3-hydroxypicolinic acid
AlkaPlorer ID: AK101874
Synonym: None
IUPAC Name: 3-hydroxypyridine-2-carboxylic acid
Structure
SMILES: O=C(O)C1=NC=CC=C1O
InChI: InChI=1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10)
InChIKey: BRARRAHGNDUELT-UHFFFAOYSA-N
Reference
<i>Aloe ferox</i>Leaf Gel Phytochemical Content, Antioxidant Capacity, and Possible Health Benefits
PubChem CID: 13401
CAS: 1007854-00-3
LOTUS: LTS0238574
SuperNatural Ⅲ: SN0033120
COCONUT: CNP0251430
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces virginiae | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 139.11
TPSA？: 70.42
MolLogP？: 0.4853999999999999
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Agaricus bisporus | Tyrosinase | Inhibition | 87.0 | % | 10.1021/jm101266s |
| Bacillus anthracis | Anthrax lethal factor | Inhibition | 43.0 | % | 10.1021/jm101266s |
| Homo sapiens | Arachidonate 5-lipoxygenase | Inhibition | 17.0 | % | 10.1021/jm101266s |
| Homo sapiens | D-amino-acid oxidase | IC50 | 2478000.0 | nM | 10.1021/acs.jmedchem.5b00871 |
| Homo sapiens | D-aspartate oxidase | IC50 | 10000000.0 | nM | 10.1021/acs.jmedchem.5b00871 |
| Homo sapiens | Matrix metalloproteinase-1 | Inhibition | 55.0 | % | 10.1021/jm101266s |
| Homo sapiens | Matrix metalloproteinase-2 | Inhibition | 58.0 | % | 10.1021/jm101266s |
| Homo sapiens | Matrix metalloproteinase 3 | Inhibition | 56.0 | % | 10.1021/jm101266s |
| Homo sapiens | Matrix metalloproteinase 8 | Inhibition | 56.0 | % | 10.1021/jm101266s |
| Homo sapiens | Matrix metalloproteinase 9 | Inhibition | 19.0 | % | 10.1021/jm101266s |
| Mus musculus | Nitric oxide synthase, inducible | Inhibition | 46.0 | % | 10.1021/jm101266s |