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Levamisole

AlkaPlorer ID: AK085016

Synonym: None

IUPAC Name: (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole

Structure

SMILES: C1=CC=C([C@H]2CN3CCSC3=N2)C=C1

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InChI: InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1

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InChIKey: HLFSDGLLUJUHTE-SNVBAGLBSA-N

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Reference

PubChem CID: 26879

CAS: 14769-73-4

SuperNatural Ⅲ: SN0354009-02

NPASS: NPC469974

Properties Information

Molecule Weight: 204.298

TPSA？: 15.6

MolLogP？: 2.1461

Number of H-Donors: 0

Number of H-Acceptors: 3

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus subtilis Bacillus subtilis LD99 nan None 10.1021/np010574x
Bos taurus Alkaline phosphatase, tissue-nonspecific isozyme IC50 19210.0 nM 10.1016/j.bmc.2015.03.054
Bos taurus Alkaline phosphatase, tissue-nonspecific isozyme IC50 19210.0 nM 10.1016/j.ejmech.2016.11.036
Bos taurus Alkaline phosphatase, tissue-nonspecific isozyme Ki 1810.0 nM 10.1016/j.bmc.2015.03.054
Bos taurus Intestinal alkaline phosphatase IC50 400000.0 nM 10.1016/j.bmcl.2016.01.061
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Caenorhabditis elegans Caenorhabditis elegans EC50 4.8 ug.mL-1 10.1021/acs.jnatprod.8b00866
Canis lupus familiaris Canis familiaris AUC 8940.0 ng.hr.mL-1 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris AUC 12200.0 ng.hr.mL-1 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris AUC 18100.0 ng.hr.mL-1 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris CL 8.92 mL.min-1.kg-1 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris Cmax 9691.63 nM 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris Cmax 16299.56 nM 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris F 44.0 % 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris F 64.0 % 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris T1/2 1.3 hr 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris T1/2 1.6 hr 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris T1/2 1.8 hr 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris Tmax 1.8 hr 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris Tmax 4.5 hr 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris Vdss 1.39 L.kg-1 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris Vdss 1.42 L.kg-1 10.1124/dmd.112.045021
Canis lupus familiaris Canis familiaris Vdss 2.64 L.kg-1 10.1124/dmd.112.045021
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Cryptosporidium parvum Cryptosporidium parvum IC50 nan None 10.1016/j.bmc.2010.01.068
Entamoeba histolytica Entamoeba histolytica IC50 nan None 10.1016/j.bmc.2010.01.068
Haemonchus contortus Haemonchus contortus EC100 0.32 ppm 10.1016/j.bmcl.2008.03.071
Haemonchus contortus Haemonchus contortus EC50 15000.0 nM 10.1016/j.bmcl.2004.05.044
Haemonchus contortus Haemonchus contortus EC50 18000.0 nM 10.1016/j.bmcl.2004.05.044
Haemonchus contortus Haemonchus contortus LD99 0.66 uM 10.1016/j.bmcl.2006.11.043
Haemonchus contortus Haemonchus contortus LD99 0.66 uM 10.1016/j.bmcl.2011.05.096
Haemonchus contortus Haemonchus contortus LD99 0.71 uM 10.1016/j.bmcl.2007.10.090
Haemonchus contortus Haemonchus contortus LD99 0.78 ug ml-1 10.1016/j.bmcl.2005.07.044
Haemonchus contortus Haemonchus contortus LD99 1.6 ug ml-1 10.1016/j.bmcl.2005.07.044
Haemonchus contortus Haemonchus contortus LD99 100.0 ug ml-1 10.1016/j.bmcl.2005.07.044
Heligmosomoides polygyrus Heligmosomoides polygyrus Reduction 0.0 % 10.1021/jm00109a015
Heligmosomoides polygyrus Heligmosomoides polygyrus Reduction 60.0 % 10.1021/jm00109a015
Heligmosomoides polygyrus Heligmosomoides polygyrus Reduction 100.0 % 10.1021/jm00109a015
Heteropogon contortus Heteropogon contortus LD99 1.6 ug ml-1 10.1021/np010574x
Homo sapiens Acetylcholinesterase AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Alkaline phosphatase placental type IC50 400000.0 nM 10.1016/j.bmc.2013.09.053
Homo sapiens Alkaline phosphatase placental type IC50 400000.0 nM 10.1016/j.bmcl.2016.01.061
Homo sapiens Alkaline phosphatase, tissue-nonspecific isozyme IC50 5000.0 nM 10.1016/j.bmc.2009.12.012
Homo sapiens Alkaline phosphatase, tissue-nonspecific isozyme IC50 19200.0 nM 10.1016/j.ejmech.2017.11.068
Homo sapiens Alkaline phosphatase, tissue-nonspecific isozyme IC50 20200.0 nM 10.1016/j.ejmech.2018.09.063
Homo sapiens Alkaline phosphatase, tissue-nonspecific isozyme IC50 20210.0 nM 10.1016/j.ejmech.2018.07.002
Homo sapiens Alkaline phosphatase, tissue-nonspecific isozyme Inhibition 40.0 % 10.1016/j.bmcl.2016.01.061
Homo sapiens Alkaline phosphatase, tissue-nonspecific isozyme Ki 16000.0 nM 10.1016/j.bmcl.2008.10.107
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 21000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Beta-1 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile salt export pump AC50 300000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 1000000.0 nM 10.1124/dmd.112.047068
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens CCRF-CEM IC50 250000.0 nM 10.1016/j.ejmech.2014.07.054
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens Dopamine D1 receptor AC50 1600.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D1 receptor Potency 8199.5 nM None
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Epidermal growth factor receptor erbB1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Flap endonuclease 1 Potency 3768.6 nM None
Homo sapiens Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens Glucose transporter Inhibition -0.53 % 10.6019/CHEMBL3433997
Homo sapiens HeLa IC50 250000.0 nM 10.1016/j.ejmech.2014.07.054
Homo sapiens HepG2 Inhibition 11.0 % 10.1038/nature09107
