homo sapiens Serine/threonine-protein kinase B-raf IC50 38.1 nM 10.1016/j.ejmech.2018.11.033
Homo sapiens Serine/threonine-protein kinase B-raf IC50 42.0 nM 10.1039/C3MD00096F
Homo sapiens Serine/threonine-protein kinase B-raf IC50 43.0 nM 10.1016/j.bmcl.2010.01.064
Homo sapiens Serine/threonine-protein kinase B-raf IC50 43.0 nM 10.1016/j.bmcl.2010.04.039
Homo sapiens Serine/threonine-protein kinase B-raf IC50 43.0 nM 10.1021/jm070776b
Homo sapiens Serine/threonine-protein kinase B-raf IC50 43.0 nM 10.1021/jm801509w
Homo sapiens Serine/threonine-protein kinase B-raf IC50 43.04 nM 10.1016/j.ejmech.2014.03.020
Homo sapiens Serine/threonine-protein kinase B-raf IC50 46.0 nM 10.1021/jm050983g
Homo sapiens Serine/threonine-protein kinase B-raf IC50 52.3 nM 10.1016/j.ejmech.2018.05.054
Homo sapiens Serine/threonine-protein kinase B-raf IC50 65.0 nM 10.1016/j.bmcl.2019.04.047
Homo sapiens Serine/threonine-protein kinase B-raf IC50 65.0 nM 10.1016/j.ejmech.2020.112904
Homo sapiens Serine/threonine-protein kinase B-raf IC50 76.2 nM 10.1016/j.bmc.2010.05.063
Homo sapiens Serine/threonine-protein kinase B-raf IC50 100.0 nM 10.1021/jm400045y
Homo sapiens Serine/threonine-protein kinase B-raf IC50 114.0 nM 10.1039/C3MD00096F
Homo sapiens Serine/threonine-protein kinase B-raf IC50 120.0 nM 10.1016/j.bmcl.2015.07.082
Homo sapiens Serine/threonine-protein kinase B-raf IC50 120.0 nM 10.1016/j.ejmech.2014.05.025
Homo sapiens Serine/threonine-protein kinase B-raf IC50 136.0 nM 10.1016/j.ejmech.2014.05.025
Homo sapiens Serine/threonine-protein kinase B-raf IC50 200.0 nM 10.1073/pnas.0707498104
Homo sapiens Serine/threonine-protein kinase B-raf IC50 310.0 nM 10.1016/j.bmc.2017.09.003
Homo sapiens Serine/threonine-protein kinase B-raf IC50 310.0 nM 10.1016/j.bmcl.2016.10.029
Homo sapiens Serine/threonine-protein kinase B-raf IC50 6100.0 nM 10.1021/jm050983g
Homo sapiens Serine/threonine-protein kinase B-raf IC50 6599.0 nM 10.1016/j.bmcl.2011.07.019
Homo sapiens Serine/threonine-protein kinase B-raf IC50 7300.0 nM 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase B-raf IC50 22000.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Serine/threonine-protein kinase B-raf Inhibition 51.91 % 10.1016/j.ejmech.2014.11.008
Homo sapiens Serine/threonine-protein kinase B-raf Inhibition 58.0 % 10.1016/j.bmc.2016.03.008
Homo sapiens Serine/threonine-protein kinase B-raf Inhibition 94.5 % 10.1016/j.ejmech.2018.05.054
Homo sapiens Serine/threonine-protein kinase B-raf Inhibition 95.7 % 10.1016/j.ejmech.2014.04.059
Homo sapiens Serine/threonine-protein kinase B-raf Inhibition 98.7 % 10.1016/j.ejmech.2020.113081
Homo sapiens Serine/threonine-protein kinase B-raf Inhibition 100.0 % 10.1016/j.ejmech.2016.02.071
Homo sapiens Serine/threonine-protein kinase B-raf Inhibition 100.0 % 10.1016/j.ejmech.2020.113081
Homo sapiens Serine/threonine-protein kinase B-raf Inhibition nan % 10.1016/j.ejmech.2015.10.045
Homo sapiens Serine/threonine-protein kinase B-raf Kd 260.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase B-raf Kd 260.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase B-raf Kd 260.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase B-raf Kd 284.0 nM 10.1016/j.bmcl.2011.07.019
Homo sapiens Serine/threonine-protein kinase B-raf Kd 540.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase B-raf Kd 540.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase B-raf Kd 540.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase B-raf Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase B-raf Ki 22.0 nM 10.1016/j.chembiol.2005.04.011
Homo sapiens Serine/threonine-protein kinase B-raf Ki 38.0 nM 10.1021/jm800539g
Homo sapiens Serine/threonine-protein kinase Chk1 Activity 89.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Chk1 Ki 6309.57 nM None
Homo sapiens Serine/threonine-protein kinase Chk2 Activity 99.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase Chk2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Chk2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Chk2 Ki 5011.87 nM None
Homo sapiens Serine/threonine-protein kinase c-TAK1 Activity 83.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase c-TAK1 Ki 5011.87 nM None
Homo sapiens Serine/threonine-protein kinase D2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase D2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase D2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase D2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase D2 Ki 10000.0 nM None
Homo sapiens Serine/threonine-protein kinase DCLK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase DCLK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase DCLK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase DCLK1 Ki 10000.0 nM None
Homo sapiens Serine/threonine-protein kinase DCLK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase DCLK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase DCLK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase DCLK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase DCLK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase DCLK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase EEF2K Activity 99.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase EEF2K Ki 3981.07 nM None
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase GAK Activity 90.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase GAK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase GAK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase GAK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase GAK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase GAK Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase ICK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ICK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase ICK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase ILK-1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase LATS2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase LATS2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase LATS2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MAK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MAK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MARK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MARK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MARK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MRCK-A Ki 10000.0 nM None
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MST1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MST1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MST1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MST1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MST1 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase MST2 Activity 91.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase MST2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MST2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MST2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MST2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MST2 Ki 6309.57 nM None
Homo sapiens Serine/threonine-protein kinase MST4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MST4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MST4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MST4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase mTOR IC50 50000.0 nM 10.1038/nchembio.117
Homo sapiens Serine/threonine-protein kinase mTOR IC50 nan None 10.1016/j.ejmech.2014.07.099
Homo sapiens Serine/threonine-protein kinase mTOR Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase N3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Nek11 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK2 Activity 92.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase NEK2 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase NEK2 Ki 6309.57 nM None
Homo sapiens Serine/threonine-protein kinase Nek3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Nek4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek4 Ki 6309.57 nM None
Homo sapiens Serine/threonine-protein kinase Nek5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Nek5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK6 Activity 92.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase NEK6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK6 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase NEK7 Activity 96.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase NEK7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase NEK9 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase NIM1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NIM1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine protein kinase NLK Kd 640.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine protein kinase NLK Kd 640.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine protein kinase NLK Kd 640.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine protein kinase NLK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase OSR1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase OSR1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PAK 1 Ki 10000.0 nM None
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PAK 4 Activity 89.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PAK 4 Ki 5011.87 nM None
Homo sapiens Serine/threonine-protein kinase PAK6 Activity 94.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase PAK6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK6 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PAK7 Activity 89.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase PAK7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK7 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 1600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PCTAIRE-3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PCTAIRE-3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PCTAIRE-3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PFTAIRE-1 Kd 2900.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PFTAIRE-1 Kd 2900.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PFTAIRE-1 Kd 2900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PFTAIRE-2 Kd 2900.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PFTAIRE-2 Kd 2900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PIM1 Activity 72.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PIM1 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PIM1 Kd nan None 10.1039/C5MD00462D
Homo sapiens Serine/threonine-protein kinase PIM1 Ki 6309.57 nM None
Homo sapiens Serine/threonine-protein kinase PIM2 Activity 98.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase PIM2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PIM2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PIM2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PIM2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PIM2 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PIM2 Ki 1584.89 nM None
Homo sapiens Serine/threonine-protein kinase PIM3 Activity 65.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase PIM3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PIM3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PIM3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PLK1 Activity 86.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase PLK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PLK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PLK1 Ki 7943.28 nM None
Homo sapiens Serine/threonine-protein kinase PLK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PLK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PLK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PLK3 Ki 7943.28 nM None
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 3400.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 4500.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 4500.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 4500.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PLK4 Ki 398.11 nM None
Homo sapiens Serine/threonine-protein kinase PRKX Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PRKX Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PRKX Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PRKX Ki 3162.28 nM None
Homo sapiens Serine/threonine-protein kinase PRP4 homolog Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PRP4 homolog Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RAF Activity 1.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase RAF IC50 1.0 nM 10.1021/jm801050k
Homo sapiens Serine/threonine-protein kinase RAF IC50 3.0 nM 10.1016/j.bmcl.2008.04.002
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1016/j.bmcl.2010.08.010
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1016/j.ejmech.2014.07.099
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1016/j.ejmech.2014.10.022
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1016/j.ejmech.2020.113043
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1021/acs.jmedchem.7b00901
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1021/jm101479y
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1021/jm300613w
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.0 nM 10.1021/jm901132v
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.2 nM 10.1016/j.ejmech.2017.02.041
Homo sapiens Serine/threonine-protein kinase RAF IC50 6.2 nM 10.1016/j.ejmech.2018.11.033
Homo sapiens Serine/threonine-protein kinase RAF IC50 7.0 nM 10.1016/j.ejmech.2019.06.063
Homo sapiens Serine/threonine-protein kinase RAF IC50 7.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens Serine/threonine-protein kinase RAF IC50 12.0 nM 10.1016/j.bmcl.2003.11.041
Homo sapiens Serine/threonine-protein kinase RAF IC50 12.0 nM 10.1016/j.ejmech.2008.09.016
Homo sapiens Serine/threonine-protein kinase RAF IC50 21.98 nM 10.1016/j.ejmech.2014.03.020
Homo sapiens Serine/threonine-protein kinase RAF IC50 24.3 nM 10.1016/j.bmc.2012.05.051
Homo sapiens Serine/threonine-protein kinase RAF IC50 40.0 nM 10.1016/j.bmcl.2011.02.108
Homo sapiens Serine/threonine-protein kinase RAF IC50 45.0 nM 10.1016/j.bmcl.2013.05.011
Homo sapiens Serine/threonine-protein kinase RAF IC50 45.0 nM None
Homo sapiens Serine/threonine-protein kinase RAF IC50 52.0 nM 10.1021/jm070776b
Homo sapiens Serine/threonine-protein kinase RAF IC50 52.0 nM 10.1021/jm300338m
Homo sapiens Serine/threonine-protein kinase RAF IC50 55.0 nM 10.1016/j.bmcl.2019.04.047
Homo sapiens Serine/threonine-protein kinase RAF IC50 120.0 nM 10.1016/j.bmc.2017.09.003
Homo sapiens Serine/threonine-protein kinase RAF IC50 370.0 nM 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase RAF Inhibition 28.5 % 10.1039/C2MD20275A
Homo sapiens Serine/threonine-protein kinase RAF Inhibition 50.0 % 10.1016/j.ejmech.2011.04.007
Homo sapiens Serine/threonine-protein kinase RAF Inhibition 97.3 % 10.1016/j.ejmech.2014.04.059
Homo sapiens Serine/threonine-protein kinase RAF Inhibition 99.64 % 10.1016/j.ejmech.2020.113081
Homo sapiens Serine/threonine-protein kinase RAF Inhibition 101.36 % 10.1016/j.bmc.2012.04.006
Homo sapiens Serine/threonine-protein kinase RAF Inhibition nan % 10.1016/j.ejmech.2015.10.045
Homo sapiens Serine/threonine-protein kinase RAF Kd 230.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RAF Kd 230.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RAF Kd 230.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RAF Ki 6.0 nM 10.1021/jm800539g
Homo sapiens Serine/threonine-protein kinase RAF and Dual specificity mitogen-activated protein kinase kinase 1 (Raf/MEK) IC50 3300.0 nM 10.1016/j.bmcl.2004.05.048
