Aulosirazole
AlkaPlorer ID: AK080239
Synonym: None
IUPAC Name: 5-hydroxy-3-methoxybenzo[f][1,2]benzothiazole-4,9-dione
Structure
SMILES: COC1=NSC2=C1C(=O)C1=C(O)C=CC=C1C2=O
InChI: InChI=1S/C12H7NO4S/c1-17-12-8-10(16)7-5(3-2-4-6(7)14)9(15)11(8)18-13-12/h2-4,14H,1H3
InChIKey: SYNUZZXUSLTSQM-UHFFFAOYSA-N
Reference
Hapalosin, a Cyanobacterial Cyclic Depsipeptide with Multidrug-Resistance Reversing Activity
PubChem CID: 9970498
LOTUS: LTS0024162
SuperNatural Ⅲ: SN0358786
COCONUT: CNP0252940
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Aulosira fertilissima | Aulosira | Fortieaceae | Nostocales | Cyanophyceae | Cyanobacteriota | None | Bacteria |
Properties Information
Molecule Weight: 261.258
TPSA？: 76.49000000000001
MolLogP？: 1.6326999999999998
Number of H-Donors: 1
Number of H-Acceptors: 6
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Forkhead box protein O3 | Activity | nan | None | 10.1021/acs.jnatprod.1c01030 |
| Homo sapiens | Indoleamine 2,3-dioxygenase | IC50 | 80.3 | nM | 10.1039/C9MD00208A |
| Homo sapiens | OVCAR-3 | IC50 | 301.0 | nM | 10.1021/acs.jnatprod.1c01030 |