O(4)-phospho-L-tyrosine
AlkaPlorer ID: AK104053
Synonym: 'O-phospho-L-tyrosine', 'O-phosphono-L-tyrosine', 'O-phosphotyrosine', 'Phosphotyrosine', 'Phosphonotyrosine', 'tyrosine phosphate'
IUPAC Name: (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid
Structure
SMILES: N[C@@H](CC1=CC=C(OP(=O)(O)O)C=C1)C(=O)O
InChI: InChI=1S/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/t8-/m0/s1
InChIKey: DCWXELXMIBXGTH-QMMMGPOBSA-N
Reference
A comprehensive genome‐scale reconstruction of <i>Escherichia coli</i> metabolism—2011
PubChem CID: 30819
CAS: 21820-51-9
LOTUS: LTS0029237
NPASS: NPC326079
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Escherichia coli | Escherichia | Enterobacteriaceae | Enterobacterales | Gammaproteobacteria | Pseudomonadota | None | Bacteria |
Properties Information
Molecule Weight: 261.17
TPSA？: 130.07999999999998
MolLogP？: 0.1125000000000001
Number of H-Donors: 4
Number of H-Acceptors: 4
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Growth factor receptor-bound protein 2 | ID50 | 6.2 | mM | 10.1021/jm00008a017 |
| Homo sapiens | Protein-tyrosine phosphatase 2C | ID50 | 33.0 | mM | 10.1021/jm00008a017 |
| Homo sapiens | Tyrosine-protein kinase LCK | ID50 | 5.0 | mM | 10.1021/jm00008a017 |
| Homo sapiens | Tyrosine-protein kinase SRC | ID50 | 3.5 | mM | 10.1021/jm00008a017 |
| None | Unchecked | ID50 | 2.3 | mM | 10.1021/jm00008a017 |
| None | Unchecked | ID50 | 3.5 | mM | 10.1021/jm00008a017 |