Homo sapiens Serine/threonine-protein kinase receptor R3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase receptor R3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase receptor R3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIO1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RIO1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIO1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIO2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIO2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIPK2 Activity 26.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase RIPK2 IC50 3600.0 nM 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 1300.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 1300.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 1300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 2900.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase SBK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Sgk1 Activity 90.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase Sgk2 Ki 7943.28 nM None
Homo sapiens Serine/threonine-protein kinase Sgk3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SIK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase SIK2 Ki 3981.07 nM None
Homo sapiens Serine/threonine-protein kinase SIK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SIK3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase SRPK1 Activity 88.0 % 10.1042/bj20070797
Homo sapiens Serine/threonine-protein kinase SRPK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SRPK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SRPK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SRPK1 Ki 5011.87 nM None
Homo sapiens Serine/threonine-protein kinase SRPK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SRPK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SRPK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SRPK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SRPK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase TAO1 Kd 540.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase TAO1 Kd 3100.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase TAO1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TAO1 Ki 398.11 nM None
Homo sapiens Serine/threonine-protein kinase TAO2 Kd 540.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TAO3 Kd 2700.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO3 Kd 2700.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase TAO3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TBK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TBK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase TBK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TBK1 Ki 3162.28 nM None
Homo sapiens Serine/threonine-protein kinase TNNI3K IC50 100.0 nM 10.1021/acs.jmedchem.1c00700
Homo sapiens Serine/threonine-protein kinase TNNI3K IC50 250.0 nM 10.1021/acs.jmedchem.1c00700
Homo sapiens Serine/threonine-protein kinase TNNI3K Kd 280.0 nM 10.1021/acs.jmedchem.1c00700
Homo sapiens Serine/threonine-protein kinase TNNI3K Kd 280.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase TNNI3K Kd 280.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TNNI3K Kd 280.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase tousled-like 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase tousled-like 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase tousled-like 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase ULK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase ULK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase ULK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase ULK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase ULK3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase VRK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor Ki 1181.0 nM 10.1021/jm300338m
Homo sapiens Serotonin 1b (5-HT1b) receptor Activity nan None 10.1021/jm300338m
Homo sapiens Serotonin 1e (5-HT1e) receptor Activity nan None 10.1021/jm300338m
Homo sapiens Serotonin 1f (5-HT1f) receptor Activity nan None 10.1021/jm300338m
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor Inhibition 93.3 % 10.1021/jm300338m
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki 1959.0 nM 10.1021/jm300338m
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki 56.0 nM 10.1021/jm300338m
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki 417.0 nM 10.1021/jm300338m
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 3a (5-HT3a) receptor Activity nan None 10.1021/jm300338m
Homo sapiens Serotonin 5a (5-HT5a) receptor Ki 3296.0 nM 10.1021/jm300338m
Homo sapiens Serotonin 6 (5-HT6) receptor Ki 6213.0 nM 10.1021/jm300338m
Homo sapiens Serotonin 7 (5-HT7) receptor Ki 7071.0 nM 10.1021/jm300338m
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens SF-126 IC50 1638.12 nM 10.6019/CHEMBL1201861
Homo sapiens SF-268 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SF-268 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SF-268 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SF-268 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SF-268 IC50 102242.25 nM 10.6019/CHEMBL1201861
Homo sapiens SF-268 TGI 3980.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SF-268 TGI 3980.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SF-268 TGI 3980.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SF-268 TGI 3980.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SF-295 Activity 0.812 None 10.1073/pnas.0707498104
Homo sapiens SF-295 GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SF-295 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SF-295 IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SF-295 IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SF-295 TGI 6310.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SF-295 TGI 6310.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SF-295 TGI 6310.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SF-295 TGI 6310.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SF-539 GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SF-539 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SF-539 IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SF-539 IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SF-539 IC50 5132.27 nM 10.6019/CHEMBL1201861
Homo sapiens SF-539 TGI 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SF-539 TGI 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SF-539 TGI 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SF-539 TGI 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SGC-7901 IC50 6900.0 nM 10.1016/j.bmcl.2013.02.034
Homo sapiens SGC-7901 IC50 8840.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens SGC-7901 IC50 10370.0 nM 10.1016/j.bmc.2010.03.077
Homo sapiens SGC-7901 IC50 nan None 10.1016/j.bmcl.2016.07.068
Homo sapiens SH-4 IC50 656.13 nM 10.6019/CHEMBL1201861
Homo sapiens SHP77 Activity 0.607 None 10.1073/pnas.0707498104
Homo sapiens SHP77 IC50 9716.62 nM 10.6019/CHEMBL1201861
Homo sapiens SH-SY5Y IC50 5730.0 nM 10.1039/C3MD00192J
Homo sapiens SH-SY5Y IC50 100000.0 nM 10.1016/j.bmc.2019.06.001
Homo sapiens SIG-M5 IC50 2422.42 nM 10.6019/CHEMBL1201861
Homo sapiens Signal transducer and activator of transcription 5A Inhibition nan % 10.1021/acsmedchemlett.2c00402
Homo sapiens SiHa Activity 0.764 None 10.1073/pnas.0707498104
Homo sapiens SIMA IC50 7001.01 nM 10.6019/CHEMBL1201861
Homo sapiens SISO Activity 0.873 None 10.1073/pnas.0707498104
Homo sapiens SJSA-1 IC50 143357.57 nM 10.6019/CHEMBL1201861
Homo sapiens SK-BR-3 Activity 0.715 None 10.1073/pnas.0707498104
Homo sapiens SK-BR-3 IC50 5210.0 nM 10.1039/C3MD00192J
Homo sapiens SK-CO-1 Activity 0.789 None 10.1073/pnas.0707498104
Homo sapiens SKG-IIIa Activity 0.38 None 10.1073/pnas.0707498104
Homo sapiens SK-HEP1 Activity 0.659 None 10.1073/pnas.0707498104
Homo sapiens SK-HEP1 Activity 1.01 % 10.1021/acs.jmedchem.2c00520
Homo sapiens SK-HEP1 Activity 1.32 % 10.1021/acs.jmedchem.2c00520
Homo sapiens SK-HEP1 Activity 3.5 % 10.1021/acs.jmedchem.2c00520
Homo sapiens SK-HEP1 Activity 5.43 % 10.1021/acs.jmedchem.2c00520
Homo sapiens SK-HEP1 Activity 34.1 % 10.1021/acs.jmedchem.2c00520
Homo sapiens SK-HEP1 Activity 60.47 % 10.1021/acs.jmedchem.2c00520
Homo sapiens SK-HEP1 Activity 94.1 % 10.1021/acs.jmedchem.2c00520
Homo sapiens SK-HEP1 Activity nan None 10.1021/acs.jmedchem.2c00520
Homo sapiens SK-HEP1 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens SK-HEP1 IC50 1980.0 nM 10.1021/acs.jmedchem.2c00520
Homo sapiens SK-HEP1 IC50 7300.0 nM 10.1016/j.bmc.2021.116454
Homo sapiens SK-HEP1 IC50 8370.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens SK-HEP1 IC50 9640.0 nM 10.1016/j.ejmech.2020.112581
Homo sapiens SK-LMS-1 IC50 86722.56 nM 10.6019/CHEMBL1201861
Homo sapiens SK-LU-1 Activity 0.405 None 10.1073/pnas.0707498104
Homo sapiens SKM-1 IC50 200849.12 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MEL Activity nan None 10.1021/acs.jnatprod.0c00840
Homo sapiens SK-MEL IC50 10000.0 nM 10.1021/acs.jnatprod.0c00840
Homo sapiens SK-MEL-1 IC50 17007.15 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MEL-2 GI50 1580.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens SK-MEL-2 GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SK-MEL-2 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SK-MEL-2 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SK-MEL-2 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SK-MEL-2 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SK-MEL-2 IC50 11350.0 nM 10.1016/j.ejmech.2017.02.041
Homo sapiens SK-MEL-2 IC50 11400.0 nM 10.1016/j.ejmech.2018.11.033
Homo sapiens SK-MEL-2 IC50 290279.72 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MEL-2 LC50 6310.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SK-MEL-2 TGI 3160.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SK-MEL-2 TGI 6310.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SK-MEL-2 TGI 6310.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SK-MEL-2 TGI 6310.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SK-MEL-2 TGI 6310.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SK-MEL-2 TGI 14850.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens SK-MEL-28 EC50 1300.0 nM 10.1021/jm801050k
Homo sapiens SK-MEL-28 GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens SK-MEL-28 GI50 2510.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SK-MEL-28 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SK-MEL-28 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SK-MEL-28 IC50 1950.0 nM 10.1016/j.bmc.2020.115897
Homo sapiens SK-MEL-28 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SK-MEL-28 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SK-MEL-28 IC50 9450.0 nM 10.1016/j.bmc.2019.03.062
Homo sapiens SK-MEL-28 LC50 31600.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SK-MEL-28 TGI 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SK-MEL-28 TGI 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SK-MEL-28 TGI 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SK-MEL-28 TGI 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SK-MEL-28 TGI 7940.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SK-MEL-28 TGI 13390.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens SK-MEL3 Activity 1.065 None 10.1073/pnas.0707498104
Homo sapiens SK-MEL-30 Activity 0.488 None 10.1073/pnas.0707498104
Homo sapiens SK-MEL-30 IC50 3900.0 nM 10.1021/acs.jmedchem.7b01306
Homo sapiens SK-MEL-5 GI50 1580.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens SK-MEL-5 GI50 1580.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SK-MEL-5 GI50 1580.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens SK-MEL-5 GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SK-MEL-5 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SK-MEL-5 IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SK-MEL-5 IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SK-MEL-5 IC50 2510.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens SK-MEL-5 LC50 5010.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SK-MEL-5 LC50 5010.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens SK-MEL-5 TGI 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SK-MEL-5 TGI 2510.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens SK-MEL-5 TGI 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SK-MEL-5 TGI 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SK-MEL-5 TGI 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SK-MEL-5 TGI 3160.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SK-MEL-5 TGI 31260.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens SK-MES-1 Activity 0.638 None 10.1073/pnas.0707498104
Homo sapiens SK-MES-1 Activity 0.987 None 10.1073/pnas.0707498104
Homo sapiens SK-MM-2 IC50 34945.06 nM 10.6019/CHEMBL1201861
Homo sapiens SK-N-AS Activity 0.257 None 10.1073/pnas.0707498104
Homo sapiens SK-N-AS Activity 0.26 None 10.1073/pnas.0707498104
Homo sapiens SK-N-AS Activity 0.88 None 10.1073/pnas.0707498104
Homo sapiens SK-N-DZ IC50 26341.4 nM 10.6019/CHEMBL1201861
Homo sapiens SK-NEP-1 Activity 0.999 None 10.1073/pnas.0707498104
Homo sapiens SK-NEP-1 IC50 4168.15 nM 10.6019/CHEMBL1201861
Homo sapiens SK-N-FI IC50 15653.4 nM 10.6019/CHEMBL1201861
Homo sapiens SK-N-SH Activity 0.503 None 10.1073/pnas.0707498104
Homo sapiens SK-OV-3 Activity 0.87 None 10.1073/pnas.0707498104
Homo sapiens SK-OV-3 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SK-OV-3 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SK-OV-3 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SK-OV-3 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SK-OV-3 IC50 9250.0 nM 10.1016/j.bmc.2013.11.013
Homo sapiens SK-OV-3 Inhibition 4.51 % 10.1016/j.ejmech.2020.112205
Homo sapiens SK-OV-3 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SK-OV-3 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SK-OV-3 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SK-OV-3 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SK-PN-DW IC50 65300.52 nM 10.6019/CHEMBL1201861
Homo sapiens SK-UT-1 IC50 310244.59 nM 10.6019/CHEMBL1201861
Homo sapiens SMMC-7721 Activity 343.4 mm3 10.1016/j.ejmech.2021.113670
Homo sapiens SMMC-7721 IC50 300.0 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens SMMC-7721 IC50 370.0 nM 10.1016/j.bmc.2015.04.071
Homo sapiens SMMC-7721 IC50 2370.0 nM 10.1021/acs.jmedchem.2c00520
Homo sapiens SMMC-7721 IC50 4880.0 nM 10.1016/j.ejmech.2022.114402
Homo sapiens SMMC-7721 IC50 6230.0 nM 10.1016/j.bmc.2012.05.051
Homo sapiens SMMC-7721 IC50 8800.0 nM 10.1021/acs.jnatprod.2c00908
Homo sapiens SMMC-7721 IC50 10000.0 nM 10.1021/acs.jnatprod.0c00396
Homo sapiens SMMC-7721 IC50 10610.0 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens SMMC-7721 IC50 17300.0 nM 10.1021/jm1014814
Homo sapiens SMMC-7721 IC50 18700.0 nM 10.1016/j.bmc.2013.11.013
Homo sapiens SMMC-7721 TGI 45.1 % 10.1016/j.ejmech.2021.113670