Homo sapiens HERG AC50 18814.8 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Ki nan None None
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Potency 26679.5 nM None
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens AUC 3070.0 ng.hr.mL-1 10.1124/dmd.112.045021
Homo sapiens Homo sapiens CL 1.5 L/hr 10.1124/dmd.112.045021
Homo sapiens Homo sapiens CL 1.75 L/hr 10.1124/dmd.112.045021
Homo sapiens Homo sapiens CL 1.86 L/hr 10.1124/dmd.112.045021
Homo sapiens Homo sapiens CL 7.56 mL.min-1.kg-1 10.1124/dmd.112.045021
Homo sapiens Homo sapiens CL 8.04 mL.min-1.kg-1 10.1124/dmd.112.045021
Homo sapiens Homo sapiens CL 8.25 mL.min-1.kg-1 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Cmax 3289.28 nM 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Cmax 3509.54 nM 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Cmax 4013.71 nM 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Drug excretion 3.0 % 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Drug excretion 70.0 % 10.1124/dmd.112.045021
Homo sapiens Homo sapiens F 61.5 % 10.1124/dmd.112.045021
Homo sapiens Homo sapiens F 62.5 % 10.1124/dmd.112.045021
Homo sapiens Homo sapiens F 64.7 % 10.1124/dmd.112.045021
Homo sapiens Homo sapiens T1/2 5.4 hr 10.1124/dmd.112.045021
Homo sapiens Homo sapiens T1/2 5.6 hr 10.1124/dmd.112.045021
Homo sapiens Homo sapiens T1/2 5.9 hr 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Tmax 1.1 hr 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Tmax 1.5 hr 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Tmax 1.7 hr 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Vdss 3.79 L.kg-1 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Vdss 3.8 L.kg-1 10.1124/dmd.112.045021
Homo sapiens Homo sapiens Vdss 3.83 L.kg-1 10.1124/dmd.112.045021
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Intestinal alkaline phosphatase IC50 5000.0 nM 10.1016/j.bmc.2009.12.012
Homo sapiens Intestinal alkaline phosphatase IC50 20210.0 nM 10.1016/j.ejmech.2017.03.003
Homo sapiens Intestinal alkaline phosphatase IC50 200000.0 nM 10.1016/j.ejmech.2018.09.063
Homo sapiens Intestinal alkaline phosphatase IC50 400000.0 nM 10.1016/j.bmc.2013.09.053
Homo sapiens Kappa opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens MG-63 Activity nan None 10.1016/j.bmc.2013.09.053
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens PC-3 FC 1.028 None 10.1038/nchembio790
Homo sapiens Peroxisome proliferator-activated receptor gamma AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Phospholipase A-2-activating protein IC50 5000.0 nM 10.1016/j.bmc.2009.12.012
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens SAOS-2 Activity 33.0 % 10.1016/j.bmc.2013.09.053
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens Sodium channel protein type V alpha subunit AC50 50000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane A2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Leishmania amazonensis Leishmania amazonensis IC50 nan None 10.1016/j.bmc.2010.01.068
Leishmania donovani Leishmania donovani IC50 nan None 10.1016/j.bmc.2010.01.068
Leishmania infantum Leishmania infantum IC50 nan None 10.1016/j.bmc.2010.01.068
Leishmania major Leishmania major IC50 nan None 10.1016/j.bmc.2010.01.068
Leishmania mexicana Glucose transporter Inhibition -0.34 % 10.6019/CHEMBL3433997
Leishmania mexicana Leishmania mexicana IC50 nan None 10.1016/j.bmc.2010.01.068
Meloidogyne incognita Meloidogyne incognita EC100 20.0 mg/L 10.1021/jf305164m
Meloidogyne incognita Meloidogyne incognita EC50 4.0 ug.mL-1 10.1021/jf305164m
Mus musculus Alkaline phosphatase tissue-nonspecific Inhibition nan % 10.1016/j.bmcl.2016.01.061
Mus musculus L1210 IC50 206000.0 nM 10.1016/j.ejmech.2014.07.054
Mus musculus Mus musculus Activity 0.6 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 1.28 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 1.38 10'7No_unit 10.1016/j.ejmech.2016.07.026
Mus musculus Mus musculus Activity 1.48 10'7No_unit 10.1016/j.ejmech.2016.07.026
Mus musculus Mus musculus Activity 1.94 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 2.06 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 3.71 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 7.87 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 12.49 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 16.94 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 17.33 mg 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 17.86 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 18.3 % 10.1016/j.ejmech.2016.07.026
Mus musculus Mus musculus Activity 26.75 % 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 30.8 % 10.1016/j.ejmech.2016.07.026
Mus musculus Mus musculus Activity 36.2 mg 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 65.3 % 10.1016/j.ejmech.2014.10.081
Mus musculus Mus musculus Activity 88.2 % 10.1016/j.ejmech.2014.10.081
Mus musculus Mus musculus Activity 106.11 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 117.62 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 189.71 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 204.26 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity 254.85 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity nan None 10.1016/j.bmcl.2006.12.091
Mus musculus Mus musculus Activity nan None 10.1016/j.ejmech.2016.07.026
Mus musculus Mus musculus Activity_index 0.081 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity_index 0.89 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity_index 1.53 mg/g 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity_index 3.87 None 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Activity_index 5.46 mg/g 10.1016/j.bmcl.2017.02.046
Mus musculus Mus musculus Change 163.0 % 10.1021/jm00147a008
