Molecule

ZG-1494α

AlkaPlorer ID: AK085448

Synonym: None

IUPAC Name: 3-[(1R,2S,4aS,6S,8aR)-3,4a,6-trimethyl-2-[(E)-4-methylhex-2-en-2-yl]-2,5,6,7,8,8a-hexahydro-1H-naphthalene-1-carbonyl]-5-hydroxy-5-[(4-hydroxyphenyl)methyl]-1H-pyrrol-2-one

Structure

SMILES: CCC(C)/C=C(\C)[C@H]1C(C)=C[C@@]2(C)C[C@@H](C)CC[C@@H]2[C@H]1C(=O)C1=CC(O)(CC2=CC=C(O)C=C2)N=C1O

InChI: InChI=1S/C32H43NO4/c1-7-19(2)14-21(4)27-22(5)16-31(6)15-20(3)8-13-26(31)28(27)29(35)25-18-32(37,33-30(25)36)17-23-9-11-24(34)12-10-23/h9-12,14,16,18-20,26-28,34,37H,7-8,13,15,17H2,1-6H3,(H,33,36)/b21-14+/t19?,20-,26+,27-,28+,31+,32?/m0/s1

InChIKey: DZMMOKIPXHQOJN-KXVCVXEUSA-N

Reference

ZG-1494.ALPHA., a Novel Platelet-activating Factor Acetyltransferase Inhibitor from Penicilium rubrum, Isolation, Structure Elucidation and Biological Activity.

PubChem CID: 6475762

LOTUS: LTS0104432

NPASS: NPC486000

{

NPAtlas: NPA016014

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Talaromyces convolutus	Talaromyces	Trichocomaceae	Eurotiales	Eurotiomycetes	Ascomycota	Fungi	Eukaryota
None	Patricia	Nymphalidae	Lepidoptera	Insecta	Arthropoda	Metazoa	Eukaryota

Properties Information

Molecule Weight: 505.6990000000002

TPSA？: 90.12

MolLogP？: 6.71610000000001

Number of H-Donors: 3

Number of H-Acceptors: 4

RingCount: 4

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Aspergillus fumigatus	Aspergillus fumigatus	Activity	nan	None	10.1021/np990371x
Aspergillus fumigatus	Aspergillus fumigatus	IZ	10.0	mm	10.1021/np990371x
Aspergillus fumigatus	Aspergillus fumigatus	IZ	11.0	mm	10.1021/np990371x
Aspergillus fumigatus	Aspergillus fumigatus	IZ	12.0	mm	10.1021/np990371x
Aspergillus fumigatus	Aspergillus fumigatus	IZ	14.0	mm	10.1021/np990371x
Aspergillus fumigatus	Aspergillus fumigatus	IZ	15.0	mm	10.1021/np990371x
Aspergillus fumigatus	Aspergillus fumigatus	IZ	17.0	mm	10.1021/np990371x
Aspergillus niger	Aspergillus niger	Activity	11.0	mm	10.1021/np990371x
Aspergillus niger	Aspergillus niger	Activity	nan	None	10.1021/np990371x
Aspergillus niger	Aspergillus niger	IZ	9.0	mm	10.1021/np990371x
Aspergillus niger	Aspergillus niger	IZ	10.0	mm	10.1021/np990371x
Aspergillus niger	Aspergillus niger	IZ	11.0	mm	10.1021/np990371x
Aspergillus niger	Aspergillus niger	IZ	13.0	mm	10.1021/np990371x
Aspergillus niger	Aspergillus niger	IZ	15.0	mm	10.1021/np990371x
Aspergillus niger	Aspergillus niger	IZ	16.0	mm	10.1021/np990371x
Candida albicans	Candida albicans	Activity	nan	None	10.1021/np990371x
Candida albicans	Candida albicans	IZ	11.0	mm	10.1021/np990371x
Candida albicans	Candida albicans	IZ	13.0	mm	10.1021/np990371x
Candida albicans	Candida albicans	IZ	14.0	mm	10.1021/np990371x
Candida albicans	Candida albicans	IZ	15.0	mm	10.1021/np990371x
Candida albicans	Candida albicans	IZ	17.0	mm	10.1021/np990371x
Candida albicans	Candida albicans	IZ	18.0	mm	10.1021/np990371x
Candida albicans	Candida albicans	IZ	20.0	mm	10.1021/np990371x
Cryptococcus neoformans	Cryptococcus neoformans	Activity	nan	None	10.1021/np990371x