Homo sapiens SN12C GI50 2510.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens SN12C GI50 2510.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SN12C GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SN12C GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SN12C IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SN12C IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SN12C LC50 39800.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SN12C TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SN12C TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SN12C TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SN12C TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SN12C TGI 10000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SNB-19 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SNB-19 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SNB-19 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SNB-19 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SNB-19 TGI 3980.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SNB-19 TGI 3980.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SNB-19 TGI 3980.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SNB-19 TGI 3980.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SNB-75 GI50 3160.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens SNB-75 GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SNB-75 GI50 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SNB-75 IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SNB-75 IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SNB-75 IC50 3160.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens SNB-75 IC50 518090.53 nM 10.6019/CHEMBL1201861
Homo sapiens SNB-75 LC50 7940.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens SNB-75 TGI 3980.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SNB-75 TGI 3980.0 nM 10.1016/j.ejmech.2016.04.048
Homo sapiens SNB-75 TGI 3980.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SNB-75 TGI 3980.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SNB-75 TGI 3980.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SNF-related serine/threonine-protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens SNG-M Activity 0.155 None 10.1073/pnas.0707498104
Homo sapiens SNG-M Activity 0.16 None 10.1073/pnas.0707498104
Homo sapiens SNG-M Activity 0.94 None 10.1073/pnas.0707498104
Homo sapiens SNU1 IC50 2316.2 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-16 Activity 0.458 None 10.1073/pnas.0707498104
Homo sapiens SNU-16 IC50 9210.26 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-387 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens SNU-387 IC50 8290.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens SNU-387 IC50 12330.0 nM 10.1016/j.ejmech.2022.114402
Homo sapiens SNU-387 IC50 258910.0 nM 10.1021/acs.jmedchem.0c02026
Homo sapiens SNU-398 Activity 0.094 None 10.1073/pnas.0707498104
Homo sapiens SNU-398 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens SNU-398 IC50 3380.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens SNU-449 Activity 0.09 None 10.1073/pnas.0707498104
Homo sapiens SNU-449 Activity 0.094 None 10.1073/pnas.0707498104
Homo sapiens SNU-449 Activity 0.99 None 10.1073/pnas.0707498104
Homo sapiens SNU-5 IC50 267382.98 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-C1 IC50 455703.78 nM 10.6019/CHEMBL1201861
Homo sapiens SPS1/STE20-related protein kinase YSK4 Kd 99.0 nM 10.1038/nbt.1990
Homo sapiens SPS1/STE20-related protein kinase YSK4 Kd 99.0 nM 10.1182/blood-2009-05-222034
Homo sapiens SR GI50 3160.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens SR GI50 3160.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SR GI50 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SR IC50 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SR IC50 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SR IC50 6006.78 nM 10.6019/CHEMBL1201861
Homo sapiens SR LC50 100000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens SR TGI 63100.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SR TGI 63100.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SR TGI 63100.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SR TGI 100000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens ST486 IC50 3836.73 nM 10.6019/CHEMBL1201861
Homo sapiens STE20-related kinase adapter protein alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens STE20/SPS1-related proline-alanine-rich protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens STE20/SPS1-related proline-alanine-rich protein kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Activity -63.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Stem cell growth factor receptor IC50 10.0 nM 10.1021/jm801050k
Homo sapiens Stem cell growth factor receptor IC50 31.0 nM 10.1021/jm300338m
Homo sapiens Stem cell growth factor receptor IC50 68.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Stem cell growth factor receptor IC50 68.0 nM 10.1021/acs.jmedchem.1c00678
Homo sapiens Stem cell growth factor receptor IC50 68.0 nM 10.1021/jm901132v
Homo sapiens Stem cell growth factor receptor IC50 68.0 nM 10.1038/nchembio799
Homo sapiens Stem cell growth factor receptor IC50 80.0 nM 10.1016/j.ejmech.2019.06.063
Homo sapiens Stem cell growth factor receptor IC50 1625.0 nM 10.1016/j.ejmech.2020.113081
Homo sapiens Stem cell growth factor receptor IC50 nan None 10.1016/j.bmc.2010.05.021
Homo sapiens Stem cell growth factor receptor IC50 nan None 10.1016/j.ejmech.2014.07.099
Homo sapiens Stem cell growth factor receptor Inhibition 65.81 % 10.1016/j.ejmech.2020.113081
Homo sapiens Stem cell growth factor receptor Inhibition 95.6 % 10.1016/j.ejmech.2016.02.071
Homo sapiens Stem cell growth factor receptor Kd 11.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 16.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 16.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 16.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 18.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 18.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 18.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 20.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 25.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 28.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 31.0 nM 10.1016/j.ejmech.2011.02.057
Homo sapiens Stem cell growth factor receptor Kd 31.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 31.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 240.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 240.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 240.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 310.0 nM 10.1016/j.ejmech.2011.02.057
Homo sapiens Stem cell growth factor receptor Kd 310.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 310.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 310.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 430.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 740.0 nM 10.1038/nbt1068
Homo sapiens Stem cell growth factor receptor Kd 740.0 nM 10.1073/pnas.0707498104
Homo sapiens Stem cell growth factor receptor Ki 3981.07 nM None
Homo sapiens Structural maintenance of chromosomes protein 1A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Structural maintenance of chromosomes protein 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens SU-DHL-1 IC50 63599.72 nM 10.6019/CHEMBL1201861
Homo sapiens SU-DHL-6 IC50 1.0 nM 10.1016/j.ejmech.2020.112679
Homo sapiens SU-DHL-6 IC50 3820.0 nM 10.1021/acs.jmedchem.7b01465
Homo sapiens SUP-T1 IC50 914674.26 nM 10.6019/CHEMBL1201861
Homo sapiens SW1088 Activity 1.147 None 10.1073/pnas.0707498104
Homo sapiens SW13 Activity 1.208 None 10.1073/pnas.0707498104
Homo sapiens SW1417 Activity 1.061 None 10.1073/pnas.0707498104
Homo sapiens SW1463 Activity 0.931 None 10.1073/pnas.0707498104
Homo sapiens SW1573 Activity 0.899 None 10.1073/pnas.0707498104
Homo sapiens SW1710 Activity 0.448 None 10.1073/pnas.0707498104
Homo sapiens SW1783 Activity 1.151 None 10.1073/pnas.0707498104
Homo sapiens SW1990 Activity 1.204 None 10.1073/pnas.0707498104
Homo sapiens SW48 Activity 0.898 None 10.1073/pnas.0707498104
Homo sapiens SW480 GI 28.1 % 10.1016/j.ejmech.2014.11.008
Homo sapiens SW480 GI50 14700.0 nM 10.1021/acs.jmedchem.2c01042
Homo sapiens SW480 GI50 15600.0 nM 10.1021/acs.jmedchem.2c00820
Homo sapiens SW480 IC50 nan None 10.1016/j.ejmech.2014.11.008
Homo sapiens SW480 IC50 nan None 10.1016/j.ejmech.2022.114376
Homo sapiens SW480 Inhibition 83.8 % 10.1016/j.ejmech.2020.113006
Homo sapiens SW-620 Activity 0.971 None 10.1073/pnas.0707498104
Homo sapiens SW-620 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SW-620 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SW-620 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SW-620 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SW-620 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens SW-620 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens SW-620 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens SW-620 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens SW684 IC50 478338.19 nM 10.6019/CHEMBL1201861
Homo sapiens SW756 Activity 0.599 None 10.1073/pnas.0707498104
Homo sapiens SW780 Activity 0.509 None 10.1073/pnas.0707498104
Homo sapiens SW837 Activity 0.858 None 10.1073/pnas.0707498104
Homo sapiens SW872 IC50 204932.57 nM 10.6019/CHEMBL1201861
Homo sapiens SW900 Activity 0.86 None 10.1073/pnas.0707498104
Homo sapiens SW948 Activity 0.933 None 10.1073/pnas.0707498104
Homo sapiens SW 954 IC50 6458.66 nM 10.6019/CHEMBL1201861
Homo sapiens SW 962 IC50 68212.03 nM 10.6019/CHEMBL1201861
Homo sapiens T-24 Activity 0.889 None 10.1073/pnas.0707498104
Homo sapiens T-24 Activity 4.45 % 10.1016/j.ejmech.2020.112661
Homo sapiens T-24 Activity 4.88 % 10.1016/j.ejmech.2020.112661
Homo sapiens T-24 Activity 5.15 % 10.1016/j.ejmech.2020.112661
Homo sapiens T-24 Activity 7.31 % 10.1016/j.ejmech.2020.112661
Homo sapiens T-24 Activity 7.85 % 10.1016/j.ejmech.2020.112661
Homo sapiens T-24 Activity 16.2 % 10.1016/j.ejmech.2020.112661
Homo sapiens T-24 Activity 541.9 pg 10.1016/j.ejmech.2020.112661
Homo sapiens T-24 Activity nan None 10.1016/j.ejmech.2020.112661
Homo sapiens T-24 IC50 5310.0 nM 10.1016/j.ejmech.2020.112661
Homo sapiens T47D Activity 0.777 None 10.1073/pnas.0707498104
Homo sapiens T47D GI50 1580.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens T47D GI50 1580.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens T47D GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens T47D GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens T47D IC50 610.0 nM 10.1016/j.ejmech.2015.03.008
Homo sapiens T47D IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens T47D IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens T47D IC50 1600.0 nM 10.1016/j.ejmech.2019.06.063
Homo sapiens T47D IC50 6400.0 nM 10.1016/j.ejmech.2020.112942
Homo sapiens T47D LC50 31600.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens T47D TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens T47D TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens T47D TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens T47D TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens T47D TGI 7940.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens T47D TGI 14380.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens T84 Activity 0.958 None 10.1073/pnas.0707498104
Homo sapiens T98G Activity 0.488 None 10.1073/pnas.0707498104
Homo sapiens TALL-1 IC50 151556.58 nM 10.6019/CHEMBL1201861
Homo sapiens Tankyrase-2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens TCO-1 Activity 0.642 None 10.1073/pnas.0707498104
Homo sapiens TE-1 IC50 158055.94 nM 10.6019/CHEMBL1201861
Homo sapiens TE-10 IC50 8763.53 nM 10.6019/CHEMBL1201861
Homo sapiens TE-12 IC50 5249.29 nM 10.6019/CHEMBL1201861
Homo sapiens TE-15 IC50 382903.12 nM 10.6019/CHEMBL1201861
Homo sapiens TE-441-T IC50 467129.72 nM 10.6019/CHEMBL1201861
Homo sapiens TE-5 IC50 3131.62 nM 10.6019/CHEMBL1201861
Homo sapiens TE-6 IC50 126404.11 nM 10.6019/CHEMBL1201861
Homo sapiens TE-8 IC50 21639.36 nM 10.6019/CHEMBL1201861
Homo sapiens TE-9 IC50 21851.33 nM 10.6019/CHEMBL1201861
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Ki 1584.89 nM None
Homo sapiens Testis-specific serine/threonine-protein kinase 2 Ki 1584.89 nM None
Homo sapiens TGBC1TKB IC50 26982.81 nM 10.6019/CHEMBL1201861
Homo sapiens TGF-beta receptor type I Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens TGF-beta receptor type I Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens TGF-beta receptor type I Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens TGF-beta receptor type I Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TGF-beta receptor type II Kd 6900.0 nM 10.1038/nbt.1990
Homo sapiens TGF-beta receptor type II Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens TGF-beta receptor type II Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens TGF-beta receptor type II Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TGW Activity 0.22 None 10.1073/pnas.0707498104
Homo sapiens TGW Activity 0.224 None 10.1073/pnas.0707498104
Homo sapiens TGW Activity 1.07 None 10.1073/pnas.0707498104
Homo sapiens TGW IC50 49079.09 nM 10.6019/CHEMBL1201861
Homo sapiens THP-1 IC50 310.0 nM 10.1016/j.bmc.2010.05.021
Homo sapiens THP-1 IC50 27214.09 nM 10.6019/CHEMBL1201861
Homo sapiens THP-1 IC50 nan None 10.1016/j.bmc.2018.05.004
Homo sapiens Thromboxane A2 receptor AC50 16346.3 nM 10.1038/s41467-023-40064-9
Homo sapiens Thyroid hormone receptor-associated protein 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TK-10 GI50 3980.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens TK-10 GI50 3980.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens TK-10 IC50 3980.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens TK-10 IC50 3980.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens TK-10 IC50 232329.36 nM 10.6019/CHEMBL1201861
Homo sapiens TK-10 TGI 10000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens TK-10 TGI 10000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens TK-10 TGI 10000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens TK-10 TGI 10000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens TP53-regulating kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TPC1 EC50 2600.0 nM 10.1021/jm3003944
Homo sapiens TRAF2- and NCK-interacting kinase Kd 7900.0 nM 10.1038/nbt.1990
Homo sapiens TRAF2- and NCK-interacting kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens TRAF2- and NCK-interacting kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens TRAF2- and NCK-interacting kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TRAF2- and NCK-interacting kinase Kd nan None 10.1038/nbt1068
Homo sapiens Transient receptor potential cation channel subfamily M member 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens TT IC50 1.4 nM 10.1038/nchembio.117
Homo sapiens TUR IC50 1278288.05 nM 10.6019/CHEMBL1201861
Homo sapiens TYK-nu Activity 0.906 None 10.1073/pnas.0707498104
Homo sapiens Type-1 angiotensin II receptor AC50 10999.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine kinase non-receptor protein 2 Ki 3981.07 nM None
Homo sapiens Tyrosine-protein kinase ABL Activity -97.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Tyrosine-protein kinase ABL IC50 80.0 nM 10.1021/jm801050k
Homo sapiens Tyrosine-protein kinase ABL IC50 120.0 nM 10.1038/nchembio.117
Homo sapiens Tyrosine-protein kinase ABL Kd 130.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 130.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 130.0 nM 10.1039/C5MD00462D
Homo sapiens Tyrosine-protein kinase ABL Kd 130.0 nM 10.1073/pnas.0707498104
