deoxyfuconojirimycin
AlkaPlorer ID: AK082231
Synonym: '1,5-Dideoxy-1,5-iminofucitol', '1,2,6-Trideoxy-2,6-imino-D-galactitol'
IUPAC Name: (2R,3R,4R,5S)-2-methylpiperidine-3,4,5-triol
Structure
SMILES: C[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
InChI: InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5-,6-/m1/s1
InChIKey: VYOCYWDJTQRZLC-JGWLITMVSA-N
Reference
New Sugar-Mimic Alkaloids from the Pods of <i>Angylocalyx pynaertii</i>
PubChem CID: 141583703
LOTUS: LTS0055629
SuperNatural Ⅲ: SN0403544-02
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Angylocalyx pynaertii | Angylocalyx | Fabaceae | Fabales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 147.17399999999998
TPSA？: 72.72
MolLogP？: -1.9392
Number of H-Donors: 4
Number of H-Acceptors: 4
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Alpha-L-fucosidase I | Ki | 1700000.0 | nM | 10.1016/S0960-894X(00)80649-6 |
| Homo sapiens | Beta-glucocerebrosidase | Ki | 780000.0 | nM | 10.1016/S0960-894X(00)80648-4 |
| Homo sapiens | Beta-mannosidase | Activity | nan | None | 10.1016/j.bmc.2007.11.036 |
| Homo sapiens | Neutral alpha-glucosidase AB | Ki | 1560000.0 | nM | 10.1016/S0960-894X(00)80648-4 |
| Mus musculus | Splenocyte | Inhibition | 9.0 | % | 10.1016/j.bmc.2007.11.036 |
| Mus musculus | Splenocyte | Inhibition | 58.0 | % | 10.1016/j.bmc.2007.11.036 |
| None | Unchecked | Activity | nan | None | 10.1016/j.bmc.2007.11.036 |
| None | Unchecked | IC50 | nan | None | 10.1016/j.bmc.2007.11.036 |