Sorazolon D
AlkaPlorer ID: AK103279
Synonym: 'Sorazolon D'
IUPAC Name: (1R,2S)-1,2-dihydroxy-1,2-dimethyl-9H-carbazole-3,4-dione
Structure
SMILES: C[C@@]1(O)C(=O)C(=O)C2=C(NC3=CC=CC=C23)[C@@]1(C)O
InChI: InChI=1S/C14H13NO4/c1-13(18)11-9(10(16)12(17)14(13,2)19)7-5-3-4-6-8(7)15-11/h3-6,15,18-19H,1-2H3/t13-,14-/m1/s1
InChIKey: WNTCGGSSMULYPM-ZIAGYGMSSA-N
Reference
Sorazolons, Carbazole Alkaloids from <i>Sorangium cellulosum</i> Strain Soce375
PubChem CID: 127046037
LOTUS: LTS0125691
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Sorangium cellulosum | Sorangium | Polyangiaceae | Polyangiales | None | Myxococcota | None | Bacteria |
Properties Information
Molecule Weight: 259.261
TPSA？: 90.39
MolLogP？: 0.8917999999999997
Number of H-Donors: 3
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | MIC | None | None | 10.1021/acs.jnatprod.5b00997 |
| Candida albicans | Candida albicans | MIC | None | None | 10.1021/acs.jnatprod.5b00997 |
| Escherichia coli | Escherichia coli | MIC | None | None | 10.1021/acs.jnatprod.5b00997 |
| Micrococcus luteus | Micrococcus luteus | MIC | None | None | 10.1021/acs.jnatprod.5b00997 |
| Mucor hiemalis | Mucor hiemalis | MIC | None | None | 10.1021/acs.jnatprod.5b00997 |
| Mus musculus | L929 | IC50 | None | None | 10.1021/acs.jnatprod.5b00997 |
| Mycolicibacterium smegmatis | Mycolicibacterium smegmatis | MIC | None | None | 10.1021/acs.jnatprod.5b00997 |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | MIC | None | None | 10.1021/acs.jnatprod.5b00997 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | None | None | 10.1021/acs.jnatprod.5b00997 |
| Wickerhamomyces anomalus | Wickerhamomyces anomalus | MIC | None | None | 10.1021/acs.jnatprod.5b00997 |