Homo sapiens Tyrosine-protein kinase ABL Kd 160.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 160.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 170.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 230.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 250.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 250.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 360.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 420.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 420.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 450.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 480.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 480.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 520.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 580.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 590.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 620.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 660.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 680.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 680.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 770.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 1200.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 1200.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 1400.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 1500.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 1600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 1700.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 2400.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 3400.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 3900.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 3900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 4400.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 4900.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 5500.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 7100.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase ABL Ki 158.49 nM None
Homo sapiens Tyrosine-protein kinase ABL2 Kd 1300.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL2 Kd 2900.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL2 Kd 2900.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL2 Kd 2900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase BLK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BLK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BLK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase BLK Ki 794.33 nM None
Homo sapiens Tyrosine-protein kinase BMX Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BMX Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BMX Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase BMX Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase BRK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BRK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BRK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase BRK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase BRK Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase BTK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BTK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BTK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase BTK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase BTK Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase BTK Ki 6309.57 nM None
Homo sapiens Tyrosine-protein kinase CSK Activity 63.0 % 10.1042/bj20070797
Homo sapiens Tyrosine-protein kinase CSK Kd 2900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase CSK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase CSK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase CSK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase CSK Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase CTK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase CTK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FER Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FER Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FER Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FER Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FER Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase FES Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FES Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FES Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FES Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FGR Kd 7800.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FGR Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FGR Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FGR Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase FRK Kd 440.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase FRK Kd 440.0 nM 10.1073/pnas.0707498104
Homo sapiens Tyrosine-protein kinase FRK Kd 440.0 nM None
Homo sapiens Tyrosine-protein kinase FRK Kd 510.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FRK Kd 510.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FRK Kd 510.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FRK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FYN Kd 8400.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FYN Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FYN Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FYN Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FYN Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase FYN Ki 3162.28 nM None
Homo sapiens Tyrosine-protein kinase HCK IC50 530.0 nM 10.1038/nchembio.117
Homo sapiens Tyrosine-protein kinase HCK Kd 8500.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase HCK Kd 8500.0 nM 10.1039/C5MD00462D
Homo sapiens Tyrosine-protein kinase HCK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase HCK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase HCK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase HCK Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase HCK Ki 3162.28 nM None
Homo sapiens Tyrosine-protein kinase ITK/TSK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ITK/TSK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ITK/TSK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ITK/TSK Ki 1584.89 nM None
Homo sapiens Tyrosine-protein kinase JAK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase JAK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase JAK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase JAK1 Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase JAK2 Activity -94.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Tyrosine-protein kinase JAK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase JAK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase JAK2 Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase JAK2 Ki 2511.89 nM None
Homo sapiens Tyrosine-protein kinase JAK3 Kd 7300.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase JAK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase JAK3 Ki 5011.87 nM None
Homo sapiens Tyrosine-protein kinase LCK IC50 60.0 nM 10.1021/jm801050k
Homo sapiens Tyrosine-protein kinase LCK Kd 2700.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase LCK Kd 2700.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase LCK Kd 2700.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase LCK Kd 6900.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase LCK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase LCK Ki 1995.26 nM None
Homo sapiens Tyrosine-protein kinase Lyn Kd 3000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase Lyn Kd 3000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase Lyn Kd 3000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase Lyn Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase Lyn Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase Lyn Ki 398.11 nM None
Homo sapiens Tyrosine-protein kinase receptor FLT3 GI50 43.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Tyrosine-protein kinase receptor FLT3 GI50 56.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Tyrosine-protein kinase receptor FLT3 GI50 9300.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 1.3 nM 10.1016/j.ejmech.2019.05.021
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 2.0 nM 10.1021/jm500118j
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 2.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 2.8 nM 10.1016/j.bmc.2021.116596
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 3.2 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 4.0 nM 10.1021/jm500118j
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 7.0 nM 10.1021/jm301537p
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 15.48 nM 10.1021/acs.jmedchem.7b01261
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 20.0 nM 10.1021/acs.jmedchem.0c00696
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 32.6 nM 10.1016/j.bmc.2021.116596
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 33.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 33.0 nM 10.1021/jm301537p
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 44.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 48.6 nM 10.1016/j.bmc.2021.116596
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 54.0 nM 10.1016/j.bmc.2011.06.016
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 54.0 nM 10.1016/j.bmc.2013.03.083
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 54.0 nM 10.1016/j.bmcl.2012.05.116
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 58.0 nM 10.1016/j.ejmech.2020.112205
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 58.0 nM 10.1016/j.ejmech.2020.113043
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 58.0 nM 10.1021/acs.jmedchem.0c00696
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 58.0 nM 10.1021/acs.jmedchem.7b00901
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 58.0 nM 10.1038/nchembio799
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 62.0 nM 10.1016/j.ejmech.2021.113776
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 103.5 nM 10.1016/j.bmc.2021.116596
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 nan None 10.1016/j.bmc.2010.05.021
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 nan None 10.1016/j.bmc.2017.09.003
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 nan None 10.1016/j.ejmech.2014.07.099
Homo sapiens Tyrosine-protein kinase receptor FLT3 Inhibition 98.5 % 10.1016/j.ejmech.2016.02.071
Homo sapiens Tyrosine-protein kinase receptor FLT3 Inhibition nan % 10.1021/acs.jmedchem.5b01582
Homo sapiens Tyrosine-protein kinase receptor FLT3 Inhibition nan % 10.1021/acs.jmedchem.7b01261
Homo sapiens Tyrosine-protein kinase receptor FLT3 Inhibition nan % 10.1021/acsmedchemlett.2c00402
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 4.5 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 4.5 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1021/acs.jmedchem.8b01714
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 13.0 nM 10.1021/acs.jmedchem.8b01714
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 13.0 nM 10.1021/jm9007533
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 13.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 13.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 13.0 nM 10.1039/C5MD00462D
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 13.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 17.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 20.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 20.0 nM 10.1073/pnas.0707498104
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 30.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 30.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 30.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 79.0 nM 10.1021/jm301537p
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 79.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 79.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 82.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 82.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 82.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 95.0 nM 10.1021/acs.jmedchem.8b01714
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 630.0 nM 10.1021/acs.jmedchem.8b01714
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 860.0 nM 10.1021/acs.jmedchem.8b01714
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 1759.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase receptor FLT3 Ki 794.33 nM None
Homo sapiens Tyrosine-protein kinase receptor RET GI50 47.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Tyrosine-protein kinase receptor RET GI50 110.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Tyrosine-protein kinase receptor RET GI50 147.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Tyrosine-protein kinase receptor RET IC50 5.9 nM 10.1016/j.ejmech.2022.114226
Homo sapiens Tyrosine-protein kinase receptor RET IC50 5.9 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Tyrosine-protein kinase receptor RET IC50 6.0 nM 10.1021/jm501464c
Homo sapiens Tyrosine-protein kinase receptor RET IC50 9.0 nM 10.1016/j.ejmech.2017.09.018
Homo sapiens Tyrosine-protein kinase receptor RET IC50 9.0 nM 10.1038/nchembio.117
Homo sapiens Tyrosine-protein kinase receptor RET IC50 11.0 nM 10.1016/j.ejmech.2017.09.018
Homo sapiens Tyrosine-protein kinase receptor RET IC50 152.3 nM 10.1021/acs.jmedchem.1c01280
Homo sapiens Tyrosine-protein kinase receptor RET Inhibition 97.0 % 10.1016/j.ejmech.2016.02.071
Homo sapiens Tyrosine-protein kinase receptor RET Inhibition nan % 10.1038/nchembio.117
Homo sapiens Tyrosine-protein kinase receptor RET Kd 7.4 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor RET Kd 7.4 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 7.4 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor RET Kd 13.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor RET Kd 13.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 13.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor RET Kd 22.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 22.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor RET Kd 39.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 39.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor RET Kd 62.0 nM 10.1016/j.ejmech.2020.112421
Homo sapiens Tyrosine-protein kinase receptor RET Kd 117.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase receptor RET Ki 100.0 nM None
Homo sapiens Tyrosine-protein kinase receptor Tie-1 Kd 68.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor Tie-1 Kd 68.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor Tie-1 Kd 68.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Ki 3162.28 nM None
Homo sapiens Tyrosine-protein kinase receptor UFO Kd 4500.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor UFO Kd 4500.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor UFO Kd 4500.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor UFO Ki 158.49 nM None
Homo sapiens Tyrosine-protein kinase SRC Activity 22.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Tyrosine-protein kinase SRC IC50 390.0 nM 10.1038/nchembio.117
Homo sapiens Tyrosine-protein kinase SRC Inhibition nan % 10.1021/acs.jmedchem.5b01582
Homo sapiens Tyrosine-protein kinase SRC Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase SRC Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase SRC Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase SRC Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase SRC Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase SRC Kd nan None 10.1039/C5MD00462D
Homo sapiens Tyrosine-protein kinase SRC Ki 1995.26 nM None
