Picolinoylglycine
AlkaPlorer ID: AK082038
Synonym: None
IUPAC Name: 2-(pyridine-2-carbonylamino)acetic acid
Structure
SMILES: O=C(O)CNC(=O)C1=CC=CC=N1
InChI: InChI=1S/C8H8N2O3/c11-7(12)5-10-8(13)6-3-1-2-4-9-6/h1-4H,5H2,(H,10,13)(H,11,12)
InChIKey: MNYZGNSHBPLAFN-UHFFFAOYSA-N
Source
Properties Information
Molecule Weight: 180.163
TPSA？: 79.29
MolLogP？: -0.1040000000000005
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Egl nine homolog 1 | IC50 | 100000.0 | nM | 10.1016/j.bmcl.2006.08.026 |
| Homo sapiens | Egl nine homolog 1 | Inhibition | nan | % | 10.1016/j.bmcl.2010.08.032 |
| Homo sapiens | Hypoxia-inducible factor prolyl hydroxylase 1 | IC50 | 1000000.0 | nM | 10.1016/j.bmcl.2010.08.032 |
| None | Unchecked | Delta Tm | 0.7 | degrees C | 10.1021/jm201417e |
| None | Unchecked | IC50 | 1000000.0 | nM | 10.1021/jm201417e |