Mus musculus Mus musculus Increase in footpad thickness 0.2 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.24 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.27 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.29 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.3 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.32 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.33 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.34 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.35 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.37 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.38 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.42 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.44 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.45 mM 10.1021/jm00186a015
Mus musculus Mus musculus Increase in footpad thickness 0.49 mM 10.1021/jm00186a015
Mus musculus Mus musculus LD50 15.0 mg.kg-1 10.1021/jm00186a015
Mus musculus Mus musculus LD50 136.0 mg.kg-1 10.1021/jm00186a015
Mus musculus Mus musculus PFC 570.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 850.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 880.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 970.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1150.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1180.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1200.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1330.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1380.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1390.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1490.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1670.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1800.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1850.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 1870.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 2820.0 None 10.1021/jm00186a015
Mus musculus Mus musculus PFC 3530.0 None 10.1021/jm00186a015
Mus musculus Mus musculus Ratio 1.68 None 10.1016/j.ejmech.2016.07.026
Mus musculus Mus musculus Reduction 43.0 % 10.1021/jm00393a028
Mus musculus Mus musculus Reduction 57.0 % 10.1021/jm00393a028
Mus musculus Mus musculus Reduction 98.0 % 10.1021/jm00393a028
Mus musculus Mus musculus Reduction 100.0 % 10.1021/jm00393a028
Mus musculus Mus musculus Reduction nan None 10.1021/jm00393a028
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Nippostrongylus brasiliensis Nippostrongylus brasiliensis Activity 100.0 % 10.1021/np50070a033
Nippostrongylus brasiliensis Nippostrongylus brasiliensis EC50 210.0 nM 10.1021/np0102307
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Plasmodium falciparum Hexose transporter 1 Inhibition 2.58 % 10.6019/CHEMBL3433997
Plasmodium falciparum Plasmodium falciparum IC50 nan None 10.1016/j.bmc.2010.01.068
Plasmodium falciparum Plasmodium falciparum Inhibition 1.0 % 10.1038/nature09107
Plasmodium falciparum Plasmodium falciparum Inhibition 5.0 % 10.1038/nature09107
Plasmodium falciparum Plasmodium falciparum Inhibition 93.0 % 10.1038/nature09107
Plasmodium falciparum Plasmodium falciparum XC50 622.2 nM 10.1038/nature09107
Pneumocystis carinii Pneumocystis carinii IC50 nan None 10.1016/j.bmc.2010.01.068
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Rattus norvegicus ALB 38700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 41000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 42000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 44000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 326.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 343.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 346.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 355.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 373.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 418.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 50.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 51.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 54.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 57.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 64.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 67.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 80.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 86.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 89.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 98.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 103.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 137.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 143.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 165.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 176.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 193.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Change -55.0 % 10.1021/jm00147a008
Rattus norvegicus Rattus norvegicus Change -9.0 % 10.1021/jm00147a008
Rattus norvegicus Rattus norvegicus Change -3.3 % 10.1021/jm00147a008
Rattus norvegicus Rattus norvegicus Change -1.7 % 10.1021/jm00147a008
Rattus norvegicus Rattus norvegicus Change 230.0 % 10.1021/jm00147a008
Rattus norvegicus Rattus norvegicus CHLORIDE 98.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 98.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 101.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 696.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 725.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 783.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 825.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 843.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 873.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 303.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 366.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 446.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 532.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 533.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 932.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 20330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 27170000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 27330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 28330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 29830000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 30000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.9 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ED25 44.4 mg kg-1 10.1021/jm00147a008