Homo sapiens Tyrosine-protein kinase Srms Kd 9800.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase Srms Kd 9800.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase Srms Kd 9800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase SYK Activity 15.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Tyrosine-protein kinase SYK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase SYK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase SYK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase SYK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase SYK Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase TEC Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TEC Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TEC Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase TEC Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase TIE-2 IC50 0.39 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens Tyrosine-protein kinase TIE-2 IC50 0.39 nM 10.1016/j.ejmech.2018.12.067
Homo sapiens Tyrosine-protein kinase TIE-2 IC50 0.83 nM 10.1016/j.ejmech.2016.12.059
Homo sapiens Tyrosine-protein kinase TIE-2 IC50 6.77 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens Tyrosine-protein kinase TIE-2 IC50 7.85 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens Tyrosine-protein kinase TIE-2 IC50 nan None 10.1016/j.ejmech.2019.06.063
Homo sapiens Tyrosine-protein kinase TIE-2 Kd 2100.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TIE-2 Kd 2100.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TIE-2 Kd 2100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase TIE-2 Kd 3000.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase TXK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TXK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TXK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase TYK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TYK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TYK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase TYK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase TYK2 Ki 1995.26 nM None
Homo sapiens Tyrosine-protein kinase YES Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase YES Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase YES Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase YES Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase YES Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase YES Potency 27403.8 nM None
Homo sapiens Tyrosine-protein kinase YES Potency 34499.3 nM None
Homo sapiens Tyrosine-protein kinase ZAP-70 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ZAP-70 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ZAP-70 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 3162.3 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 5623.4 nM None
Homo sapiens Tyrosyl-tRNA synthetase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens U-251 GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens U-251 GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens U-251 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens U-251 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens U-251 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens U-251 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens U-251 IC50 2000.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens U-251 IC50 24710.0 nM 10.1016/j.bmc.2010.03.077
Homo sapiens U-251 LC50 25100.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens U-251 TGI 3160.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens U-251 TGI 3160.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens U-251 TGI 3160.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens U-251 TGI 3160.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens U-251 TGI 6310.0 nM 10.1016/j.ejmech.2016.02.039
Homo sapiens U-266 IC50 156470.27 nM 10.6019/CHEMBL1201861
Homo sapiens U373 MG Activity 1.065 None 10.1073/pnas.0707498104
Homo sapiens U5 small nuclear ribonucleoprotein 200 kDa helicase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens U-698-M IC50 22460.34 nM 10.6019/CHEMBL1201861
Homo sapiens U-87 MG IC50 8460.0 nM 10.1016/j.ejmech.2022.114376
Homo sapiens U-87 MG IC50 540109.02 nM 10.6019/CHEMBL1201861
Homo sapiens U-937 Activity 8.76 % 10.1021/jm500118j
Homo sapiens U-937 GI50 2340.0 nM 10.1016/j.bmc.2018.02.009
Homo sapiens U-937 GI50 2740.0 nM 10.1016/j.ejmech.2015.08.031
Homo sapiens U-937 GI50 2850.0 nM 10.1016/j.bmc.2011.09.042
Homo sapiens U-937 GI50 3400.0 nM 10.1016/j.bmc.2011.06.016
Homo sapiens U-937 GI50 3400.0 nM 10.1016/j.bmc.2013.03.083
Homo sapiens U-937 GI50 3400.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens U-937 IC50 3000.0 nM 10.1021/jm500118j
Homo sapiens U-937 IC50 5000.0 nM 10.1016/j.bmc.2010.05.021
Homo sapiens UACC-257 GI50 2000.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens UACC-257 GI50 2000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens UACC-257 IC50 2000.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens UACC-257 IC50 2000.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens UACC-257 IC50 13512.55 nM 10.6019/CHEMBL1201861
Homo sapiens UACC-257 TGI 5010.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens UACC-257 TGI 5010.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens UACC-257 TGI 5010.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens UACC-257 TGI 5010.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens UACC-62 GI50 1580.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens UACC-62 GI50 1580.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens UACC-62 IC50 1580.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens UACC-62 IC50 1580.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens UACC-62 IC50 1950.0 nM 10.1016/j.bmc.2020.115897
Homo sapiens UACC-62 TGI 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens UACC-62 TGI 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens UACC-62 TGI 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens UACC-62 TGI 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens UACC-812 Activity 1.118 None 10.1073/pnas.0707498104
Homo sapiens UACC-812 IC50 216101.89 nM 10.6019/CHEMBL1201861
Homo sapiens Ubiquitin carboxyl-terminal hydrolase 1 Potency 14125.4 nM None
Homo sapiens UMC-11 Activity 0.925 None 10.1073/pnas.0707498104
Homo sapiens UMUC3 Activity 0.747 None 10.1073/pnas.0707498104
Homo sapiens Uncharacterized aarF domain-containing protein kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Uncharacterized aarF domain-containing protein kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Uncharacterized aarF domain-containing protein kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Uncharacterized aarF domain-containing protein kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Uncharacterized protein FLJ45252 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens UO-31 Activity 0.908 None 10.1073/pnas.0707498104
Homo sapiens UO-31 GI50 2510.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens UO-31 GI50 2510.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens UO-31 IC50 2510.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens UO-31 IC50 2510.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens UO-31 IC50 2510.0 nM 10.1016/j.ejmech.2018.09.005
Homo sapiens UO-31 IC50 2510.0 nM 10.1016/j.ejmech.2021.113674
Homo sapiens UO-31 TGI 6310.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens UO-31 TGI 6310.0 nM 10.1016/j.ejmech.2017.01.006
Homo sapiens UO-31 TGI 6310.0 nM 10.1016/j.ejmech.2018.07.008
Homo sapiens UO-31 TGI 6310.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens VA-ES-BJ IC50 69686.11 nM 10.6019/CHEMBL1201861
Homo sapiens Vascular endothelial growth factor receptor IC50 nan None 10.1016/j.ejmech.2014.07.099
Homo sapiens Vascular endothelial growth factor receptor 1 Activity -78.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 18.0 nM 10.1016/j.bmc.2011.06.016
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 26.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 31.0 nM 10.1021/jm300338m
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 165.0 nM 10.1016/j.bmcl.2012.05.116
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 402.0 nM 10.1021/acs.jmedchem.5b01582
Homo sapiens Vascular endothelial growth factor receptor 1 Kd 31.0 nM 10.1016/j.ejmech.2020.112421
Homo sapiens Vascular endothelial growth factor receptor 1 Kd 31.0 nM 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 1 Kd 31.0 nM 10.1038/nbt.1990
Homo sapiens Vascular endothelial growth factor receptor 1 Kd 31.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Vascular endothelial growth factor receptor 1 Ki 316.23 nM None
Homo sapiens Vascular endothelial growth factor receptor 2 AC50 25.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vascular endothelial growth factor receptor 2 Activity -75.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 47.0 % 10.1016/j.ejmech.2018.11.023
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 49.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 50.0 % 10.1016/j.ejmech.2018.11.023
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 50.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 65.0 % 10.1016/j.ejmech.2018.11.023
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 77.0 % 10.1016/j.ejmech.2018.11.023
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 77.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 80.0 % 10.1016/j.ejmech.2018.11.023
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 80.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 84.0 % 10.1016/j.ejmech.2019.03.012
Homo sapiens Vascular endothelial growth factor receptor 2 Activity 90.0 % 10.1016/j.ejmech.2018.11.023
Homo sapiens Vascular endothelial growth factor receptor 2 deltaTm nan None 10.1016/j.ejmech.2019.03.012
Homo sapiens Vascular endothelial growth factor receptor 2 EC50 500.0 nM 10.1073/pnas.0707498104
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.06 nM 10.1016/j.ejmech.2020.112946
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.16 nM 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.17 nM 10.1016/j.ejmech.2018.11.042
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.17 nM 10.1016/j.ejmech.2018.12.067
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.17 nM 10.1016/j.ejmech.2021.113768
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.45 nM 10.1016/j.ejmech.2016.12.059
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.48 nM 10.1016/j.bmc.2015.04.071
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.48 nM 10.1016/j.ejmech.2015.08.045
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.588 ug.mL-1 10.1016/j.bmc.2020.115872
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.85 nM 10.1016/j.bmc.2015.01.006
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 0.85 nM 10.1016/j.ejmech.2017.10.030
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 1.06 nM 10.1016/j.bmc.2013.11.027
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 1.06 nM 10.1039/C3MD00192J
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 1.2 nM 10.1016/j.bmc.2015.12.001
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 1.27 nM 10.1016/j.ejmech.2017.10.008
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 1.42 nM 10.1016/j.bmc.2015.12.038
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 3.0 nM 10.1016/j.bmc.2011.06.016
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 3.12 nM 10.1016/j.bmc.2021.116384
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 3.2 nM 10.1016/j.ejmech.2021.114085
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 6.2 nM 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 7.8 nM 10.1021/acs.jmedchem.5b01582
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 8.0 nM 10.1021/acs.jmedchem.5b01582
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 10.0 nM 10.1016/j.ejmech.2015.12.032
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 11.1 nM None
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 15.0 nM 10.1016/j.bmc.2018.12.032
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 15.0 nM 10.1016/j.ejmech.2020.113043
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 17.6 nM 10.1016/j.ejmech.2018.05.054
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 19.0 nM 10.1016/j.ejmech.2019.111587
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 20.0 nM 10.1016/j.bmc.2013.03.083
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 20.0 nM 10.1016/j.bmcl.2012.05.116
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 21.0 nM 10.1016/j.bmcl.2021.127788
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 23.0 nM 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 25.7 nM 10.1016/j.bmcl.2019.126711
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 27.0 nM 10.1038/nchembio.117
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 28.0 nM 10.1016/j.ejmech.2021.113192
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 30.0 nM 10.1016/j.bmcl.2018.03.089
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 37.8 nM 10.1016/j.ejmech.2019.06.054
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 42.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 46.41 nM 10.1021/acs.jmedchem.7b01091
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 51.41 nM 10.1016/j.bmc.2021.116168
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 52.0 nM 10.1039/C3MD00096F
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 57.0 nM 10.1016/j.ejmech.2021.113867
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 59.0 nM 10.1021/jm300338m
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 68.0 nM 10.1016/j.bmc.2018.03.039
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 72.0 nM 10.1016/j.ejmech.2015.12.016
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 80.0 nM 10.1016/j.bmc.2020.115674
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1016/j.bmc.2015.08.010
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1016/j.bmcl.2013.03.042
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1016/j.ejmech.2010.09.002
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1016/j.ejmech.2014.11.008
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1016/j.ejmech.2015.02.019
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1016/j.ejmech.2016.02.029
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1016/j.ejmech.2018.11.061
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1021/acs.jmedchem.1c00678
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1021/acs.jmedchem.1c00700
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1021/acs.jmedchem.7b00901
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1021/acs.jmedchem.7b01091
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1021/jm301537p
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1021/jm901132v
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1038/nchembio799
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 90.0 nM 10.1039/d2md00065b
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 92.0 nM 10.1016/j.ejmech.2020.113081
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 100.0 nM 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 100.0 nM 10.1016/j.ejmech.2015.05.040
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 100.0 nM 10.1016/j.ejmech.2015.10.053
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 100.0 nM 10.1016/j.ejmech.2017.04.068
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 100.0 nM 10.1016/j.ejmech.2019.06.063
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 100.0 nM 10.1021/jm400045y
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 104.01 nM 10.1016/j.ejmech.2018.10.068
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 105.0 nM 10.1016/j.ejmech.2020.112062
