3-Guanidinylpyridine
AlkaPlorer ID: AK097865
Synonym: 3-Pyridinylguanidine, Pyraxinine
IUPAC Name: 2-pyridin-3-ylguanidine
Structure
SMILES: N=C(N)NC1=CC=CN=C1
InChI: InChI=1S/C6H8N4/c7-6(8)10-5-2-1-3-9-4-5/h1-4H,(H4,7,8,10)
InChIKey: UHLKYVNSNIWKGX-UHFFFAOYSA-N
Reference
Pyraxinine, a Novel Nitrogenous Compound from the Marine Sponge <i>Cymbastela cantharella</i>
PubChem CID: 10419235
CAS: 67087-03-0
LOTUS: LTS0052816
SuperNatural Ⅲ: SN0370563
COCONUT: CNP0217944
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Cymbastela cantharella | Cymbastela | Axinellidae | Axinellida | Demospongiae | Porifera | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 136.158
TPSA？: 74.79
MolLogP？: 0.3869699999999999
Number of H-Donors: 3
Number of H-Acceptors: 2
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Plasminogen | Inhibition | 50.0 | % | 10.1016/s0960-894x(01)00701-6 |
| Homo sapiens | Serotonin 3 (5-HT3) receptor | Ki | 2910.0 | nM | 10.1021/jm9603936 |
| Homo sapiens | Tissue-type plasminogen activator | Inhibition | 50.0 | % | 10.1016/s0960-894x(01)00701-6 |
| Homo sapiens | Urokinase-type plasminogen activator | Inhibition | 50.0 | % | 10.1016/s0960-894x(01)00701-6 |
| None | Unchecked | Inhibition | 50.0 | % | 10.1021/np960562p |