Rattus norvegicus Rattus norvegicus ED25 73.4 mg kg-1 10.1021/jm00147a008
Rattus norvegicus Rattus norvegicus ED25 127.4 mg kg-1 10.1021/jm00147a008
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 20.17 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 22.83 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 174.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1360.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1520.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1526.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1550.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1685.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1773.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 32.73 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.6 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 34.38 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.6 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.62 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 45.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 130000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 133200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 134000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 140700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 144700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 177700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Inhibition 0.0 % 10.1021/jm00367a014
Rattus norvegicus Rattus norvegicus Inhibition 1.0 % 10.1021/jm00367a014
Rattus norvegicus Rattus norvegicus Inhibition 2.0 % 10.1021/jm00367a014
Rattus norvegicus Rattus norvegicus LDH 214.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 220.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 277.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 423.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 504.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 536.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 12.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 12.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 9283.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11350.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 12202.83 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 12224.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 12371.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13503.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 87.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 88.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 88.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 89.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 93.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 94.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.95 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.1 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.23 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.3 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.42 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 25.2 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 384300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 387000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 391700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 395300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 397300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 399000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.17 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.5 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.28 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.07 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.2 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 29.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 85.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 158.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 159.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 166.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 328.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 5.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 5.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 9.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 10.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 12.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 565.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 804.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1106.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1254.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1283.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1292.17 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 112.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 114.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 115.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 118.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 127.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 137.