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 110.0 nM 10.1016/j.ejmech.2018.11.061
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 113.0 nM 10.1016/j.bmc.2021.116454
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 120.0 nM 10.1016/j.bmcl.2022.128529
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 140.6 nM 10.1016/j.bmc.2019.06.001
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 170.0 nM 10.1016/j.bmc.2016.09.021
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 170.0 nM 10.1016/j.bmc.2017.09.003
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 170.0 nM 10.1016/j.bmcl.2016.10.029
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 170.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 179.7 nM 10.1016/j.bmc.2010.05.021
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 180.0 nM 10.1016/j.ejmech.2019.02.050
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 320.0 nM 10.1016/j.ejmech.2018.07.004
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 420.0 nM 10.1016/j.ejmech.2017.10.075
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 950.0 nM 10.1039/C8MD00057C
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 1210.0 nM 10.1016/j.ejmech.2020.112457
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 3000.0 nM 10.1016/j.ejmech.2020.112640
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 nan None 10.1016/j.ejmech.2014.07.099
Homo sapiens Vascular endothelial growth factor receptor 2 INH 100.0 uM 10.1016/j.ejmech.2021.113192
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 68.5 % 10.1039/C3MD00192J
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 90.0 % 10.1016/j.bmc.2016.03.008
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 91.49 % 10.1016/j.ejmech.2018.07.004
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 92.3 % 10.1016/j.bmc.2020.115674
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 94.3 % 10.1016/j.ejmech.2018.05.054
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 96.75 % 10.1021/acs.jmedchem.7b01091
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 96.8 % 10.1016/j.ejmech.2016.02.071
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 99.56 % 10.1016/j.ejmech.2020.113081
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 103.6 % 10.1016/j.ejmech.2019.06.054
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition 104.2 % 10.1016/j.bmcl.2019.126711
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition nan % 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition nan % 10.1016/j.bmc.2015.08.010
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition nan % 10.1016/j.ejmech.2015.02.019
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition nan % 10.1016/j.ejmech.2019.06.054
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 33.0 nM 10.1021/ml500394m
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 59.0 nM 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 59.0 nM 10.1038/nbt.1990
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 59.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 93.0 nM 10.1038/nbt1068
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 93.0 nM 10.1073/pnas.0707498104
Homo sapiens Vascular endothelial growth factor receptor 2 Ki 0.021 nM 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 Ki 0.12 nM 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 Ki 22.0 nM 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 Ki 39.81 nM None
Homo sapiens Vascular endothelial growth factor receptor 2 Selectivity 0.0972 None 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 2 T1/2 0.02667 hr 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 T1/2 0.1333 hr 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 T1/2 0.3 hr 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 T1/2 4.833 hr 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 T1/2 30.0 hr 10.1016/j.bmc.2011.08.002
Homo sapiens Vascular endothelial growth factor receptor 2 TIME 1.067 hr 10.1021/ml500394m
Homo sapiens Vascular endothelial growth factor receptor 3 Activity -97.0 % 10.1021/acs.jmedchem.0c01647
Homo sapiens Vascular endothelial growth factor receptor 3 IC50 3.0 nM 10.1016/j.bmc.2010.05.021
Homo sapiens Vascular endothelial growth factor receptor 3 IC50 16.0 nM 10.1021/jm300338m
Homo sapiens Vascular endothelial growth factor receptor 3 IC50 20.0 nM 10.1021/acs.jmedchem.0c02167
Homo sapiens Vascular endothelial growth factor receptor 3 IC50 20.0 nM 10.1021/acs.jmedchem.1c00678
Homo sapiens Vascular endothelial growth factor receptor 3 IC50 36.5 nM 10.1016/j.ejmech.2020.113081
Homo sapiens Vascular endothelial growth factor receptor 3 IC50 90.0 nM 10.1016/j.ejmech.2020.113043
Homo sapiens Vascular endothelial growth factor receptor 3 IC50 245.0 nM 10.1021/acs.jmedchem.5b01582
Homo sapiens Vascular endothelial growth factor receptor 3 Inhibition 9934.0 % 10.1016/j.ejmech.2020.113081
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 16.0 nM 10.1038/nbt1068
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 16.0 nM 10.1073/pnas.0707498104
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 95.0 nM 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 95.0 nM 10.1038/nbt.1990
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 95.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Vascular endothelial growth factor receptor 3 Ki 100.0 nM None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Very long-chain specific acyl-CoA dehydrogenase, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens VM-CUB-1 Activity 0.496 None 10.1073/pnas.0707498104
Homo sapiens VMRC-LCP Activity 0.339 None 10.1073/pnas.0707498104
Homo sapiens VMRC-MELG Activity 0.915 None 10.1073/pnas.0707498104
Homo sapiens VMRC-RCZ Activity 1.134 None 10.1073/pnas.0707498104
Homo sapiens Wee1-like protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Wee1-like protein kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens WI-38 GI50 20000.0 nM 10.1016/j.ejmech.2022.114434
Homo sapiens WI-38 IC50 7540.0 nM 10.1016/j.ejmech.2014.04.059
Homo sapiens WI-38 IC50 10650.0 nM 10.1016/j.ejmech.2022.114661
Homo sapiens WI-38 IC50 14700.0 nM 10.1016/j.bmc.2022.116894
Homo sapiens WI-38 IC50 30000.0 nM 10.1016/j.ejmech.2020.113081
Homo sapiens WI-38 VA13 Activity 0.818 None 10.1073/pnas.0707498104
Homo sapiens WiDr Activity 0.9 None 10.1073/pnas.0707498104
Homo sapiens WSU-NHL IC50 36163.96 nM 10.6019/CHEMBL1201861
Homo sapiens YAPC Activity 0.831 None 10.1073/pnas.0707498104
Homo sapiens YKG-1 Activity 0.719 None 10.1073/pnas.0707498104
Homo sapiens YT IC50 59310.78 nM 10.6019/CHEMBL1201861
Homo sapiens ZR-75-1 Activity 1.35 None 10.1073/pnas.0707498104
Homo sapiens ZR-75-30 Activity 0.946 None 10.1073/pnas.0707498104
Homo sapiens ZR-75-30 IC50 2960.0 nM 10.1016/j.ejmech.2017.10.030
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 416.0 nM 10.1021/acs.jmedchem.0c01467
Lyssavirus rabies Lyssavirus rabies Activity 70.0 % 10.1021/acs.jmedchem.0c01467
Middle East respiratory syndrome-related coronavirus Middle East respiratory syndrome-related coronavirus Activity 30.0 % 10.1021/acs.jmedchem.0c01467
Middle East respiratory syndrome-related coronavirus Middle East respiratory syndrome-related coronavirus Activity 93.0 % 10.1021/acs.jmedchem.0c01467
Mus musculus B16-BL6 IC50 36480.0 nM 10.1016/j.bmc.2018.03.039
Mus musculus BaF3 GI50 2.8 nM 10.1021/acs.jmedchem.1c00459
Mus musculus BaF3 GI50 56.5 nM 10.1021/acs.jmedchem.1c00459
Mus musculus BaF3 GI50 206.2 nM 10.1021/acs.jmedchem.1c00459
Mus musculus BaF3 GI50 230.0 nM 10.1016/j.ejmech.2017.09.018
Mus musculus BaF3 GI50 1100.0 nM 10.1016/j.ejmech.2017.09.018
Mus musculus BaF3 GI50 1280.0 nM 10.1016/j.ejmech.2017.09.018
Mus musculus BaF3 GI50 1542.0 nM 10.1021/acs.jmedchem.1c00459
Mus musculus BaF3 GI50 1800.0 nM 10.1016/j.ejmech.2017.09.018
Mus musculus BaF3 GI50 2637.0 nM 10.1021/acs.jmedchem.1c00459
Mus musculus BaF3 GI50 5417.0 nM 10.1021/acs.jmedchem.1c00459
Mus musculus BaF3 GI50 6360.0 nM 10.1016/j.ejmech.2017.09.018
Mus musculus BaF3 IC50 6.0 nM 10.1016/j.ejmech.2019.05.021
Mus musculus BaF3 IC50 12.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 13.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 14.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 78.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 1015.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 1112.0 nM 10.1016/j.ejmech.2019.05.021
Mus musculus BaF3 IC50 1348.0 nM 10.1016/j.ejmech.2019.05.021
Mus musculus BaF3 IC50 1454.0 nM 10.1016/j.ejmech.2019.05.021
Mus musculus BaF3 IC50 2458.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 2804.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 3681.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 4208.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 5820.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 7400.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus BaF3 IC50 7997.0 nM 10.1016/j.ejmech.2019.05.021
Mus musculus BaF3 IC50 10000.0 nM 10.1021/acs.jmedchem.5b01582
Mus musculus CT26 GI50 14700.0 nM 10.1021/acs.jmedchem.2c00820
Mus musculus CT26 GI50 30200.0 nM 10.1021/acs.jmedchem.2c01042
Mus musculus CT26 IC50 2100.0 nM 10.1039/d2md00065b
Mus musculus H22 Inhibition 50.83 % 10.1021/acs.jmedchem.5b01807
Mus musculus H22 TGI 55.8 % 10.1016/j.bmc.2017.10.027
Mus musculus Mus musculus Activity 1.18 g 10.1016/j.ejmech.2014.10.039
Mus musculus Mus musculus Activity 26.4 g 10.1021/acs.jmedchem.5b01807
Mus musculus Mus musculus Activity nan None 10.1016/j.bmcl.2013.02.034
Mus musculus Mus musculus Activity nan None 10.1016/j.ejmech.2013.06.055
Mus musculus Mus musculus AUC 111559.2 ng.hr.mL-1 10.1182/blood-2009-05-222034
Mus musculus Mus musculus Cmax 12000.0 nM 10.1182/blood-2009-05-222034
Mus musculus Mus musculus Tmax 3.0 hr 10.1182/blood-2009-05-222034
Mus musculus NIH3T3 IC50 24750.0 nM 10.1016/j.bmcl.2012.05.004
Mus musculus NIH3T3 IC50 24750.0 nM 10.1016/j.ejmech.2011.04.031
Mus musculus Nuclear receptor ROR-gamma Potency 8912.5 nM None
Mus musculus Nuclear receptor ROR-gamma Potency 12589.3 nM None
Mus musculus Plasma PPB 99.0 % 10.1182/blood-2009-05-222034
Mus musculus Platelet-derived growth factor receptor beta IC50 100.0 nM 10.1021/jm400045y
Mus musculus Serine/threonine-protein kinase B-raf IC50 130.0 nM 10.1016/j.bmc.2018.03.038
Mus musculus Serine/threonine-protein kinase MST2 Kd nan None 10.1038/nbt1068
Mus musculus Tyrosine-protein kinase ABL IC50 225.9 nM 10.1016/j.bmc.2010.05.063
Mus musculus Tyrosine-protein kinase LCK Activity 27.0 % 10.1042/bj20070797
Mus musculus ULK3 kinase Kd nan None 10.1038/nbt1068
Mus musculus Vascular endothelial growth factor receptor 2 IC50 15.0 nM 10.1021/acs.jmedchem.7b00901
Mycobacterium tuberculosis Serine/threonine-protein kinase pknB Kd 10000.0 nM 10.1038/nbt.1990
Plasmodium falciparum Calcium-dependent protein kinase 1 Kd 220.0 nM 10.1038/nbt.1990
Plasmodium falciparum Plasmodium falciparum IC50 328.0 nM 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum IC50 376.0 nM 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum IC50 384.0 nM 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum IC50 509.0 nM 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum Inhibition 87.47 % 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum Potency 19011.5 nM None
Plasmodium falciparum (isolate 3D7) Cell division control protein 2 homolog Kd 10000.0 nM 10.1038/nbt.1990
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Aorta Inhibition nan % 10.1016/j.bmcl.2012.09.031
Rattus norvegicus C6 IC50 8170.0 nM 10.1016/j.ejmech.2022.114376
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Hepatocyte IC50 16550.0 nM 10.1016/j.bmc.2021.116384
Rattus norvegicus Liver IC50 18.39 nM 10.1002/hep.27206
Rattus norvegicus Liver microsomes Activity nan None 10.1016/j.bmcl.2008.04.002
Rattus norvegicus Peripheral myelin protein 22 Potency 12817.8 nM None
Rattus norvegicus Peripheral myelin protein 22 Potency 15836.9 nM None
Rattus norvegicus Thoracic aorta Inhibition nan % 10.1021/acs.jnatprod.8b00284
Rattus norvegicus Tubulin alpha-1 chain Kd 10000.0 nM 10.1038/nbt1358
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rift Valley fever virus Rift Valley fever virus EC50 3900.0 nM 10.1021/acs.jmedchem.0c01467
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 25.03 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.2484 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 4850.0 nM 10.1021/acs.jmedchem.1c00335
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.7 % 10.6019/CHEMBL4495565
Sindbis virus Sindbis virus EC50 1300.0 nM 10.1021/acs.jmedchem.0c01467
Staphylococcus aureus Staphylococcus aureus MIC 1.39 ug.mL-1 10.1016/j.ejmech.2022.114490
Staphylococcus aureus Staphylococcus aureus MIC 3000.0 nM 10.1016/j.ejmech.2022.114490
Staphylococcus aureus Staphylococcus aureus MIC 4300.0 nM 10.1016/j.bmcl.2022.128975
Staphylococcus aureus Staphylococcus aureus MIC 8610.0 nM 10.1016/j.bmcl.2022.128975
Staphylococcus aureus Staphylococcus aureus MIC 17200.0 nM 10.1016/j.bmcl.2022.128975
Staphylococcus epidermidis Staphylococcus epidermidis MIC 4300.0 nM 10.1016/j.bmcl.2022.128975
Staphylococcus epidermidis Staphylococcus epidermidis MIC 8610.0 nM 10.1016/j.bmcl.2022.128975
Trypanosoma brucei 6-phospho-1-fructokinase Potency 35481.3 nM None
Venezuelan equine encephalitis virus Venezuelan equine encephalitis virus EC50 3700.0 nM 10.1021/acs.jmedchem.0c01467
None ADMET Activity -10.3 % 10.1021/acs.jmedchem.7b01465
None ADMET Activity -5.2 % 10.1021/acs.jmedchem.7b01465
None ADMET Activity -2.4 % 10.1021/acs.jmedchem.7b01465
None ADMET Activity -2.0 % 10.1021/acs.jmedchem.7b01465
None ADMET Activity 0.224 None 10.1073/pnas.0707498104
None ADMET Activity 0.406 None 10.1073/pnas.0707498104
None ADMET Activity nan None 10.1016/j.bmc.2019.06.001
None ADMET Activity nan None 10.1016/j.bmc.2022.116757
None ADMET Activity nan None 10.1016/j.ejmech.2017.09.018
None ADMET Activity nan None 10.1016/j.ejmech.2019.05.021
None ADMET Activity nan None 10.1016/j.ejmech.2021.113670
None ADMET Activity nan None 10.1016/j.ejmech.2021.114010
None ADMET Activity nan None 10.1021/acs.jmedchem.1c00018
None ADMET Activity nan None 10.1021/acs.jmedchem.2c00520
None ADMET Activity nan None 10.1021/acs.jmedchem.9b00598
None ADMET AUC/dose 5.8 hr.Kg/L 10.1021/acs.jmedchem.1c00700
None ADMET CC50 7050.0 nM 10.1016/j.bmc.2016.05.055
None ADMET CLH nan None 10.1021/acs.jmedchem.7b01465
None ADMET FC 2.3 None 10.1021/acs.jmedchem.1c00175
None ADMET FC 4.3 None 10.1021/acs.jmedchem.1c00175
None ADMET IC50 8420.0 nM 10.1016/j.ejmech.2016.02.071
None ADMET IC50 15100.0 nM 10.1016/j.bmc.2009.12.020
None ADMET IC50 15100.0 nM 10.1016/j.bmcl.2007.05.059
None ADMET IC50 15100.0 nM 10.1016/j.bmcl.2008.04.073
None ADMET IC50 15800.0 nM 10.1016/j.ejmech.2013.06.055
None ADMET Inhibition 4.2 % 10.1016/j.bmc.2012.04.006
None ADMET Inhibition 5.3 % 10.1016/j.bmc.2012.04.006
None ADMET Inhibition 20.2 % 10.1016/j.bmc.2012.04.006
None ADMET Inhibition 23.2 % 10.1016/j.bmc.2012.04.006
None ADMET Papp 16.4 10^-6 cm/s 10.1016/j.ejmech.2022.114434
None ADMET permeability 110.0 nm/s 10.1021/acs.jmedchem.1c00700
None ADMET Ratio CC50/EC50 4.7 None 10.1016/j.bmc.2016.05.055
None ADMET Ratio IC50 2.0 None 10.1016/j.bmc.2022.116805
None ADMET Ratio IC50 2.2 None 10.1016/j.bmc.2022.117048
None ADMET Ratio IC50 3.0 None 10.1016/j.bmc.2009.12.020
None ADMET Survival 100.0 % 10.1021/acs.jmedchem.7b01465
None ADMET T1/2 5.6 hr 10.1016/j.ejmech.2018.11.033
None ADMET T1/2 6.8 hr 10.1021/acs.jmedchem.1c00700
