Eusynstyelamide F
AlkaPlorer ID: AK083209
Synonym: None
IUPAC Name: (2S,3R,4S)-1-(4-aminobutyl)-3-(6-bromo-1H-indol-3-yl)-4-[(6-bromo-1H-indol-3-yl)methyl]-N-[4-(diaminomethylideneamino)butyl]-2,4-dihydroxy-5-oxopyrrolidine-2-carboxamide
Structure
SMILES: N=C(N)NCCCCNC(=O)[C@@]1(O)[C@H](C2=CNC3=CC(Br)=CC=C23)[C@@](O)(CC2=CNC3=CC(Br)=CC=C23)C(=O)N1CCCCN
InChI: InChI=1S/C31H38Br2N8O4/c32-19-5-7-21-18(16-39-24(21)13-19)15-30(44)26(23-17-40-25-14-20(33)6-8-22(23)25)31(45,41(28(30)43)12-4-1-9-34)27(42)37-10-2-3-11-38-29(35)36/h5-8,13-14,16-17,26,39-40,44-45H,1-4,9-12,15,34H2,(H,37,42)(H4,35,36,38)/t26-,30+,31+/m1/s1
InChIKey: RPGMNINLCSRHGB-JZRGNDHQSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 746.5049999999998
TPSA？: 209.37
MolLogP？: 2.880770000000001
Number of H-Donors: 9
Number of H-Acceptors: 6
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Candida albicans | Candida albicans | MIC | 50.0 | ug.mL-1 | 10.1021/np100499c |
| Corynebacterium glutamicum | Corynebacterium glutamicum | MIC | 6.25 | ug.mL-1 | 10.1021/np100499c |
| Escherichia coli | Escherichia coli | MIC | 12.5 | ug.mL-1 | 10.1021/np100499c |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | MIC | 12.5 | ug.mL-1 | 10.1021/np100499c |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 6.25 | ug.mL-1 | 10.1021/np100499c |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 50.0 | ug.mL-1 | 10.1021/np100499c |