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1056330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1087670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1156000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1193500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1198000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1244330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.92 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.95 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.29 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.36 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.52 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.59 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 55700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 56700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 57700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5320000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5360000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5460000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5880000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5980000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 7380000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.17 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 140.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 140.53 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 140.77 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 141.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.9 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Stimulation 230.0 % 10.1021/jm00367a014
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 14.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 14.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 16.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 22.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 31.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 10570.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 12000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13830.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13850.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 14470.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Potency 631.0 nM None
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Saccharomyces cerevisiae Saccharomyces cerevisiae LD99 nan None 10.1021/np010574x
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.1084 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Teladorsagia circumcincta Teladorsagia circumcincta LD99 nan None 10.1016/j.bmcl.2005.07.044
Toxoplasma gondii Toxoplasma gondii IC50 nan None 10.1016/j.bmc.2010.01.068
Trichomonas vaginalis Trichomonas vaginalis IC50 nan None 10.1016/j.bmc.2010.01.068
Trichostrongylus colubriformis Trichostrongylus colubriformis EC100 10.0 ppm 10.1016/j.bmcl.2008.03.071
Trichostrongylus colubriformis Trichostrongylus colubriformis LD99 nan None 10.1016/j.bmcl.2005.07.044
Trypanosoma brucei 6-phospho-1-fructokinase Potency 8492.1 nM None
Trypanosoma brucei Trypanosoma brucei IC50 nan None 10.1016/j.bmc.2010.01.068
Trypanosoma brucei brucei Trypanosoma brucei brucei IC50 nan None 10.1016/j.bmc.2010.01.068
Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 nan None 10.1016/j.bmc.2010.01.068
Trypanosoma cruzi Trypanosoma cruzi IC50 nan None 10.1016/j.bmc.2010.01.068
None ADMET Activity nan None 10.1016/j.bmc.2013.09.053
None ADMET T1/2 6.0 hr 10.1124/dmd.112.045021
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value 38.3 None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 3.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value 5.9 None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value 29.4 None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value 26.5 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value 8.8 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None NON-PROTEIN TARGET Activity nan None 10.1016/j.ejmech.2016.07.026
None NON-PROTEIN TARGET Hepatotoxicity (acute) 0.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 11.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 61.2 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC50 96000.0 nM 10.1016/j.ejmech.2016.06.044
None NON-PROTEIN TARGET IC50 100000.0 nM 10.1016/j.ejmech.2016.06.044
None NON-PROTEIN TARGET IC50 nan None 10.1016/j.bmc.2010.01.068
None No relevant target LogD7.4 0.81 None 10.6019/CHEMBL3301361
None No relevant target solubility nan None 10.1016/j.bmcl.2016.01.061
None No relevant target Solubility 200000000.0 nM 10.1016/j.bmc.2013.09.053
None Phospholipidosis Phospholipidosis nan None 10.1080/15376510701857262
None Unchecked Activity 88.0 % 10.1007/s00044-013-0780-4
None Unchecked Hepatotoxicity (acute) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 6.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 4392.0 nM None
None Unchecked IC50 13300.0 nM 10.1016/j.bmcl.2012.07.021
None Unchecked IC50 19210.0 nM 10.1016/j.bmcl.2020.127238
None Unchecked IC50 23200.0 nM 10.1016/j.bmc.2013.09.053
None Unchecked IC50 41000.0 nM 10.1016/j.bmcl.2016.01.061
None Unchecked IC50 62900.0 nM 10.1016/j.bmc.2013.09.053
None Unchecked IC50 256000.0 nM 10.1016/j.bmcl.2016.01.061
None Unchecked IC50 nan None None
None Unchecked IFI 0.0 % 10.1038/nature09107
None Unchecked Inhibition 70.0 % 10.1021/acs.jmedchem.9b00164
None Unchecked Ki 2703.0 nM None
None Unchecked Ki 30500.0 nM 10.1016/j.bmc.2013.09.053
None Unchecked Ki 47000.0 nM 10.1016/j.bmcl.2016.01.061
None Unchecked Ki 93000.0 nM 10.1016/j.bmc.2009.08.048
None Unchecked Ki 4000000.0 nM 10.1007/s00044-013-0780-4
None Unchecked Ki nan None None
None Unchecked Ratio IC50 0.1 None 10.1016/j.ejmech.2018.09.063
None Unchecked Ratio IC50 13.0 None 10.1016/j.bmc.2013.09.053

Metabolism Information