None BC1 cell line IC50 3740.2 nM 10.6019/CHEMBL1201861
None COLO Activity 0.655 None 10.1073/pnas.0707498104
None COLO Activity 0.669 None 10.1073/pnas.0707498104
None COLO Activity 0.796 None 10.1073/pnas.0707498104
None COLO Activity 0.811 None 10.1073/pnas.0707498104
None COLO Activity 0.827 None 10.1073/pnas.0707498104
None COLO Activity 0.841 None 10.1073/pnas.0707498104
None COLO Activity 0.896 None 10.1073/pnas.0707498104
None COLO Activity 0.928 None 10.1073/pnas.0707498104
None COLO Activity 0.938 None 10.1073/pnas.0707498104
None COLO Activity 0.98 None 10.1073/pnas.0707498104
None COLO Activity 1.032 None 10.1073/pnas.0707498104
None COLO Activity 1.064 None 10.1073/pnas.0707498104
None COLO Activity 1.178 None 10.1073/pnas.0707498104
None COLO Activity 1.391 None 10.1073/pnas.0707498104
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 2.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Molecular identity unknown Activity nan None 10.1038/nchembio.117
None NON-PROTEIN TARGET Activity 0.01 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.011 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.026 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.029 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.03 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.035 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.04 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.055 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.06 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.084 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.087 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.09 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.136 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.14 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.196 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.2 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.22 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.24 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.243 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.25 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.268 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.27 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.319 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.323 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.355 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.368 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.381 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.389 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.401 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.408 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.414 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.419 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.426 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.43 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.433 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.434 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.451 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.462 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.47 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.483 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.486 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.494 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.5 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.51 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.517 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.518 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.541 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.544 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.55 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.561 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.562 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.574 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.581 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.598 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.607 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.614 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.615 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.632 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.646 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.648 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.65 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.656 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.658 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.661 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.665 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.666 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.667 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.668 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.672 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.677 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.687 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.718 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.719 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.72 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.724 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.725 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.732 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.736 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.737 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.743 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.75 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.756 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.758 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.759 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.762 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.763 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.764 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.767 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.77 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.772 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.773 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.786 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.788 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.789 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.79 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.791 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.793 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.794 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.796 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.801 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.802 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.819 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.82 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.822 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.827 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.829 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.83 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.832 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.836 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.837 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.838 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.839 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.85 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.852 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.854 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.86 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.861 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.862 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.869 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.874 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.876 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.878 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.88 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.885 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.889 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.891 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.892 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.893 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.894 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.896 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.897 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.9 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.904 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.911 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.913 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.916 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.917 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.92 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.924 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.926 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.928 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.929 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.931 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.933 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.937 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.941 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.946 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.947 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.949 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.95 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.953 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.957 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.959 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.962 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.965 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.967 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.97 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.971 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.973 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.974 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.976 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.978 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.979 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.98 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.981 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.982 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.983 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.987 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.992 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 0.995 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.0 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.004 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.006 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.01 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.011 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.012 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.023 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.024 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.029 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.033 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.04 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.043 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.047 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.05 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.051 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.07 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.082 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.085 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.088 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.095 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.103 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.117 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.126 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.13 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.135 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.15 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.155 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.162 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.194 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.223 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.24 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.255 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.29 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 1.297 None 10.1073/pnas.0707498104
None NON-PROTEIN TARGET Activity 36.0 % 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET Activity 44.0 % 10.1016/j.bmc.2016.01.008
None NON-PROTEIN TARGET Activity 47.9 % 10.1016/j.ejmech.2016.04.068
None NON-PROTEIN TARGET Activity 54.93 % 10.1016/j.ejmech.2016.04.068
None NON-PROTEIN TARGET Activity 62.0 % 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET Activity 66.0 % 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET Activity 97.11 mm3 10.1016/j.ejmech.2016.06.030
None NON-PROTEIN TARGET Activity 100.0 % 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET Activity 101.0 % 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET Activity 136.23 mm3 10.1016/j.ejmech.2016.06.030
None NON-PROTEIN TARGET Activity 193.0 % 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET Activity 206.94 mm3 10.1016/j.ejmech.2016.06.030
None NON-PROTEIN TARGET Activity 257.88 mm3 10.1016/j.ejmech.2016.06.030
None NON-PROTEIN TARGET Activity 334.93 mm3 10.1016/j.ejmech.2016.06.030
None NON-PROTEIN TARGET Activity 413.79 mm3 10.1016/j.ejmech.2016.06.030
None NON-PROTEIN TARGET Activity nan None 10.1016/j.ejmech.2015.08.031
None NON-PROTEIN TARGET Activity nan None 10.1021/jm900242c
None NON-PROTEIN TARGET EC50 1000.0 nM 10.1021/acs.jmedchem.6b00087
None NON-PROTEIN TARGET EC50 nan None 10.1021/acs.jmedchem.6b00087
None NON-PROTEIN TARGET FC 2.5 None 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET GI 48.41 % 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET GI 48.87 % 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET GI 70.0 % 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET GI 93.12 % 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET GI 97.32 % 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET GI50 650.0 nM 10.1016/j.bmcl.2010.04.039
None NON-PROTEIN TARGET GI50 780.0 nM 10.1016/j.bmcl.2010.01.064
None NON-PROTEIN TARGET GI50 780.0 nM 10.1016/j.bmcl.2016.01.037
None NON-PROTEIN TARGET GI50 1580.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET GI50 1580.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET GI50 2000.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET GI50 2000.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET GI50 2510.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET GI50 2510.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET GI50 2580.0 nM 10.1016/j.bmcl.2016.01.037
None NON-PROTEIN TARGET GI50 2740.0 nM 10.1016/j.bmcl.2014.05.030
None NON-PROTEIN TARGET GI50 3160.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET GI50 3160.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET GI50 3400.0 nM 10.1016/j.bmcl.2014.05.030
None NON-PROTEIN TARGET GI50 3980.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET GI50 4345.0 nM 10.1021/jm901509a
None NON-PROTEIN TARGET GI50 4500.0 nM 10.1021/jm900607f
None NON-PROTEIN TARGET GI50 4933.0 nM 10.1021/jm901509a
None NON-PROTEIN TARGET GI50 5580.0 nM 10.1016/j.bmc.2011.01.067
None NON-PROTEIN TARGET GI50 5580.0 nM 10.1016/j.bmc.2011.09.042
None NON-PROTEIN TARGET GI50 5580.0 nM 10.1016/j.bmcl.2010.01.064
None NON-PROTEIN TARGET GI50 5580.0 nM 10.1016/j.bmcl.2010.04.039
None NON-PROTEIN TARGET GI50 8100.0 nM 10.1016/j.bmcl.2012.09.004
None NON-PROTEIN TARGET GI50 8120.0 nM 10.1016/j.bmc.2012.04.047
None NON-PROTEIN TARGET GI50 8300.0 nM 10.1016/j.ejmech.2012.02.007
None NON-PROTEIN TARGET GI50 9300.0 nM 10.1016/j.bmc.2013.03.083
None NON-PROTEIN TARGET GI50 9400.0 nM 10.1016/j.bmc.2011.06.016
None NON-PROTEIN TARGET IC50 2.3 nM 10.1039/C1MD00175B
None NON-PROTEIN TARGET IC50 60.0 nM 10.1016/j.bmc.2014.11.029
None NON-PROTEIN TARGET IC50 650.0 nM 10.1016/j.ejmech.2015.08.045
None NON-PROTEIN TARGET IC50 870.0 nM 10.1016/j.ejmech.2015.03.008
None NON-PROTEIN TARGET IC50 900.0 nM 10.1016/j.bmcl.2015.07.082
None NON-PROTEIN TARGET IC50 1270.0 nM 10.1016/j.bmc.2013.04.004
None NON-PROTEIN TARGET IC50 1300.0 nM 10.1016/j.bmcl.2015.07.082
None NON-PROTEIN TARGET IC50 1580.0 nM 10.1016/j.bmc.2015.12.038
None NON-PROTEIN TARGET IC50 1900.0 nM 10.1016/j.ejmech.2013.06.060
None NON-PROTEIN TARGET IC50 1900.0 nM 10.1021/np5004577
None NON-PROTEIN TARGET IC50 2000.0 nM 10.1016/j.bmc.2016.01.049
None NON-PROTEIN TARGET IC50 2000.0 nM 10.1016/j.bmcl.2013.12.051
None NON-PROTEIN TARGET IC50 2190.0 nM 10.1016/j.ejmech.2014.04.059
None NON-PROTEIN TARGET IC50 2190.0 nM 10.1016/j.ejmech.2014.07.099
None NON-PROTEIN TARGET IC50 2190.0 nM 10.1016/j.ejmech.2014.10.022
None NON-PROTEIN TARGET IC50 2250.0 nM 10.1016/j.ejmech.2016.02.071
None NON-PROTEIN TARGET IC50 2320.0 nM 10.1016/j.ejmech.2014.04.059
None NON-PROTEIN TARGET IC50 2320.0 nM 10.1016/j.ejmech.2014.07.099
None NON-PROTEIN TARGET IC50 2320.0 nM 10.1016/j.ejmech.2014.10.022
None NON-PROTEIN TARGET IC50 2700.0 nM 10.1016/j.bmcl.2012.03.020
None NON-PROTEIN TARGET IC50 2920.0 nM 10.1016/j.bmcl.2016.10.029
None NON-PROTEIN TARGET IC50 3030.0 nM 10.1016/j.bmc.2016.09.021
None NON-PROTEIN TARGET IC50 3180.0 nM 10.1016/j.bmcl.2016.10.029
None NON-PROTEIN TARGET IC50 3200.0 nM 10.1016/j.bmc.2016.01.049
None NON-PROTEIN TARGET IC50 3200.0 nM 10.1016/j.bmcl.2013.12.051
None NON-PROTEIN TARGET IC50 3240.0 nM 10.1016/j.bmcl.2016.10.029
None NON-PROTEIN TARGET IC50 3440.0 nM 10.1016/j.bmcl.2016.10.029
None NON-PROTEIN TARGET IC50 4210.0 nM 10.1016/j.bmc.2016.09.021
None NON-PROTEIN TARGET IC50 4250.0 nM 10.1016/j.ejmech.2015.03.008
None NON-PROTEIN TARGET IC50 4900.0 nM 10.1016/j.bmc.2009.12.020
None NON-PROTEIN TARGET IC50 4900.0 nM 10.1016/j.bmcl.2007.05.059
None NON-PROTEIN TARGET IC50 4900.0 nM 10.1016/j.bmcl.2008.04.073
None NON-PROTEIN TARGET IC50 5000.0 nM 10.1016/j.bmc.2009.12.020
None NON-PROTEIN TARGET IC50 5000.0 nM 10.1016/j.bmc.2010.05.021
None NON-PROTEIN TARGET IC50 5000.0 nM 10.1021/jm801509w
None NON-PROTEIN TARGET IC50 5400.0 nM 10.1016/j.bmcl.2007.05.059
None NON-PROTEIN TARGET IC50 5580.0 nM 10.1016/j.bmcl.2010.08.010
None NON-PROTEIN TARGET IC50 5600.0 nM 10.1016/j.bmcl.2009.08.005
None NON-PROTEIN TARGET IC50 5600.0 nM 10.1016/j.bmcl.2009.10.051
None NON-PROTEIN TARGET IC50 5600.0 nM 10.1016/j.bmcl.2012.05.004
None NON-PROTEIN TARGET IC50 5600.0 nM 10.1016/j.ejmech.2011.08.024
None NON-PROTEIN TARGET IC50 5620.0 nM 10.1016/j.bmc.2013.04.004
None NON-PROTEIN TARGET IC50 5730.0 nM 10.1016/j.bmc.2013.11.027
None NON-PROTEIN TARGET IC50 6300.0 nM 10.1021/np5004577
None NON-PROTEIN TARGET IC50 6530.0 nM 10.1016/j.bmc.2016.09.021
None NON-PROTEIN TARGET IC50 6779.0 nM 10.1039/C2MD20275A
None NON-PROTEIN TARGET IC50 7100.0 nM 10.1016/j.bmcl.2015.06.076
None NON-PROTEIN TARGET IC50 7990.0 nM 10.1016/j.ejmech.2015.10.045
None NON-PROTEIN TARGET IC50 8080.0 nM 10.1016/j.ejmech.2016.03.033
None NON-PROTEIN TARGET IC50 8300.0 nM 10.1016/j.ejmech.2011.04.007
None NON-PROTEIN TARGET IC50 8410.0 nM 10.1039/C4MD00536H
None NON-PROTEIN TARGET IC50 8420.0 nM 10.1016/j.ejmech.2016.04.068
None NON-PROTEIN TARGET IC50 9860.0 nM 10.1039/C3MD00192J
None NON-PROTEIN TARGET IC50 9960.0 nM 10.1016/j.bmc.2015.01.006
None NON-PROTEIN TARGET IC50 10000.0 nM 10.1016/j.bmcl.2015.06.076
None NON-PROTEIN TARGET IC50 10680.0 nM 10.1016/j.ejmech.2016.04.068
None NON-PROTEIN TARGET IC50 10800.0 nM 10.1016/j.bmc.2013.11.013
None NON-PROTEIN TARGET IC50 10980.0 nM 10.1039/C4MD00536H
None NON-PROTEIN TARGET IC50 11340.0 nM 10.1016/j.ejmech.2016.04.068
None NON-PROTEIN TARGET IC50 11500.0 nM 10.1016/j.bmc.2013.11.013
None NON-PROTEIN TARGET IC50 11500.0 nM 10.1016/j.ejmech.2011.08.013
None NON-PROTEIN TARGET IC50 12300.0 nM 10.1016/j.bmc.2013.11.013
None NON-PROTEIN TARGET IC50 14080.0 nM 10.1021/jm1014814
None NON-PROTEIN TARGET IC50 15570.0 nM 10.1016/j.ejmech.2014.04.059
None NON-PROTEIN TARGET IC50 19540.0 nM 10.1016/j.ejmech.2013.06.055
None NON-PROTEIN TARGET IC50 19540.0 nM 10.1016/j.ejmech.2016.04.068
None NON-PROTEIN TARGET IC50 21070.0 nM 10.1016/j.bmc.2010.03.077
None NON-PROTEIN TARGET IC50 24910.0 nM 10.1016/j.ejmech.2016.04.068
None NON-PROTEIN TARGET IC50 27710.0 nM 10.1016/j.ejmech.2016.04.068
None NON-PROTEIN TARGET IC50 101000.0 nM 10.1016/j.bmc.2013.11.027
None NON-PROTEIN TARGET IC50 102000.0 nM 10.1039/C3MD00192J
None NON-PROTEIN TARGET Inhibition 70.94 % 10.1016/j.bmc.2013.04.004
None NON-PROTEIN TARGET Inhibition 83.03 % 10.1016/j.bmc.2013.04.004
None NON-PROTEIN TARGET Inhibition nan % 10.1016/j.ejmech.2014.07.033
None NON-PROTEIN TARGET LC50 6310.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 7940.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 10000.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 15800.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 15900.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 20000.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 31600.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 39800.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 50100.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 63100.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 79400.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 100000.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET LC50 nan None 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET Potency 4213.5 nM None
None NON-PROTEIN TARGET Potency 11875.4 nM None
None NON-PROTEIN TARGET Potency 14950.2 nM None
None NON-PROTEIN TARGET Potency 18654.8 nM None
None NON-PROTEIN TARGET TGI 43.8 % 10.1016/j.ejmech.2016.06.030
None NON-PROTEIN TARGET TGI 3160.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 3980.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 4310.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET TGI 4730.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET TGI 5010.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 6310.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 7940.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 10000.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 10320.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET TGI 10420.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET TGI 12600.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 15850.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 15900.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 16360.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET TGI 17330.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET TGI 20000.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI 23550.0 nM 10.1016/j.ejmech.2015.10.053
None NON-PROTEIN TARGET TGI 100000.0 nM 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TGI nan None 10.1016/j.ejmech.2016.02.039
None NON-PROTEIN TARGET TIME 28.05 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 31.9 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 32.5 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 33.2 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 33.3 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 34.4 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 35.0 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 37.4 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 58.0 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 65.0 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 68.0 hr 10.1016/j.ejmech.2016.03.015
None NON-PROTEIN TARGET TIME 79.0 hr 10.1016/j.ejmech.2016.03.015
None No relevant target LogD 3.85 None 10.1016/j.ejmech.2022.114434
None No relevant target LogP 5.0 None 10.1016/j.bmcl.2011.11.061
None No relevant target Solubility 0.005 ug.mL-1 10.1021/jm801050k
None No relevant target Solubility 3270.0 nM 10.1016/j.ejmech.2022.114434
None No relevant target Solubility 5400.0 nM 10.6019/CHEMBL3301361
None No relevant target Solubility 6300.0 nM 10.1016/j.bmcl.2008.04.002
None No relevant target Therm_solubility nan None 10.1021/acs.jmedchem.0c01512
None Unchecked Ac50 5.012 uM None
None Unchecked Ac50 25.12 uM None
None Unchecked Ac50 28.18 uM None
None Unchecked AC50 5011.9 nM None
None Unchecked AC50 25120.0 nM None
None Unchecked AC50 28183.8 nM None
None Unchecked Activity -3.0 % 10.1021/acs.jmedchem.0c01647
None Unchecked Activity 0.16 % 10.1021/acs.jmedchem.2c00520
None Unchecked Activity 0.85 % 10.1021/acs.jmedchem.2c00520
None Unchecked Activity 5.3 % 10.1021/acs.jmedchem.7b01465
None Unchecked Activity 5.8 % 10.1021/acs.jmedchem.7b01465
None Unchecked Activity 7.47 % 10.1021/acs.jmedchem.2c00520
None Unchecked Activity 11.0 % 10.1021/acs.jmedchem.7b01465
None Unchecked Activity 20.0 % 10.1021/acs.jmedchem.0c02253
None Unchecked Activity 42.0 % 10.1021/acs.jmedchem.7b01465
None Unchecked Activity 89.0 % 10.1042/bj20070797
None Unchecked Activity 90.0 % 10.1042/bj20070797
None Unchecked Activity 91.5 % 10.1021/acs.jmedchem.2c00520
None Unchecked Activity 181.0 % 10.1016/j.ejmech.2021.113353
None Unchecked Activity 197.0 % 10.1021/acs.jmedchem.7b01465
None Unchecked Activity 252.0 % 10.1021/acs.jmedchem.7b01465
None Unchecked Activity 382.0 % 10.1016/j.ejmech.2021.113353
None Unchecked Activity nan None 10.1016/j.ejmech.2021.113489
None Unchecked Activity nan None 10.1021/acs.jmedchem.2c00520
None Unchecked Activity nan None None
None Unchecked EC50 4300.0 nM 10.1021/jm801050k
None Unchecked FC 1.0 None 10.1021/jm900607f
None Unchecked FC 10.0 None 10.1016/j.ejmech.2021.113489
None Unchecked FC 38.0 None 10.1016/j.ejmech.2016.03.015
None Unchecked GI50 6.1 nM 10.1021/acs.jmedchem.1c00459
None Unchecked GI50 230.0 nM 10.1016/j.ejmech.2017.09.018
None Unchecked GI50 320.0 nM 10.1016/j.ejmech.2017.09.018
None Unchecked GI50 780.0 nM 10.1039/C7MD00067G
None Unchecked GI50 2250.0 nM 10.1016/j.ejmech.2016.04.048
None Unchecked GI50 3400.0 nM 10.1016/j.bmc.2018.02.009
None Unchecked GI50 5000.0 nM 10.1016/j.bmc.2021.116454
None Unchecked GI50 5360.0 nM 10.1016/j.ejmech.2021.113634
None Unchecked GI50 10000.0 nM 10.1016/j.ejmech.2017.09.018
None Unchecked IC50 1.0 nM 10.1038/nchembio.117
None Unchecked IC50 3.7 ug.mL-1 10.1021/acs.jnatprod.2c00853
None Unchecked IC50 7.9 nM 10.1021/acs.jmedchem.0c02167
None Unchecked IC50 18.0 nM 10.1021/jm801050k
None Unchecked IC50 20.0 nM 10.1021/acs.jmedchem.1c00302
None Unchecked IC50 30.0 nM 10.1016/j.bmc.2014.11.029
None Unchecked IC50 38.0 nM 10.1021/acs.jmedchem.0c02167
None Unchecked IC50 60.0 nM 10.1016/j.bmc.2012.04.047
None Unchecked IC50 60.0 nM 10.1016/j.bmcl.2012.09.004
None Unchecked IC50 60.0 nM 10.1016/j.ejmech.2012.02.007
None Unchecked IC50 63.0 nM 10.1016/j.ejmech.2017.02.062
None Unchecked IC50 95.0 nM 10.1016/j.ejmech.2019.112029
None Unchecked IC50 120.1 nM 10.1016/j.bmc.2009.10.055
None Unchecked IC50 500.0 nM 10.1021/acs.jmedchem.1c02079
None Unchecked IC50 710.0 nM 10.1021/acs.jmedchem.0c01568
None Unchecked IC50 780.0 nM 10.1038/nchembio.117
None Unchecked IC50 1270.0 nM 10.1021/acs.jmedchem.2c01518
None Unchecked IC50 1700.0 nM 10.1016/j.ejmech.2018.11.033
None Unchecked IC50 1730.0 nM 10.1016/j.ejmech.2017.02.041
None Unchecked IC50 2500.0 nM 10.1016/j.ejmech.2020.112779
None Unchecked IC50 3480.0 nM 10.1021/acs.jmedchem.2c01518
None Unchecked IC50 3600.0 nM 10.1021/acs.jnatprod.6b00407
None Unchecked IC50 4430.0 nM 10.1021/acs.jmedchem.0c01733
None Unchecked IC50 5600.0 nM 10.1016/j.ejmech.2019.112016
None Unchecked IC50 8300.0 nM 10.1016/j.bmcl.2008.04.002
None Unchecked IC50 9740.0 nM 10.1016/j.ejmech.2020.112661
None Unchecked IC50 10000.0 nM 10.1016/j.ejmech.2020.113102
None Unchecked IC50 10200.0 nM 10.1016/j.ejmech.2017.10.008
None Unchecked IC50 11270.0 nM 10.1021/acs.jmedchem.0c01512
None Unchecked IC50 12670.0 nM 10.1016/j.bmc.2022.117115
None Unchecked IC50 16440.0 nM 10.1016/j.bmc.2018.03.038
None Unchecked IC50 21170.0 nM 10.1021/acs.jmedchem.0c02026
None Unchecked IC50 34410.0 nM 10.1016/j.ejmech.2017.01.008
None Unchecked IC50 40000.0 nM 10.1016/j.ejmech.2017.08.054
None Unchecked IC50 40000.0 nM 10.1016/j.ejmech.2018.03.001
None Unchecked IC50 40000.0 nM 10.1016/j.ejmech.2020.112942
None Unchecked IC50 55000.0 nM 10.1016/j.bmc.2022.116726
None Unchecked IC50 85000.0 nM 10.1016/j.ejmech.2018.11.061
None Unchecked Inhibition 40.0 % 10.1021/acs.jmedchem.0c02253
None Unchecked Inhibition 45.0 % 10.1021/acs.jmedchem.0c02253
None Unchecked Inhibition 67.0 % 10.1021/acs.jmedchem.0c02253
None Unchecked Inhibition 80.0 % 10.1021/acs.jmedchem.0c02253
None Unchecked Inhibition 100.0 % 10.1021/acs.jmedchem.0c02253
None Unchecked Inhibition nan % 10.1016/j.bmc.2012.03.018
None Unchecked Inhibition nan % 10.1016/j.bmcl.2013.01.096
None Unchecked Inhibition nan % 10.1021/acs.jmedchem.0c02253
None Unchecked Inhibition nan % 10.1038/nchembio.117
None Unchecked Inhibition nan % 10.1039/C8MD00089A
None Unchecked Kd 79.0 nM 10.1182/blood-2009-05-222034
None Unchecked Kd 10000.0 nM 10.1182/blood-2009-05-222034
None Unchecked Kd 30000.0 nM 10.1126/science.aan4368
None Unchecked Potency 4685.9 nM None
None Unchecked Potency 8332.8 nM None
None Unchecked Potency 9349.5 nM None
None Unchecked Potency 9431.3 nM None
None Unchecked Potency 11770.4 nM None
None Unchecked Potency 12589.3 nM None
None Unchecked Potency 14818.0 nM None
None Unchecked Potency 20931.0 nM None
None Unchecked Potency 22387.2 nM None
None Unchecked Potency 23485.0 nM None
None Unchecked Potency 28695.4 nM None
None Unchecked Ratio 5.0 None 10.1021/jm800539g
None Unchecked Ratio 30.0 None 10.1021/jm800539g
None Unchecked Ratio 450.0 None 10.1021/jm800539g
None Unchecked RatioGI50 15.0 None 10.1021/acs.jmedchem.2c00820
None Unchecked Ratio IC50 0.7 None 10.1016/j.bmc.2009.10.055
None Unchecked Ratio IC50 0.92 None 10.1016/j.ejmech.2022.114661
None Unchecked Ratio IC50 1.0 None 10.1021/jm070776b
None Unchecked Ratio IC50 1.16 None 10.1016/j.ejmech.2022.114661
None Unchecked Ratio IC50 1.32 None 10.1016/j.ejmech.2022.114661
None Unchecked Ratio IC50 1.47 None 10.1016/j.ejmech.2022.114661
None Unchecked Ratio IC50 1.5 None 10.1039/C8MD00057C
None Unchecked Ratio IC50 1.6 None 10.1021/acs.jnatprod.9b01282
None Unchecked Ratio IC50 1.83 None 10.1016/j.ejmech.2020.112661
None Unchecked Ratio IC50 1.95 None 10.1016/j.ejmech.2022.114661
None Unchecked Ratio IC50 4.42 None 10.1016/j.bmcl.2012.05.004
None Unchecked Selectivity ratio 2.1 None 10.1016/j.ejmech.2021.113353
None Unchecked TGI nan None 10.1016/j.ejmech.2017.09.018
None Unchecked TIME 0.01667 hr 10.1021/acs.jmedchem.0c02253
None Unchecked TIME 0.08333 hr 10.1021/acs.jmedchem.0c02253
None Unchecked TIME 50.0 hr 10.1016/j.ejmech.2021.113353
None Unchecked TIME 71.0 hr 10.1016/j.ejmech.2021.113353

Metabolism Information